Abstract：
OBJECT:Previous studies have shown a relationship between a patient's stage of diffuse axonal injury (DAI) and outcome. However, few studies have assessed whether a specific lesion or type of corpus callosum injury (CCI) influences outcome in patients with DAI. The authors investigated the effect of various DAIs and CCIs on outcome in patients with traumatic brain injury (TBI). METHODS:The authors retrospectively reviewed 78 consecutive patients with DAI who were seen between May 2004 and March 2010. Outcome was evaluated using the Extended Glasgow Outcome Scale (EGOS) 1 year after TBI. Patients with single DAIs had only 1 of the 3 lesions (lobar, CC, or brainstem). Patients with dual DAIs had 2 of these lesions, and those with triple DAIs had all of these lesions. Furthermore, the authors defined single, dual, and triple CCIs by using 3 lesions (genu, body, splenium) in the same way among patients with single (CC) DAIs. Univariate and multivariate logistic regression analyses were performed to evaluate the relationships between these lesions and outcome in patients with DAI. RESULTS:Fifty patients had single DAIs: 34 in the lobar area, 11 in the CC, and 5 in the brainstem. Twenty had dual DAIs, and 8 had triple DAIs. Of the 11 CCIs, 9 were single and 2 were dual CCIs. Among these lesions, only those in the genu were related to disability. The authors dichotomized patients into those with and without genu lesions, regardless of other injuries. Multinomial logistic regression analysis showed that a genu lesion (OR 18, 95% CI 2.2-32; p = 0.0021) and a pupillary abnormality (OR 14, 95% CI 1.6-24; p = 0.0068) were associated with disability (EGOS ≤ 6) in patients with DAI. CONCLUSIONS:Regardless of the number of lesions, the existence of a genu lesion suggested disability 1 year after TBI in patients with DAI.
journal_name
J Neurosurgjournal_title
Journal of neurosurgeryauthors
Matsukawa H,Shinoda M,Fujii M,Takahashi O,Yamamoto D,Murakata A,Ishikawa Rdoi
10.3171/2011.6.JNS11513subject
Has Abstractpub_date
2011-11-01 00:00:00pages
1019-24issue
5eissn
0022-3085issn
1933-0693journal_volume
115pub_type
杂志文章abstract：OBJECT:Renal cell carcinoma (RCC) is an aggressive malignancy that frequently metastasizes. When RCC metastasizes to the spine, significant pain and neurological dysfunction often follow. Because systemic therapy and radiotherapy have a limited effect in controlling spinal disease, surgery is frequently required; howev...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/spi.2001.94.1.0018
更新日期：2001-01-01 00:00:00
abstract：:Consecutive paraffin sections of 105 astrocytomas and 15 oligoastrocytomas were examined for expression of p53, MIB-1 (Ki-67), and proliferating cell nuclear antigen (PCNA). The tumors had been examined previously for genetic abnormalities and by flow cytometry. Regardless of the tumor's stage and grade and the patien...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1997.86.1.0121
更新日期：1997-01-01 00:00:00
abstract：:This series of 228 patients with infantile non-neoplastic hydrocephalus who received either a ventriculoatrial (VA) or a ventriculoperitoneal (VP) shunt before 2 years of age was followed for an average of 7 years, and the results with the two types of shunt were compared. Mortality and infection rates were similar fo...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1979.50.2.0179
更新日期：1979-02-01 00:00:00
abstract：OBJECT:Little has been written about the appropriate diagnosis, investigation, and management of subarachnoid-pleural fistula (SPF). The authors report a series of patients with SPF that developed after resection of spinal tumor and discuss the diagnosis and treatment of this entity. METHODS:Between 1993 and 2002, nin...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/spi.2004.100.4.0332
更新日期：2004-04-01 00:00:00
abstract：OBJECT:Aneurysms located on the distal portion of the posterior inferior cerebellar artery (PICA) are uncommon, and their underlying pathology, natural history, and clinical management are poorly understood. To clarify these lesions more fully, the authors undertook a retrospective analysis of the clinical features and...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2002.97.4.0756
更新日期：2002-10-01 00:00:00
abstract：:The authors report a case in which the lateral C-1 arch fractured in a patient with rheumatoid arthritis and an intact fusion mass; this patient had previously undergone a C1-2 Brooks-type fusion. This unique complication occurred secondary to continued resorption of the C1-2 rheumatoid pannus. Two years after occipit...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/spi.2001.94.1.0137
更新日期：2001-01-01 00:00:00
abstract：:The purpose of this prospective study was twofold: 1) to determine the sensitivity and specificity of computer-derived density spectral array in detecting analog electroencephalographic (EEG) ischemic pattern changes during carotid artery cross-clamping in patients undergoing carotid endarterectomy; and 2) to assess t...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1993.78.6.0884
更新日期：1993-06-01 00:00:00
abstract：OBJECT:Subarachnoid hemorrhage (SAH) with simultaneous acute subdural hematoma (SDH) is a severe disease. The authors' objective was to analyze the incidence, prognosis, and clinical outcome of patients suffering from aneurysm-related SAH and space-occupying acute SDH. METHODS:Between June 1999 and June 2011, data fro...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/2012.11.JNS121435
