Abstract:
BACKGROUND:Each of the 4 randomized clinical trials (RCTs) hosted by the Physical Therapy Clinical Research Network (PTClinResNet) targeted a different disability group (low back disorder in the Muscle-Specific Strength Training Effectiveness After Lumbar Microdiskectomy [MUSSEL] trial, chronic spinal cord injury in the Strengthening and Optimal Movements for Painful Shoulders in Chronic Spinal Cord Injury [STOMPS] trial, adult stroke in the Strength Training Effectiveness Post-Stroke [STEPS] trial, and pediatric cerebral palsy in the Pediatric Endurance and Limb Strengthening [PEDALS] trial for children with spastic diplegic cerebral palsy) and tested the effectiveness of a muscle-specific or functional activity-based intervention on primary outcomes that captured pain (STOMPS, MUSSEL) or locomotor function (STEPS, PEDALS). OBJECTIVE:The focus of these secondary analyses was to determine causal relationships among outcomes across levels of the International Classification of Functioning, Disability and Health (ICF) framework for the 4 RCTs. METHOD AND DESIGN:With the database from PTClinResNet, we used 2 separate secondary statistical approaches-mediation analysis for the MUSSEL and STOMPS trials and regression analysis for the STEPS and PEDALS trials-to test relationships among muscle performance, primary outcomes (pain related and locomotor related), activity and participation measures, and overall quality of life. RESULTS:Predictive models were stronger for the 2 studies with pain-related primary outcomes. Change in muscle performance mediated or predicted reductions in pain for the MUSSEL and STOMPS trials and, to some extent, walking speed for the STEPS trial. Changes in primary outcome variables were significantly related to changes in activity and participation variables for all 4 trials. Improvement in activity and participation outcomes mediated or predicted increases in overall quality of life for the 3 trials with adult populations. LIMITATIONS:Variables included in the statistical models were limited to those measured in the 4 RCTs. It is possible that other variables also mediated or predicted the changes in outcomes. The relatively small sample size in the PEDALS trial limited statistical power for those analyses. CONCLUSIONS:Evaluating the mediators or predictors of change between each ICF level and for 2 fundamentally different outcome variables (pain versus walking) provided insights into the complexities inherent across 4 prevalent disability groups.
journal_name
Phys Therjournal_title
Physical therapyauthors
Mulroy SJ,Winstein CJ,Kulig K,Beneck GJ,Fowler EG,DeMuth SK,Sullivan KJ,Brown DA,Lane CJ,Physical Therapy Clinical Research Network.doi
10.2522/ptj.20110024subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1766-79issue
12eissn
0031-9023issn
1538-6724pii
ptj.20110024journal_volume
91pub_type
杂志文章,随机对照试验相关文献
PHYSICAL THERAPY文献大全abstract:Background:The Carnegie Foundation for the Advancement of Teaching commissioned the Preparation for the Professions Program, a qualitative study of professional education in 5 professions: medicine, nursing, law, engineering, and clergy. These studies identified curricular structures, instructional practices, assessmen...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/pzx061
更新日期:2017-09-01 00:00:00
abstract::Physical therapists (n = 53) and occupational therapists (n = 53) appraised themselves and each other by selecting personal and job-based adjectives (54 pairs) on the Health Team Stereotype Scale. The PTs' self-appraisal differed statistically from the OTs' perception of PTs on 31 adjective pairs (57%). The OTs judged...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/66.5.668
更新日期:1986-05-01 00:00:00
abstract::The purpose of this study was to develop a conceptual framework and a data-collection tool to begin a systematic analysis of the work of the physical therapist. The primary method of data collection was nonparticipant observation of physical therapist-patient treatment sessions. A team of two researchers performed eac...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/70.5.314
更新日期:1990-05-01 00:00:00
abstract::Quadriceps femoris muscle torque was measured in 40 subjects during transcutaneous neuromuscular electrical stimulation (NMES). Three different electrode types (carbonized rubber, sponge, and adhesive) were used on each subject, permitting determination of the factors that influenced the magnitude of quadriceps femori...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/71.10.715
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Current treatments for low back pain have small effects. A research priority is to identify patient characteristics associated with larger effects for specific interventions. OBJECTIVE:The aim of this study was to identify simple clinical characteristics of patients with chronic low back pain who would bene...
