Endometrial response to endogenous hormones after pelvic irradiation for genital malignancies.

abstract：OBJECTIVE:To evaluate the effect of margin status and radiation dose in patients treated with radiation therapy (RT) for vulvar cancer. Clinical outcomes included vulvar recurrence (VR), relapse-free survival (RFS) and overall survival (OS). METHODS:We retrospectively reviewed the records of 300 patients with Stage I-...

journal_title：Gynecologic oncology

authors： Viswanathan AN,Pinto AP,Schultz D,Berkowitz R,Crum CP

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To quantify the effect of race/ethnicity on risk of complete and partial molar pregnancy. METHODS:We conducted a cross-sectional study including women who were followed for complete or partial mole and those who had a live singleton birth in a teaching hospital in the northeastern United States between 2000 ...

journal_title：Gynecologic oncology

authors： Melamed A,Gockley AA,Joseph NT,Sun SY,Clapp MA,Goldstein DP,Berkowitz RS,Horowitz NS

更新日期：2016-10-01 00:00:00

abstract：:A 58-year-old postmenopausal woman with primary ovarian serous carcinoma presented with the syndrome of inappropriate antidiuresis (SIAD). Preoperative workup showed serum sodium level of 110 mEq/liter and antidiuretic hormone level of 3.3 pg/ml. The serum and urine osmolarity were 239 and 371, respectively. Antidiure...

journal_title：Gynecologic oncology

authors： Taskin M,Barker B,Calanog A,Jormark S

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Improved treatment for advanced cervical cancer is needed; currently, treatment options include combined chemotherapy and bevacizumab or pembrolizumab monotherapy for PD-L1 positive disease. PIK3CA and KRAS mutations have been reported in cervical cancers; this study therefore tested dual inhibition of PI3K ...

journal_title：Gynecologic oncology

authors： Liu JF,Gray KP,Wright AA,Campos S,Konstantinopoulos PA,Peralta A,MacNeill K,Morrissey S,Whalen C,Dillon D,Matulonis UA

更新日期：2019-07-01 00:00:00

abstract：:In a prospective, randomized, double-blind trial the combination betamethasone-dixyrazine was compared with high-dose metoclopramide as antiemetic treatment during combination chemotherapy (melphalan-doxorubicin and cisplatin) of ovarian carcinoma. Of 40 evaluable patients, 15 (38%) had previous experience with chemot...

journal_title：Gynecologic oncology

authors： Sorbe B,Hallén C

更新日期：1989-08-01 00:00:00

abstract：:From 1977 to 1984 the Gynecologic Oncology Group (GOG) conducted a prospective clinical and surgical staging protocol of squamous cell carcinoma of the vulva (n = 637). The patients with superficial (5 mm or less invasion) lesions were the subject of a previous report (n = 272). The subject of this report is on factor...

journal_title：Gynecologic oncology

authors： Homesley HD,Bundy BN,Sedlis A,Yordan E,Berek JS,Jahshan A,Mortel R

更新日期：1993-06-01 00:00:00

abstract：:The existing means of detecting recurrent ovarian carcinoma are notoriously poor. Positron emission tomography (PET) is a form of computer-assisted imaging which produces images reflective of the biochemistry of the tissues rather than their physical characteristics. PET imaging with the positron emitting glucose anal...

journal_title：Gynecologic oncology

authors： Karlan BY,Hawkins R,Hoh C,Lee M,Tse N,Cane P,Glaspy J

更新日期：1993-11-01 00:00:00

abstract：:Recombinant human tumor necrosis factor (rHuTNF) is a macrophage-secretory protein with antitumor activity. In vivo and in vitro cytotoxicity studies have been carried out to test the effectiveness of rHuTNF alone or in combination with chemotherapeutic agents. We have evaluated the direct cytotoxic effect of rHuTNF o...

journal_title：Gynecologic oncology

authors： Vigani A,Chiara S,Miglietta L,Repetto L,Conte PF,Cimoli G,Morelli L,Billi G,Parodi S,Russo P

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Central nervous system (CNS) metastases from an ovarian malignancy are uncommon. The long-term prognosis for these patients is poor, with studies reporting a mean survival of less than 12 months. CASES:We present three ovarian cancer patients who developed metastatic disease to the brain. All patients were ...

