Abstract：
:Ergothioneine (ET) is a natural compound which humans and other vertebrates cannot synthesize themselves; it must be absorbed from food in which it is distributed very unevenly. In general, ET is considered an intracellular antioxidant. However, the precise physiological purpose of ET and the consequences of ET deficiency are still unclear. The ergothioneine transporter ETT (old name OCTN1; human gene symbol SLC22A4) is a powerful and highly specific transporter for the uptake of ET. Cells lacking ETT do not accumulate ET, since the plasma membrane is virtually impermeable for this hydrophilic zwitterion compound. The existence of an evolutionary conserved ergothioneine transporter implies a beneficial role for ET. ETT is the first and so far only biomarker of ET activity. Only cells with strong expression of ETT can accumulate ET to high levels. In the human body, the ability to absorb, distribute, and retain ET depends entirely on this transporter. Blockade or inactivation of ETT in animal models may be essential to at last understand the function of ET. In this review of ETT, the focus is on substrate specificity, subcellular localization, human expression profile and expression profiles across species.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Gründemann Ddoi
10.1016/j.ypmed.2011.12.001subject
Has Abstractpub_date
2012-05-01 00:00:00pages
S71-4eissn
0091-7435issn
1096-0260pii
S0091-7435(11)00479-8journal_volume
54 Supplpub_type
杂志文章,评审abstract：:The Patient Protection and Affordable Care Act (ACA) has increased insurance coverage among underserved individuals, but the effect of ACA on cancer diagnosis is currently debated, particularly in Medicaid non-expansion states. Therefore, we aimed to assess the effect of ACA implementation on stage at diagnosis among ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.06.006
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:We report process data on the feasibility of delivering a clinical preventive nutrition intervention that was effective in increasing participants' consumption of fruits and vegetables. We also examine relationships between process variables and study outcomes. METHODS:We randomly assigned six practice site...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.2001.0863
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:As part of a 3-year demonstration project to improve pneumococcal polysaccharide vaccine (PPV) coverage among older adults, the Minnesota Department of Health conducted a baseline evaluation of knowledge, attitudes, and beliefs among the general public regarding PPV. METHODS:A random-digit dialing telephone...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.2001.0839
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:Recognition that early sun exposure is an important risk factor for cutaneous melanoma in white populations has led to efforts to reduce children's sun exposure. 'Kidskin' was a non-randomized, school-based sun protection intervention trial in Perth, Western Australia (1995-1999). Its aim was to determine th...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2005.11.002
更新日期：2006-01-01 00:00:00
abstract：:Electronic cigarettes ("e-cigs") have recently gained in popularity, but their health risks, including dependence potential are unclear. This study analyzed the adult database from the Wave 1 Population Assessment of Tobacco and Health (PATH) Study, a nationally representative survey of tobacco use in the United State...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2017.04.001
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:This study investigated the cost-effectiveness of installing sidewalks to increase levels of transport-walking. METHODS:Secondary analysis using logistic regression established the association of sidewalks with transport-walking using two transport-walking thresholds of 150 and 60 min/week using Western Aust...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2014.07.041
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:Numerous studies have observed higher rates of smoking among adults with mental health conditions. We examined posttraumatic stress disorder (PTSD) and smoking over a 7-9year period among adults with firsthand exposure to the 9/11 attacks enrolled in the World Trade Center Health Registry. METHOD:Data were c...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2015.01.023
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:To determine whether formulating specific plans with regard to sunscreen use can influence parental sun protection behavior (i.e., applying sunscreen to their child). METHOD:In the spring of 2005, an electronic survey on sun protection behavior was performed among 436 parents in the Netherlands. Participants...
journal_title：Preventive medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ypmed.2008.02.025
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Few comprehensive pedestrian safety interventions for primary-school-age children have been developed and evaluated. This paper reports the impact of the 3-year (1995-1997) Child Pedestrian In jury Prevention Project (CPIPP) on a cohort of 1603 children followed from age 6 to 9 years. This multicomponent pro...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1999.0622
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:Although several epidemiologic investigations have suggested a protective role of green tea against cardiovascular diseases and cancer, few studies examined how consumption of green tea was associated with intake of other dietary factors. METHODS:In the winters of 1989-1991, 880 men ages 40-49 years were ra...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1997.0194
更新日期：1997-09-01 00:00:00
abstract：:Health warnings are a promising strategy for reducing consumption of sugar-sweetened beverages (SSBs), but uncertainty remains about how to design warnings to maximize their impact. Warnings already implemented in Latin America use nutrient disclosures, while proposed U.S. warnings would describe the health effects of...
