Abstract：
:The epidermic growth factor (EGF) is a polypeptide which stimulates tissue proliferation. The mechanism of action takes place through an specific membrane receptor, known as the EGFR. Recent scientific contributions have allowed to know its implication in various tumoral processes (breast, ovary, bladder, etc), so that its expression may be used as a major prognostic factor. The objective of this work is to quantify and analyze the epidermic growth factor receptor (EGFR) in surface and invasive vesical carcinoma. To this end, 43 tissular samples divided in two groups were studied. The groups were: 1) Group 1 or control group, comprising 14 samples of "control" vesico-urothelial tissue, and 2) Group 2, assembling 29 patients with vesical carcinoma (17 surface and 12 infiltrant). All tissue samples underwent a process of homogenization and subsequent determination of membrane EGFR by means of radioimmunoassay (EGFR-Receptor Assay, Vienna Lab, Labordiagnostika GmbH). Our results demonstrate the expression of EGFR in both control and tumoral vesico-urothelial tissue in 100% of cases, with detection of significantly higher concentrations (p) in samples from vesical carcinoma than in those from control specimens (15.24 vs. 5.02 fmol/mg protein) and higher levels in infiltrant rather than in surface vesical carcinomas (18.92 vs. 11.4 fmol/mg protein).
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Moreno Sierra J,Maestro de las Casas M,Ortega Heredia MD,Hermida Gutiérrez J,Resel Estevez Lsubject
Has Abstractpub_date
1994-03-01 00:00:00pages
215-20issue
3eissn
0210-4806issn
1699-7980journal_volume
18pub_type
杂志文章abstract：:Male feminization is an uncommon and complex phenomenon which occurs as a consequence of an imbalance in the effective oestrogen/androgen relationship. One of the many approaches used in the treatment of idiopathic male infertility is hCG/hMG stimulation. This paper reports one case of an infertile male treated with h...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1995-05-01 00:00:00
abstract：:We show a big renal cell carcinoma case in an aged woman with many pathology associated. In view of the family refuse to make the radical surgery and the high surgical risk we decided to apply transarterial embolization treatment with polivinil alcohol particles (PVA). 28 months later the patient becames with no sympt...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73246-0
更新日期：2005-03-01 00:00:00
abstract：:Urethral duplication is a rare congenital anomaly affecting mainly males and being usually diagnosed during paedriatric age. We report a 20 year old male complaining of double urethral meatus with double urinary stream. Physical examination confirmed and additional hypospadic meatus below a normally placed urethral me...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73204-6
更新日期：2005-01-01 00:00:00
abstract：:Wilms tumour is an infantile neoplasia with low incidence in adults. Worldwide literature describes 260 cases but only 50 meet the diagnostic criteria described by Kilton. This paper presents one case diagnosed in our service and includes a review of the literature. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1991-09-01 00:00:00
abstract：:The presence of neoplasms in patients with renal transplant in a higher frequency than in general people is known since a long time. The most frequent tumours were the skin tumours, followed by other tumours common in immunosuppressed patients. The ain of this work has been study the frequency, type, diagnosis, treatm...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：
更新日期：1998-11-01 00:00:00
abstract：:Endometriosis is defined by the presence of functionally active endometria in ectopic position; so when its clinical behaviour adopts the characteristics of tumoration, endometrioma is accepted as an alternative name. Location of this pathology in the urinary apparatus is uncommon in terms of incidence, since the blad...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Orbital metastasis is an unusual localization within tumoral dissemination of prostatic cancer. Similarly, it is rare that orbital metastasis might be responsible for the clinic manifestations that determine the initial diagnosis of neoplasia. We illustrate the case of a patient suffering from prostatic adernocarcinom...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(03)72974-x
更新日期：2003-07-01 00:00:00
abstract：INTRODUCTION:It has been reported that varicocele might promote angiogenesis. However, it is not clearly identified how angiogenesis affect testicular morphology or spermatogenic activity. The objective of the study is to investigate the effect of spironolactone, as an angiogenesis inhibitor, on the ipsilateral testis ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2013.12.013
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVES:To perform the linguistic and psychometric validation of the Spanish version of the BSW (Benefit, Satisfaction and Willingness to continue) questionnaire. MATERIAL AND METHODS:Epidemiologic, observational, multicenter, prospective (October 2008-February 2009) study in patients ≥40 years old with de novo ove...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2013.03.005
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To describe the surgical technique of AMS MiniArc swing system for the treatment of female urinary incontinence, evaluate its results and complications. METHOD:We performed a retrospective study of surgery with AMS Miniarc swing system. From august 2007 to march 2009, 135 patients with urinary incontinence (...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：2010-04-01 00:00:00
abstract：OBJECTIVE:To review the outcome of bulbar urethroplasty using two stage surgical techniques. MATERIAL AND METHODS:Twenty-two of the 35 patients studied corresponded to end-to-end urethroplasty (ATT) and 13 to dorsal onlay graft (DOG) in preputial skin or oral mucosa variants. Clinical outcome was considered a failure ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2012.03.006
更新日期：2013-03-01 00:00:00
abstract：:Prostate cancer (PCa) is the second leading cause of cancer-related mortality and the most frequently diagnosed male malignant disease among men. The manifestation of PCa ranges from indolent to highly aggressive disease and due to this high variation in PCa progression, the diagnosis and subsequent treatment planning...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2019.08.003
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVE:To assess the ability of multiparametric prostate magnetic resonance imaging (mpMRI) to detect prostate cancer in patients with prior negative transrectal prostate biopsy (TPB). MATERIAL AND METHODS:mpMRI (TSE-T2-w, DWI and DCE sequences) was performed on 1.5T (Magnetom Avanto; Siemens Healthcare Solutions) ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2014.07.001
