Residual congener pattern of dioxins in human breast milk in southern Vietnam.

Abstract:

:This study evaluated residual congener patterns of dioxin/furan (=PCDD/DF) related to tactical herbicides aerially sprayed over the regions of southern Vietnam through Operation Ranch Hand. The study focused on Cam Chinh (CC) commune, Quang Tri province (an area sprayed with tactical herbicides), and the Cam Phuc (CP) commune, Ha Tinh province (a non-sprayed area). Breast milk samples for analysis were collected in September 2002 and July 2003 from lactating primiparous and multiparous mothers born after the war (<31 years old). We found the levels of each congener in the CC commune were higher than in the CP commune, and determined specificity in the PCDD/DF congener pattern in CC commune samples by cluster analysis. The congener pattern is characterized by higher (the hexa-, the hepta-, and the octa-) chlorinated PCDD/DFs; this appears to be the same profile as that presented by pentachlorophenol (PCP), rather than 2,4,5-trichlorophenoxy acid (2,4,5-T) contaminated with 2,3,7,8-TCDD. A GC/MS study in the 1970s detected the chlorophenols 2,4-di and 2,4,6-trichlorophenol in some Agent Orange samples, which contained, like PCP, a wide variety of PCDD/DF congeners. In this context, it may be expected that certain tactical herbicides contaminated with various chlorophenol impurities, have a unique congener pattern when compared with pure 2,4,5-T formulations.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Tawara K,Nishijo M,Maruzeni S,Nakagawa H,Kido T,Naganuma R,Suzuki H,Nhu DD,Hung NN,Thom le TH

doi

10.1016/j.chemosphere.2011.05.041

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

979-86

issue

7

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(11)00594-7

journal_volume

84

pub_type

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