A novel test to differentiate anosmic malingerers from actually anosmic patients.

abstract：BACKGROUND:B-cell responses may play a role in the pathogenesis of nasal polyposis via local IgA and IgE production and activation of eosinophils and mast cells. B-cell attracting chemokines may therefore have relevance in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNPs) Methods: Polyp and inferio...

journal_title：American journal of rhinology & allergy

authors： Patadia M,Dixon J,Conley D,Chandra R,Peters A,Suh LA,Kato A,Carter R,Harris K,Grammer L,Kern R,Schleimer R

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The management of allergic rhinitis (AR) encompasses education, pharmacotherapy, immunotherapy, and surgery. FK506 (tacrolimus) is an immunosuppressant that inhibits allergic reactions. The purpose of this study was to reveal whether FK506 treatment reduces allergic inflammation in an AR mouse model and to ...

journal_title：American journal of rhinology & allergy

authors： Shin JH,Park HR,Kim SW,Park CS,Cho JH,Park YJ,Kim SW

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Endoscopic skull base surgery (ESBS) provides a safe, minimally invasive approach to treat benign and malignant skull base lesions. The significance of concomitant sinonasal pathology on imaging in patients undergoing ESBS and its effect on perioperative management is not well described. We sought to ident...

journal_title：American journal of rhinology & allergy

authors： Shah J,Cappello ZJ,Roxbury C,Tang D,Woodard TD,Kshettry VR,Recinos PF,Sindwani R

更新日期：2020-08-11 00:00:00

abstract：BACKGROUND:The goal of endoscopic sinus surgery in chronic sinusitis is to create good drainage of the paranasal sinuses. Metal stents used to prevent lateralization of the middle concha are associated with adverse effects. OBJECTIVE:The aim of this experimental study was to evaluate the feasibility and safety of a ne...

journal_title：American journal of rhinology & allergy

authors： Yaniv D,Shlosberg L,Flomenblit J,Frenklach G,Rath-Wolfson L,Yaniv E

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Concerns over radiation exposure with paranasal sinus computed tomography (CT) have recently evolved. Magnetic resonance imaging (MRI) may be more advantageous in this regard, but the diagnostic assessment of MRI in chronic rhinosinusitis (CRS) has not been reported. The purpose of this study was to determin...

journal_title：American journal of rhinology & allergy

authors： Lin HW,Bhattacharyya N

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Chronic rhinitis impacts 60 million Americans and is associated with significant costs for patients. Although medical treatments are first line, some patients require surgical intervention such as vidian or posterial nasal neurectomy. Previous reviews have investigated the role of surgical management in chro...

journal_title：American journal of rhinology & allergy

authors： Kompelli AR,Janz TA,Rowan NR,Nguyen SA,Soler ZM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Nasal polyposis represents the end point of multiple inflammatory pathways and controversy continues as to the exact roles of medical and surgical approaches in the management of nasal polyposis. METHODS:A combination of both is often required to manage polyps adequately with surgery and intranasal steroids...

journal_title：American journal of rhinology & allergy

authors： Aouad RK,Chiu AG

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To evaluate the role of allergen immunotherapy (AIT) in the treatment of allergic rhinitis (AR). METHOD:Individual studies, systematic reviews, and practice guidelines that included information on sublingual AIT (SLIT) and subcutaneous AIT (SCIT) in the treatment of AR were considered. RESULTS:AIT via the SLI...

journal_title：American journal of rhinology & allergy

authors： Cox L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Smoking status has been established as a known irritant of the upper and lower respiratory tracts, leading to inflammation throughout the respiratory system. Tobacco smoking is one comorbidity encountered among chronic rhinosinusitis (CRS) patients. The histopathologic features of CRS and comorbid smoking st...

journal_title：American journal of rhinology & allergy

authors： Kuhar HN,Ganti A,Brown HJ,Gattuso P,Ghai R,Mahdavinia M,Batra PS,Tajudeen BA

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The current otolaryngologic literature is lacking in basic science investigation regarding endoscopic anterior ethmoid artery (AEA) ligation as part of the armamentarium for epistaxis control. This investigation provides the anatomic rationale for endoscopic ligation of the AEA in the surgical treatment of e...

