The impact of in-hospital complications on the long-term functional outcome of trauma patients: A multicenter study.

Abstract:

BACKGROUND:The long-term consequences of in-hospital complications remain largely unknown. We sought to study the effect of complications on the long-term functional outcome of trauma patients. METHODS:Patients with an Injury Severity Score ≥ 9 admitted to 3, level I trauma centers between 2015 and 2017 were contacted 6 to 12 months postinjury and administered a validated trauma quality-of-life survey, assessing for the presence of any functional limitation. Functional limitation was defined as the inability to perform independently one or more activities of daily living (eg, driving, walking on flat surfaces/upstairs, dressing). Medical records and the trauma registry were reviewed systematically for all patient and injury variables. The occurrence of predefined in-hospital complications (eg, pneumonia, surgical site infection) was recorded. The impact of in-hospital complications on functional limitation was assessed using multivariate logistic regression models. RESULTS:Of 1,709 patients, 1,022 completed the study. The mean age was 58 y, 56% were male, 94% had blunt trauma, and the mean Injury Severity Score was 15. A total of 168 patients (16.4%) had a minimum of 1 in-hospital complication and reported significantly more functional limitations in most activities of daily living at 6 to 12 months, compared with those without complications. In multivariable analyses adjusting for confounders, the occurrence of complications was associated with a greater likelihood of functional limitation 6 to 12 months postinjury (odds ratio = 1.82, 95% confidence interval 1.22-2.69, P = .003). CONCLUSION:Trauma patients with in-hospital complications have a worse long-term functional outcome. In addition to prevention of primary complications, more rehabilitation resources should be made available to trauma patients who survive complications.

journal_name

Surgery

journal_title

Surgery

authors

Lee JM,Herrera-Escobar J,Apoj M,Al Rafai SS,Han K,Nehra D,Salim A,Brasel K,Kasotakis G,Velmahos G,Haider A,Kaafarani HMA

doi

10.1016/j.surg.2019.04.026

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

398-402

issue

3

eissn

0039-6060

issn

1532-7361

pii

S0039-6060(19)30208-9

journal_volume

166

pub_type

杂志文章,多中心研究

相关文献

SURGERY文献大全
  • Splanchnic and total body oxygen consumption differences in septic and injured patients.

    abstract::The splanchnic and total body oxygen exchange and flow dynamics for injured patients (n = 7) and patients with sepsis and stable vital signs (n = 12) were studied. All patients were judged to be in the hyperdynamic phase of the stress response. In both patient groups 27% to 28% of the cardiac index was directed to the...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Dahn MS,Lange P,Lobdell K,Hans B,Jacobs LA,Mitchell RA

    更新日期:1987-01-01 00:00:00

  • Laparoscopic versus open adrenalectomy: another look at outcome using the Clavien classification system.

    abstract:BACKGROUND:A laparoscopic approach to adrenalectomy has become the procedure of choice for most adrenal resections. We hypothesized that laparoscopic adrenalectomy is less likely to result in intensive care unit (ICU) level complications or death than open adrenalectomy, despite baseline comorbidity mix. METHODS:Using...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2012.08.020

    authors: Eichhorn-Wharry LI,Talpos GB,Rubinfeld I

    更新日期:2012-12-01 00:00:00

  • Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress.

    abstract:BACKGROUND:Propranolol has been shown previously to restore bone marrow function and improve anemia after lung contusion/hemorrhagic shock. We hypothesized that daily clonidine administration would inhibit central sympathetic outflow and restore bone marrow function in our rodent model of lung contusion/hemorrhagic sho...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2016.08.043

    authors: Alamo IG,Kannan KB,Ramos H,Loftus TJ,Efron PA,Mohr AM

    更新日期:2017-03-01 00:00:00

  • Exenterative surgery for locally advanced rectosigmoid cancers. Is it worthwhile?

    abstract::Among 1480 patients treated for cancers of the rectosigmoid over a 30-year period, 24 patients underwent total pelvic exenteration. These patients, 13 men and 11 women, had a median age of 64 years. Pathologic staging revealed 15 Dukes' B and nine Dukes' C lesions. For 17 patients, this operation was the only form of ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Lopez MJ,Kraybill WG,Downey RS,Johnston WD,Bricker EM

    更新日期:1987-10-01 00:00:00

  • Pelvic ring fractures: implications of vehicle design, crash type, and occupant characteristics.

    abstract:BACKGROUND:Pelvic ring fractures (PRFs) are a major cause of morbidity and mortality in motor vehicle collisions (MVCs). Understanding the factors leading to PRFs may help improve vehicle design and safety. This study sought to determine the vehicular, crash, and occupant characteristics that contribute to PRFs. METHO...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2004.07.003

    authors: Rowe SA,Sochor MS,Staples KS,Wahl WL,Wang SC

    更新日期:2004-10-01 00:00:00

  • Symptomatic catheter-associated thrombosis in pediatric trauma patients: Choose your access wisely.

