Alterations in pulmonary mechanics after transfusion in anemic preterm infants.

abstract：OBJECTIVE:Supplementation with tetrahydrobiopterin, a nitric oxide synthase cofactor, may reduce microvascular endothelial dysfunction in severe sepsis. We studied whether tetrahydrobiopterin administration exerts beneficial effects in an ovine septic shock model. DESIGN:Randomized animal study. SETTING:University ho...

journal_title：Critical care medicine

authors： He X,Su F,Velissaris D,Salgado DR,de Souza Barros D,Lorent S,Taccone FS,Vincent JL,De Backer D

更新日期：2012-10-01 00:00:00

abstract：:The authors determined the correction factor (Ct) for three sizes of commonly available central venous catheters. These catheters are used as the injectate catheter when a 2.5 Fr transthoracic thermistor is used to determine cardiac output by thermodilution. The valves for Ct were highly reproducible. These determinat...

journal_title：Critical care medicine

authors： Baskoff JD,Maruschak GF

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:There is limited evidence supporting the widespread use of α2 agonists (clonidine and dexmedetomidine) in pediatric critical care sedation. This study sought to test the association between the use of α2 agonists and enhanced sedation. DESIGN:A retrospective observational cohort study was conducted. Noninfe...

journal_title：Critical care medicine

authors： Hayden JC,Doherty DR,Dawkins I,Leacy FP,Healy M,Breatnach CV,Cousins G,Gallagher PJ

更新日期：2019-07-01 00:00:00

abstract：:Thromboembolic disease ranks among the most dangerous and common complication in the postoperative or post-traumatic patient. As previously mentioned, the incidence is increasing and fatalities from this complication have also risen substantially. The pathogenesis of thromboembolic disease and the predictability of it...

journal_title：Critical care medicine

authors： Evarts CM

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVE:To determine whether mortality rates among intensive care unit (ICU) patients differ according to the time of ICU admission, we compared the death rates for patients admitted during weekday day shifts and off hours (from 6:30 pm to 8:29 am the next day for night shifts, from Saturday 1:00 pm to Monday 8:29 am...

journal_title：Critical care medicine

authors： Luyt CE,Combes A,Aegerter P,Guidet B,Trouillet JL,Gibert C,Chastre J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Develop a scoring system that can assess the management of septic shock by individuals and teams. DESIGN:Retrospective review of videotapes of critical care house staff managing a standardized simulation of septic shock. SETTING:Academic medical center; videotapes were made in a recreated intensive care uni...

journal_title：Critical care medicine

authors： Ottestad E,Boulet JR,Lighthall GK

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVES:Although the mortality of severe sepsis is easily quantified, the actual cause and timing of death from severe sepsis are less defined. We used the INDEPTH (International Integrated Database for the Evaluation of Severe Sepsis and Drotrecogin alfa activated) database to investigate the reported cause of deat...

journal_title：Critical care medicine

authors： Vincent JL,Nelson DR,Williams MD

更新日期：2011-05-01 00:00:00

abstract：:In the pathogenesis of sepsis, inflammation and coagulation play a pivotal role. Increasing evidence points to an extensive cross-talk between these two systems, whereby inflammation leads to activation of coagulation, and coagulation also considerably affects inflammatory activity. Molecular pathways that contribute ...

journal_title：Critical care medicine

authors： Levi M,van der Poll T

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To characterize the endothelium-dependent and endothelium-independent components of abnormal pulmonary vascular tone in canine oleic acid lung injury. DESIGN:Prospective, interventional study. SETTING:University laboratory. SUBJECTS:Twenty anesthetized mongrel dogs. INTERVENTIONS:Right heart catheterizati...

journal_title：Critical care medicine

authors： Kafi SA,Scillia P,Mélot C,Gevenois PA,Pagnamenta A,Naeije R

更新日期：2002-07-01 00:00:00

abstract：:Pulmonary artery wedge pressure (PAWP) will only reflect left atrial pressure (LAP) if continuity of fluid exists from the catheter tip to the left atrium. Either increased airway pressure or decreased hydrostatic pressure may lead to discontinuity of the fluid column and midinterpretation of PAWP. Simultaneous measur...

journal_title：Critical care medicine

authors： Kane PB,Askanazi J,Neville JF Jr,Mon RL,Hanson EL,Webb WR

更新日期：1978-01-01 00:00:00

abstract：:A polarographic conjunctival oxygen sensor was used to measure oxygen tension in a tissue bed supplied by the internal carotid artery. The shared vascular source of the conjunctiva and brain suggests that conjunctival PO2 monitoring may provide an index of cerebral perfusion. We studied the effects of hyperventilation...

