Distinctive flow pattern of wall shear stress and oscillatory shear index: similarity and dissimilarity in ruptured and unruptured cerebral aneurysm blebs.

Abstract:

OBJECT:The difference in the hemodynamics of wall shear stress (WSS) and oscillatory shear index (OSI) between ruptured and unruptured aneurysms is not well understood. The authors investigated the hemodynamic similarities and dissimilarities in ruptured and thin-walled unruptured aneurysm blebs. METHODS:Magnetic resonance imaging-based fluid dynamics analysis was used to calculate WSS and OSI, and hemodynamic and intraoperative findings were compared. The authors also compared ruptured and unruptured thin-walled blebs for the magnitude of WSS and OSI. RESULTS:Intraoperatively, 13 ruptured and 139 thin-walled unruptured aneurysm blebs were identified. Twelve of the ruptured (92.3%) and 124 of the unruptured blebs (89.2%) manifested low WSS and high OSI. The degree of WSS was significantly lower in ruptured (0.49 ± 0.12 Pa) than in unruptured (0.64 ± 0.15 Pa; p < 0.01) blebs. CONCLUSIONS:Ruptured and unruptured blebs shared a distinctive pattern of low WSS and high OSI. The degree of WSS at the rupture site was significantly lower than in the unruptured thin-walled blebs.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Kawaguchi T,Nishimura S,Kanamori M,Takazawa H,Omodaka S,Sato K,Maeda N,Yokoyama Y,Midorikawa H,Sasaki T,Nishijima M

doi

10.3171/2012.7.JNS111991

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

774-80

issue

4

eissn

0022-3085

issn

1933-0693

journal_volume

117

pub_type

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