当前位置： SCI文献检索 > SURGERY期刊下所有文献 > Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: a prospective randomized controlled trial.

Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: a prospective randomized controlled trial.

Abstract：

BACKGROUND:The clinical value of synbiotics in patients undergoing esophagectomy remains unclear. This study investigated the effects of synbiotics on intestinal microflora and surgical outcomes in a clinical setting. METHODS:We studied 70 patients with esophageal cancer who were scheduled to undergo esophagectomy. They were randomly allocated to 2 groups: 1 group received synbiotics before and after surgery, and the other did not. Fecal microflora and organic acid concentrations were determined. Postoperative infections, abdominal symptoms, and duration of systemic inflammatory response syndrome (SIRS) were recorded. RESULTS:Of the patients, 64 completed the trial (synbiotics, 30; control, 34). The counts of beneficial bacteria and harmful bacteria in the group given synbiotics were significantly larger and smaller, respectively, than those in the control group on postoperative day (POD) 7. The concentrations of total organic acid and acetic acid were higher in the synbiotics group than in the control group (P < .01), and the intestinal pH in the synbiotics group was lower than that in the control (P < .05) on POD 7. The rate of infections was 10% in the synbiotics group and 29.4% in the control group (P = .0676). The duration of SIRS in the synbiotics group was shorter than in the control group (P = .0057). The incidence of interruption or reduction of enteral nutrition by abdominal symptoms was 6.7% in the synbiotics group and 29.4% in the control group (P = .0259). CONCLUSION:Perioperative administration of synbiotics in patients with esophagectomy is useful because they suppress excessive inflammatory response and relieve uncomfortable abdominal symptoms through the adjustment of the intestinal microfloral environment.

journal_name

Surgery

journal_title

Surgery

authors

Tanaka K,Yano M,Motoori M,Kishi K,Miyashiro I,Ohue M,Ohigashi H,Asahara T,Nomoto K,Ishikawa O

doi

10.1016/j.surg.2012.02.021

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

832-42

issue

5

eissn

0039-6060

issn

1532-7361

pii

S0039-6060(12)00096-7

journal_volume

152

pub_type

杂志文章,随机对照试验

相关文献

SURGERY文献大全
  • The importance of different calorie sources in the intravenous nutrition of infants and children.

    abstract：:The intravenous infusion of amino acid and carbohydrate solutions is a well-established technique for nutritional support of the pediatric surgical patient. By using peripheral veins for total parenteral nutrition (TPN), weight gain can be achieved and the complications of central venous catheters avoided. Over a 2-ye...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Benner JW,Coran AG,Weintraub WH,Wesley JR

    更新日期：1979-09-01 00:00:00

  • A comparative cross-sectional study of personality traits in internists and surgeons.

    abstract：BACKGROUND:A stereotype of surgeons' personality persists in the general public and among health-care professionals. Only a few studies have attempted to describe this "surgical personality" in detail. The aim of this study was to investigate the personality traits of surgeons compared with internists and to prove the ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2010.03.001

    authors： Warschkow R,Steffen T,Spillmann M,Kolb W,Lange J,Tarantino I

    更新日期：2010-11-01 00:00:00

  • Influence of surgical margin on type of recurrence after liver resection for colorectal metastases: a single-center experience.

    abstract：BACKGROUND:Hepatectomy for colorectal liver metastases (CRLM) may offer good long-term survival. The impact of the tumor-free surgical margin on long-term results remains controversial, and we have assessed this component in 185 patients. METHODS:Between 1992 and 2005, 185 patients underwent primary hepatectomy with c...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2007.09.038

    authors： Nuzzo G,Giuliante F,Ardito F,Vellone M,Giovannini I,Federico B,Vecchio FM

    更新日期：2008-03-01 00:00:00

  • Predictors of serious morbidity and mortality after endovascular repair of aortoiliac lesions.

    abstract：BACKGROUND:Endovascular approaches to aortoiliac disease are becoming increasingly frequent due to decreases in recovery time, bleeding, and discomfort. Despite this trend, little is known about the predictors of complications. This study was designed to identify risk factors for major 30-day morbidity and mortality af...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2018.04.028

    authors： Thomas AT,Leitman IM

    更新日期：2018-08-01 00:00:00

  • Pretreatment of renal allograft recipients with azathioprine and donor-specific blood products.

    abstract：:Improvement of renal allograft survival by induction of immunologic unresponsiveness was attempted in 24 patients by the pretransplant administration of donor-specific whole blood or buffy coat under continuous azathioprine immunosuppression. All patients and their donors had one or two disparate HLA haplotypes. Cross...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Anderson CB,Sicard GA,Etheredge EE

