A test of homogeneity of distributions when observations are subject to measurement errors.

Abstract:

:When the observed data are contaminated with errors, the standard two-sample testing approaches that ignore measurement errors may produce misleading results, including a higher type-I error rate than the nominal level. To tackle this inconsistency, a nonparametric test is proposed for testing equality of two distributions when the observed contaminated data follow the classical additive measurement error model. The proposed test takes into account the presence of errors in the observed data, and the test statistic is defined in terms of the (deconvoluted) characteristic functions of the latent variables. Proposed method is applicable to a wide range of scenarios as no parametric restrictions are imposed either on the distribution of the underlying latent variables or on the distribution of the measurement errors. Asymptotic null distribution of the test statistic is derived, which is given by an integral of a squared Gaussian process with a complicated covariance structure. For data-based calibration of the test, a new nonparametric Bootstrap method is developed under the two-sample measurement error framework and its validity is established. Finite sample performance of the proposed test is investigated through simulation studies, and the results show superior performance of the proposed method than the standard tests that exhibit inconsistent behavior. Finally, the proposed method was applied to real data sets from the National Health and Nutrition Examination Survey. An R package MEtest is available through CRAN.

journal_name

Biometrics

journal_title

Biometrics

authors

Lee D,Lahiri SN,Sinha S

doi

10.1111/biom.13207

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

821-833

issue

3

eissn

0006-341X

issn

1541-0420

journal_volume

76

pub_type

杂志文章
  • A stochastic model for the occurrence of transient ischemic attacks.

    abstract::This paper presents the development, application and evaluation of a stochastic model of the frequency of occurrence of transient ischemic attacks (TIAs). TIAs occur during periods of abnormal arterial activity. The TIAs which occur during a single period of abnormal activity are called a cluster of TIAs. Thus, the nu...

    journal_title:Biometrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Dunn JK,Hardy RJ

    更新日期:1980-03-01 00:00:00

  • The use of score tests for inference on variance components.

    abstract::Whenever inference for variance components is required, the choice between one-sided and two-sided tests is crucial. This choice is usually driven by whether or not negative variance components are permitted. For two-sided tests, classical inferential procedures can be followed, based on likelihood ratios, score stati...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/1541-0420.00032

    authors: Verbeke G,Molenberghs G

    更新日期:2003-06-01 00:00:00

  • Prediction in censored survival data: a comparison of the proportional hazards and linear regression models.

    abstract::Although the analysis of censored survival data using the proportional hazards and linear regression models is common, there has been little work examining the ability of these estimators to predict time to failure. This is unfortunate, since a predictive plot illustrating the relationship between time to failure and ...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Heller G,Simonoff JS

    更新日期:1992-03-01 00:00:00

  • Model selection and inference for censored lifetime medical expenditures.

    abstract::Identifying factors associated with increased medical cost is important for many micro- and macro-institutions, including the national economy and public health, insurers and the insured. However, assembling comprehensive national databases that include both the cost and individual-level predictors can prove challengi...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/biom.12464

    authors: Johnson BA,Long Q,Huang Y,Chansky K,Redman M

    更新日期:2016-09-01 00:00:00

  • Randomization inference with general interference and censoring.

    abstract::Interference occurs between individuals when the treatment (or exposure) of one individual affects the outcome of another individual. Previous work on causal inference methods in the presence of interference has focused on the setting where it is a priori assumed that there is "partial interference," in the sense that...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/biom.13125

    authors: Loh WW,Hudgens MG,Clemens JD,Ali M,Emch ME

    更新日期:2020-03-01 00:00:00

  • Marginal modeling of binary cross-over data.

    abstract::A model specified in terms of linear models for marginal logits and linear models for log-odds ratios is proposed for the analysis of two-period binary cross-over experiments. Hypothesis testing and parameter estimation are facilitated by standard likelihood methodology. Two examples are used to illustrate how the mod...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Becker MP,Balagtas CC

    更新日期:1993-12-01 00:00:00

  • A mixture model for quantum dot images of kinesin motor assays.

    abstract::We introduce a nearly automatic procedure to locate and count the quantum dots in images of kinesin motor assays. Our procedure employs an approximate likelihood estimator based on a two-component mixture model for the image data; the first component has a normal distribution, and the other component is distributed as...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.1541-0420.2010.01467.x

    authors: Hughes J,Fricks J

    更新日期:2011-06-01 00:00:00

  • Drawing inferences for high-dimensional linear models: A selection-assisted partial regression and smoothing approach.

    abstract::Drawing inferences for high-dimensional models is challenging as regular asymptotic theories are not applicable. This article proposes a new framework of simultaneous estimation and inferences for high-dimensional linear models. By smoothing over partial regression estimates based on a given variable selection scheme,...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/biom.13013

    authors: Fei Z,Zhu J,Banerjee M,Li Y

    更新日期:2019-06-01 00:00:00

  • Time series models based on generalized linear models: some further results.

    abstract::This paper considers the problem of extending the classical moving average models to time series with conditional distributions given by generalized linear models. These models have the advantage of easy construction and estimation. Statistical modelling techniques are also proposed. Some simulation results and an ill...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Li WK

    更新日期:1994-06-01 00:00:00

  • Aberrant crypt foci and semiparametric modeling of correlated binary data.

    abstract::Motivated by the spatial modeling of aberrant crypt foci (ACF) in colon carcinogenesis, we consider binary data with probabilities modeled as the sum of a nonparametric mean plus a latent Gaussian spatial process that accounts for short-range dependencies. The mean is modeled in a general way using regression splines....

