Abstract：
BACKGROUND:The surveillance of non-muscle-invasive bladder cancer (NMIBC) is usually performed by cystoscopy and cytology. Until today, no effective urinary biomarker has been used to reduce the morbidity and cost associated with these procedures. OBJECTIVE:To describe the performance of urinary biomarkers in the surveillance of NMIBC. EVIDENCE ACQUISITION:on August 1, 2018, a bibliographic search was carried out in Pubmed, Embase and Cochrane Library, limited to the last 10 years, with the terms: bladder cancer, recurrence, detection and urine marker.973 registers were obtained, and 27 publications were selected following the PRISMA recommendations. EVIDENCE SYNTHESIS:The negative predictive values (NPV) of several assays could reduce the number of cystoscopies in NMIBC surveillance. Six transcription-factor trials had an NPV rate greater than 90%, and one of them can be performed at the control point. Six transcription-factors evaluations describe anticipated diagnosis between 68% and 83% of their "false positives". Two transcription factors and one protein assays proved reduction between 23% and 35% of surveillance cystoscopies. Nowadays, cell-based assays are restricted to reflex test after doubtful cytologies. CONCLUSION:There are few studies analysing the improvement of the NMIBC surveillance protocols. Several transcription factor assays are more precise and allow anticipatory diagnosis. Currently, there are no comparative studies between alternative surveillance protocols and classic ones.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Agreda Castañeda F,Raventós Busquets CX,Morote Robles Jdoi
10.1016/j.acuro.2019.03.001subject
Has Abstractpub_date
2019-10-01 00:00:00pages
404-413issue
8eissn
0210-4806issn
1699-7980pii
S0210-4806(19)30041-5journal_volume
43pub_type
杂志文章,评审abstract：INTRODUCTION:The short-term results of endoscopic treatment of vesicoureteral reflux (VUR) are excellent. Over time, however, a number of patients have been identified for whom VUR reappeared after being resolved with this technique. The aim of this study was to analyse the factors related to this event. MATERIAL AND ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2017.11.006
更新日期：2018-06-01 00:00:00
abstract：:Instrumentation of lower urinary tract is a predisposing factor for the development of urinary infection. Incidence of infective complications following urethrocystoscopy has been evaluated in a multicenter, prospective, comparative and randomized study in 2,284 patients, who had a previous negative urine culture. Pat...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1993-03-01 00:00:00
abstract：:Report on the results of a survey conducted among Urology residents in the Valencian Community. Evaluation of the training level of the MIR system, both overall and by areas. Presentation of the views obtained with regard to possible modifications to raise their training level and improve their professional future. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:We studied two groups of patients in order to evaluate the frequency of association between renal dysplasia and vesicoureteral reflux. The first was composed of 19 patients with dysplastic kidneys, 15 of whom were studied by means of micturition cystourethrography. The second group was made up of 86 patients with 124 ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVE:To study the influence, in terms of prognosis, of the finding of seminal vesicle involvement in patients with prostate adenocarcinoma treated with radical prostatectomy. MATERIAL AND METHOD:We reviewed a series of patients with seminal vesicle involvement with clinically localized prostate adenocarcinoma who...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.05.009
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:To validate the technique of selective sentinel node biopsy for diagnosing and staging intermediate to high-risk prostate cancer by comparing the technique with conventional extended lymphadenectomy (eLFD) in a prospective, longitudinal comparative study. METHODS:We applied the technique to 45 patients. Afte...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2016.06.002
更新日期：2017-01-01 00:00:00
abstract：:We report a case of a carcinoid tumor originated in testicle associated with mature teratoma in a 31 years old male. Primary gonadal location of this tumor is unusual, moreover when associated with teratoma. Early diagnosis and treatment determine the prognostic of the patients affected of this neoplasm since the only...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(08)73863-4
更新日期：2008-04-01 00:00:00
abstract：:As a result of finding some ectopic adrenal debris in the spermatic cord, the present report studies the embryogenesis and clinical implications that can derive from the existence of the referred adrenal debris. The relevant literature is reviewed and six new cases contributed, one of them bilateral. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：INTRODUCTION:Pyeloureteral duplication is often associated to ureterocele and ectopic ureter. Therapeutic approach of ureterocele is actually a debated subject because of the differences treatments. There is controversy about the classic heminefrectomy with ureterocele aspiration and the minimal invasive endoscopic app...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(01)72709-x
更新日期：2001-11-01 00:00:00
abstract：:The fate of some infiltrant tumours of the bladder locally advanced (pT2-3NxM0) which were radically resected, with or without association to other treatments, has been similar to those in which initial radical treated was used. To carry out simultaneously a radical RTU as a local action plus systemic chemotherapy (M-...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1992-03-01 00:00:00
abstract：:Melanosis of the bladder is a rare entity characterized by anomalous deposits of melanin-containing pigment on the vesical urothelium without melanocytic atypia or associated malignant melanoma. To our knowledge and following such strict criteria, there are only five cases previously reported. The biological potential...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(04)73144-7
更新日期：2004-09-01 00:00:00
abstract：GOALS:To estimate the prevalence, age distribution, impact on quality of life and type of urinary incontinence (UI) in women over 30 years in Mallorca (Spain). MATERIAL AND METHODS:Cross-sectional descriptive study on a randomized sample of 673 women in the health district affiliated to Son Llàtzer Hospital and the 14...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2012.11.004
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Northern African (NAf) men show a high incidence of advanced prostate cancer (PCa) at diagnosis. Several studies suggested the existence of ethnic differences in the PCa aggressiveness and this has led to some concerns related to the inclusion of some ethnic groups into active surveillance protocols. OBJECT...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2016.01.011
