Investigating Bias from Missing Data in an Electronic Health Records-Based Study of Weight Loss After Bariatric Surgery.

Abstract:

PURPOSE:Missing data is common in electronic health records (EHR)-based obesity research. To avoid bias, it is critical to understand mechanisms that underpin missingness. We conducted a survey among bariatric surgery patients in three integrated health systems to (i) investigate predictors of disenrollment and (ii) examine differences in weight between disenrollees and enrollees at 5 years. MATERIALS AND METHODS:We identified 2883 patients who had bariatric surgery between 11/2013 and 08/2014. Patients who disenrolled before their 5-year anniversary were invited to participate in a survey to ascertain reasons for disenrollment and current weight. Logistic regression was used to investigate predictors of disenrollment. Five-year percent weight change distributions were estimated using inverse-probability weighting to adjust for (un)availability of EHR weight data at 5 years among enrollees and survey (non-)response among disenrollees. RESULTS:Among 536 disenrolled patients, 104 (19%) completed the survey. Among 2347 patients who maintained enrollment, 384 (16%) had no weight measurement in the EHR near 5 years. Insurance, age, Hispanic ethnicity, and site predicted disenrollment. Disenrollees had slightly greater weight loss than enrollees. CONCLUSION:We found little evidence of weight loss differences by enrollment status. Collecting information through surveys can be an effective tool to investigate and adjust for missingness in EHR-based studies.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Koffman L,Levis AW,Arterburn D,Coleman KJ,Herrinton LJ,Cooper J,Ewing J,Fischer H,Fraser JR,Johnson E,Taylor B,Theis MK,Liu L,Courcoulas A,Li R,Fisher DP,Amsden L,Haneuse S

doi

10.1007/s11695-021-05226-y

subject

Has Abstract

pub_date

2021-01-19 00:00:00

eissn

0960-8923

issn

1708-0428

pii

10.1007/s11695-021-05226-y

pub_type

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