Cell cycle arrest and astrocytic differentiation resulting from PTEN expression in glioma cells.

abstract：:The authors have presented 81 children with intraspinal tumors, all less than 16 years of age. The clinical features indicated that gait disturbance, pain, and sphincter disturbance are the most prominent complaints. Reflex changes, paralysis, and sensory impairment are the most frequent physical findings. Cerebrospin...

journal_title：Journal of neurosurgery

authors： DeSousa AL,Kalsbeck JE,Mealey J Jr,Campbell RL,Hockey A

更新日期：1979-10-01 00:00:00

abstract：OBJECTIVE:The optimal margin size in postoperative stereotactic radiosurgery (SRS) for brain metastases is unknown. Herein, the authors investigated the effect of SRS planning target volume (PTV) margin on local recurrence and symptomatic radiation necrosis postoperatively. METHODS:Records of patients who received pos...

journal_title：Journal of neurosurgery

authors： Jhaveri J,Chowdhary M,Zhang X,Press RH,Switchenko JM,Ferris MJ,Morgan TM,Roper J,Dhabaan A,Elder E,Eaton BR,Olson JJ,Curran WJ,Shu HG,Crocker IR,Patel KR

更新日期：2018-04-20 00:00:00

abstract：OBJECT:Nonfunctioning pituitary adenomas (NFPAs) are benign tumors of the pituitary gland that typically cause visual and/or hormonal dysfunction. Surgery is the treatment of choice, but patients remain at risk for tumor recurrence for several years afterwards. The authors evaluate the early results of surgery and the ...

journal_title：Journal of neurosurgery

authors： Losa M,Mortini P,Barzaghi R,Ribotto P,Terreni MR,Marzoli SB,Pieralli S,Giovanelli M

更新日期：2008-03-01 00:00:00

abstract：OBJECT:The aim of this study was to evaluate the usefulness and limitations of gamma surgery (GS) in the treatment of brain metastases from melanoma. METHODS:Imaging and clinical outcomes in 45 patients treated for 92 brain metastases from melanoma between October 1989 and October 1999 were retrospectively analyzed. F...

journal_title：Journal of neurosurgery

authors： Mingione V,Oliveira M,Prasad D,Steiner M,Steiner L

更新日期：2002-03-01 00:00:00

abstract：:The authors' initial experience with the endoscopic extradural supraorbital approach to the temporal pole and adjacent area is reported. Fully endoscopic surgery using the extradural space via a supraorbital keyhole was performed for tumors in or around the temporal pole, including temporal pole cavernous angioma, sph...

journal_title：Journal of neurosurgery

authors： Komatsu F,Imai M,Shigematsu H,Aoki R,Oda S,Shimoda M,Matsumae M

更新日期：2018-06-01 00:00:00

abstract：OBJECT:The extent of peritumoral brain edema (PTBE) associated with meningiomas can be highly variable. The authors studied the correlation between the development of efferent venous drainage from the tumor and the degree of PTBE that occurs in intracranial meningiomas. METHODS:Twenty-five patients with 27 intracrania...

journal_title：Journal of neurosurgery

authors： Tanaka M,Imhof HG,Schucknecht B,Kollias S,Yonekawa Y,Valavanis A

更新日期：2006-03-01 00:00:00

abstract：OBJECT:Although nucleus ventralis intermedius stimulation has been shown to be safe and efficacious in the treatment of essential tremor, there is a subset of patients who eventually lose benefit from their stimulation. Proposed causes for this phenomenon include tolerance, disease progression, and suboptimal location....

journal_title：Journal of neurosurgery

authors： Pilitsis JG,Metman LV,Toleikis JR,Hughes LE,Sani SB,Bakay RA

更新日期：2008-10-01 00:00:00

abstract：:Cerebral sinus thrombosis, although uncommon, can be lethal if not recognized and treated quickly. Systemic heparin has become the treatment standard of care; however, some patients' conditions continue to deteriorate even while taking heparin. Endovascular techniques for thrombolysis have continued to evolve. The aut...

journal_title：Journal of neurosurgery

authors： Rickert KL,Purdy PD,Welch BG

更新日期：2011-01-01 00:00:00

abstract：OBJECT:Emerging evidence supports the hypothesis that modulation of specific central neuronal systems contributes to the clinical efficacy of deep brain stimulation (DBS) and motor cortex stimulation (MCS). Real-time monitoring of the neurochemical output of targeted regions may therefore advance functional neurosurger...

journal_title：Journal of neurosurgery

authors： Bledsoe JM,Kimble CJ,Covey DP,Blaha CD,Agnesi F,Mohseni P,Whitlock S,Johnson DM,Horne A,Bennet KE,Lee KH,Garris PA

