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Hemodynamic effects of high versus low-osmolar contrast media for ventriculography in severe aortic stenosis.

Abstract：

:The hemodynamic effects of high- (diatrizoate meglumine/sodium) and low- (iopamidol) osmolar contrast administration for left ventriculography were compared in 15 patients with severe aortic valve stenosis. Patients were similar with respect to aortic valve gradient, aortic valve area, age, body surface area, and baseline hemodynamics as well as associated coronary disease and valvular insufficiency. Administration of diatrizoate meglumine/sodium was associated with a 22% increase in heart rate, and marked (27%) decrease in left ventricular systolic pressure, with a small (15%) increase in left ventricular end diastolic pressure. In contrast, administration of larger volumes of iopamidol was associated with only a slight (9%) increase in heart rate, a small (6%) decrease in left ventricular systolic pressure, and a smaller (6%) increase in left ventricular end diastolic pressure. In patients with severe aortic valve stenosis iopamidol may offer a safer hemodynamic profile than diatrizoate meglumine/sodium.

journal_name

Cardiovasc Intervent Radiol

journal_title

Cardiovascular and interventional radiology

authors

Lambert CR,Pepine CJ

doi

10.1007/BF02577016

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

10-3

issue

1

eissn

0174-1551

issn

1432-086X

journal_volume

11

pub_type

杂志文章

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