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Seasonal influenza vaccination reminders for children with high-risk conditions: a registry-based randomized trial.

Abstract：

BACKGROUND:Children with chronic conditions have an increased risk of complications from influenza and have low influenza vaccination rates. PURPOSE:To assess the feasibility and effectiveness of using a statewide immunization information system (IIS) for seasonal influenza vaccine reminders from local health departments (LHDs) targeting children with high-risk conditions. DESIGN:A randomized community intervention. SETTING/PARTICIPANTS:The study was conducted in a population of 3618 children aged 24-60 months with a high-risk condition residing in three Michigan counties. Children were identified using a statewide IIS in October 2008. INTERVENTION:Children were randomized to intervention (reminder) or control (no reminder) groups. Reminders for seasonal influenza vaccination were mailed by LHDs in November 2008. MAIN OUTCOME MEASURES:Feasibility of notification (address validity, address deliverability) was assessed (November 2008-February 2009), and frequencies of notification feasibility measures were determined (analyses conducted in 2010). Effectiveness of notification (seasonal influenza vaccine receipt) was assessed using bivariate logistic regression. RESULTS:Among 3618 children with a high-risk condition, 2730 (75.5%) had not received a 2008-2009 influenza vaccination and were eligible at the time of notification. Among children assigned to the reminder group (n=1374), 42.6% had an address determined to be either invalid, undeliverable, or both. Among those with valid addresses (n=2001), a greater percentage of children with deliverable reminders received at least one influenza vaccination (30.8%) during the outcome observation period than did children assigned to no reminder (24.3%, OR=1.39, 95% CI=1.13, 1.72); children with an undeliverable reminder had an influenza vaccination rate (22.8%) similar to children assigned to no reminder. CONCLUSIONS:Receipt of a reminder was positively associated with seasonal influenza vaccination. However, more than 40% of children assigned to receive a reminder were determined to have an invalid or undeliverable address, emphasizing the need for increased quality of IIS contact information. TRIAL REGISTRATION:This study is registered at www.ClinicalTrials.gov NCT01431183.

journal_name

Am J Prev Med

journal_title

American journal of preventive medicine

authors

Dombkowski KJ,Harrington LB,Dong S,Clark SJ

doi

10.1016/j.amepre.2011.09.028

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

71-5

issue

eissn

0749-3797

issn

1873-2607

pii

S0749-3797(11)00741-0

journal_volume

pub_type

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Seasonal influenza vaccination reminders for children with high-risk conditions: a registry-based randomized trial.