Endometrial response to endogenous hormones after pelvic irradiation for genital malignancies.


:Two cases are presented which demonstrate histologically an endometrial response to endogenous hormones after pelvic teletherapy and brachytherapy in patients who have undergone lateral ovarian transposition. Reasons for such a response are briefly discussed.


Gynecol Oncol


Gynecologic oncology


Larson JE,Whitney CW,Zaino R,Kaminski P,Podczaski E,Mortel R




Has Abstract


1990-01-01 00:00:00












  • The influence of tumor grade, distribution, and extent of carcinomatosis in minimal residual stage III epithelial ovarian cancer after optimal primary cytoreductive surgery.

    abstract::The purpose of this study was to determine the influence of tumor grade, distribution, and extent of carcinomatosis in minimal residual epithelial ovarian cancer after primary optimal cytoreductive surgery. Between 1978 and 1990, 112 patients with stage III epithelial ovarian cancer underwent primary cytoreductive sur...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Farias-Eisner R,Teng F,Oliveira M,Leuchter R,Karlan B,Lagasse LD,Berek JS

    更新日期:1994-10-01 00:00:00

  • Emerging strategies for targeting PI3K in gynecologic cancer.

    abstract::Ovarian, endometrial and cervical cancers are the most prevalent gynecologic cancers in the United States and account for significant mortality. Translational research into these cancers has highlighted the distinctive molecular and genomic profiles of these cancers finding that, even within a disease site, the landsc...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Bregar AJ,Growdon WB

    更新日期:2016-02-01 00:00:00

  • The "real-life" variability of CA-125 in ovarian cancer patients.

    abstract:BACKGROUND:The serum CA-125 antigen value has proven to be useful in predicting changes that affect prognosis and management of ovarian cancer; however, interpreting variations in the tumor marker is still not well-defined. Our goal was to further understand the analytical variability of CA-125 in a conventional hospit...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tso E,Elson P,Vanlente F,Markman M

    更新日期:2006-10-01 00:00:00

  • The role of neoadjuvant chemotherapy in the management of patients with advanced stage ovarian cancer: survey results from members of the Society of Gynecologic Oncologists.

    abstract:OBJECTIVE:Recent randomized controlled data suggest that neoadjuvant chemotherapy (NACT) with interval debulking (ID) may produce similar overall survival and progression free survival compared to standard primary cytoreduction followed by chemotherapy. The object of our study was to assess current patterns of care amo...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Dewdney SB,Rimel BJ,Reinhart AJ,Kizer NT,Brooks RA,Massad LS,Zighelboim I

    更新日期:2010-10-01 00:00:00

  • Routine lymph node dissection in the treatment of early stage cancer: are we doing the right thing?

    abstract::The role of elective lymphadenectomy in the treatment of patients with early-stage malignancies, although still commonly performed, remains a matter of controversy. This issue is important in the management of cancers and raises questions about the biologic interpretation of their natural history and about motives for...

    journal_title:Gynecologic oncology

    pub_type: 社论


    authors: Santin AD,Parham GP

    更新日期:1998-01-01 00:00:00

  • The 72-kDa metalloproteinase immunostaining in cervical carcinoma: relationship with lymph nodal involvement.

    abstract:OBJECTIVE:In the present study we detected 72-kDa metalloproteinase expression in our series of early stage cervical carcinomas and analyzed the relationship between 72-kDa metalloproteinase staining and risk of nodal involvement with the goal of identifying a parameter useful in predicting the metastatic potential of ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Garzetti GG,Ciavattini A,Lucarini G,Goteri G,Romanini C,Biagini G

    更新日期:1996-02-01 00:00:00

  • Syndrome of inappropriate antidiuresis in ovarian serous carcinoma with neuroendocrine differentiation.

    abstract::A 58-year-old postmenopausal woman with primary ovarian serous carcinoma presented with the syndrome of inappropriate antidiuresis (SIAD). Preoperative workup showed serum sodium level of 110 mEq/liter and antidiuretic hormone level of 3.3 pg/ml. The serum and urine osmolarity were 239 and 371, respectively. Antidiure...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Taskin M,Barker B,Calanog A,Jormark S

    更新日期:1996-09-01 00:00:00

  • Applicability of the concept of "platinum sensitivity" to recurrent endometrial cancer: the SGSG-012/GOTIC-004/Intergroup study.

