Protective antigens against glanders identified by expression library immunization.

abstract：:The development of a safe and efficient multivalent vaccine has great prospects for application. Both rabies virus (RABV) and canine distemper virus (CDV) are highly infectious antigens, causing lethal diseases in domestic dogs and other carnivores worldwide. In this study, a replication-deficient human adenovirus 5 (...

journal_title：Frontiers in microbiology

authors： Yan L,Zhao Z,Xue X,Zheng W,Xu T,Liu L,Tian L,Wang X,He H,Zheng X

更新日期：2020-06-16 00:00:00

abstract：:Biofilms are assemblages of microorganisms attached to each other, or to a surface, and encased in a protective, self-produced matrix. Such associations are now recognized as the predominant microbial growth mode. The physiology of cells in biofilms differs from that of the planktonic cells on which most research has ...

journal_title：Frontiers in microbiology

authors： Penesyan A,Paulsen IT,Gillings MR,Kjelleberg S,Manefield MJ

更新日期：2020-09-02 00:00:00

abstract：:Due to the globally observed increase in antibiotic resistance of bacterial pathogens and the simultaneous decline in new antibiotic developments, the need for alternative inactivation approaches is growing. This is especially true for the treatment of infections with the problematic ESKAPE pathogens, which include En...

journal_title：Frontiers in microbiology

authors： Hoenes K,Bauer R,Meurle T,Spellerberg B,Hessling M

更新日期：2021-01-13 00:00:00

abstract：:Our understanding of how antibodies are generated and function could help develop effective vaccines and antibody-based therapeutics against viruses such as HIV-1, SARS coronavirus (SARS CoV), and Hendra and Nipah viruses (henipaviruses). Although broadly neutralizing antibodies (bnAbs) against the HIV-1 were observed...

journal_title：Frontiers in microbiology

authors： Prabakaran P,Zhu Z,Chen W,Gong R,Feng Y,Streaker E,Dimitrov DS

更新日期：2012-08-02 00:00:00

abstract：:Microorganisms have a wonderful ability to adapt rapidly to new or altered environmental conditions. Enzymes are the basis of metabolism in all living organisms and, therefore, enzyme adaptation plays a crucial role in the adaptation of microorganisms. Comparisons of homology and parallel beneficial mutations in an en...

journal_title：Frontiers in microbiology

authors： Suenaga H

更新日期：2015-09-22 00:00:00

abstract：:The distribution frequency of pathogenic fungi associated with root and crown rot of winter wheat (Triticum aestivum) from 104 fields in the North China Plain was determined during the period from 2013 to 2016. The four most important species identified were Bipolaris sorokiniana (24.0% from roots; 33.7% from stems), ...

journal_title：Frontiers in microbiology

authors： Xu F,Yang G,Wang J,Song Y,Liu L,Zhao K,Li Y,Han Z

更新日期：2018-05-25 00:00:00

abstract：:Pathogens have evolved mechanisms to modulate host cell functions and avoid recognition and destruction by the host damage response. For many years, researchers have focused on proteins as the main effectors used by pathogens to hijack host cell pathways, but only recently with the development of deep RNA sequencing t...

journal_title：Frontiers in microbiology

authors： Bayer-Santos E,Marini MM,da Silveira JF

更新日期：2017-03-21 00:00:00

abstract：:Cyanobacteria are major primary producers in the polar and alpine regions contributing significantly to nitrogen and carbon cycles in the cryosphere. Recent advancements in environmental sequencing techniques have revealed great molecular diversity of microorganisms in cold environments. However, there are no comprehe...

journal_title：Frontiers in microbiology

authors： Chrismas NA,Anesio AM,Sánchez-Baracaldo P

更新日期：2015-10-13 00:00:00

abstract：:The production of pneumocandin B0 is limited by feedback inhibition. Here, low-temperature adaptive laboratory evolution (ALE) was used to improve the production capacity of Glarea lozoyensis by enhancing its membrane permeability. After 50 cycles of ALE, the pneumocandin B0 production of the endpoint strain (ALE50) r...

journal_title：Frontiers in microbiology

authors： Song P,Zhang K,Zhang S,Huang BQ,Ji XJ,Ren LJ,Gao S,Wen JP,Huang H

更新日期：2018-11-21 00:00:00

abstract：:Background: Acute respiratory infections (ARIs) are the leading indication for antibacterial prescriptions despite a viral etiology in the majority of cases. The lack of available diagnostics to discriminate viral and bacterial etiologies contributes to this discordance. Recent efforts have focused on the host respons...

journal_title：Frontiers in microbiology

authors： Poore GD,Ko ER,Valente A,Henao R,Sumner K,Hong C,Burke TW,Nichols M,McClain MT,Huang ES,Ginsburg GS,Woods CW,Tsalik EL

