Abstract：
:We describe the neuropathologic procedure utilized in the Stillbirth Collaborative Research Network (SCRN), focusing on the examination of central nervous system (CNS) in stillbirth (SB). The SCRN was organized to perform a case-control study to determine the scope and causes of SB. Pathologists at all the participating centers agreed on and used the same standardized neuropathologic techniques. Standardized sections were taken and detailed data were collected. Fresh brain tissue was saved for investigative purposes. A total of 663 women with SB were enrolled into the case-control study: 620 delivered a single stillborn, 42 delivered twins, and 1 delivered triplets. Of the 560 (84.5%) who consented to postmortem examination, 465 (70.1%) also gave consent to the examination of the CNS. In the 440 stillborn infants in whom CNS examination was possible, 248 (56.4%) of the brains were intact, 72 were fragmented (16.4%), and 120 (27.3%) were liquefied. In summary, this is the largest prospective study dedicated to investigate the causes of SB and collect essential information and biological samples in the United States. A protocol for neuropathologic examination was instituted, and a brain tissue repository was created to provide samples and related data for future investigations.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Pinar H,Koch MA,Hawkins H,Heim-Hall J,Shehata B,Thorsten VR,Chin S,Willinger M,dela Monte Sdoi
10.1055/s-0031-1284229subject
Has Abstractpub_date
2011-12-01 00:00:00pages
793-802issue
10eissn
0735-1631issn
1098-8785journal_volume
28pub_type
杂志文章,多中心研究abstract：:Two cases of fetal myocardial calcification confirmed postnatally are reported. In contrast to other reports, both infants survived with resolution of calcification by 6 and 12 months. Diagnostic investigations failed to confirm the presence of congenital infection. Both pregnancies were complicated by early cocaine u...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2008-1040740
更新日期：1994-05-01 00:00:00
abstract：:Objective To evaluate if in high-risk non-extracorporeal membrane oxygenation (ECMO)-treated congenital diaphragmatic hernia (CDH) survivors, ventilatory time (VT) is correlated to and can be used as clinical marker of neurodevelopmental delay at 2 years of age. Study Design Cohort study was conducted between 2008 and...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1586120
更新日期：2017-02-01 00:00:00
abstract：:Four hundred sixty-four fetuses underwent real time ultrasound examination within 72 hours before birth to evaluate other factors than the weight formula itself that might influence the accuracy of ultrasound weight estimation. The results indicated that fetal sex had no effect on weight estimation accuracy, but that ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999866
更新日期：1986-07-01 00:00:00
abstract：:To study a possible relation between the use of postnatal glucocorticoids and the incidence and severity of retinopathy of prematurity (ROP), we conducted a retrospective study over a 4-year period that compared data of 161 preterm infants treated with hydrocortisone for bronchopulmonary dysplasia (BPD) with the data ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2000-13437
更新日期：2000-01-01 00:00:00
abstract：INTRODUCTION:Many tertiary neonatal units employ a restricted visiting policy. Webcams have previously been implemented in the neonatal unit setting in several countries. OBJECTIVES:This study aims to determine the views from parents, physicians, and nursing staff before implementation of a webcam system. METHODS:A q...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0034-1376388
更新日期：2015-02-01 00:00:00
abstract：:Percutaneously placed central venous lines have become an intricate part of the medical management of the very low birth weight infant. It is critically important that health care providers involved with the placement of these catheters be familiar with the possible subtle sites for catheter misplacement. We present t...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-994099
更新日期：1997-02-01 00:00:00
abstract：:This study assessed whether the amniotic fluid index (AFI) or the single deepest pocket (SDP) is the best technique to estimate amniotic fluid volume. The AFI and SDP were compared to a dye-determined or directly measured amniotic fluid volume. A PUBMED search from 1990 to 2006 was conducted using the search terms "si...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-2007-986689
更新日期：2007-10-01 00:00:00
abstract：:Two cases of inadvertent third trimester amniocenteses occurring during attempted spinal tap and culdocentesis are presented. These hitherto undescribed occurrences stress potential complications of these invasive diagnostic procedures in the gravid woman. ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994618