journal_title：Gynecologic oncology

authors： Brown JV 3rd,Goldstein BH,Duma CM,Rettenmaier MA,Micha JP

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were twofold: to prospectively assess whether expressed intention to undergo prophylactic oophorectomy translated into uptake and to evaluate the psychological impact of the procedure in a sample of unaffected women with a strong family history of breast/ovarian cancer. METHODS:...

journal_title：Gynecologic oncology

authors： Tiller K,Meiser B,Butow P,Clifton M,Thewes B,Friedlander M,Tucker K

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this case-controlled study was to determine the prevalence of anemia and incidence of perioperative blood transfusions in patients undergoing treatment for advanced ovarian cancer with neoadjuvant chemotherapy (NACT) or primary debulking surgery (PDS). METHODS:We performed a single institution...

journal_title：Gynecologic oncology

authors： O'Shea A,McCool K,Harrison R,Sampene E,Connor J,Barroilhet L

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Cutaneous lymphangitis carcinomatosis from cervical carcinoma is a very rare form of tumor metastatization; only anecdotal cases are reported in the literature. Most of the patients with skin relapse experienced metastasis as a single or multiple nodules. CASE:A case of cutaneous lymphangitis carcinomatosis...

journal_title：Gynecologic oncology

authors： Palaia I,Angioli R,Cutillo G,Manci N,Panici PB

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:Limited knowledge exists about the value of tumor size in surgically treated cervical cancer (CX) using a tumor size of 2 cm as cut-off value. METHODS:A total of 366 cases of CX FIGO stage IB who received upfront surgery were evaluated regarding tumor size, the prediction of pelvic lymph node involvement, a...

journal_title：Gynecologic oncology

authors： Horn LC,Bilek K,Fischer U,Einenkel J,Hentschel B

更新日期：2014-07-01 00:00:00

abstract：:Young women diagnosed with breast cancer typically face systemic treatments that may delay childbearing or permanently impair their fertility. These concerns add to the stress experienced by young cancer survivors. Timely counseling and providing fertility preservation through cryopreservation of eggs or embryos have ...

journal_title：Gynecologic oncology

authors： Westphal LM,Wapnir IL

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:The rationale for lymphadenectomy in primary peritoneal cancer (PPC) is unclear. We sought to define the pattern of lymphatic metastasis in PPC and propose evidence-based rationale for lymphadenectomy in relevant cases. METHODS:Patients with PPC undergoing primary surgery at Mayo Clinic were identified. D...

journal_title：Gynecologic oncology

authors： Aletti GD,Powless C,Bakkum-Gamez J,Wilson TO,Podratz KC,Cliby WA

更新日期：2009-07-01 00:00:00

abstract：:Nucleolar Organizer Regions (NORs) code for ribosomal RNA and are thought to be an accurate representation of the percentage of cells in S-phase. NORs are associated with nonhistone nucleoproteins, which can be stained with silver (AgNORs). An increased number of AgNORs has been observed in many malignancies. AgNORs w...

journal_title：Gynecologic oncology

authors： Chalas E,Chumas J,Barbieri R,Mann WJ

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this article is to review the data, rationale, and recommendations of vaginal brachytherapy (VBT) in the post-operative treatment of endometrial cancer patients. METHODS:The authors performed a thorough review of the medical literature regarding the use of adjuvant VBT in the treatment of endo...

journal_title：Gynecologic oncology

authors： Harkenrider MM,Block AM,Siddiqui ZA,Small W Jr

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVES:Uterine adenosarcomas (AS) are rare tumors composed of malignant stromal and benign epithelial components. We sought to evaluate the role of primary surgery, adjuvant treatments, and salvage therapies for patients with uterine adenosarcomas. METHODS:We identified all patients diagnosed with AS from 1990 to ...

journal_title：Gynecologic oncology

authors： Tanner EJ,Toussaint T,Leitao MM Jr,Hensley ML,Soslow RA,Gardner GJ,Jewell EL

更新日期：2013-04-01 00:00:00

abstract：:Sixty-eight patients with FIGO stage I, grade 2 or 3 adenocarcinoma of the endometrium were treated according to a protocol involving 10 Gy external pelvic irradiation, prompt hysterectomy with surgical staging, and postoperative therapy individualized according to surgical-pathologic findings. Five-year survival for ...

journal_title：Gynecologic oncology

authors： Shimm DS,Wang CC,Fuller AF Jr,Nelson JH Jr,Nikrui N,Young RH,Scully RE

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:Conservative surgery followed by platinum-based chemotherapy is considered the standard approach for pure ovarian dysgerminoma (POD), except for correctly staged IA patients. The aim of study was to evaluate the outcome of IA POD patients with incomplete surgical staging in order to define the proper manageme...