    abstract:BACKGROUND:Traumatic injury and the presence of a central venous catheter are 2 of the strongest risk factors for venous thromboembolism in children. The purpose of this study was to determine the incidence of symptomatic, catheter-associated thrombosis in critically injured children. We hypothesized that femoral venou...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2019.05.018

    authors: McLaughlin CM,Barin EN,Fenlon M,Azen C,Deakers TW,Stein JE,Bliss DW,Upperman JS,Jensen AR

    更新日期:2019-12-01 00:00:00

  • Sociologic factors are major determinants of prolonged hospital stay after abdominal aneurysm repair.

    abstract:BACKGROUND:With increasing pressure to optimize the utilization of hospital resources, it is important to identify patients who may have prolonged hospital length of stay (LOS). The purpose of this report was to identify the preoperative variables that are predictive of prolonged postoperative hospital LOS for patients...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(96)80194-2

    authors: Kalman PG,Johnston KW

    更新日期:1996-06-01 00:00:00

  • Cytoreductive hepatic surgery for neuroendocrine tumors.

    abstract::We retrospectively reviewed 37 patients who underwent hepatic resection between 1970 and 1989 to evaluate the role of cytoreductive hepatic surgery in patients with metastatic neuroendocrine tumors (carcinoid, 24; islet cell, 13). Seventeen resections were curative (no gross residual tumor); nine patients had symptoma...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: McEntee GP,Nagorney DM,Kvols LK,Moertel CG,Grant CS

    更新日期:1990-12-01 00:00:00

  • Surgery for diverticulitis is associated with high risk of in-hospital mortality and morbidity in older patients with end-stage renal disease.

    abstract:INTRODUCTION:End-stage renal disease (ESRD) is associated with poor medical outcomes. This study aimed to compare early outcomes of elective and emergency operation for diverticulitis among older adults with and without a diagnosis of ESRD. METHODS:Patients 65 years of age and older with a primary diagnosis of diverti...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2014.03.034

    authors: Moran-Atkin E,Stem M,Lidor AO

    更新日期:2014-08-01 00:00:00

  • The "July phenomenon" and the care of the severely injured patient: fact or fiction?

    abstract:BACKGROUND:The "July phenomenon," a common belief in medical academia, refers to purported errors, inefficiency, and negative outcomes during the summertime transition of the house staff. We hypothesized that care in a trauma service is consistent throughout the year and that the July phenomenon therefore is a myth. M...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2001.116670

    authors: Claridge JA,Schulman AM,Sawyer RG,Ghezel-Ayagh A,Young JS

    更新日期:2001-08-01 00:00:00

  • Heparanase-1 expression is associated with the metastatic potential of breast cancer.

    abstract:BACKGROUND:Metastasis of malignant breast cells is in part mediated through degradation of the extra-cellular matrix by proteolysis, enabling malignant cells to migrate through the surrounding stroma. Heparanase-1 (HPR1) is an endoglycosidase that specifically degrades the heparan sulfate (HS) moiety of proteoglycans, ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2002.125719

    authors: Maxhimer JB,Quiros RM,Stewart R,Dowlatshahi K,Gattuso P,Fan M,Prinz RA,Xu X

    更新日期:2002-08-01 00:00:00

  • Tertiary care centers: a strategy for fiscal survival.

    abstract:BACKGROUND:Managed care organizations use a variety of payment strategies to contract for high-end tertiary services with academic healthcare centers. We assessed the financial outcome of these strategies and attempted to identify those that maintain a balance between cost and reimbursement. METHODS:Patients admitted ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(03)00329-5

    authors: Rodriguez JL,Brill JP,Hoth JJ,Stassen NA,Franklin GA,Barbier R,Polk HC Jr

    更新日期:2003-10-01 00:00:00

  • Development of models to predict early post-transplant recurrence of hepatocellular carcinoma that also integrate the quality and characteristics of the liver graft: A national registry study in China.

    abstract:BACKGROUND:Donor characteristics and graft quality were recently reported to play an important role in the recurrence of hepatocellular carcinoma after liver transplantation. Our aim was to establish a prognostic model by using both donor and recipient variables. METHODS:Data of 1,010 adult patients (training/validati...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2018.01.022

    authors: Ling Q,Liu J,Zhuo J,Zhuang R,Huang H,He X,Xu X,Zheng S

    更新日期:2018-04-27 00:00:00

  • Social media is a necessary component of surgery practice.

    abstract::Social media is a necessary component of the practice of surgery. Each surgeon must embrace the power and potential of social media and serve as a guide or content expert for patients and other health care providers to facilitate and share responsible use of the various media available. Social media facilitates rapid ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2015.06.002

    authors: Steele SR,Arshad S,Bush R,Dasani S,Cologne K,Bleier JI,Raphaeli T,Kelz RR,Society of University Surgeons' Social and Legislative Committee.

