γ-Aminobutyric acid (GABA) regulates lipid production and cadmium uptake by Monoraphidium sp. QLY-1 under cadmium stress.

Abstract:

:This study explored the effects of γ-aminobutyric acid (GABA) on the production of biomass and lipids and on the uptake of Cd2+ by microalgae under cadmium (Cd) stress. Compared with the control and Cd stress alone, 2.5 mM GABA increased the maximum lipid content (55.37%) by 49.37% and 9.42%, respectively. GABA application resulted in increased contents of protein and glutathione (GSH) and in upregulated activity of α-amylase but decreased contents of starch, reactive oxygen species (ROS) and Cd2+, with no effect on subsequent biodiesel quality. Additional analysis of GABA further indicated that increased cellular GABA contents could promote lipid synthesis and reduce Cd accumulation by regulating the expression levels of lipogenesis genes, ROS signalling and mineral nutrient uptake under Cd stress. Collectively, these findings show that GABA not only increases lipid production in microalgae but also is involved in the mechanisms by which microalgae respond to Cd stress.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Zhao Y,Song X,Zhong DB,Yu L,Yu X

doi

10.1016/j.biortech.2019.122500

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

122500

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(19)31730-4

journal_volume

297

pub_type

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