journal_title：Critical care medicine

authors： Nisam M,Albertson TE,Panacek E,Rutherford W,Fisher CJ Jr

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated the therapeutic effectiveness and pharmacologic mechanisms of hyperbaric oxygen therapy (HBOT) in the treatment of a systemic shock state. To elucidate the in vivo role of HBOT during sepsis, we evaluated the effects of HBOT on intestinal mucosal injury and bacterial transloca...

journal_title：Critical care medicine

authors： Sakoda M,Ueno S,Kihara K,Arikawa K,Dogomori H,Nuruki K,Takao S,Aikou T

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Sepsis is life-threatening organ dysfunction due to dysregulated host responses to infection. Current knowledge of human B-cell alterations in sepsis is sparse. We tested the hypothesis that B-cell loss in sepsis involves distinct subpopulations of B cells and investigated mechanisms of B-cell depletion. DES...

journal_title：Critical care medicine

authors： Shankar-Hari M,Fear D,Lavender P,Mare T,Beale R,Swanson C,Singer M,Spencer J

更新日期：2017-05-01 00:00:00

abstract：:A difference between potassium concentrations in arterial plasma and venous serum was evaluated. The difference was 0.5 mM/litre, with a range of 0.1 to 1.1 mM/liter. Multiple factors operating primarily upon the venous sample are responsible for this difference. The value for arterial plasma potassium is stable and p...

journal_title：Critical care medicine

authors： Ward CF,Arkin DB,Benumof JL,Saidman LJ

更新日期：1978-09-01 00:00:00

abstract：OBJECTIVES:Neurologic damage following cardiac arrest remains a major burden for modern resuscitation medicine. Cardiopulmonary resuscitation with extracorporeal circulatory support holds the potential to reduce morbidity and mortality. Furthermore, the endogenous gasotransmitter carbon monoxide attracts attention in r...

journal_title：Critical care medicine

authors： Wollborn J,Steiger C,Doostkam S,Schallner N,Schroeter N,Kari FA,Meinel L,Buerkle H,Schick MA,Goebel U

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:Acute hemolysis is associated with organ damage, inflammation, and impaired vascular function. Stimulation of the cholecystokinin-1 receptor-dependent vagal anti-inflammatory reflex with lipid-rich enteral nutrition was demonstrated to prevent tissue damage and attenuate inflammation. This study investigates...

journal_title：Critical care medicine

authors： de Haan JJ,Windsant IV,Lubbers T,Hanssen SJ,Hadfoune M,Prinzen FW,Greve JW,Buurman WA

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the occurrence of complications and patient deteriorations during the air and ground transportation of intubated pediatric patients, performed by a nonphysician-based team under the direction of an intensive care attending physician or fellow. DESIGN:Retrospective chart review. SETTING:A 600-bed...

journal_title：Critical care medicine

authors： Beyer AJ 3rd,Land G,Zaritsky A

更新日期：1992-07-01 00:00:00

abstract：:Over a 2-year period, 14 viable ventilator-dependent patients were transferred from the Medical Intensive Care Unit (MICU) to a general ward floor for nutritional support after failing to wean from mechanical ventilation (MV) while in the MICU. These patients were retrospectively grouped based on their ultimate abilit...

journal_title：Critical care medicine

authors： Larca L,Greenbaum DM

更新日期：1982-05-01 00:00:00

abstract：INTRODUCTION:The difficult airway is a common problem in adult critical care patients. However, the challenge is not just the establishment of a safe airway, but also maintaining that safety over days, weeks, or longer. AIMS:This review considers the management of the difficult airway in the adult critical care enviro...

journal_title：Critical care medicine

authors： Lavery GG,McCloskey BV

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND METHODS:Twelve adult male albino rabbits were assigned alternately to normotensive and hypotensive groups to assess the effect of hypovolemic shock on spontaneous correction of dilutional coagulopathy. All animals underwent dilutional exchange transfusion with 200 mL of rabbit RBCs and 5% human albumin. ...

journal_title：Critical care medicine

authors： Hewson JR,Prodger D,Roberts RS,Davis C,Fuller HD,Gregor P,Thomas EJ,Shragge BW,Russett J,Neame PB

