Time series models based on generalized linear models: some further results.

abstract：:A critical component of longitudinal study design involves determining the sampling schedule. Criteria for optimal design often focus on accurate estimation of the mean profile, although capturing the between-subject variance of the longitudinal process is also important since variance patterns may be associated with ...

journal_title：Biometrics

authors： Wu M,Diez-Roux A,Raghunathan TE,Sánchez BN

更新日期：2018-03-01 00:00:00

abstract：:Recent developments in the Cormack-Jolly-Seber (CJS) model for analyzing capture-recapture data have focused on allowing the capture and survival rates to vary between individuals. Several methods have been developed in which capture and survival are functions of auxiliary variables that may be discrete, constant over...

journal_title：Biometrics

authors： Bonner SJ,Schwarz CJ

更新日期：2006-03-01 00:00:00

abstract：:Neuroendocrine ensembles communicate with their remote and proximal target cells via an intermittent pattern of chemical signaling. The identification of episodic releases of hormonal pulse signals constitutes a major emphasis of endocrine investigation. Estimating the number, temporal locations, secretion rate, and e...

journal_title：Biometrics

authors： Yang YC,Liu A,Wang Y

更新日期：2006-03-01 00:00:00

abstract：:Bayesian methods are presented for assessing bioequivalence for studies in which a new formulation and a standard are administered simultaneously, and for Latin square designs which compare two or more new formulations to a standard. Two examples illustrate the application of the methods. ...

journal_title：Biometrics

authors： Selwyn MR,Hall NR

更新日期：1984-12-01 00:00:00

abstract：:A transformed Bernstein polynomial that is centered at standard parametric families, such as Weibull or log-logistic, is proposed for use in the accelerated hazards model. This class provides a convenient way towards creating a Bayesian nonparametric prior for smooth densities, blending the merits of parametric and no...

journal_title：Biometrics

authors： Chen Y,Hanson T,Zhang J

更新日期：2014-03-01 00:00:00

abstract：:A wide variety of similarity indices for comparing two assemblages based on species incidence (i.e., presence/absence) data have been proposed in the literature. These indices are generally based on three simple incidence counts: the number of species shared by two assemblages and the number of species unique to each ...

journal_title：Biometrics

authors： Chao A,Chazdon RL,Colwell RK,Shen TJ

更新日期：2006-06-01 00:00:00

abstract：:Ranked set sampling (RSS) utilizes inexpensive auxiliary information about the ranking of the units in a sample to provide a more precise estimator of the population mean of the variable of interest Y, which is either difficult or expensive to measure. However, the ranking may not be perfect in most situations. In thi...

journal_title：Biometrics

authors： Yu PL,Lam K

更新日期：1997-09-01 00:00:00

abstract：:The matrix considered contains four elements, each a function of total number. A special case for which the matrix may be appropriate is when the population may be divided into juveniles and adults, and the survival rates and fecundity are the same for all members of each group. This is true, at least approximatley, f...

journal_title：Biometrics

authors： Cooke D,Leon JA

更新日期：1976-06-01 00:00:00

abstract：:Markov chain models are frequently used for studying event histories that include transitions between several states. An empirical transition matrix for nonhomogeneous Markov chains has previously been developed, including a detailed statistical theory based on counting processes and martingales. In this article, we s...

journal_title：Biometrics

authors： Aalen OO,Borgan O,Fekjaer H

更新日期：2001-12-01 00:00:00

abstract：:In the genetic study of complex traits, especially behavior related ones, such as smoking and alcoholism, usually several phenotypic measurements are obtained for the description of the complex trait, but no single measurement can quantify fully the complicated characteristics of the symptom because of our lack of und...

journal_title：Biometrics

authors： Yu K,Wheeler W,Li Q,Bergen AW,Caporaso N,Chatterjee N,Chen J

更新日期：2010-03-01 00:00:00

abstract：:In diagnostic medicine, estimating the diagnostic accuracy of a group of raters or medical tests relative to the gold standard is often the primary goal. When a gold standard is absent, latent class models where the unknown gold standard test is treated as a latent variable are often used. However, these models have b...

journal_title：Biometrics

authors： Zhang B,Chen Z,Albert PS

更新日期：2012-12-01 00:00:00

abstract：:The use of summary rates of reporting health data is discussed. Directly and indirectly adjusted rates are compared under two models of no interaction. A method of analysis is described whereby a model is first fitted to data in order to investigate assumptions, and subsequently the smoothed rates based on the model a...

journal_title：Biometrics

authors： Freeman DH Jr,Holford TR

更新日期：1980-06-01 00:00:00

abstract：:In a study designed to assess the relationship between a dichotomous exposure and the eventual occurrence of a dichotomous outcome, frequency matching has been proposed as a way to balance the exposure cohorts with respect to the sampling distribution of potential confounding factors. This paper discusses the pooled e...

journal_title：Biometrics

authors： Weinberg CR

更新日期：1985-03-01 00:00:00

abstract：:Vaccine-induced protection may not be homogeneous across individuals. It is possible that a vaccine gives complete protection for a portion of individuals, while the rest acquire only incomplete (leaky) protection of varying magnitude. If vaccine efficacy is estimated under wrong assumptions about such individual leve...

journal_title：Biometrics

authors： Mehtälä J,Dagan R,Auranen K

更新日期：2016-09-01 00:00:00

abstract：:In epidemiologic studies of time to an event, mean lifetime is often of direct interest. We propose methods to estimate group- (e.g., treatment-) specific differences in restricted mean lifetime for studies where treatment is not randomized and lifetimes are subject to both dependent and independent censoring. The pro...