更新日期：2009-10-01 00:00:00

abstract：OBJECT:The purpose of this study was to examine patterns of diagnosis and relative survival rates in individuals in whom a primary malignant brain tumor was diagnosed between 1973 and 1997; follow-up review of these patients continued through the end of 1999. METHODS:The study population was composed of 21,493 patient...

journal_title：Journal of neurosurgery

authors： Barnholtz-Sloan JS,Sloan AE,Schwartz AG

更新日期：2003-09-01 00:00:00

abstract：OBJECT:Studies on risk factors for subarachnoid hemorrhage (SAH) show heterogeneity. For example, hypertension has been found to be a significant risk factor in some studies but not in others. The authors hypothesized that differences in the ethnicity of the populations studied could account for these findings. METHOD...

journal_title：Journal of neurosurgery

authors： Krishna V,Kim DH

更新日期：2007-09-01 00:00:00

abstract：:OBJECTIVE Glioma is the most common form of brain tumor and has high lethality. The authors of this study aimed to elucidate the efficiency of preoperative inflammatory markers, including neutrophil/lymphocyte ratio (NLR), derived NLR (dNLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR), and progno...

journal_title：Journal of neurosurgery

authors： Zheng SH,Huang JL,Chen M,Wang BL,Ou QS,Huang SY

更新日期：2018-09-01 00:00:00

abstract：:OBJECTIVE Meige syndrome is characterized by blepharospasm and varied subphenotypes of craniocervical dystonia. Current literature on pallidal surgery for Meige syndrome is limited to case reports and a few small-scale studies. The authors investigated the clinical outcomes of deep brain stimulation (DBS) of the globu...

journal_title：Journal of neurosurgery

authors： Horisawa S,Ochiai T,Goto S,Nakajima T,Takeda N,Kawamata T,Taira T

更新日期：2018-01-19 00:00:00

abstract：:Thirty-one monkeys were randomly divided into three groups to undergo baseline cerebral angiography followed by induction of subarachnoid hemorrhage by placement of autologous blood clot along the right-sided arteries of the anterior circle of Willis (Day 0). The monkeys were then given drug vehicle or one of two endo...

journal_title：Journal of neurosurgery

authors： Hino A,Weir BK,Macdonald RL,Thisted RA,Kim CJ,Johns LM

更新日期：1995-09-01 00:00:00

abstract：:In this study of 110 cranial cavities from adult cadavers, the superior sagittal sinus was found to divide into two channels. In most cases, the division was associated with a dural partition. Essentially, the variations as observed in this study could be grouped into three types: Type 1 includes those specimens in wh...

journal_title：Journal of neurosurgery

authors： Bisaria KK

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:The use of the optical contrast agent sodium fluorescein (NaFl) to guide resection of gliomas has been under investigation for decades. Although this imaging strategy assumes the agent remains confined to the vasculature except in regions of blood-brain barrier (BBB) disruption, clinical studies have reported...

journal_title：Journal of neurosurgery

authors： Folaron M,Strawbridge R,Samkoe KS,Filan C,Roberts DW,Davis SC

更新日期：2018-09-07 00:00:00

abstract：:To characterize the temporal course of radiosurgical lesions, 19 cats were irradiated in an animal linear accelerator radiosurgical device. The animals were followed clinically and, at 3.5, 6, 12, 18, 23, 29, and 63 weeks, were studied with gadolinium-enhanced magnetic resonance (MR) imaging. They were then sacrificed...

journal_title：Journal of neurosurgery

authors： Blatt DR,Friedman WA,Bova FJ,Theele DP,Mickle JP

更新日期：1994-06-01 00:00:00

abstract：OBJECT:Surgical mortality is a frequent outcome measure in studies of volume-outcome relationships, and the Agency for Healthcare Research and Quality has endorsed surgical mortality after craniotomies as an Inpatient Quality Indicator. Still, the frequency and causes of 30-day mortality after neurosurgical procedures ...

journal_title：Journal of neurosurgery

authors： Solheim O,Jakola AS,Gulati S,Johannesen TB

更新日期：2012-04-01 00:00:00

abstract：OBJECT:The aim of this study was to compare the effects of two different treatment protocols on physiological characteristics and outcome in patients with brain trauma. One protocol was primarily oriented toward reducing intracranial pressure (ICP), and the other primarily on maintaining cerebral perfusion pressure (CP...

journal_title：Journal of neurosurgery

authors： Howells T,Elf K,Jones PA,Ronne-Engström E,Piper I,Nilsson P,Andrews P,Enblad P

更新日期：2005-02-01 00:00:00

abstract：:OBJECTIVEDecompressive craniectomy is used for uncontrolled intracranial pressure in traumatic brain injury and malignant hemispheric stroke. Subcutaneous preservation of the autologous bone flap in the abdomen is a simple, portable technique but has largely been abandoned due to perceived concerns of resorption. The ...

