Local allergic rhinitis to pollens is underdiagnosed in young patients.

Abstract:

BACKGROUND:Local allergic rhinitis (LAR) has been observed in patients without atopy. However, LAR is still underdiagnosed in patients with perennial or seasonal nasal symptoms. OBJECTIVE:The aim of this study was to determine the prevalence of LAR in young patients with a previous diagnosis of nonallergic rhinitis or suspicion of allergy. METHODS:A total of 121 patients, ages 12-18 years old, with confirmed nonallergic rhinitis and typical seasonal nasal symptoms were examined. Skin-prick tests; serum and nasal specific immunoglobulin E (IgE) measurements; and nasal provocation tests by using grass (Phleum partense), Artemisia, and birch pollens were performed. A control group of age-matched patients with a diagnosis of seasonal allergic rhinitis underwent the same procedures as the test group. RESULTS:LAR to grass pollen (P. partense), Artemisia, and birch was confirmed in 17 (16.6%), 6 (5.9%), and 9 (8.9%) of patients, respectively. Polyvalent allergy was established in 21 subjects (20.8%): grass and Artemisia, 11 patients (10.9%); and grass and birch, 10 patients (9.9%). The remaining 48 patients (47.5%) were diagnosed with nonallergic rhinitis. The results of the nasal provocation tests and the concentrations of nasal IgE were similar among the analyzed groups. Furthermore, the concentration of nasal IgE increased faster in patients with LAR than in patients with allergic rhinitis; however, this difference was not statistically significant. CONCLUSION:LAR is a serious problem in young patients; however, its significance is still unappreciated.

journal_name

Am J Rhinol Allergy

authors

Krajewska-Wojtys A,Jarzab J,Gawlik R,Bozek A

doi

10.2500/ajra.2016.30.4369

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

198-201

issue

6

eissn

1945-8924

issn

1945-8932

journal_volume

30

pub_type

杂志文章
  • Intranasal landmarks for adequate L-strut preservation during endoscopic septoplasty.

    abstract:BACKGROUND:A 10- to 15-mm L-strut in the dorsal and caudal areas of the nasal septum is preserved during septoplasty to maintain structural stability and prevent external deformity. However, during endoscopically performed septoplasty the surgeon has a very different perspective, which may create a more challenging sit...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2014.28.4042

    authors: Seth R,Haffey T,McBride JM,Sindwani R

    更新日期:2014-05-01 00:00:00

  • Dupilumab as Add-on Therapy for Chronic Rhinosinusitis With Nasal Polyposis in Aspirin Exacerbated Respiratory Disease.

    abstract:BACKGROUND:Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life. OBJECTIVE:Our objective was to evaluate the efficacy of dupilumab in AERD patients with uncontrolled, chronic rhinosinusitis with n...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.1177/1945892420961969

    authors: Mustafa SS,Vadamalai K,Scott B,Ramsey A

    更新日期:2020-09-23 00:00:00

  • Efficacy of preoperative itraconazole in allergic fungal rhinosinusitis.

    abstract:INTRODUCTION:Criterion standard treatment of allergic fungal sinusitis (AFS) is primary surgery followed by adjuvant therapy. Even after good surgery, recurrence rates vary from 10 to 79%. Antifungals, e.g., itraconazole, and steroids have shown varying success rates in delaying recurrences given after surgery. Itracon...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.2500/ajra.2015.29.4187

    authors: Patro SK,Verma RK,Panda NK,Chakrabarti A,Singh P

    更新日期:2015-07-01 00:00:00

  • Comparison between endoscopic and external dacryocystorhinostomy by using the Lacrimal Symptom Questionnaire: A pilot study.

    abstract:BACKGROUND:Epiphora has a significant impact on the patient's quality of life and is commonly caused by nasolacrimal duct obstruction. Dacryocystorhinostomy (DCR) has traditionally been performed via an external approach, which involves a skin incision. With the advent of endoscopes, the endonasal approach to DCR has g...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2018.32.4494

    authors: Wong WK,Dean S,Nair S

    更新日期:2018-01-01 00:00:00

  • Reliability of basophil activation test using CD203c expression in diagnosis of pollen allergy.