journal_title：American journal of rhinology & allergy

authors： Camp AA,Dutton JM,Caldarelli DD

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:This study was designed to determine whether there is any correlation between results of the skin-prick test and the severity of symptoms in allergic rhinitis. METHODS:We retrospectively evaluated 150 patients with persistent or intermittent allergic rhinitis confirmed by positive skin tests and scaled fro...

journal_title：American journal of rhinology & allergy

authors： Tatar EC,Sürenoğlu UA,Saylam G,Işık E,Ozdek A,Korkmaz H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure (CSE) results in extensive inflammation in the upper and lower airways. Reactive oxygen species, such as superoxide, have been shown to be potent mediators of this inflammation. METHODS:Mucosal biopsy specimens were collected from patients undergoing sinonasal surgery and were used ...

journal_title：American journal of rhinology & allergy

authors： Mulligan RM,Atkinson C,Vertegel AA,Reukov V,Schlosser RJ

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:This study evaluates if there is any benefit of adding epinephrine to lidocaine in patients undergoing diagnostic rigid nasal endoscopy. A prospective, randomized, double-blinded study was performed. METHODS:Seventy patients were randomized to receive either 2% lidocaine or 2% lidocaine with 0.2% epinephrin...

journal_title：American journal of rhinology & allergy

authors： Al-Qudah M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Prominent expression of YKL-40 has been associated with pathological conditions characterized by tissue remodeling. We determined the expression level and distribution pattern of YKL-40 in allergic nasal mucosa and evaluated the effect of YKL-40 on the proliferation and migration of fibroblasts, the producti...

journal_title：American journal of rhinology & allergy

authors： Park SJ,Jun YJ,Kim TH,Jung JY,Hwang GH,Jung KJ,Lee SH,Lee HM,Lee SH

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Ginseng (Panax ginseng C.A. Meyer) has been used in Asian countries for the treatment of various diseases. However, the mechanisms of liquid Panax ginseng (LG) on allergic inflammatory response in epidermal growth factor (EGF)-stimulated human airway epithelial cells remain largely unclear. METHODS:MUC5AC, ...

journal_title：American journal of rhinology & allergy

authors： Kim JH,Kang JW,Kim M,Lee DH,Kim H,Choi HS,Kim EJ,Chung IM,Chung IY,Yoon DY

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Although not so common, septoplasty carries the risk of inducing nasal deformity such as saddle nose and deviated nose. Surgical correction for those deformities is a formidable task to deal with, because the septal cartilage framework was already weakened due to previous procedure. This study was designed t...

journal_title：American journal of rhinology & allergy

authors： Yeo NK,Jang YJ

更新日期：2009-09-01 00:00:00

abstract：BACKGROUNDS:Diagnosis of allergic fungal rhinosinusitis (AFRS) is complicated because of the presence of fungi on mucosal surfaces of sinonasal passages. The objectives of this study were to define, using immunohistochemistry, lymphocyte populations associated with noninvasive fungal-related chronic rhinosinusitis (CRS...

journal_title：American journal of rhinology & allergy

authors： Ragab A,Samaka RM

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Patients who suffer from hyposmia and anosmia report a negative effect on their overall quality of life. Smell disturbance of patients with chronic rhinosinusitis (CRS) can improve after endoscopic sinus surgery (ESS). Although several studies have shown that 50-83% of patients may notice an improvement in o...

journal_title：American journal of rhinology & allergy

authors： Hsu CY,Wang YP,Shen PH,Weitzel EK,Lai JT,Wormald PJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The impact of middle turbinate resection (MTR) on olfaction remains a point of debate in the current literature. Few studies have objectively evaluated olfactory cleft airflow following MTR; thus, the mechanism by which MTR may impact olfaction is poorly understood. It is not known whether the postsurgical c...

journal_title：American journal of rhinology & allergy

authors： Alam S,Li C,Bradburn KH,Zhao K,Lee TS

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Viral respiratory tract infections are associated with a significant burden of disease and represent one of the leading causes of mortality worldwide. The current Coronavirus Disease 2019 (COVID-19) pandemic highlights the devastating toll that respiratory viruses have on humanity and the desperate need to u...