journal_title：Preventive medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ypmed.2019.02.010
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to determine the follow-up for women after receiving an abnormal Pap test before and after the updated American Society of Colposcopic and Cervical Pathology (ASCCP) guidelines for management of abnormal cytology. METHODS:In 1999 and 2004, women who had been enrolled in a US h...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2009.11.005
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To examine the viability of monetary incentives to increase fitness-center use and maintain/improve the Body Mass Indexes (BMIs) of first-year students over the fall semester. METHOD:Randomized-controlled trial with no-treatment and incentive conditions involving 117 first-year students. For 12 weeks, studen...
journal_title：Preventive medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ypmed.2012.12.020
更新日期：2013-03-01 00:00:00
abstract：:Poverty has consistently been linked to poor mental health and risky health behaviors, yet few studies evaluate the effectiveness of programs and policies to address these outcomes by targeting poverty itself. We test the hypothesis that the earned income tax credit (EITC)-the largest U.S. poverty alleviation program-...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2020.106223
更新日期：2020-10-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ypmed.2016.08.008
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:The aim of the current study was to examine the interrelationship between certain cardiovascular disease (CVD) risk factors and overweight, as well as to provide some indication on the prevalence of underweight, overweight and obesity in primary schoolchildren in urban Turkey. METHODS:1044 randomly selected...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.11.029
更新日期：2005-08-01 00:00:00
abstract：BACKGROUND:We examined the effect of sociodemographic factors on the receipt of mammography, colorectal cancer screening, and influenza vaccinations by women enrolled in two Medicare+Choice health plans. METHODS:Administrative and survey data for 2,698 female health plan members was analyzed using multivariate logisti...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.02.041
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:Afterschool programs are an important setting in which to promote children's physical activity. This study examines the association of environmental and policy characteristics on the moderate-to-vigorous physical activity and sedentary behavior of children attending afterschool programs. METHODS:A total of ...
journal_title：Preventive medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ypmed.2014.09.010
更新日期：2014-12-01 00:00:00
abstract：:High-risk human papillomavirus (hrHPV) assessment as a primary screening test improves sensitivity but decreases specificity. Determining risk for cervical abnormalities and adapting policy accordingly may improve the balance between screening benefits and harms. Our aim is to assess the value of factors other than HP...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.105927
更新日期：2020-01-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.09.013
更新日期：2005-06-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/s0091-7435(03)00120-8
更新日期：2003-09-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2010.09.003
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:To estimate the prevalence of physical activity (PA) and associated variables in the Moroccan adult population. METHODS:Population-based, May 2008 survey of a representative sample of Moroccan adults. PA was assessed using the International Physical Activity Questionnaire (IPAQ). RESULTS:Mean age was 41.4 yea...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2011.03.009
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Although the disease consequences of cigarette smoking are well documented, smoking may also be associated with increased risk of injury. Our purpose is to provide an overview of this potential association. METHODS:We conducted a literature review. RESULTS:Cigarettes are the leading cause of death from fir...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1006/pmed.1994.1070
更新日期：1994-07-01 00:00:00
abstract：:Implementing comprehensive school health programs presents one of our nation's key challenges for the 1990s and beyond. Whether we are talking about Goals 2000 or Healthy People 2000, we will meet the challenge only through the combined efforts of the education and health sectors working as partners at the national, s...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1993.1041
更新日期：1993-07-01 00:00:00
abstract：:Some cancer survivors report spending 20% of their annual income on medical care. Undue financial burden that patients face related to the cost of care is referred to as financial hardship, which may be more prevalent among rural cancer survivors. This study examined contrasts in financial hardship among 1419 rural an...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2019.105881
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:We estimated uptake of seasonal and 2009 influenza A(H1N1) vaccine among U.S. adults and assessed their perceptions of the seriousness of both types of influenza and corresponding attitudes toward vaccination during the 2009-2010 influenza season. We further documented how vaccine uptake and attitudes varied ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2010.05.008
更新日期：2010-08-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：:The prevalence of eight adverse lifestyle risk factors which are linked to increased morbidity and mortality was determined. Smoking, excess alcohol use, obesity, lack of exercise, lack of seatbelt use, use of hazardous transportation vehicles, and inadequate rest were studied. A random sample of 147 patients from a p...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(90)90051-k
更新日期：1990-09-01 00:00:00
abstract：:Although cigarette and smokeless tobacco use are recognized as major problems among school-age youth, few nationwide or statewide data exist on the prevalence and patterns of use. To determine the patterns of tobacco use among children and adolescents in Missouri, self-report information was obtained from a representa...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(90)90018-f
更新日期：1990-03-01 00:00:00