更新日期：1993-11-01 00:00:00
abstract：:Exposure to immunosuppressant agents during gestation can affect the fetal immune system. The aim of this study was to evaluate the immune function of infants whose mothers were administered immunosuppressants during pregnancy for the treatment of autoimmune disorders. Circulating lymphocyte subsets and in vitro immun...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-986679
更新日期：2007-09-01 00:00:00
abstract：:A patient with congenital antithrombin III deficiency and a history of thromboembolic events prior to pregnancy was successfully treated with subcutaneous heparin alone throughout two pregnancies. Although adjuvant antithrombin III infusions may have a role in the treatment of this disorder, especially in the peripart...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994748
更新日期：1993-07-01 00:00:00
abstract：:A retrospective review of placental materials (membranes, chorionic plate, umbilical cord) derived from preterm birth is reported. All those studied had intact membranes on admission and did not have spontaneous rupture. Those with preterm labor unresponsive to tocolysis, including those with brief and more prolonged ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999710
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE: This study aimed to the assess risk of respiratory morbidity in neonates born to women with gestational diabetes mellitus (GDM) delivered after labor compared with those delivered without exposure to labor. STUDY DESIGN: This is a secondary analysis of a prospective single-center cohort study of singleton p...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1716483
更新日期：2020-09-06 00:00:00
abstract：:Periventricular leukomalacia (PVL) is a complication of prematurity that carries a high risk of long-term neurologic morbidity. We report the first case, to our knowledge, of unexpected PVL associated with in utero methamphetamine exposure in a 30-week gestation premature infant with a benign hospital course, who subs...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-970079
更新日期：2007-02-01 00:00:00
abstract：:A patient with a homozygous marital partner had three progressively less seriously involved RH-positive babies after a fetal demise due to erythroblastosis. Only the first of the three required fetal transfusions. All were Rh genotypically identical. The case is presented for interest and to illustrate an exception to...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999655
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:We assessed the utility of plasma B-type natriuretic peptide (BNP) in infants with persistent pulmonary hypertension of the newborn (PPHN) in the prediction of inhaled nitric oxide (iNO) requirement. METHODS:This prospective study involved neonates (gestational age ≥ 34 weeks) with PPHN and confirmatory echo...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1548540
更新日期：2015-09-01 00:00:00
abstract：:We report the sixth pregnancy and the first occurrence of twins after liver transplantation, and the second time cyclosporine was used in pregnancy for that indication. The pregnancy was interrupted at 33 weeks, menstrual age, for exacerbation of chronic graft rejection and intrauterine growth retardation of both twin...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999362
更新日期：1991-03-01 00:00:00
abstract：OBJECTIVE: The study aims to assess the impact on neurodevelopmental outcomes of a prolonged hemodynamically significant patent ductus arteriosus (PDA) after a conservative treatment. STUDY DESIGN: This involves the study of two cohorts of preterm infants 23 to 29 weeks gestation, before (n = 29) and after (n = 54) a ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0039-1697674
更新日期：2019-10-10 00:00:00
abstract：OBJECTIVE:The definition of postpartum hemorrhage (PPH) was developed more than 50 years ago. Since then, the obstetric population has changed dramatically. We sought to determine how well we estimated blood loss (EBL) and find thresholds predicting need for transfusion. STUDY DESIGN:We performed a prospective cohort ...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0035-1552940
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:Recent guidelines for neonatal cardiopulmonary resuscitation emphasize the importance of adequate ventilation. In cases of failed resuscitation with positive pressure ventilation, tracheal intubation and chest compressions are recommended. The present study compared the utility of the Miller laryngoscope (Mil...