更新日期：2016-11-01 00:00:00
abstract：:Presentation of 11 cases of retroperitoneal sarcoma. Mean time from the beginning of symptoms to diagnosis is 6 months. The primary complementary study is CT. Surgery was performed in all cases, using complete resection in 6 cases, and partial resection in 5. Ten patients relapsed. 9 of which were treated with surgica...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVES:To analyze the surgical and oncologic outcome of prospective experience with laparoscopic partial nephrectomy. We describe the surgical technique and mid term oncological results achieved. MATERIAL AND METHODS:60 patients were operated with this technique between June 2005 and June 2009. The mean age of pat...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2011.03.015
更新日期：2011-09-01 00:00:00
abstract：:One of the various therapeutic options currently used in erectile dysfunction (ED), vacuum is a procedure that should not be ruled out as it can benefit certain types of patient. To understand each patient's response and usage readiness, a vacuum test is routinely performed by the andrology service as part of the diag...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章
doi：10.1016/s0210-4806(00)72437-5
更新日期：2000-03-01 00:00:00
abstract：:The epidermic growth factor (EGF) is a polypeptide which stimulates tissue proliferation. The mechanism of action takes place through an specific membrane receptor, known as the EGFR. Recent scientific contributions have allowed to know its implication in various tumoral processes (breast, ovary, bladder, etc), so tha...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The germinal bilateral tumor represents from 1 to 4% of the testicle tumors, and it usually turns to be one of the most difficult ones when talking about diagnosis and treatment. We are attaching a 30 years old patient case, with a diagnosis consisting in a seminoma with yolk sac tumor area from the left testicle, tha...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：2003-02-01 00:00:00
abstract：:Alkaline encrusted cystitis is characterized by the formation of calcareous plaques in the bladder mucosa and submucosa in the presence of several factors: infection by urolithic organisms, earlier pathology of the vesical wall and precipitation of calcium phosphate salts. Treatment includes: urine acidification, corr...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:Laparoscopic surgery is a surgical technique the urologist should add to his surgical armamentarium. Its performance tries to mimic the surgical phases of open surgery, and also its indications. Laparoscopic partial nephrectomy is a sophisticated technique that requires wide experience in the performance of endoscopic...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(06)73486-6
更新日期：2006-05-01 00:00:00
abstract：:We show a big renal cell carcinoma case in an aged woman with many pathology associated. In view of the family refuse to make the radical surgery and the high surgical risk we decided to apply transarterial embolization treatment with polivinil alcohol particles (PVA). 28 months later the patient becames with no sympt...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73246-0
更新日期：2005-03-01 00:00:00
abstract：:We present 3 new cases of urethral parameatal cysts in paediatric age. Literature is reviewed and histological data and ambulatory management are discussed. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(07)73597-0
更新日期：2007-01-01 00:00:00
abstract：:Severe vesicouretheral reflux sometimes causes terminal renal failure which then requires renal transplantation. In these patients it may be necessary to perform bilateral nephrectomy when associated to serious hypertension or urinary infections with a significant clinical impact. This paper presents the clinical pict...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:Presentation of a review of 10 paediatric patients with tumour of the testis vitelline sack, to report our experience in the management of this pathology. Mean age was 20 months (14-32), and the interval of the study was from 1970 to 1994. After orchiectomy, 7 children were included in stage I, 1 in stage II, and 2 in...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVES:The testicular tumors are frequent in the young adult, coinciding with the incorporation to the Military Service. The objective of our work is to evaluate the tumoral characteristic, its evolution with the time and the result of the treatments used in our center for this type of tumors. MATERIAL AND METHODS...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73275-7
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:We report a new case of symptomatic myelolipoma of the adrenal gland. We analyse clinical, diagnostic, histopathologic and therapeutic aspects. METHOD AND RESULTS:Surgical excision was performed by lumbotomy. The patient was asymptomatic after surgery. DISCUSSION:Adrenal myelolipoma is norfunctioning benign...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：CONTEXT:The purpose of this article is to review the history of robotic surgery, its impact on teaching as well as a description of historical and current robots used in the medical arena. SUMMARY OF EVIDENCE:Although the history of robots dates back to 2000 years or more, the last two decades have seen an outstanding...
journal_title：Actas urologicas espanolas
pub_type： 历史文章,杂志文章
doi：10.1016/j.acuro.2011.04.005
更新日期：2011-10-01 00:00:00
abstract：:In Spain, based on the IIEF, 19% of males between 25 and 70 years old present some degree of erectile dysfunction (ED). Therefore, around 2,000,000 Spanish men present this condition and could require medical attention for it. Here, we present an up-date of the most important aspects of erectile dysfunction (pathophys...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(02)72844-1
更新日期：2002-10-01 00:00:00
abstract：:Presentation of one case of malignant fibrohistiocytoma derived from the renal capsule. While conducting a bibliographic review the low incidence of this tumoration of renal origin was noted. The difficulties in differentiating this entity from a secondary renal invasion by a malignant fibrohistiocytoma derived from o...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
abstract：:We present our experience in the diagnosis-through-image with 25 primitive retroperitoneal tumours over a period of 17 years. The histological type most frequently found was that derived from mesodermal tissue (64%). Abdominal pain and mass were the typical symptoms of the presentation. The paper analyzes the radiolog...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1991-03-01 00:00:00