    更新日期：1982-08-01 00:00:00

  • Prognostic factors for poor survival after repeat hepatectomy in patients with colorectal liver metastases.

    abstract：BACKGROUND:The recurrence rate for colorectal liver metastases after repeat hepatic resection is high, and selection criteria for repeat hepatectomy are still controversial. METHODS:Clinical data of patients undergoing repeat hepatectomy for metastatic colon cancer were reviewed retrospectively and compared with those...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1067/msy.2003.151

    authors： Takahashi S,Inoue K,Konishi M,Nakagouri T,Kinoshita T

    更新日期：2003-06-01 00:00:00

  • Cervical spine fracture patterns mandating screening to rule out blunt cerebrovascular injury.

    abstract：BACKGROUND:Aggressive screening for blunt cerebrovascular injury (BCVI) and prompt anticoagulation for documented injuries has resulted in a significant reduction in ischemic neurologic events. An association between vertebral artery injuries (VAIs) and specific cervical spine fracture patterns has been suggested; howe...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2006.04.005

    authors： Cothren CC,Moore EE,Ray CE Jr,Johnson JL,Moore JB,Burch JM

    更新日期：2007-01-01 00:00:00

  • Surgical lesions of the colon in the hemolytic uremic syndrome.

    abstract：:Hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and acute renal failure, usually in children under 10 years of age. Gastrointestinal symptoms, including abdominal pain and bloody diarrhea, frequently precede the onset of renal failure. It has not been generally appreciated that ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Van Stiegmann G,Lilly JR

    更新日期：1979-03-01 00:00:00

  • The relative value of carotid noninvasive testing as determined by receiver operator characteristic curves.

    abstract：:To determine the relative value of carotid phonoangiography (CPA), oculoplethysmography-Kartchner (OPG-K), and Doppler ultrasonic arteriography (UA), 90 vessels undergoing carotid endarterectomy were prospectively examined. By analyzing the data on receiver operator characteristic curves, the dynamic relationship betw...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： O'Donnell TF Jr,Pauker SG,Callow AD,Kelly JJ,McBride KJ,Korwin S

    更新日期：1980-01-01 00:00:00

  • Histocompatibility and liver transplantation.

    abstract：BACKGROUND:The role of histocompatibility between donor and recipient in liver transplant rejection is unclear because of a paucity of data. The influence of human leukocyte antigen (HLA) type on immunologic graft loss was examined for primary liver transplantations performed at this center. METHODS:Immunologic graft ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Knechtle SJ,Kalayolu M,D'Alessandro AM,Mason B,Pirsch JD,Sollinger HW,Steen DC,Belzer FO

    更新日期：1993-10-01 00:00:00

  • A telephone-based surgical transitional care program with improved patient satisfaction scores and fiscal neutrality.

    abstract：BACKGROUND:Limited data exist regarding the downstream effects of surgical transitional care programs. We explored the impact of such programs on patient satisfaction and fiscal metrics. METHODS:A telephone-based surgical transitional care program enrolled patients undergoing complex abdominal surgery between 2015 to ...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2020.09.015

    authors： Schreiter NA,Fisher A,Barrett JR,Acher A,Sell L,Edwards D,Leverson G,Joachim A,Weber SM,Abbott DE

    更新日期：2021-02-01 00:00:00

  • Operative outcome of colon interposition in the treatment of esophageal cancer: a 20-year experience.

    abstract：BACKGROUND:In patients with esophageal cancer and a history of gastric surgery, colonic interposition is the treatment of choice. Our aim was to review our experience with this technique and to identify possible predictors of the clinical outcome. METHODS:Between 1986 and 2006, 43 patients underwent esophageal reconst...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2009.10.045

    authors： Klink CD,Binnebösel M,Schneider M,Ophoff K,Schumpelick V,Jansen M

    更新日期：2010-04-01 00:00:00

  • Quantitative comparison of operative skill using 2- and 3-dimensional monitors during laparoscopic phantom tasks.

    abstract：BACKGROUND:The recent development of stereoscopic images using 3-dimensional monitors is expected to improve techniques for laparoscopic operation. Several studies have reported technical advantages in using 3-dimensional monitors with regard to operative accuracy and working speed, but there are few reports that analy...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2016.08.060

    authors： Nishi M,Kanaji S,Otake Y,Harada H,Yamamoto M,Oshikiri T,Nakamura T,Suzuki S,Suzuki Y,Hiasa Y,Sato Y,Kakeji Y