更新日期：2015-03-01 00:00:00
abstract：:We report a case of necrotizing granulomatous vasculitis in the spermatic cord in a 35-year-old man with an antecedent of brain stroke 3 years before. The clinical manifestation was as a painless left scrotal mass. The diagnosis was established by histological examination of the spermatic cord. We discuss the physical...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73340-4
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVE:To analyze the incidence of urological complications, like fistula and stenosis in our series of 282 renal transplants and their management. MATERIALS AND METHODS:Between December 1995 and October 2005, 282 adult recipients underwent renal transplant. The most common urological complication was urinary fistu...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(06)73503-3
更新日期：2006-06-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:The aim of this study was to analyse prognostic impact of tumour histological grade on survival differences between primary G2 and G3 WHO1973 stage T1 tumours which were graded as HG according to WHO2004 grading system. MATERIALS AND METHODS:Data from 481 patients with primary T1HG bladder ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,多中心研究
doi：10.1016/j.acuro.2019.03.011
更新日期：2019-11-01 00:00:00
abstract：:Significant conceptual changes have taken place in renal tumoral diseases over the last few years. As a result of the authors' broad institutional experience, this overall revision describes the most up-to-date clinical and diagnostic aspects of this condition. Emphasis is made on molecular staging and two variables t...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(02)72825-8
更新日期：2002-09-01 00:00:00
abstract：:This article reviews the current status of the prostatic cryosurgery in the management of patients with prostate cancer. Recent advances in cryoablative technology have allowed to treat these patients successfully with decreased morbidity. Using transrectal high-resolution ultrasound imaging, prostate cryotherapy is d...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/s0210-4806(07)73627-6
更新日期：2007-03-01 00:00:00
abstract：PURPOSE:To evaluate the effect of JJ stents on SWL treatment of moderate (15-25mm) renal pelvic stones. MATERIALS AND METHODS:Between January 2016 and December 2017, a total of 152 adult patients who were planned to undergo SWL for a single radiopaque renal pelvic stone were included in the study. Patients with solita...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.acuro.2019.03.009
更新日期：2019-10-01 00:00:00
abstract：:Stones with different compositions respond differently to shock wave lithofragmentation. Likewise, the various lithotrity systems used may have different effects on the stones. To determine the relationships between stone composition and their fragmentation patterns, we conducted an in vitro study using endoscopy, mag...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：:Primary amyloidosis of the bladder is a rare disease entity manifested as extracellular deposits of a fibril protein in an amyloid substance form. Clinical presentation resembles a bladder tumor, as hematuria is the most common clinical manifestation. Single organ affectation is most frequent in the bladder, however, ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(01)72666-6
更新日期：2001-07-01 00:00:00
abstract：:Presentation of 11 cases of retroperitoneal sarcoma. Mean time from the beginning of symptoms to diagnosis is 6 months. The primary complementary study is CT. Surgery was performed in all cases, using complete resection in 6 cases, and partial resection in 5. Ten patients relapsed. 9 of which were treated with surgica...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：:Laparoscopic surgery is a surgical technique the urologist should add to his surgical armamentarium. Its performance tries to mimic the surgical phases of open surgery, and also its indications. Laparoscopic partial nephrectomy is a sophisticated technique that requires wide experience in the performance of endoscopic...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(06)73486-6
更新日期：2006-05-01 00:00:00
abstract：:We have performed experimental vasectomies in dogs in order to study effects of vas deferens ligature with close technique, on the testicular ultrastructure. We point out the existence of alterations: structural changes of the seminiferous epithelium, great extracellular spaces which are generated for the premature ex...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:We presented a case of inferior vena cava on the left side diagnosed by abdominal CT scan during the study of a renal cell carcinoma in the right side. This anomaly is very rare but it may suppose a more difficult approach to the nephrectomy. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/s0210-4806(05)73320-9
更新日期：2005-07-01 00:00:00
abstract：:The present job reviews the etiology, clinical presentation, diagnostic and treatment of interstitial cystitis. An exhaustive revision is made of all the possibilities of pharmacological treatment with a special mention to the two major drugs: dimethylsulfoxide and pentosampolysulphate. A critical judgement of existin...
journal_title：Actas urologicas espanolas
pub_type： 临床试验,杂志文章,随机对照试验,评审
doi：
更新日期：1990-05-01 00:00:00
abstract：CONTEXT:Interest in having alternatives in the treatment of benign prostate hyperplasia. OBJECTIVES:To assess the efficacy and safety of the Urolift® system for treating the symptoms of benign prostate hyperplasia. ACQUISITION OF EVIDENCE:Systematic review of the literature through searches on PubMed, Cochrane Librar...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章,评审
doi：10.1016/j.acuro.2014.05.010
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVE:To analyze the correlation between pathological data found in radical prostatectomy and previously performed biopsy in patients at low risk prostate cancer. MATERIAL AND METHODS:A descriptive, cross-sectional study was conducted to assess the characteristics of radical prostatectomies performed in our center...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2015.02.005
更新日期：2015-10-01 00:00:00
abstract：:Presentation of one case of penis-located multiple skin metastasis from prostate adenocarcinoma after hormonal blockade for 11 years. Revision and update of the topic, corroborating the poor prognosis of these patients. ...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:Bladder outlet obstruction with obstructive and irritative urinary symptoms may be a complication of surgery for female urinary incontinence. In presence of persistent symptoms, the therapy is surgical and usually consists in an accurate urethrolysis. The way of approach is generally transvaginal. In this pap...
journal_title：Actas urologicas espanolas
pub_type： 杂志文章
doi：10.1016/j.acuro.2011.07.021
更新日期：2012-06-01 00:00:00