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.1541-0420.2007.00892.x

    authors: Apanasovich TV,Ruppert D,Lupton JR,Popovic N,Turner ND,Chapkin RS,Carroll RJ

    更新日期:2008-06-01 00:00:00

  • A comment on optimal allocations for bioequivalence studies.

    abstract::A method purporting to provide optimal allocations in bioequivalence studies fails to do so on both statistical and practical grounds. Reasons as to why this is so are given. ...

    journal_title:Biometrics

    pub_type: 评论,杂志文章

    doi:10.1111/j.0006-341x.1999.01314.x

    authors: Senn S,Grieve AP

    更新日期:1999-12-01 00:00:00

  • Memory in coal tits: an alternative model.

    abstract::Jolliffe and Jolliffe (1997, Biometrics 53, 1136-1142) proposed various models for data from an experiment on memory in coal tits. This article describes an alternative model, which fits equally well and which may be simpler to interpret. ...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.0006-341x.1999.00660.x

    authors: Ridout MS

    更新日期:1999-06-01 00:00:00

  • Bayesian inference for two-phase studies with categorical covariates.

    abstract::In this article, we consider two-phase sampling in the situation in which all covariates are categorical. Two-phase designs are appealing from an efficiency perspective since they allow sampling to be concentrated in informative cells. A number of likelihood-based methods have been developed for the analysis of two-ph...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/biom.12019

    authors: Ross M,Wakefield J

    更新日期:2013-06-01 00:00:00

  • Bayesian modeling of multiple lesion onset and growth from interval-censored data.

    abstract::In studying rates of occurrence and progression of lesions (or tumors), it is typically not possible to obtain exact onset times for each lesion. Instead, data consist of the number of lesions that reach a detectable size between screening examinations, along with measures of the size/severity of individual lesions at...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.0006-341X.2004.00217.x

    authors: Dunson DB,Holloman C,Calder C,Gunn LH

    更新日期:2004-09-01 00:00:00

  • A unified parametric regression model for recapture studies with random removals in continuous time.

    abstract::Conditional likelihood based on counting processes are combined with a Horvitz-Thompson estimator to yield a population size estimator that is more efficient than the existing ones. Random removals are allowed in the recapturing process. Simulation studies are shown to assess the performance of the proposed estimators...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.0006-341x.2002.00192.x

    authors: Yip PS,Wang Y

    更新日期:2002-03-01 00:00:00

  • Effects of exposure misclassification on regression analyses of epidemiologic follow-up study data.

    abstract::In epidemiologic studies, subjects are often misclassified as to their level of exposure. Ignoring this misclassification error in the analysis introduces bias in the estimates of certain parameters and invalidates many hypothesis tests. For situations in which there is misclassification of exposure in a follow-up stu...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Reade-Christopher SJ,Kupper LL

    更新日期:1991-06-01 00:00:00

  • A moving blocks empirical likelihood method for longitudinal data.

    abstract::In the analysis of longitudinal or panel data, neglecting the serial correlations among the repeated measurements within subjects may lead to inefficient inference. In particular, when the number of repeated measurements is large, it may be desirable to model the serial correlations more generally. An appealing approa...

    journal_title:Biometrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/biom.12317

    authors: Qiu J,Wu L

    更新日期:2015-09-01 00:00:00

  • Bayesian hierarchical spatially correlated functional data analysis with application to colon carcinogenesis.

    abstract::In this article, we present new methods to analyze data from an experiment using rodent models to investigate the role of p27, an important cell-cycle mediator, in early colon carcinogenesis. The responses modeled here are essentially functions nested within a two-stage hierarchy. Standard functional data analysis lit...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.1541-0420.2007.00846.x

    authors: Baladandayuthapani V,Mallick BK,Young Hong M,Lupton JR,Turner ND,Carroll RJ

    更新日期:2008-03-01 00:00:00

  • Dynamic comparison of Kaplan-Meier proportions: monitoring a randomized clinical trial with a long-term binary endpoint.

    abstract::The approach to early termination for efficacy in a trial where events occur over time but the primary question of interest relates to a long-term binary endpoint is not straightforward. This article considers comparison of treatment groups with Kaplan-Meier (KM) proportions evaluated at increasing times from randomiz...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.1541-0420.2007.00874.x

    authors: Brittain E,Follmann D,Yang S

    更新日期:2008-03-01 00:00:00

  • Efficient experimental designs for the estimation of genetic parameters in plant populations.