    更新日期:2015-09-01 00:00:00

  • Mucosal melanoma of the female genitalia: a clinicopathologic study of forty-three cases at Duke University Medical Center.

    abstract:BACKGROUND:Mucosal melanoma of the female genitalia is a rare neoplasm. Only nine reports reviewing more than 40 patients have been published on this subject in the past 30 years. These lesions arise from melanocytes, which can be found within the mucosa lining the female genital tract. Surgical resection is the mainst...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: DeMatos P,Tyler D,Seigler HF

    更新日期:1998-07-01 00:00:00

  • Intraoperative radiation therapy for biliary tract carcinoma: results of a 5-year experience.

    abstract::The results of a 5-year experience with use of intraoperative radiation therapy (IORT) in the management of locally advanced bile duct carcinoma are presented. Fifteen patients received IORT doses between 5 and 20 Gy for localized disease, which was either primary and resected with microscopic residual (2 patients), p...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Busse PM,Stone MD,Sheldon TA,Chaffey JT,Cady B,McDermott WV,Bothe A Jr,Jenkins R,Steele G Jr

    更新日期:1989-06-01 00:00:00

  • Indium-111-pentetreotide scanning versus conventional imaging techniques for the localization of gastrinoma.

    abstract:BACKGROUND:The present study evaluates 111In-pentetreotide scanning as a method for detection of gastrinomas. Operative findings serve as the benchmark for comparison of the efficacy of 111In-pentetreotide versus conventional imaging studies. METHODS:Twelve patients (seven female and five male; age, 37 to 80 years) wi...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/s0039-6060(05)80121-7

    authors: Schirmer WJ,Melvin WS,Rush RM,O'Dorisio TM,Pozderac RV,Olsen JO,Ellison EC

    更新日期:1995-12-01 00:00:00

  • NIFT-P: Are they indolent tumors? Results of a multi-institutional study.

    abstract:BACKGROUND:Encapsulated follicular variant of papillary thyroid carcinoma has recently been reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features on the basis of its highly indolent behavior, as proposed by an international group of experienced thyroid pathologists. METHODS:All p...

    journal_title:Surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.surg.2018.04.089

    authors: Chereau N,Greilsamer T,Mirallié E,Sadowski SM,Pusztaszeri M,Triponez F,Baud G,Pattou F,Christou N,Mathonnet M,Brunaud L,Santucci N,Goudet P,Guérin C,Sebag F,Donatini G,Kraimps JL,Tissier F,Lussey-Lepoutre C,Leenhard

    更新日期:2019-01-01 00:00:00

  • Effect of methacholine on acid and pepsin responses to pentagastrin in cats with innervated and denervated fundic pouches.

    abstract::The effect of threshold dose of methacholine on gastric secretion stimulated by pentagastrin (PG) was studied in two groups of cats, four with Pavlov pouches (PP) and four with Heidenhain pouches (HP). In the PP group methacholine did not alter the maximal response (MR) and the dose producing half of the maximal respo...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Svensson SO,Dubrasquet M,Emas S

    更新日期:1977-11-01 00:00:00

  • Nonoperative management of blunt hepatic trauma in adults.

    abstract::Although well accepted in pediatric patients, nonoperative management of blunt hepatic trauma in adults remains controversial. From January 1981 through May 1987, 66 adults were identified with blunt hepatic trauma that had been confirmed by abdominal exploration or abdominal computed tomography (CT): 46 underwent imm...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Farnell MB,Spencer MP,Thompson E,Williams HJ Jr,Mucha P Jr,Ilstrup DM

    更新日期:1988-10-01 00:00:00

  • Evaluation of a 15-year experience with splenic injuries in a state trauma system.

    abstract:BACKGROUND:The management of splenic injuries has evolved with a greater emphasis on nonoperative management. Although several institutions have demonstrated that nonoperative management of splenic injuries can be performed with an increasing degree of success, the impact of this treatment shift on outcome for all pati...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2006.06.032

    authors: Harbrecht BG,Zenati MS,Ochoa JB,Puyana JC,Alarcon LH,Peitzman AB

    更新日期:2007-02-01 00:00:00

  • Effect of intestinal inflammation on neuronal survival and function in the dorsal motor nucleus of the vagus.