更新日期：2013-05-01 00:00:00
abstract：:Between April, 1989, and January, 1991, a total of 19 cases of giant aneurysm were treated by the endovascular approach. The patients included seven males and 12 females aged 15 to 72 years. Detachable balloons, occlusion coils, and ethylene vinyl alcohol copolymer liquid were used as embolic materials. In seven cases...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1992.77.1.0037
更新日期：1992-07-01 00:00:00
abstract：OBJECT:Complete avulsion traumatic brachial plexus injuries (BPIs) can be treated using nerve and musculoskeletal reconstruction procedures. However, these interventions are most viable within certain timeframes, and even then they cannot restore all lost function. Little is known about how patients make decisions rega...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2015.2.JNS132686
更新日期：2015-06-01 00:00:00
abstract：:OBJECT The frontal and insular fiber network in humans remains largely unknown. This study investigated the connectivity of the frontal and anterior insular network in humans using cortico-cortical evoked potential (CCEP). METHODS This retrospective analysis included 18 patients with medically intractable focal epilep...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2015.6.JNS15622
更新日期：2016-07-01 00:00:00
abstract：OBJECT:The aim of this study was to examine the effect of postoperative external-beam radiation therapy (EBRT) on disease-specific survival in patients with nonbenign meningiomas. METHODS:The Surveillance, Epidemiology, and End Results (SEER) database from 1988 to 2007 was queried for cases of resected Grades II (atyp...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2012.7.JNS111439
更新日期：2012-10-01 00:00:00
abstract：:OBJECTIVE Results of radial nerve grafting are largely unknown for lesions of the radial nerve that occur proximal to the humerus, including those within the posterior cord. METHODS The authors describe 13 patients with proximal radial nerve injuries who were surgically treated and then followed for at least 24 months...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2014.12.JNS141944.test
更新日期：2016-01-01 00:00:00
abstract：:A 6-year-old girl with a history of a nondisplaced skull fracture diagnosed with computerized tomography (CT) scanning 3 years previously presented with a 6-week history of headaches and decreased use of her right side. On admission CT scans, a large cystic mass was identified in the left frontal lobe region of the br...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/jns.2001.95.6.1040
更新日期：2001-12-01 00:00:00
abstract：:Of 410 patients with refractory herniated lumbar disc disease treated with intradiscal collagenase, 82 (20%) did not respond to enzyme treatment and subsequently underwent surgery. Failure to improve in 6 to 8 weeks was the predominant cause for surgical intervention (53 patients). Increased pain (18 patients), progre...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1986.64.4.0613
更新日期：1986-04-01 00:00:00
abstract：:OBJECTIVEDifferent CSF diversion procedures (ventriculoperitoneal, ventriculoatrial, and lumboperitoneal shunting) have been utilized for the treatment of idiopathic normal pressure hydrocephalus. More recently, endoscopic third ventriculostomy has been suggested as a reasonable alternative in some studies. The purpos...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/2018.5.JNS1875
更新日期：2018-11-01 00:00:00
abstract：:A case is reported in which a fibrosarcoma developed 20 years after irradiation of a pituitary chromophobe adenoma. This rare lesion, like most of the other documented postirradiation pituitary sarcomas, was a combination of fibrosarcoma and pituitary adenoma. These lesions tend to behave in a characteristic fashion, ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1982.56.2.0283
更新日期：1982-02-01 00:00:00
abstract：:Four cases of spontaneous intracranial hematomas caused by unsuspected meningiomas are reported. Nine previous cases were found in the literature and the entire series of 13 cases is reviewed. Because of their unusual clinical presentation, these cases were not diagnosed correctly prior to radiological studies. Hypert...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1976.45.4.0437
更新日期：1976-10-01 00:00:00
abstract：OBJECT:The aim of this study was to assess the histopathological differences between advanced atherosclerotic carotid artery (CA) plaques with signal hyperintensity on T1-weighted MR images and those without, focusing on necrotic core size and intraplaque hemorrhage (IPH). METHODS:Thirty-five patients scheduled for ca...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2010.3.JNS091057
更新日期：2010-10-01 00:00:00
abstract：:The authors discuss routine removal of inferior articular processes and their facets during laminectomy, with wide visualization of the lumbar nerve roots, which has proven to be most successful in relief of the symptoms of lumbar spondylosis. No instance of postoperative vertebral instability has been found. In a con...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1976.44.2.0148
更新日期：1976-02-01 00:00:00
abstract：:The authors present the case of progressive thoracic myelopathy caused by the extensive ossification of the arachnoid membrane and associated intramedullary syrinx. Based on their findings and results of the literature search, they describe a pathological basis for this rare condition, discuss its incidence and sympto...