    abstract::Procedures for estimating the genetic parameters of plant populations frequently employ progeny testing to ascertain the genotype of maternal plants. However, when experimental resources are limited (e.g., electrophoretic markers), the large progeny sizes required for accurate typing severely restricts the numbers of ...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Brown AH

    更新日期:1975-03-01 00:00:00

  • Relative risk trees for censored survival data.

    abstract::A method is developed for obtaining tree-structured relative risk estimates for censored survival data. The first step of a full likelihood estimation procedure is used in a recursive partitioning algorithm that adopts most aspects of the widely used Classification and Regression Tree (CART) algorithm of Breiman et al...

    journal_title:Biometrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: LeBlanc M,Crowley J

    更新日期:1992-06-01 00:00:00

  • Bayesian partitioning for modeling and mapping spatial case-control data.

    abstract::Methods for modeling and mapping spatial variation in disease risk continue to motivate much research. In particular, spatial analyses provide a useful tool for exploring geographical heterogeneity in health outcomes, and consequently can yield clues as to disease etiology, direct public health management, and generat...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.1541-0420.2008.01193.x

    authors: Costain DA

    更新日期:2009-12-01 00:00:00

  • Comment on "Wang et al. (2005), Robust estimating functions and bias correction for longitudinal data analysis".

    abstract::This note provides a discussion on the manuscript by Wang et al. (2005) who aim to robustify inference for longitudinal data analysis by replacing the ordinary generalized estimating function with an influence-bounded, possibly biased, version. To adjust for the bias of the ensuing robust estimator, the authors provid...

    journal_title:Biometrics

    pub_type: 信件

    doi:10.1111/biom.13263

    authors: Lunardon N,Menardi G

    更新日期:2020-09-01 00:00:00

  • Adaptive line transect sampling.

    abstract::Adaptive line transect sampling offers the potential of improved population density estimation efficiency over conventional line transect sampling when populations are spatially clustered. In adaptive sampling, survey effort is increased when areas of high animal density are located, thereby increasing the number of o...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.0006-341x.2002.00862.x

    authors: Pollard JH,Palka D,Buckland ST

    更新日期:2002-12-01 00:00:00

  • The effect of variance function estimation on nonlinear calibration inference in immunoassay data.

    abstract::Often with data from immunoassays, the concentration-response relationship is nonlinear and intra-assay response variance is heterogeneous. Estimation of the standard curve is usually based on a nonlinear heteroscedastic regression model for concentration-response, where variance is modeled as a function of mean respo...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Belanger BA,Davidian M,Giltinan DM

    更新日期:1996-03-01 00:00:00

  • Adaptive decision making in a lymphocyte infusion trial.

    abstract::We describe an adaptive Bayesian design for a clinical trial of an experimental treatment for patients with hematologic malignancies who initially received an allogeneic bone marrow transplant but subsequently suffered a disease recurrence. Treatment consists of up to two courses of targeted immunotherapy followed by ...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.0006-341x.2002.00560.x

    authors: Thall PF,Inoue LY,Martin TG

    更新日期:2002-09-01 00:00:00

  • Extraction of food consumption systems by nonnegative matrix factorization (NMF) for the assessment of food choices.

    abstract::In Western countries where food supply is satisfactory, consumers organize their diets around a large combination of foods. It is the purpose of this article to examine how recent nonnegative matrix factorization (NMF) techniques can be applied to food consumption data to understand these combinations. Such data are n...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/j.1541-0420.2011.01588.x

    authors: Zetlaoui M,Feinberg M,Verger P,Clémençon S

    更新日期:2011-12-01 00:00:00

  • Multimodal neuroimaging data integration and pathway analysis.

    abstract::With advancements in technology, the collection of multiple types of measurements on a common set of subjects is becoming routine in science. Some notable examples include multimodal neuroimaging studies for the simultaneous investigation of brain structure and function and multi-omics studies for combining genetic an...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/biom.13351

    authors: Zhao Y,Li L,Caffo BS

    更新日期:2020-08-13 00:00:00

  • Small sample inference for fixed effects from restricted maximum likelihood.

    abstract::Restricted maximum likelihood (REML) is now well established as a method for estimating the parameters of the general Gaussian linear model with a structured covariance matrix, in particular for mixed linear models. Conventionally, estimates of precision and inference for fixed effects are based on their asymptotic di...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:

    authors: Kenward MG,Roger JH

    更新日期:1997-09-01 00:00:00

  • FPCA-based method to select optimal sampling schedules that capture between-subject variability in longitudinal studies.

    abstract::A critical component of longitudinal study design involves determining the sampling schedule. Criteria for optimal design often focus on accurate estimation of the mean profile, although capturing the between-subject variance of the longitudinal process is also important since variance patterns may be associated with ...

    journal_title:Biometrics

    pub_type: 杂志文章

    doi:10.1111/biom.12714

    authors: Wu M,Diez-Roux A,Raghunathan TE,Sánchez BN

    更新日期:2018-03-01 00:00:00