    abstract:OBJECTIVE:The concept of "platinum sensitivity" has been widely applied in the management of recurrent ovarian cancer. This study aimed to evaluate the applicability of this concept to recurrent endometrial cancer. PATIENTS AND METHODS:In this multicenter retrospective cohort study, the clinical data of patients with ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Nagao S,Nishio S,Michimae H,Tanabe H,Okada S,Otsuki T,Tanioka M,Fujiwara K,Suzuki M,Kigawa J

    更新日期:2013-12-01 00:00:00

  • Screening as a prognostic factor in cervical cancer: analysis of survival and prognostic factors based on Icelandic population data, 1964-1988.

    abstract::Survival rates were computed for 376 women diagnosed with carcinoma of the uterine cervix between 1964 and 1988. The 5-year survival rate for the entire group was 63%. The effect of age at diagnosis, clinical stage, histopathology, year of diagnosis, and screening program attendance was studied by univariate analysis ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Sigurdsson K,Hrafnkelsson J,Geirsson G,Gudmundsson J,Salvarsdóttir A

    更新日期:1991-10-01 00:00:00

  • Advanced cytoreductive surgery: Asia Pacific perspective.

    abstract::The thoroughness of cytoreductive surgery is the largest contributor to survival for patients with advanced ovarian and primary peritoneal carcinoma. For many years the surgery undertaken by Gynaecologic Oncologists has been tailored to match their surgical training. Future surgical training of Gynaecologic Oncologist...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Crandon AJ,Obermair A

    更新日期:2009-08-01 00:00:00

  • Dactinomycin in the treatment of recurrent or persistent endometrial carcinoma: A Phase II study of the Gynecologic Oncology Group.

    abstract:OBJECTIVES:The search for effective systemic chemotherapy for endometrial cancer is ongoing. Complete responses to current drugs or regimens are infrequent, and overall survival for patients with disease not amenable to surgery or radiation therapy is poor. Dactinomycin has proven activity against a wide variety of sol...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章


    authors: Moore DH,Blessing JA,Dunton C,Buller RE,Reid GC

    更新日期:1999-12-01 00:00:00

  • SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

    abstract:OBJECTIVE:Serous borderline ovarian tumors (SBOT) are slow growing, noninvasive ovarian epithelial neoplasms, which tend to recur as low-grade invasive carcinomas (LGC) with a much worse prognosis. We investigated the molecular basis of this progression. METHODS:We established cultures of three SBOTs and one LGC from ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Woo MM,Salamanca CM,Symowicz J,Stack MS,Miller DM,Leung PC,Gilks CB,Auersperg N

    更新日期:2008-10-01 00:00:00

  • Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions.

    abstract:BACKGROUND:Glucocorticoid receptor (GR) has emerged as an important steroid nuclear receptor in hormone dependent cancers, however few data are available regarding a potential role of GR in endometrial cancer. The aim of this study was to investigate expression of GR in primary and metastatic endometrial cancer lesions...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tangen IL,Veneris JT,Halle MK,Werner HM,Trovik J,Akslen LA,Salvesen HB,Conzen SD,Fleming GF,Krakstad C

    更新日期:2017-12-01 00:00:00

  • Patient reported outcome measures among patients with vulvar cancer at various stages of treatment, recurrence, and survivorship.

    abstract:OBJECTIVE:Our goal was to pragmatically describe patient reported outcomes (PROs) in a typical clinic population of vulvar cancer patients, as prior studies of vulvar cancer PROs have examined clinical trial participants. METHODS:A prospective PRO program was implemented in the Gynecologic Oncology clinic of a tertiar...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Alimena S,Sullivan MW,Philp L,Dorney K,Hubbell H,Del Carmen MG,Goodman A,Bregar A,Growdon WB,Eisenhauer EL,Sisodia RC

    更新日期:2021-01-01 00:00:00

  • Role of high-risk human papillomavirus (HPV) mRNA testing in the prediction of residual disease after conisation for high-grade cervical intraepithelial neoplasia.

    abstract:OBJECTIVE:To evaluate testing for high-risk human papillomavirus (HR HPV) E6/E7 mRNA transcripts 6 months after conisation for cervical intraepithelial neoplasia grade 2 or worse (CIN2+) to determine the risk of residual CIN2+. METHODS:We prospectively followed 344 women treated for CIN2+ by conisation. HR HPV mRNA te...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Tropé A,Jonassen CM,Sjøborg KD,Nygård M,Dahl FA,Alfsen GC,Lie AK

    更新日期:2011-11-01 00:00:00

  • The Wertheim hysterectomy: Development, modifications, and impact in the present day.