journal_title：Biometrics

authors： Zhang M,Schaubel DE

更新日期：2011-09-01 00:00:00

abstract：:We consider modeling correlated survival data when cluster sizes may be informative to the outcome of interest based on a within-cluster resampling (WCR) approach and a weighted score function (WSF) method. We derive the large sample properties for the WCR estimators under the Cox proportional hazards model. We establ...

journal_title：Biometrics

authors： Cong XJ,Yin G,Shen Y

更新日期：2007-09-01 00:00:00

abstract：:A nonparametric maximum likelihood procedure is given for estimating the survivor function from right-censored data. It approximates the hazard rate by a simple function such as a spline, with different approximations yielding different estimators. A special case is that proposed by Nelson (1969, Journal of Quality Te...

journal_title：Biometrics

authors： Whittemore AS,Keller JB

更新日期：1986-09-01 00:00:00

abstract：:A method purporting to provide optimal allocations in bioequivalence studies fails to do so on both statistical and practical grounds. Reasons as to why this is so are given. ...

journal_title：Biometrics

authors： Senn S,Grieve AP

更新日期：1999-12-01 00:00:00

abstract：:The problem of regression dilution arising from covariate measurement error is investigated for survival data using the proportional hazards model. The naive approach to parameter estimation is considered whereby observed covariate values are used, inappropriately, in the usual analysis instead of the underlying covar...

journal_title：Biometrics

authors： Hughes MD

更新日期：1993-12-01 00:00:00

abstract：:Large amounts of longitudinal health records are now available for dynamic monitoring of the underlying processes governing the observations. However, the health status progression across time is not typically observed directly: records are observed only when a subject interacts with the system, yielding irregular and...

journal_title：Biometrics

authors： Luo Y,Stephens DA,Verma A,Buckeridge DL

更新日期：2020-03-11 00:00:00

abstract：:Spatial data have become increasingly common in epidemiology and public health research thanks to advances in GIS (Geographic Information Systems) technology. In health research, for example, it is common for epidemiologists to incorporate geographically indexed data into their studies. In practice, however, the spati...

journal_title：Biometrics

authors： Huque MH,Bondell HD,Carroll RJ,Ryan LM

更新日期：2016-09-01 00:00:00

abstract：:A broad approach to the design of Phase I clinical trials for the efficient estimation of the maximum tolerated dose is presented. The method is rooted in formal optimal design theory and involves the construction of constrained Bayesian c- and D-optimal designs. The imposed constraint incorporates the optimal design ...

journal_title：Biometrics

authors： Haines LM,Perevozskaya I,Rosenberger WF

更新日期：2003-09-01 00:00:00

abstract：:We present a method for individual and integrative analysis of high dimension, low sample size data that capitalizes on the recurring theme in multivariate analysis of projecting higher dimensional data onto a few meaningful directions that are solutions to a generalized eigenvalue problem. We propose a general framew...

journal_title：Biometrics

authors： Safo SE,Ahn J,Jeon Y,Jung S

更新日期：2018-12-01 00:00:00

abstract：:We consider Bayesian methodology for comparing two or more unlabeled point sets. Application of the technique to a set of steroid molecules illustrates its potential utility involving the comparison of molecules in chemoinformatics and bioinformatics. We initially match a pair of molecules, where one molecule is regar...

journal_title：Biometrics

authors： Dryden IL,Hirst JD,Melville JL

更新日期：2007-03-01 00:00:00

abstract：:We propose a generalized linear mixed model to estimate and test marginal effects on titers repeatedly measured by serial dilution assays. The link is log-log and the titer is assumed to follow a gamma distribution. The parameters are estimated by generalized estimating equations. The marginal effects are tested by me...

journal_title：Biometrics

authors： Bloch J,Chavance M

更新日期：1998-06-01 00:00:00

abstract：:In a period starting around 2007, the Hand, Foot, and Mouth Disease (HFMD) became wide-spreading in China, and the Chinese public health was seriously threatened. To prevent the outbreak of infectious diseases like HFMD, effective disease surveillance systems would be especially helpful to give signals of disease outb...

journal_title：Biometrics

authors： Zhang J,Kang Y,Yang Y,Qiu P

更新日期：2015-09-01 00:00:00

abstract：:Geographic disease surveillance methods identify regions that have higher disease rates than expected. These approaches are generally applied to incident or prevalent cases of disease. In some contexts, disease-related events rather than individuals are the appropriate units of analysis for geographic surveillance. We...

journal_title：Biometrics

authors： Rosychuk RJ,Huston C,Prasad NG

更新日期：2006-06-01 00:00:00

abstract：:In this paper we consider the use of within-subject coefficient of variation (WCV) for assessing the reproducibility or reliability of a measurement. Application to assessing reproducibility of biochemical markers for measuring bone turnover is described and the comparison with intraclass correlation is discussed. Bot...

journal_title：Biometrics

authors： Quan H,Shih WJ

更新日期：1996-12-01 00:00:00

abstract：:For patients with chronic myelogenous leukemia (CML), the effect of elevated blood levels of adenosine deaminase (ADA) is studied as a marker for transitions from stable disease to blast crisis and then to death. Data in the form of snapshots over time, with day, state of disease, and ADA level, are analyzed for 55 pa...

journal_title：Biometrics

authors： Klein JP,Klotz JH,Grever MR

更新日期：1984-12-01 00:00:00

abstract：:In multivariate survival analysis, investigators are often interested in testing for heterogeneity among clusters, both overall and within specific classes. We represent different hypotheses about the heterogeneity structure using a sequence of gamma frailty models, ranging from a null model with no random effects to ...

journal_title：Biometrics

authors： Dunson DB,Chen Z

更新日期：2004-06-01 00:00:00