journal_title:Physical therapy
pub_type: 杂志文章,随机对照试验
doi:10.2522/ptj.20140014
更新日期:2014-11-01 00:00:00
abstract::The purpose of this study was to determine the consistency of reflex responses of subjects in varying behavioral states. The following selected primitive reflexes were examined in children with spastic quadriplegic cerebral palsy: tonic labyrinthine, asymmetrical tonic neck, symmetrical tonic neck, crossed extension, ...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/62.8.1115
更新日期:1982-08-01 00:00:00
abstract::I surveyed by questionnaire a random sample of 585 physical therapists and the administrators of all accredited and developing entry-level educational programs on record with the American Physical Therapy Association in March 1981 to determine attitudes toward, involvement in, and preparation for teaching as a skill i...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/63.10.1627
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Physical therapists strive to promote children's motor function and the parents' abilities to interact with their children, thus aiming to positively influence the parent-child relationship. This study examined a model for provision of home-based physical therapy within the context of motor play ...
journal_title:Physical therapy
pub_type: 临床试验,杂志文章
doi:10.1093/ptj/78.2.180
更新日期:1998-02-01 00:00:00
abstract:BACKGROUND:Embodied cognition interests physical therapists because efforts to advance motor skills in young infants can affect learning. However, we do not know if simply advancing motor skill is enough to support advances in cognition. OBJECTIVE:The objective was to examine the effect of 2 interventions on the devel...
journal_title:Physical therapy
pub_type: 杂志文章,随机对照试验
doi:10.1093/ptj/pzz031
更新日期:2019-06-01 00:00:00
abstract::The purposes of this investigation of patients with stroke were to 1) determine and compare shoulder lateral rotation range of motion (SLRROM) measured at the threshold of pain on the paretic and nonparetic sides; 2) establish the intrarater and interrater reliability of the measurements; and 3) determine the relation...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/69.9.768
更新日期:1989-09-01 00:00:00
abstract::Aging skeletal muscle exhibits decreases in muscle mass and force and changes in contractile properties. The effects of aging on the physiological characteristics of skeletal muscle are fiber type specific. This review describes the aging process in skeletal muscle; specifically, the effects of aging on the biochemica...
journal_title:Physical therapy
pub_type: 杂志文章,评审
doi:10.1093/ptj/74.1.71
更新日期:1994-01-01 00:00:00
abstract::The purpose of this paper is to discuss general treatment guidelines for treating patients with acute burns and to review pathophysiology of acute burn injuries. I will discuss skin composition briefly, give a review of acute burn pathophysiology and medical treatment, outline the psychological factors physical therap...
journal_title:Physical therapy
pub_type: 杂志文章,评审
doi:10.1093/ptj/64.8.1217
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There has been an increasing focus on vestibular rehabilitation (VR) after traumatic brain injury (TBI) in recent years. However, detailed descriptions of the content of and patient responses to VR after TBI are limited. The purposes of this case series are (1) to describe a modified, group-based...
journal_title:Physical therapy
pub_type: 杂志文章,随机对照试验
doi:10.2522/ptj.20150095
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Diagnoses, to be useful, should be accurate. The purpose of this study using fictitious patients and student judges was to test the theory that diagnostic errors would occur when students saw simulated patients who were similar to previously seen simulated patients. SUBJECTS:Sixty physical thera...