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:To study the epidemiology, style of management, and outcome of intensive care patients with acute renal failure requiring replacement therapy in Australia. DESIGN:Prospective epidemiologic study. SETTING:Australian adult intensive care units providing acute renal replacement therapy. PATIENTS:Adult intensi...

journal_title：Critical care medicine

authors： Silvester W,Bellomo R,Cole L

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:This report examines the frequency, type, and prognostic factors of medical (nonneurologic) complications after subarachnoid hemorrhage in a large, prospective study. The influences of contemporary neurosurgical, neurological, and critical care practice on mortality and morbidity rates after aneurysmal subar...

journal_title：Critical care medicine

authors： Solenski NJ,Haley EC Jr,Kassell NF,Kongable G,Germanson T,Truskowski L,Torner JC

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVES:To assess trends in the use of extracorporeal membrane oxygenation for poisoning in the United States. DESIGN:Retrospective cohort study. SETTING:The National Poison Data System, the databased owned and managed by the American Association of Poison Control Centers, the organization that supports and accred...

journal_title：Critical care medicine

authors： Cole JB,Olives TD,Ulici A,Litell JM,Bangh SA,Arens AM,Puskarich MA,Prekker ME

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:The main objective of the study was to determine the prevalence of venous thromboembolism events in patients infected with severe acute respiratory syndrome coronavirus 2 requiring venovenous extracorporeal membrane oxygenation. The secondary objective was to compare venous thromboembolism events and coagula...

journal_title：Critical care medicine

authors： Parzy G,Daviet F,Puech B,Sylvestre A,Guervilly C,Porto A,Hraiech S,Chaumoitre K,Papazian L,Forel JM

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:End-of-life practices vary worldwide. The objective was to demonstrate that there is no clear-cut distinction between treatments administered to relieve pain and suffering and those intended to shorten the dying process. DESIGN:Secondary analysis of a prospective, observational study. SETTING:Thirty-seven i...

journal_title：Critical care medicine

authors： Sprung CL,Ledoux D,Bulow HH,Lippert A,Wennberg E,Baras M,Ricou B,Sjokvist P,Wallis C,Maia P,Thijs LG,Solsona Duran J,ETHICUS Study Group.

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Despite the universal proliferation of emergency medical services programs throughout the United States since 1970, only a few have ever documented a valid lifesaving effect, particularly in large, urban centers. The purpose of this study was to demonstrate the effect of specialized physician supervision on ...

journal_title：Critical care medicine

authors： Pepe PE,Mattox KL,Duke JH,Fisher PB,Prentice FD

更新日期：1993-09-01 00:00:00

abstract：:Utilizing a well-established porcine model of cardiac arrest, we found that end-tidal CO2 concentration (ETCO2) strikingly decreased to approximately 24% of control levels, immediately after cardiac arrest and before precordial compression. During precordial compression, ETCO2 progressively increased to 46% of control...

journal_title：Critical care medicine

authors： Trevino RP,Bisera J,Weil MH,Rackow EC,Grundler WG

更新日期：1985-11-01 00:00:00

abstract：:A portable video image-processor unit used to evaluate bedside digital subtraction angiography yields sufficient information on the major arterial vessels and the heart, using standard x-ray equipment at fluoroscopic energy levels. This unit should contribute to the evaluation of the critically ill patient in the ICU....

journal_title：Critical care medicine

authors： Janssen JH,Ackermans J,Tijdens F,Verstraelen B,de Zwaan C,Bär F,Brugada P

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between sublingual and intestinal mucosal microcirculatory perfusion. DESIGN:Observational, experimental study. SETTING:University-affiliated large animal laboratory. SUBJECTS:Ten fasted, anesthetized, mechanically ventilated, male pigs randomized to a sham group (n = 3) or to...

journal_title：Critical care medicine

authors： Verdant CL,De Backer D,Bruhn A,Clausi CM,Su F,Wang Z,Rodriguez H,Pries AR,Vincent JL

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:Cardiovascular dysfunction occurs in the majority of asphyxiated neonates and has been suggested to be a major cause of neonatal morbidity and mortality. We previously demonstrated that cyclosporine A treatment during resuscitation can significantly improve cardiovascular performance in asphyxiated newborn p...

journal_title：Critical care medicine

authors： Gill RS,Lee TF,Manouchehri N,Liu JQ,Lopaschuk G,Bigam DL,Cheung PY

更新日期：2013-04-01 00:00:00