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Intrapleural streptokinase for the treatment of complicated parapneumonic effusion and empyema in 2 newborns.

Abstract：

:The management of complicated parapneumonic effusions by conventional first-line treatment with closed intercostal tube drainage and antibiotic therapy may fail because of thick viscous fluid and multiple pleural space loculations. Intrapleural fibrinolytic treatment is a non-invasive therapeutic option. In this report, we present successful use of intrapleural streptokinase for complicated parapneumonic effusion and empyema in 2 newborns. Intrapleural fibrinolytic therapy with streptokinase appears to be a safe and effective adjunctive therapy of choice and may have significant benefit even in newborns with complicated parapneumonic effusion and empyema, and thus, it can obviate surgical intervention.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Yigit AK,Yilmaz Y,Erdeve O,Gokce IK,Oguz SS,Uras N,Dilmen U

doi

10.1016/j.jpedsurg.2012.07.034

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

e41-4

issue

10

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(12)00547-7

journal_volume

47

pub_type

杂志文章

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