journal_title：Journal of neurosurgery

authors： Ernst G,Qeadan F,Carlson AP

更新日期：2018-12-01 00:00:00

abstract：:Induction of hypothermia is used routinely in neurosurgical and cardiovascular operations to protect the brain from ischemic insult. However, despite a plethora of experimental evidence supporting the use of hypothermia to protect the brain from ischemia, clinical experience using deliberate hypothermia in humans has ...

journal_title：Journal of neurosurgery

authors： Sagher O,Huang DL,Webb RC

更新日期：1997-09-01 00:00:00

abstract：OBJECT:The authors performed a retrospective analysis of a consecutive series of craniopharyngiomas and their recurrences, which were managed with surgery alone. METHODS:In the past 20 years, 37 consecutive patients with craniopharyngiomas underwent surgery without adjuvant radiotherapy. During that period there was a...

journal_title：Journal of neurosurgery

authors： Minamida Y,Mikami T,Hashi K,Houkin K

更新日期：2005-08-01 00:00:00

abstract：:The authors have reviewed the clinical records of 110 patients with intracranial cavernous malformations diagnosed by histological examination and/or magnetic resonance imaging over a mean follow-up period of 4.71 years. These cases were divided, based on their presentation, into a hemorrhage group, a seizure group, a...

journal_title：Journal of neurosurgery

authors： Aiba T,Tanaka R,Koike T,Kameyama S,Takeda N,Komata T

更新日期：1995-07-01 00:00:00

abstract：:A technique of "frameless" stereotaxy that allows real-time intraoperative neurosurgical localization is described. The system is composed of four components: a hand-held probe containing two ultrasonic emitters, a microphone array that is rigidly affixed to the operating table in proximity to the surgical field, hard...

journal_title：Journal of neurosurgery

authors： Barnett GH,Kormos DW,Steiner CP,Weisenberger J

更新日期：1993-03-01 00:00:00

abstract：:The expanding use of intrathecal baclofen for spasticity has raised a concern about the treatment of overdose in these patients, since no specific baclofen antagonist is available. Since physostigmine has been reported to reverse the respiratory depression and somnolence due to opiates, the drug was tried for the trea...

journal_title：Journal of neurosurgery

authors： Müller-Schwefe G,Penn RD

更新日期：1989-08-01 00:00:00

abstract：:Forty-one patients with brain lesions underwent brain biopsy using either a computerized tomography (CT)-guided stereotactic approach or an ultrasound-guided technique. The cases were selected according to location and size of the mass lesion. Lesions 15 mm or less in diameter and those in the posterior fossa were bio...

journal_title：Journal of neurosurgery

authors： Di Lorenzo N,Esposito V,Lunardi P,Delfini R,Fortuna A,Cantore G

更新日期：1991-11-01 00:00:00

abstract：:Spinal dural lacerations can be a difficult part of spinal surgery. A dural tear can result in complications that include meningitis and pseudocyst formation. Appropriate treatment for these tears is generally suturing, using 4.0, 5.0, or 6.0 suture. For successful closure of dural lacerations, the authors have collab...

journal_title：Journal of neurosurgery

authors： Levy DI,Sonntag VK

更新日期：1994-12-01 00:00:00

abstract：OBJECT:Posterior fossa arteriovenous malformations (AVMs) are relatively uncommon and often difficult to treat. The authors present their experience with multimodality treatment of 76 posterior fossa AVMs, with an emphasis on Spetzler-Martin Grades III-V AVMs. METHODS:Seventy-six patients with posterior fossa AVMs tre...

journal_title：Journal of neurosurgery

authors： Kelly ME,Guzman R,Sinclair J,Bell-Stephens TE,Bower R,Hamilton S,Marks MP,Do HM,Chang SD,Adler JR,Levy RP,Steinberg GK

更新日期：2008-06-01 00:00:00

abstract：:The authors report on a 57-year-old woman in whom progression to brain death occurred on day 9 after aneurysmal subarachnoid hemorrhage without evidence of significant brain edema or vasospasm. Neuromonitoring demonstrated that brain death was preceded by a series of cortical spreading depolarizations that occurred in...

journal_title：Journal of neurosurgery

authors： Carlson AP,Shuttleworth CW,Major S,Lemale CL,Dreier JP,Hartings JA

更新日期：2018-12-07 00:00:00

abstract：:Gas myelography was carried out in 22 patients with acute cervical spinal cord injuries in whom oily contrast media seemed contraindicated. The authors believe this technique makes a valuable contribution to the basic decision regarding the surgical versus medical treatment of a specific patient with a cervical cord i...

journal_title：Journal of neurosurgery

authors： Rossier AB,Berney J,Rosenbaum AE,Hachen J

更新日期：1975-03-01 00:00:00