更新日期：2018-12-11 00:00:00

abstract：:The present study aimed to understand the biofilm formation mechanism of Propionibacterium acnes by analyzing the components and structure of the biofilms. P. acnes strains were isolated from the surface of explanted cardiac pacemaker devices that exhibited no clinical signs of infection. Culture tests using a simple ...

journal_title：Frontiers in microbiology

authors： Okuda KI,Nagahori R,Yamada S,Sugimoto S,Sato C,Sato M,Iwase T,Hashimoto K,Mizunoe Y

更新日期：2018-02-14 00:00:00

abstract：:Bacterial spores are extremely resistant life-forms that play an important role in food spoilage and foodborne disease. The return of spores to a vegetative cell state is a three-step process, these being activation, germination, and emergence. High-pressure (HP) processing is known to induce germination in part of th...

journal_title：Frontiers in microbiology

authors： Modugno C,Peltier C,Simonin H,Dujourdy L,Capitani F,Sandt C,Perrier-Cornet JM

更新日期：2020-01-31 00:00:00

abstract：:A notable feature of the Deepwater Horizon oil spill was the unprecedented formation of marine oil snow (MOS) that was observed in large quantities floating on the sea surface and that subsequently sedimented to the seafloor. Whilst the physical and chemical processes involved in MOS formation remain unclear, some stu...

journal_title：Frontiers in microbiology

authors： Suja LD,Chen X,Summers S,Paterson DM,Gutierrez T

更新日期：2019-03-20 00:00:00

abstract：:Pseudorabies virus (PRV) is a member of Alphaherpesvirinae subfamily, its neurotropism and latency infection attract the attention of many scientists. PRV tagged with a fluorescent reporter gene as a tracker has been used to analyze neuronal circuits, including anterograde and retrograde. In this study, we used fosmid...

journal_title：Frontiers in microbiology

authors： Qi H,Wu H,Abid M,Qiu HJ,Sun Y

更新日期：2020-06-11 00:00:00

abstract：:Root-associated fungi are key contributors to ecosystem functioning, however, the factors which determine community assembly are still relatively poorly understood. This study simultaneously quantified the roles of geographical distance, environmental heterogeneity and time in determining root-associated fungal commun...

journal_title：Frontiers in microbiology

authors： Barnes CJ,van der Gast CJ,Burns CA,McNamara NP,Bending GD

更新日期：2016-02-25 00:00:00

abstract：:Bacterial host tropism is a primary determinant of the range of host organisms they can infect. Salmonella serotypes are differentiated into host-restricted and host-adapted specialists, and host-unrestricted generalists. In order to elucidate the underlying molecular mechanisms of host specificity in Salmonella infec...

journal_title：Frontiers in microbiology

authors： Kolenda R,Burdukiewicz M,Schiebel J,Rödiger S,Sauer L,Szabo I,Orłowska A,Weinreich J,Nitschke J,Böhm A,Gerber U,Roggenbuck D,Schierack P

更新日期：2018-08-22 00:00:00

abstract：:Corynebacterium glutamicum is a commonly applied host for the industrial production of amino acids. While valued for its robustness, it is somewhat inferior to competing strains such as Escherichia coli because of the relatively low growth rate of 0.40 h-1 in synthetic, industrial media. Accordingly, adaptive laborato...

journal_title：Frontiers in microbiology

authors： Graf M,Haas T,Müller F,Buchmann A,Harm-Bekbenbetova J,Freund A,Nieß A,Persicke M,Kalinowski J,Blombach B,Takors R

更新日期：2019-08-06 00:00:00

abstract：:The deadwood mycobiome, also known as wood-inhabiting fungi (WIF), are among the key players in wood decomposition, having a large impact on nutrient cycling in forest soils. However, our knowledge of WIF richness and distribution patterns in different forest biomes is limited. Here, we used pyrotag sequencing of the ...

journal_title：Frontiers in microbiology

authors： Purahong W,Pietsch KA,Lentendu G,Schöps R,Bruelheide H,Wirth C,Buscot F,Wubet T

更新日期：2017-04-19 00:00:00

abstract：:Wheat scab caused by F. graminearum is a highly destructive disease that leads to yield reduction and mycotoxin contamination of grains. In this study, an endophytic bacterium of strain YB-130 was isolated from surface sterilized wheat spikes with scab symptoms and identified as Bacillus velezensis by whole genome ann...

journal_title：Frontiers in microbiology

authors： Xu W,Zhang L,Goodwin PH,Xia M,Zhang J,Wang Q,Liang J,Sun R,Wu C,Yang L

更新日期：2020-12-03 00:00:00

abstract：:The filament fungal pathogen, Aspergillus flavus, spreads worldwide and contaminates several important crops. Histone posttranslational modifications are deeply involved in fungal development and virulence, but the biological function of the histone methyltransferase AflSet1 in A. flavus is still unknown. In the study...