    更新日期：2017-05-01 00:00:00

  • Regional oral tolerance in transgenic 2C mice.

    abstract：BACKGROUND:Antigen injected subcutaneously (SQ) results in a strong systemic immune response, whereas antigen infused orally or by the portal vein tends to induce tolerance. Nontransgenic C57BL/6J (H-2(b)), or B6, mice and transgenic 2C mice (that express a cytotoxic T cell receptor against major histocompatibility com...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2005.05.010

    authors： Margenthaler JA,Flye MW

    更新日期：2005-08-01 00:00:00

  • The impact of in-hospital complications on the long-term functional outcome of trauma patients: A multicenter study.

    abstract：BACKGROUND:The long-term consequences of in-hospital complications remain largely unknown. We sought to study the effect of complications on the long-term functional outcome of trauma patients. METHODS:Patients with an Injury Severity Score ≥ 9 admitted to 3, level I trauma centers between 2015 and 2017 were contacted...

    journal_title：Surgery

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.surg.2019.04.026

    authors： Lee JM,Herrera-Escobar J,Apoj M,Al Rafai SS,Han K,Nehra D,Salim A,Brasel K,Kasotakis G,Velmahos G,Haider A,Kaafarani HMA

    更新日期：2019-09-01 00:00:00

  • Hepatic insufficiency after portacaval shunting is prevented by prior intraportal pancreatic islet autotransplantation.

    abstract：:The extrahepatic diversion of essential splanchnic hepatotrophic factors may cause the liver atrophy and insufficiency that follows portacaval shunting. To investigate this, control dogs with end-to-side portacaval shunts (control-PCS, n = 6) were compared with dogs shunted 1 month after intraportal pancreatic islet a...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Callery MP,Ricordi C,Scharp DW,Kamei T,Swanson CJ,Lacy PE,Flye MW

    更新日期：1989-08-01 00:00:00

  • Development of a transplantable model of pancreatic duct adenocarcinoma.

    abstract：:We report here the first development of a continuous cell line in tissue culture of an animal pancreatic duct adenocarcinoma that is histologically similar to human pancreatic duct adenocarcinoma. A primary pancreatic duct adenocarcinoma, induced in a male Syrian golden hamster after 23 weeks of weekly subcutaneous in...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Townsend CM Jr,Franklin RB,Gelder FB,Glass E,Thompson JC

    更新日期：1982-07-01 00:00:00

  • Transsternal operations in thyroid cancer.

    abstract：:Large thyroid carcinomas extending into the anterior mediastinum were removed from six patients by a transsternal surgical approach (partial median sternotomy). Transcervical mediastinal dissection offers obscure exposure and therefore entails the risk of the operation not being radical. The transsternal procedure was...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Niederle B,Roka R,Fritsch A

    更新日期：1985-12-01 00:00:00

  • Radiographic assessment of ground-level falls in elderly patients: Is the "PAN-SCAN" overdoing it?

    abstract：INTRODUCTION:Routine, whole-body computed tomography imaging (PAN-SCAN) has been shown to identify unexpected injuries and alter the management of patients presenting with blunt trauma. We sought to characterize the changes in practice over time and the utility of PAN-SCAN imaging in elderly patients who fall and requi...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2013.07.015

    authors： Dwyer CR,Scifres AM,Stahlfeld KR,Corcos AC,Ziembicki JA,Summers JI,Peitzman AB,Billiar TR,Sperry JL

    更新日期：2013-10-01 00:00:00

  • Heat-shock gene expression excludes hepatic acute-phase gene expression after resuscitation from hemorrhagic shock.

    abstract：BACKGROUND:To determine whether the gene expression of both acute-phase reactants (APR) and the major heat-shock protein (hsp-72) can occur simultaneously, transcriptional rates were measured during shock and resuscitation. METHODS:A nuclear runoff technique was applied to hepatic biopsy specimens obtained from pigs b...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Schoeniger LO,Reilly PM,Bulkley GB,Buchman TG

    更新日期：1992-08-01 00:00:00

  • Autologous fibrin glue as a sealant of the common bile duct.

    abstract：:Autologous fibrin glue was evaluated as a sealant of the common bile duct (CBD) with the use of experimental animal models. It proved to be highly effective. Since it is a safe product that can be easily obtained from the patient's own blood, it may find useful application in most biliary tract procedures, liver trans...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Couto J,Kroczek B,Requena R,Lerner R

    更新日期：1987-03-01 00:00:00

  • The early results of reconstruction of the femoral artery with a Gore-Tex prosthesis.