    abstract:BACKGROUND:The effects of intestinal inflammation on the central nervous system are unknown. The dorsal motor nucleus of the vagus (DMNV) integrates peripheral and central signals and sends efferent signals to the gastrointestinal system. The purpose of this study was to determine the effects of intestinal inflammation...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2008.03.042

    authors: Ammori JB,Zhang WZ,Li JY,Chai BX,Mulholland MW

    更新日期:2008-08-01 00:00:00

  • Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization.

    abstract:BACKGROUND:Determination of the genetic composition of papillary thyroid cancers may help explain differences in observed clinical behavior. Comparative genomic hybridization (CGH) is a novel molecular cytogenetic assay that allows simultaneous detection of gains, losses, and amplification of genetic information, makin...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2000.110847

    authors: Singh B,Lim D,Cigudosa JC,Ghossein R,Shaha AR,Poluri A,Wreesmann VB,Tuttle M,Shah JP,Rao PH

    更新日期:2000-12-01 00:00:00

  • Apoptosis regulating genes, bcl-2 and bax, and human telomerase reverse transcriptase messenger RNA expression in adrenal tumors: possible diagnostic and prognostic importance.

    abstract:BACKGROUND:Apoptosis-suppressing gene, bcl-2, and apoptosis-inducing gene, bax, are expressed in various tumors. Human telomerase reverse transcriptase (hTERT) expression is increased in many cancers. The purpose of this investigation was to determine whether bcl-2 or bax gene expression differs between benign and mali...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2002.128616

    authors: Kanauchi H,Wada N,Clark OH,Duh QY

    更新日期:2002-12-01 00:00:00

  • Carotid endarterectomy protects elderly patients from cognitive decline: a prospective study.

    abstract:BACKGROUND:Carotid endarterectomy (CEA) reduces the risk of stroke in selected patients with symptomatic and asymptomatic carotid disease, but its beneficial influence on cognitive performance in the elderly remains debatable. This prospective study sought to determine early and long-term neurocognitive outcomes after ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2011.06.031

    authors: Baracchini C,Mazzalai F,Gruppo M,Lorenzetti R,Ermani M,Ballotta E

    更新日期:2012-01-01 00:00:00

  • Validation of the prognostic value of lymph node ratio in patients with cutaneous melanoma: a population-based study of 8,177 cases.

    abstract:BACKGROUND:The proportion of positive among examined lymph nodes (lymph node ratio [LNR]) has been recently proposed as an useful and easy-to-calculate prognostic factor for patients with cutaneous melanoma. However, its independence from the standard prognostic system TNM has not been formally proven in a large series...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2011.02.021

    authors: Mocellin S,Pasquali S,Rossi CR,Nitti D

    更新日期:2011-07-01 00:00:00

  • Gallstone ileus associated with Crohn's disease.

    abstract::Gallstone ileus in association with Crohn's disease of the terminal ileum is a surprisingly uncommon occurrence. The diseased ileal segment may be responsible for gallstone lithogenesis as well as for luminal stenosis that prevents gallstone passage. We report only the third case of gallstone ileus in Crohn's disease ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:

    authors: Senofsky GM,Stabile BE

    更新日期:1990-07-01 00:00:00

  • Decreased blood oxygen diffusion in hypercholesterolemia.

    abstract:BACKGROUND:Improvement of angina pectoris symptoms after cholesterol lowering has raised questions as to the underlying mechanisms. METHODS:Rabbit experiment: We compared arterial blood samples from New Zealand White cholesterol-supplemented rabbits (n = 6) with nonsupplemented rabbit samples (n = 4) in a closed-loop ...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.1998.90944

    authors: Menchaca HJ,Michalek VN,Rohde TD,O'Dea TJ,Buchwald H

    更新日期:1998-10-01 00:00:00

  • Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase.

    abstract:BACKGROUND:Apoptotic cell death and c-Jun N-terminal kinase (JNK) activation occur after hepatic ischemia/reperfusion injury. In other cell types, JNK activation was shown to be required for apoptosis. This study tested the hypotheses that JNK contributes to hepatocellular apoptosis, and that inhibition of JNK activity...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1067/msy.2003.237

    authors: Marderstein EL,Bucher B,Guo Z,Feng X,Reid K,Geller DA

    更新日期:2003-08-01 00:00:00

  • Surgical research publication in a selection of research and surgical specialty journals.

    abstract:BACKGROUND:A prior study revealed a paucity of surgical research in the 5 top-rated general surgery journals for 1998. The hypothesis of the current study was that a large amount of surgical research was published in other journals. METHODS:In all, 15 research journals and 9 surgery specialty journals were reviewed fo...

    journal_title:Surgery

    pub_type: 杂志文章

    doi:10.1016/j.surg.2009.07.005

    authors: Donovan AJ,Tompkins RK

    更新日期:2010-01-01 00:00:00