journal_title：Frontiers in microbiology

authors： Liu Y,Zhang M,Xie R,Zhang F,Wang S,Pan X,Wang S,Zhuang Z

更新日期：2020-02-18 00:00:00

abstract：:Fusarium Head Blight (FHB) is one of the most devastating diseases of cereals worldwide, threatening both crop production by affecting cereal grain development, and human and animal health by contaminating grains with mycotoxins. Despite that maize residues constitute the primary source of inoculum for Fusarium pathog...

journal_title：Frontiers in microbiology

authors： Cobo-Díaz JF,Baroncelli R,Le Floch G,Picot A

更新日期：2019-02-18 00:00:00

abstract：:The yeast cell is surrounded by a cell wall conferring protection and resistance to environmental conditions that can be harmful. Identify the molecular cues (genes) which shape the biochemical composition and the nanomechanical properties of the cell wall and the links between these two parameters represent a major i...

journal_title：Frontiers in microbiology

authors： Schiavone M,Déjean S,Sieczkowski N,Castex M,Dague E,François JM

更新日期：2017-09-27 00:00:00

abstract：:Purification of the origin recognition complex (ORC) from wild-type budding yeast cells more than two decades ago opened up doors to analyze the initiation of eukaryotic chromosomal DNA replication biochemically. Although revised methods to purify ORC from overproducing cells were reported later, purification of mutan...

journal_title：Frontiers in microbiology

authors： Kawakami H,Ohashi E,Tsurimoto T,Katayama T

更新日期：2016-04-18 00:00:00

abstract：:The use of antibiotics in farm management (growing crops and raising animals) has become a major area of concern. Its implications is the consequent emergence of antibiotic resistant bacteria (ARB) and accordingly their access into the human food chain with passage of antibiotic resistance genes (ARG) to the normal hu...

journal_title：Frontiers in microbiology

authors： Osman K,Badr J,Al-Maary KS,Moussa IM,Hessain AM,Girah ZM,Abo-Shama UH,Orabi A,Saad A

更新日期：2016-11-22 00:00:00

abstract：:Corynebacterium glutamicum is a natural producer of the C50 carotenoid decaprenoxanthin. The crtEcg0722crtBIYEb operon comprises most of its genes for terpenoid biosynthesis. The MarR-type regulator encoded upstream and in divergent orientation of the carotenoid biosynthesis operon has not yet been characterized. This...

journal_title：Frontiers in microbiology

authors： Henke NA,Heider SAE,Hannibal S,Wendisch VF,Peters-Wendisch P

更新日期：2017-04-24 00:00:00

abstract：:Background: The gut microbiota is increasingly recognized as playing an important role in the development of obesity, but the influence of gender remains elusive. Using a large cohort of Chinese adults, our study aimed to identify differences in gut microbiota as a function of body mass index (BMI) and investigate gen...

journal_title：Frontiers in microbiology

authors： Gao X,Zhang M,Xue J,Huang J,Zhuang R,Zhou X,Zhang H,Fu Q,Hao Y

更新日期：2018-06-22 00:00:00

abstract：:Fonsecaea pedrosoi is a dematiaceous fungus and the main causative agent of chromoblastomycosis that is a chronic disease usually affecting the human skin and subcutaneous tissues, which causes deformations and incapacities, being frequently refractory to available therapies. A typical globe-shaped, multiseptated and ...

journal_title：Frontiers in microbiology

authors： Palmeira VF,Goulart FRV,Granato MQ,Alviano DS,Alviano CS,Kneipp LF,Santos ALS

更新日期：2018-06-29 00:00:00

abstract：:Infections by methicillin-resistant Staphylococcus aureus (MRSA) are gradually increasing in the community. In this study, we investigated a total of 162 food samples including 112 ready-to-eat (RTE) foods and 40 processed raw meat and fish samples collected from retail vendors in Dhaka, Bangladesh and determined the ...

journal_title：Frontiers in microbiology

authors： Islam MA,Parveen S,Rahman M,Huq M,Nabi A,Khan ZUM,Ahmed N,Wagenaar JA

更新日期：2019-03-14 00:00:00

abstract：:Deoxynivalenol (DON), a common mycotoxin of type B trichothecene, is produced mainly by several Fusarium species. DON causes great losses in farming and poses severe safety risks to human and animal health. Thus, DON contamination in cereals and DON toxicity are of worldwide concern. In this study, we screened the bac...

journal_title：Frontiers in microbiology

authors： Wang Y,Wang G,Dai Y,Wang Y,Lee YW,Shi J,Xu J

更新日期：2020-01-08 00:00:00

abstract：:Storm events impact freshwater microbial communities by transporting terrestrial viruses and other microbes to freshwater systems, and by potentially resuspending microbes from bottom sediments. The magnitude of these impacts on freshwater ecosystems is unknown and largely unexplored. Field studies carried out at two ...

journal_title：Frontiers in microbiology

authors： Williamson KE,Harris JV,Green JC,Rahman F,Chambers RM

更新日期：2014-03-14 00:00:00