journal_title：Journal of neurosurgery
pub_type： 杂志文章,评审
doi：10.3171/spi.1999.91.2.0223
更新日期：1999-10-01 00:00:00
abstract：OBJECT:The aim of this study was to target immunotoxin treatment to the high-molecular-weight melanoma-associated antigen (HMW-MAA) and thereby examine any changes in the survival of immunodeficient rats with human glioblastoma multiforme (GBM). METHODS:To target treatment specifically to human glioma cells, Pseudomon...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2004.100.2.0320
更新日期：2004-02-01 00:00:00
abstract：OBJECT:Functional neurosurgical interventions such as deep brain stimulation (DBS) are traditionally performed with the aid of a stereotactic frame. Although frameless techniques have been perceived as less accurate, data from a recent phantom study of a modified frameless approach demonstrated a laboratory accuracy ex...
journal_title：Journal of neurosurgery
pub_type： 临床试验,杂志文章
doi：10.3171/jns.2005.103.3.0404
更新日期：2005-09-01 00:00:00
abstract：:From December 1990 to July 1995, the investigators participated in a prospective clinical study to evaluate the safety of the Guglielmi detachable coil (GDC) system for the treatment of aneurysms. This report summarizes the perioperative results from eight initial interventional neuroradiology centers in the United St...
journal_title：Journal of neurosurgery
pub_type： 传,古典文章,历史文章,杂志文章,多中心研究
doi：10.3171/JNS/2008/108/4/0832
更新日期：2008-04-01 00:00:00
abstract：:The authors report a case of craniopharyngioma in a newborn infant. Marked hydrocephalus of the fetal head was recognized in the pelvimetric roentgenograms of the mother and massive suprasellar calcification was seen in the plain skull films. ...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1975.42.1.0091
更新日期：1975-01-01 00:00:00
abstract：OBJECT:Cochlear neurons are inevitably exposed to traumatic stress during surgical removal of an acoustic neuroma; that event is an important cause of postoperative cochlear neuronal degeneration, with subsequent loss of spiral ganglion cells (SGCs). The object of this study was to investigate whether preoperative phar...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2000.93.1.0090
更新日期：2000-07-01 00:00:00
abstract：:Giant paraclinoidal carotid artery aneurysms frequently require temporary interruption of local circulation to facilitate safe occlusion. Due to brisk retrograde flow through the ophthalmic artery and cavernous branches, simple trapping of the aneurysm by cervical internal carotid artery clamping and intracranial dist...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.1990.73.2.0305
更新日期：1990-08-01 00:00:00
abstract：OBJECT:It is known that the spinal cord can sustain traumatic injury without associated injury of the spinal column in some conditions, such as a flexible spinal column or preexisting narrowed spinal canal. The purpose of this study was to characterize the clinical features and to understand the mechanisms in cases of ...
journal_title：Journal of neurosurgery
pub_type： 评论,信件
doi：
更新日期：2001-04-01 00:00:00
abstract：:By definition, the term "radiosurgery" refers to the delivery of a therapeutic radiation dose in a single fraction, not simply the use of stereotaxy. Multiple-fraction delivery is better termed "stereotactic radiotherapy." There are compelling radiobiological principles supporting the biological superiority of single-...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/jns.2000.93.supplement
更新日期：2000-12-01 00:00:00
abstract：:OBJECT This study explored whether there were differences between the autoimmune disease prevalence rates in unilateral and bilateral moyamoya disease (MMD). METHODS The authors performed a retrospective review of data obtained from the medical records of their hospital, analyzing and comparing the clinical characteri...
journal_title：Journal of neurosurgery
pub_type： 杂志文章
doi：10.3171/2015.4.JNS142936
更新日期：2016-05-01 00:00:00