journal_title：American journal of rhinology & allergy

authors： Yuen E,Gudis DA,Rowan NR,Nguyen SA,Schlosser RJ

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis (AR). We determined the distribution of aeroallergens, detected by skin-prick tests (SPT), in adult patients with AR in the Eastern Black Sea re...

journal_title：American journal of rhinology & allergy

authors： Coskun ZO,Erdivanlı OC,Kazıkdas KÇ,Terzi S,Sahin U,Ozgur A,Demirci M,Dursun E,Cingi C

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Fibrinolytic components, their receptors, and inhibitors are considered to play an important role in inflammation and tissue remodeling including chronic rhinosinusitis (CRS). To clarify the relationship between these components and the pathology of CRS, we analyzed fibrinolytic components in sinonasal mucos...

journal_title：American journal of rhinology & allergy

authors： Sejima T,Holtappels G,Bachert C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Gelsolin is an actin-binding protein with multiple cellular functions including apoptosis and is reported to be down-regulated in various cancers and premalignant lesions. The objective of this study was to identify gelsolin and caspase-3 expression in inverted papilloma (IP) and investigate the role of gels...

journal_title：American journal of rhinology & allergy

authors： Cho JE,Park Wi,Kim DC,Kim HJ,Kim SW,Kang JM,Cho JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Conclusive evidence exists that biofilms are present on the mucosa of chronic rhinosinusitis (CRS) patients. Less is known about the species constituting these biofilms. This study developed a fluorescence in situ hybridization (FISH) protocol for characterization of bacterial and fungal biofilms in CRS. ME...

journal_title：American journal of rhinology & allergy

authors： Foreman A,Psaltis AJ,Tan LW,Wormald PJ

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Local allergic rhinitis (LAR) has been observed in patients without atopy. However, LAR is still underdiagnosed in patients with perennial or seasonal nasal symptoms. OBJECTIVE:The aim of this study was to determine the prevalence of LAR in young patients with a previous diagnosis of nonallergic rhinitis or...

journal_title：American journal of rhinology & allergy

authors： Krajewska-Wojtys A,Jarzab J,Gawlik R,Bozek A

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:A number of studies suggested that limited economical airborne allergy screening can successfully predict true respiratory allergy and be of use to primary care providers (PCPs) in improving the accuracy of their differential diagnosis and treatment of allergic rhinitis. More accurate diagnosis would lead to...

journal_title：American journal of rhinology & allergy

authors： Mansfield L,Hutteman HR,Tyson S,Enriquez A

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and asthma are strongly associated, and patients suffering from both diseases are often difficult to treat. However, no guidelines about the management of patients with CRS and coexisting asthma exist. OBJECTIVE:The purpose of this systematic review wa...

journal_title：American journal of rhinology & allergy

authors： Rix I,Håkansson K,Larsen CG,Frendø M,von Buchwald C

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:A 10- to 15-mm L-strut in the dorsal and caudal areas of the nasal septum is preserved during septoplasty to maintain structural stability and prevent external deformity. However, during endoscopically performed septoplasty the surgeon has a very different perspective, which may create a more challenging sit...

journal_title：American journal of rhinology & allergy

authors： Seth R,Haffey T,McBride JM,Sindwani R

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Volumetric analysis of the olfactory cleft by using computed tomography has been associated with olfaction in patients with chronic rhinosinusitis (CRS). However, existing studies have not comprehensively measured olfaction, and it thus remains unknown whether correlations differ across specific dimensions o...

journal_title：American journal of rhinology & allergy

authors： Kohli P,Schlosser RJ,Storck K,Soler ZM

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Laryngeal edema is a life-threatening manifestation of hereditary angioedema (HAE), an autosomal-dominant disorder caused by quantitative or functional C1 esterase inhibitor (C1 INH) deficiency. The preparation of nanofiltered C1 INH (C1 INH-nf) used in this study is indicated for routine prophylaxis against...

journal_title：American journal of rhinology & allergy

authors： Riedl MA,Lumry WR,Li HH,Craig TJ,Fitts D,Kalfus I,Uknis ME

更新日期：2013-11-01 00:00:00