journal_title：Gynecologic oncology

authors： Mangili G,Sigismondi C,Lorusso D,Cormio G,Scollo P,Viganò R,Gamucci T,Candiani M,Pignata S

更新日期：2011-05-01 00:00:00

abstract：INTRODUCTION:Randomized trials have demonstrated significant improvements in progression-free survival (PFS) with consolidation paclitaxel (P) and bevacizumab (B) following cytoreduction and adjuvant carboplatin/paclitaxel (CP) for advanced epithelial ovarian cancer (EOC). We sought to evaluate the cost-effectiveness (...

journal_title：Gynecologic oncology

authors： Lesnock JL,Farris C,Krivak TC,Smith KJ,Markman M

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The goal of this work was to determine the cellular content of inhibin and p53 in granulosa cell tumors (GCTs). METHODS:Clinical records of 47 patients (mean age, 54 years; range, 20-85 years) presenting with GCT surgically managed at our institution were abstracted. International Federation of Gynecology st...

journal_title：Gynecologic oncology

authors： Gebhart JB,Roche PC,Keeney GL,Lesnick TG,Podratz KC

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:Increased activity of Sp family of transcription factors is a frequent and critical event in cancer development and progression. Genes governing tumor growth, invasion and angiogenesis are regulated by Sp factors, like Sp1, Sp3 or Sp4, and are frequently over-expressed in tumors. Targeting Sp factors has been...

journal_title：Gynecologic oncology

authors： Previdi S,Malek A,Albertini V,Riva C,Capella C,Broggini M,Carbone GM,Rohr J,Catapano CV

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The prognosis of cancer patients with distant metastases is extremely poor. CASE:A 51-year-old Japanese woman with Stage IIIc serous cystoadenocarcinoma of the ovary achieved complete remission. At 30 and 39 months after the initiation of therapy, solitary brain and then spleen metastases without intraperit...

journal_title：Gynecologic oncology

authors： Mikami M,Suzuki A,Takehara K,Komiyama S,Ishikawa M,Hirose T

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. CASE:We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell c...

journal_title：Gynecologic oncology

authors： Ohishi Y,Kaku T,Kaneki E,Wake N,Tsuneyoshi M

更新日期：2007-05-01 00:00:00

abstract：:The therapeutic value of 131I-OC125, a radiolabeled monoclonal antibody directed against a human ovarian tumor associated antigen CA125, was examined in an ascites forming intraperitoneal human ovarian carcinoma nude mouse model. Nude mice were injected intraperitoneally with NIH:OVCAR3 cells. Twenty-one days after tu...

journal_title：Gynecologic oncology

authors： Manetta A,Satyaswaroop PG,Hamilton T,Ozols R,Mortel R

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Herpes gestationis (HG) is a rare, recurrent, pruritic, vesicobullous dermatosis occurring predominantly in pregnancy and seldom in early puerperium. Reports of the association of HG with choriocarcinoma are extremely rare and this case highlights such a possible link. CASE:This case focuses on the late pos...

journal_title：Gynecologic oncology

authors： Djahansouzi S,Nestle-Kraemling C,Dall P,Bender HG,Hanstein B

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Younger patients with invasive epithelial ovarian cancer (EOC) frequently want to preserve their fertility, but the role of fertility-sparing surgery in EOC has not been well defined. We therefore assessed tumor recurrence, patient survival and pregnancy outcomes in patients with invasive EOC who underwent fe...

journal_title：Gynecologic oncology

authors： Park JY,Kim DY,Suh DS,Kim JH,Kim YM,Kim YT,Nam JH

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:Diagnosis and treatment for a life threatening illness such as cancer are known to be psychologically impactful. However, little is known about the influence that non-cancer life stressors have on the quality of life (QOL) of ovarian cancer patients. The goal of the present study was to examine associations ...

journal_title：Gynecologic oncology

authors： Lutgendorf SK,Slavich GM,Degeest K,Goodheart M,Bender D,Thaker PH,Penedo F,Zimmerman B,Lucci J 3rd,Mendez L,Collins K,Sood AK

更新日期：2013-12-01 00:00:00

abstract：:Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their perimenopausal years. Presenting symptoms may be vague and mimic other benign uterine conditions. P...

journal_title：Gynecologic oncology

authors： Roberts ME,Aynardi JT,Chu CS

更新日期：2018-12-01 00:00:00