Abstract：
:This article provides a comprehensive review of the outcomes of polypharmacy in nursing homes. Our review had some limitations. First, we only included studies beginning in 1990, and significant earlier studies are not included. Only English language articles were included. We only researched studies from MEDLINE, and may have missed studies based on our search terms and search tools. There are many definitions of polypharmacy in the literature, including number of medications or inappropriate medications. In this review, we defined polypharmacy as a high number of medications, but not inappropriate medications. It was not surprising that polypharmacy was consistently associated with an increased number of potentially inappropriate drugs. The majority of studies were viewed showed that polypharmacy was associated with increased ADEs, increased DDIs, and increased hospitalizations. We were surprised that polypharmacy was not consistently linked with falls, fractures, and mortality. For the mortality studies, it has been postulated that perhaps some patients receiving 10 or more medications may have been moribund or receiving end-of-life or hospice care. It is possible that the number of medications is not as important as the number of potentially in appropriate drugs. There need to be more studies on these outcomes, using different definitions of polypharmacy. Polypharmacy was associated with increased costs. The drug-related morbidity and mortality, including those resulting from inappropriate medications and increased staff time, led to increased costs. Use of consultant pharmacists has been shown to decrease polypharmacy costs.
journal_name
Clin Geriatr Medjournal_title
Clinics in geriatric medicineauthors
Tamura BK,Bell CL,Inaba M,Masaki KHdoi
10.1016/j.cger.2012.01.005subject
Has Abstractpub_date
2012-05-01 00:00:00pages
217-36issue
2eissn
0749-0690issn
1879-8853pii
S0749-0690(12)00006-7journal_volume
28pub_type
杂志文章,评审abstract：:Hypoglycemia is a serious problem in older patients with diabetes mellitus. This chapter discusses risk factors associated with hypoglycemia and approaches to mitigation of the risk for hypoglycemia. Specific considerations include selection of glucose lowering agents, comorbid conditions and the implications of decli...
journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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journal_title：Clinics in geriatric medicine
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journal_title：Clinics in geriatric medicine
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abstract：:Bone is a complex organ which contains an organic matrix which serves as scaffolding, includes mineral as calcium distributed in a pattern providing structure and serves as an ion reservoir for the body. Throughout life it dynamically changes in response to changes in activity, body mass, and weight bearing. It is imp...
journal_title：Clinics in geriatric medicine
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abstract：:Approximately 35% to 37% of older emergency department (ED) patients will have delirium or dementia, which can negatively affect safe and appropriate clinical care. This article describes the epidemiology of delirium and dementia in the ED and how it affects clinical care and patient outcomes. Screening for delirium a...
journal_title：Clinics in geriatric medicine
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journal_title：Clinics in geriatric medicine
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doi：
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journal_title：Clinics in geriatric medicine
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1989-02-01 00:00:00
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1990-08-01 00:00:00
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1988-08-01 00:00:00
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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更新日期：2014-05-01 00:00:00
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：10.1016/s0749-0690(05)70021-5
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
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journal_title：Clinics in geriatric medicine
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
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journal_title：Clinics in geriatric medicine
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1998-05-01 00:00:00
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journal_title：Clinics in geriatric medicine
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abstract：:An understanding of the causes, nature, and course of intellectual impairment in Parkinson's disease (PD) is essential for the correct development of therapy. This article reviews the causes of the dementia of PD, its primary clinical and pathological features, and its course. ...
journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1988-11-01 00:00:00
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journal_title：Clinics in geriatric medicine
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journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：
更新日期：1993-02-01 00:00:00
abstract：:Postprandial hypotension is a prevalent condition in the elderly population and seems to be more common in frail elderly individuals who may be more susceptible to complications such as syncope and falls. Diagnosis is relatively easy and may be reversible in many cases. The epidemiology and pathophysiology of postpran...
journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：10.1016/s0749-0690(02)00012-5
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abstract：:Malignant neoplasms of the geriatric skeleton are either primary or metastatic in nature. The vast majority are metastatic to the skeleton from carcinomas. Rarely, a primary skeletal malignancy, usually a chondrosarcoma or a malignant fibrous histiocytoma, develops in the geriatric patient. This article discusses the ...
journal_title：Clinics in geriatric medicine
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Normal aging is associated with a multitude of changes in the cardiovascular system, including decreased compliance of blood vessels, mild concentric left ventricular hypertrophy, an increased contribution of atrial contraction to left ventricular filling, and a higher incidence of many cardiac arrhythmias, both brady...
journal_title：Clinics in geriatric medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cger.2012.07.003
更新日期：2012-11-01 00:00:00