journal_title:Physical therapy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ptj/78.4.375
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:Exercise programs to improve upper extremity function following stroke in the community setting are needed as the length of hospital stay continues to reduce. However, little has been done to increase understanding of how to translate an evidence-based rehabilitation intervention to real-world programs. The p...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/pzab008
更新日期:2021-01-13 00:00:00
abstract::The purpose of this study was to determine whether Bayley Motor Scale scores were stable in infants during the first year of life, that is, whether each individual infant's score was essentially the same at each of the five test ages. Subjects were 15 low-risk and 8 high-risk infants with Bayley Scales of Infant Devel...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/69.10.834
更新日期:1989-10-01 00:00:00
abstract:BACKGROUND:The severity of myelomeningocele (MMC) stems both from a loss of neurons due to neural tube defect and a loss of function in viable neurons due to reduced movement experience during the first year after birth. In young infants with MMC, the challenge is to reinforce excitability and voluntary control of all ...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.2522/ptj.20110074
更新日期:2012-04-01 00:00:00
abstract::Cinematography was used to compare increases in the angle of straight leg raising in relation to the horizontal with increases in the angle of straight leg raising in relation to the pelvis during five minutes of passive straight leg raising. Cinematography was also used to monitor increases in the angle of the pelvis...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/62.9.1269
更新日期:1982-09-01 00:00:00
abstract::The maximal distance walked in a given time period is frequently used as a simple method to evaluate exercise tolerance in patients suffering from chronic obstructive pulmonary disease (COPD). Typically, patients walk on a treadmill or in a corridor at a self-paced speed. Little information is available about the diff...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/70.7.439
更新日期:1990-07-01 00:00:00
abstract::Therapeutic approaches in the pediatric population have generally been less aggressive than those implemented for younger and older adults. Several factors contribute to this, starting with the challenge of engaging infants in the "goal" of therapy, their resistance to initiating behaviors that are uncomfortable or fa...
journal_title:Physical therapy
pub_type: 杂志文章,评审
doi:10.2522/ptj.20100040
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Despite the prevalence of lower limb amputation (LLA), only a small percentage of people with LLA actually receive physical therapy post amputation and are rehabilitated to their full potential level of function. There is a need for the development of a rehabilitation program that targets impairments and lim...
journal_title:Physical therapy
pub_type: 杂志文章,随机对照试验
doi:10.1093/ptj/pzaa008
更新日期:2020-05-18 00:00:00
abstract::The changes in circulatory system behavior occurring in response to exercise stress are integrated by the central neural circulatory control system working in cooperation with local regulatory mechanisms. The regulatory events occurring during exercise may be analyzed using a closed-loop regulatory system model of the...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/61.10.1411
更新日期:1981-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Disability in patients with facial paralysis is the result of impairment or loss of complex and multidimensional functions of the face, including expression of emotions, facial identity, and communication. However, the majority of interventions for facial paralysis are unidimensional and impairme...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.2522/ptj.20100404
更新日期:2012-04-01 00:00:00
abstract::The importance of the physical therapist in the ICU nursery is in early detection and intervention, which is often critical to the success of treatment in any field of medicine or remedial education. Based on information about neurological development, movement is often the first and possibly only external indicator t...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/61.1.45
更新日期:1981-01-01 00:00:00
abstract:Background:Little is known about the attitudes of children living in Central America toward people with disabilities or the effectiveness of a disability awareness program in influencing their knowledge and attitudes. Objective:The study objectives were to evaluate the effectiveness of a disability awareness program i...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.2522/ptj.20160139
更新日期:2017-04-01 00:00:00
abstract::A brief history oa quality assurance efforts preceding the Professional Standards Review Organization law is presented. The goals of the legislation and its requirements and procedures are discussed. Particular emphasis is placed on the PSRO requirements for short-stay hospital review which is the area where PSRO effo...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.1093/ptj/55.12.1315
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:This study investigated changes in the kinematics of elderly people who experienced at least one fall 6 months prior to data collection. The authors hypothesized that, in order to decrease variability of walking, people with a history of falls would show different kinematic adaptations of their w...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.2522/ptj.20050387
更新日期:2006-11-01 00:00:00
abstract::Physical therapists consider many factors in the treatment of patients with musculoskeletal pain. The current literature suggests expectation is an influential component of clinical outcomes related to musculoskeletal pain for which physical therapists frequently do not account. The purpose of this clinical perspectiv...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.2522/ptj.20090306
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Overall functional ability declines over time in people with Parkinson disease (PD). Established benchmarks are needed to allow clinicians and researchers to facilitate meaningful interpretation of data. OBJECTIVE:The purposes of this study were: (1) to report typical values for standard measures of functio...
journal_title:Physical therapy
pub_type: 杂志文章
doi:10.2522/ptj.20100236
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of this multicenter randomized clinical trial was to examine the effectiveness of an extension-oriented treatment approach (EOTA) in a subgroup of subjects with low back pain (LBP) who were hypothesized to benefit from the treatment compared with similar subjects who received a lumbar...
journal_title:Physical therapy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2522/ptj.20060297
更新日期:2007-12-01 00:00:00