journal_title：American journal of perinatology
pub_type： 杂志文章,随机对照试验
doi：10.1055/s-0034-1395482
更新日期：2015-07-01 00:00:00
abstract：:Serial ultrasound measurements of the fetus under investigation is an important indicator of fetal growth, and thus fetal health. To assess how reliable those measurements are, a videotape was made, and, utilizing an ultrasound machine that allowed the placement of callipers on the videotape, the dispersion of the mea...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999271
更新日期：1992-09-01 00:00:00
abstract：OBJECTIVE: The aim of the study is to model amplitude-integrated electroencephalography (aEEG) utility to diagnose seizures in common clinical scenarios. STUDY DESIGN: Using reported neonatal seizure prevalence and aEEG sensitivities and specificities, likelihood ratios (LRs) and post-test probabilities were calculate...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1721711
更新日期：2020-12-15 00:00:00
abstract：:There were 107 episodes of pyelonephritis associated with pregnancy or the early puerperium occurring in 103 gravidas investigated retrospectively for information concerning prematurity, low birthweight, and antibiotic susceptibility patterns in the recovered microorganisms. No difference was found in the incidence of...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999800
更新日期：1987-10-01 00:00:00
abstract：:Pregnant patients with severe acute respiratory syndrome coronavirus 2, the virus responsible for the clinical condition newly described in 2019 as coronavirus disease 2019 (COVID-19) and illness severity to warrant intensive care have a complex disease process that must involve multiple disciplines. Guidelines from v...
journal_title：American journal of perinatology
pub_type： 杂志文章,评审
doi：10.1055/s-0040-1713121
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE: This study aimed to analyze whether hospital safety-net burden status is associated with increased risk for severe maternal morbidity (SMM) and postpartum readmissions. STUDY DESIGN: The 2010 to 2014 Nationwide Readmissions Database was utilized for this retrospective cohort study. Hospitals were categorize...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0040-1710544
更新日期：2020-05-05 00:00:00
abstract：:The objective of this article is to report obstetric outcomes of human immunodeficiency virus-1 (HIV-1)-serodiscordant couples who underwent in vitro fertilization and embryo transfer (IVF-ET) with intracytoplasmic sperm injection (ICSI) at a tertiary care center. We reviewed the outcomes of seronegative women after I...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2003-42694
更新日期：2003-08-01 00:00:00
abstract：:Background Late-onset sepsis (LOS) in very low-birth-weight (VLBW) infants is associated with significant morbidity and mortality. Objectives To determine the incidence of LOS workup, association, and predictive value of clinical indicators leading to culture-positive versus culture-negative sepsis workup. Methods All...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-0036-1579648
更新日期：2016-07-01 00:00:00
abstract：:This investigation was undertaken to determine whether histologic examination of the placenta contributed to a better understanding of the cause of intrauterine fetal growth retardation. Placentas were examined of 151 liveborn infants whose birthweights were in the lower 10th percentile for gestational age. One or mor...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-999546
更新日期：1989-01-01 00:00:00
abstract：:A study was undertaken in 372 consecutive patients undergoing non-elective cesarean delivery to explore the incidence and nature of conflicts between physician and patient surrounding the decision to undergo non-elective cesarean delivery; to examine the adequacy of informed consent at the time of non-elective cesarea...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-994319
更新日期：1996-04-01 00:00:00
abstract：:The objective of this article is to prospectively investigate the efficacy of amnioinfusion as a means to reduce febrile morbidity in pregnancies complicated by chorioamnionitis. All laboring patients with a temperature > or =100.1 degrees F were approached for study participation. Exclusion criteria included amnionit...
journal_title：American journal of perinatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1055/s-2007-994085
更新日期：1998-01-01 00:00:00
abstract：:The objective of this paper was to determine if routine postpartum hemoglobin (Hb) determination changes patient management. One thousand patients with a vaginal delivery at Hermann Hospital, Houston, TX, had antepartum Hb testing, and a postpartum Hb for: (1) an antepartum Hb <9.0 mg/dL, (2) an estimated blood loss (...
journal_title：American journal of perinatology
pub_type： 杂志文章
doi：10.1055/s-2007-993881
更新日期：1999-01-01 00:00:00