    abstract：:An analysis is presented of the results of forty-one reconstructions of the superficial femoral artery using a Gore-Tex prosthesis. There were four complications and the results, when the boundary conditions were good, were comparable to those obtained from reconstruction with autogenous vein. Most failures occurred i...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Hearn AR,Charlesworth D

    更新日期：1979-06-01 00:00:00

  • Resection of leiomyosarcoma originating in internal iliac vein and extending into heart via inferior vena cava.

    abstract：:A patient's condition was initially diagnosed as constrictive pericarditis, but an echocardiogram revealed the presence of an intracardiac tumor. The tumor was a slow-growing leiomyosarcoma that originated in the left internal iliac vein, extended into the inferior vena cava, and reached the right ventricle. This tumo...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Kaku K,Kawashima Y,Kitamura S,Nakano S,Mori T,Beppu SU,Kozuka T,Sakurai M,Katayama S,Tanizawa O,Sonoda T

    更新日期：1981-05-01 00:00:00

  • Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization.

    abstract：BACKGROUND:Determination of the genetic composition of papillary thyroid cancers may help explain differences in observed clinical behavior. Comparative genomic hybridization (CGH) is a novel molecular cytogenetic assay that allows simultaneous detection of gains, losses, and amplification of genetic information, makin...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1067/msy.2000.110847

    authors： Singh B,Lim D,Cigudosa JC,Ghossein R,Shaha AR,Poluri A,Wreesmann VB,Tuttle M,Shah JP,Rao PH

    更新日期：2000-12-01 00:00:00

  • Neural regulation of heterotopic islets of Langerhans.

    abstract：:The possibility of vagal reinnervation to intrasplenic islet grafts was examined by measuring portal insulin response to electric stimulation of the dorsal vagus nerve in autografted dogs. Grafted islets responded appropriately to an exogenous cholinergic agent given intravenously. However, no insulin secretory respon...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Kakizaki K,Basadonna G,Merrell RC

    更新日期：1986-12-01 00:00:00

  • Management of of arteriosclerotic aneurysm of the innominate artery.

    abstract：:Arteriosclerotic aneurysm of the innominate artery is an unusual lesion. A review of the literature has revealed many approaches to this problem in the past, but the mortality rate has remained significant and serious complications have been frequent. Computerized axial tomography and noninvasive cerebrovascular metho...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Schumacher PD,Wright CB

    更新日期：1979-05-01 00:00:00

  • The quality of surgical clerkships.

    abstract：:Many of the contours of a surgical clerkship can be designed, implemented, and evaluated with varying degrees of objectivity. The recently established Association for Surgical Education and its expanding membership have performed in an excellent fashion in addressing the objectives, content, process, and evaluation of...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Holden WD

    更新日期：1985-06-01 00:00:00

  • The role of operative intervention in management of congenital extrahepatic portosystemic shunt.

    abstract：BACKGROUND AND AIMS:Congenital extrahepatic portosystemic shunt (CEPS) is a rare venous malformation in which mesenteric venous blood drains directly into the systemic circulation. It is still a matter of debate whether conservative or operative strategies should be used to treat symptomatic CEPS. The aim of this study...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：10.1016/j.surg.2011.07.035

    authors： Sanada Y,Urahashi T,Ihara Y,Wakiya T,Okada N,Yamada N,Egami S,Hishikawa S,Kawano Y,Ushijima K,Otomo S,Sakamoto K,Nakata M,Yasuda Y,Mizuta K

    更新日期：2012-03-01 00:00:00

  • Computerized intravenous arteriography: a technique for visualizing the peripheral vascular system.

    abstract：:A unique method of computerized fluoroscopic enhancement allows direct visualization of the entire vascular system by intravenous injection of standard contrast agents, thereby avoiding the need for arterial puncture or hospitalization. This technique has been used to satisfactorily visualize the intra- and extracrani...

    journal_title：Surgery

    pub_type： 杂志文章

    doi：

    authors： Turnipseed WD,Crummy AB,Strother C,Sackett J,Ergun D,Shaw C,Kruger R,Mistretta C,Lieberman R,Belzer FO

    更新日期：1981-01-01 00:00:00

  • Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy.

    abstract：BACKGROUND:In primary hyperparathyroidism, successful parathyroidectomy leads to improved bone mineral density in the majority of cases. Our aim was to further explore the relationship between hypercalciuria, kidney function, and bone recovery after parathyroidectomy. METHODS:Bone mineral density, estimated glomerular...

    journal_title：Surgery

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.surg.2017.02.017

    authors： Nilsson IL,Norenstedt S,Zedenius J,Pernow Y,Bränström R

    更新日期：2017-08-01 00:00:00