Incidence of cancer following bariatric surgery: systematic review and meta-analysis.

Abstract:

:Obesity is linked to the development of cancer. Previous studies have suggested that there is a relationship between bariatric surgery and reduced cancer risk. Data sources were from Medline, Embase, and Cochrane Library. From 951 references, 13 studies met the inclusion criteria (54,257 participants). In controlled studies, bariatric surgery was associated with a reduction in the risk of cancer. The cancer incidence density rate was 1.06 cases per 1000 person-years within the surgery groups. In the meta-regression, we found an inverse relationship between the presurgical body mass index and cancer incidence after surgery (beta coefficient -0.2, P < 0.05). Bariatric surgery is associated with reduced cancer risk in morbidly obese people. However, considering the heterogeneity among the studies, conclusions should be drawn with care.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Casagrande DS,Rosa DD,Umpierre D,Sarmento RA,Rodrigues CG,Schaan BD

doi

10.1007/s11695-014-1276-0

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

1499-509

issue

9

eissn

0960-8923

issn

1708-0428

journal_volume

24

pub_type

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