    abstract::Ernst Wertheim was a pioneer in the history of the surgical treatment of cervical cancer. His English-language manuscript "The extended abdominal operation for carcinoma uteri (based on 500 operative cases)," which was published in 1912, detailed his standardization of the radical hysterectomy and formed the basis of ...

    journal_title:Gynecologic oncology

    pub_type: 历史文章,杂志文章


    authors: Swailes AL,Gockley A,Phaëton R,Kesterson JP

    更新日期:2017-04-01 00:00:00

  • Validation of a new HPV self-sampling device for cervical cancer screening: The Cervical and Self-Sample In Screening (CASSIS) study.

    abstract:OBJECTIVE:We compared the self-sampling performance of the newly designed HerSwab™ device with a physician-collected cervical sample and another self-sample using the cobas® PCR Female swab for the detection of cervical intraepithelial neoplasia (CIN) and cancer. METHODS:Women referred for colposcopy at McGill Univers...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,随机对照试验


    authors: El-Zein M,Bouten S,Louvanto K,Gilbert L,Gotlieb W,Hemmings R,Behr MA,Franco EL,CASSIS Study Group.

    更新日期:2018-06-01 00:00:00

  • Isolated recurrence at the residual uterine cervix after abdominal radical trachelectomy for early cervical cancer.

    abstract:BACKGROUND:We report an isolated recurrence at the residual cervix shortly after abdominal radical trachelectomy for cervical cancer. CASE:A 34-year-old woman underwent radical abdominal trachelectomy and pelvic lymphadenectomy for FIGO stage IB1 squamous cell cervical cancer. The tumor measured 10 mm in maximum diame...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Bader AA,Tamussino KF,Moinfar F,Bjelic-Radisic V,Winter R

    更新日期:2005-12-01 00:00:00

  • Vulvar epithelioid sarcoma in pregnancy.

    abstract:BACKGROUND:Epithelioid sarcoma is a soft tissue tumor rarely found centrally and even less commonly on the vulva. Vulvar sarcoma in pregnancy is also exceedingly rare with only five cases reported to date, none of which have been an epithelioid sarcoma. CASE:We report a case of a 29-year-old woman presenting with a vu...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Moore RG,Steinhoff MM,Granai CO,DeMars LR

    更新日期:2002-04-01 00:00:00

  • Survival implications of staging lymphadenectomy for non-endometrioid endometrial cancers.

    abstract:PURPOSE:To determine, in patients with non-endometrioid endometrial carcinoma, 1) survival benefit associated with pelvic lymphadenectomy (LND), 2) survival benefit for para-aortic lymphadenectomy performed in addition to pelvic lymphadenectomy, and 3) association between number of lymph nodes removed and survival. ME...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Venigalla S,Chowdhry AK,Shalowitz DI

    更新日期:2018-06-01 00:00:00

  • Anti-Yo positive paraneoplastic cerebellar degeneration associated with ovarian carcinoma: case report and review of the literature.

    abstract::Paraneoplastic cerebellar degeneration (PCD) is a rare nonmetastatic neurological complication in cancer patients. Anti-Yo is one of the anti-onconeural antibodies found in PCD patients. It is believed that anti-Yo occurs almost always in women and is most likely associated with gynecologic or breast cancers, although...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Cao Y,Abbas J,Wu X,Dooley J,van Amburg AL

    更新日期:1999-10-01 00:00:00

  • A novel technique for gynecologic oncology surgery in the presence of abdominal wall mesh prosthesis.

    abstract::Incisional herniae are relatively frequent complications of abdominal incisions. Hernia repair techniques have taken advantage of the strength provided by prosthetic mesh grafts. Subsequent surgery in these patients must incorporate a strategy for managing the mesh material. The goals are adequate exposure for surgery...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Buekers TE,Sorosky JI,Buller RE

    更新日期:1998-07-01 00:00:00

  • p16/Ki-67 dual staining in cervico-vaginal cytology: correlation with histology, Human Papillomavirus detection and genotyping in women undergoing colposcopy.

    abstract:OBJECTIVES:To evaluate the CINtec PLUS assay (mtm laboratories), a new immunocytochemical method for the simultaneous detection of p16(INK4a) and Ki-67, in liquid-based cervico-vaginal cytology, investigating the association of the dual staining with HPV infection and genotyping as well as cytological and histological ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Donà MG,Vocaturo A,Giuliani M,Ronchetti L,Rollo F,Pescarmona E,Carosi M,Vocaturo G,Benevolo M

    更新日期:2012-08-01 00:00:00

  • Detection of endometrial cancer via molecular analysis of DNA collected with vaginal tampons.

    abstract:OBJECTIVE:We demonstrate the feasibility of detecting EC by combining minimally-invasive specimen collection techniques with sensitive molecular testing. METHODS:Prior to hysterectomy for EC or benign indications, women collected vaginal pool samples with intravaginal tampons and underwent endometrial brushing. Specim...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Bakkum-Gamez JN,Wentzensen N,Maurer MJ,Hawthorne KM,Voss JS,Kroneman TN,Famuyide AO,Clayton AC,Halling KC,Kerr SE,Cliby WA,Dowdy SC,Kipp BR,Mariani A,Oberg AL,Podratz KC,Shridhar V,Sherman ME

    更新日期:2015-04-01 00:00:00

  • Lymph node dissection in endometrial cancer and clinical outcome: A population-based study in 5546 patients.

    abstract:BACKGROUND:According to current treatment guidelines, comprehensive surgical staging procedures in endometrial cancer confined to the uterus depend on uterine risk factors: a systematic lymph node dissection (LND) is recommended in high risk patients and should be omitted in low risk patients. Its role in intermediate ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Pölcher M,Rottmann M,Brugger S,Mahner S,Dannecker C,Kiechle M,Brambs C,Grab D,Anthuber C,von Koch F,Schnelzer A,Engel J

    更新日期:2019-07-01 00:00:00

  • Predictors of optimal cytoreduction in patients with newly diagnosed advanced-stage epithelial ovarian cancer: Time to incorporate laparoscopic assessment into the standard of care.

    abstract::The standard management of advanced-stage ovarian cancer has been a subject of debate, and much controversy remains as to whether patients should have primary cytoreductive surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval cytoreductive surgery. In addition, there is increasing evidence...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Gómez-Hidalgo NR,Martinez-Cannon BA,Nick AM,Lu KH,Sood AK,Coleman RL,Ramirez PT

    更新日期:2015-06-01 00:00:00

  • Outcomes of primary surgical cytoreduction in patients with BRCA-associated high-grade serous ovarian carcinoma.

    abstract:OBJECTIVE:BRCA-associated and sporadic ovarian cancers have different pathologic and clinical features. Our goal was to determine if BRCA mutation status is an independent predictor of residual tumor volume following primary surgical cytoreduction. METHODS:We conducted a retrospective analysis of patients with FIGO st...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Hyman DM,Long KC,Tanner EJ,Grisham RN,Arnold AG,Bhatia J,Phillips MF,Spriggs DR,Soslow RA,Kauff ND,Levine DA

    更新日期:2012-08-01 00:00:00

  • A phase II study of cetuximab/paclitaxel/carboplatin for the initial treatment of advanced-stage ovarian, primary peritoneal, or fallopian tube cancer.

    abstract:OBJECTIVE:Determine the safety and efficacy of cetuximab plus paclitaxel and carboplatin as initial treatment of stage III/IV ovarian cancer. METHODS:An initial intravenous [IV] dose of cetuximab (400 mg/m(2)) was administered over 120 min followed by weekly IV infusions of cetuximab (250 mg/m(2)) administered over 60...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Konner J,Schilder RJ,DeRosa FA,Gerst SR,Tew WP,Sabbatini PJ,Hensley ML,Spriggs DR,Aghajanian CA

    更新日期:2008-08-01 00:00:00

  • Cytoreduction of diaphragmatic metastasis from ovarian cancer with involvement of the liver using a ventral liver mobilization technique.

    abstract:OBJECTIVE:Upper abdominal spreading of advanced-stage ovarian cancer often involves the diaphragm. In addition, bulky diaphragmatic tumors occasionally infiltrate the liver. Here, we describe our early experiences with a ventral liver mobilization technique to remove diaphragmatic tumors with liver involvement. METHOD...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kato K,Katsuda T,Takeshima N

    更新日期:2016-03-01 00:00:00

  • Advanced endometrial cancer detected at 7 months after childbirth.

    abstract::It is very rare to find endometrial cancers arising within a short period following childbirth, presumably because pregnancy has a protective effect against endometrial cancer mediated by elevated secretion of progesterone. We present the case of a 30-year-old Japanese woman with stage IIIC endometrial cancer that was...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Kodama J,Yoshinouchi M,Miyagi Y,Kobashi Y,Kamimura S,Okuda H,Kudo T

    更新日期:1997-03-01 00:00:00