    abstract:BACKGROUND:CD203c is a basophil surface marker and its expression is rapidly up-regulated after cross-linking of high-affinity immunoglobulin E (IgE) receptor (FcepsilonR1) by an allergen. CD203c basophil activation tests have been studied for the in vitro diagnosis of several allergic conditions. However, there is li...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2011.25.3723

    authors: Özdemir SK,Güloğlu D,Sin BA,Elhan AH,Ikincioğulları A,Mısırlıgil Z

    更新日期:2011-11-01 00:00:00

  • Efficacy and safety of bupivacaine versus lidocaine in local anesthesia of the nasopharynx: A meta-analysis.

    abstract:PURPOSE:To assess the efficacy and safety of bupivacaine compared with lidocaine in local anesthesia of nasopharynx through meta-analysis. METHODS:A number of medical literature data bases were searched electronically. Relevant journals and references of included studies were manually searched. Two reviewers independe...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,meta分析

    doi:10.2500/ajra.2016.30.4357

    authors: Yu X,Wang J,Huang L,Yu X,He Z

    更新日期:2016-09-30 00:00:00

  • HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease.

    abstract:BACKGROUND:Major histocompatibility complex (MHC) class II is involved in T-cell activation, cytokine secretion, and induction of immune responses. Cytokines, staphylococcus super antigens, and eosinophil activation are proposed to play important roles in aspirin-exacerbated respiratory disease (AERD). OBJECTIVES:This...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2015.29.4154

    authors: Esmaeilzadeh H,Nabavi M,Amirzargar AA,Aryan Z,Arshi S,Bemanian MH,Fallahpour M,Mortazavi N,Rezaei N

    更新日期:2015-05-01 00:00:00

  • Major symptom score utility index for patients with acute rhinosinusitis.

    abstract:BACKGROUND:Evaluation of acute rhinosinusitis treatment effectiveness is based on patient-reported relief of symptoms. This study was designed to develop a multiattribute utility scoring algorithm for the Major Symptom Score (MSS) and secondarily to evaluate the psychometric characteristics (i.e., validity and responsi...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2011.25.3575

    authors: Revicki DA,Margolis MK,Thompson CL,Meltzer EO,Sandor DW,Shaw JW

    更新日期:2011-05-01 00:00:00

  • Characterization of specific antibody deficiency in adults with medically refractory chronic rhinosinusitis.

    abstract:BACKGROUND:Specific antibody deficiency may predispose patients to recurrent respiratory tract infections. There is limited literature assessing specific antibody deficiency in chronic rhinosinusitis (CRS). This study evaluated the role of specific antibody deficiency in patients with CRS who have failed medical therap...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2011.25.3653

    authors: Carr TF,Koterba AP,Chandra R,Grammer LC,Conley DB,Harris KE,Kern R,Schleimer RP,Peters AT

    更新日期:2011-07-01 00:00:00

  • Differences in initial immunoprofiles between recurrent and nonrecurrent chronic rhinosinusitis with nasal polyps.

    abstract:BACKGROUND:Surgery for chronic rhinosinusitis with nasal polyps (CRSwNPs) often fails because of recurrence of disease. So far, we do not know if specific cytokine profiles are linked to recurrence after functional endoscopic sinus surgery (FESS) or can predict recurrence. In this study we investigate the cytokine prof...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2014.28.4033

    authors: Van Zele T,Holtappels G,Gevaert P,Bachert C

    更新日期:2014-05-01 00:00:00

  • Clinical considerations in the use of sublingual immunotherapy for allergic rhinitis.

    abstract:BACKGROUND:Allergen immunotherapy (AIT) has been in practice for more than 100 years. However, research in novel routes and delivery methods of immunotherapy to treat allergic rhinitis (AR) and conjunctivitis has only recently occurred in the United States, where the predominant form of AIT provided is largely via a su...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,评审

    doi:10.2500/ajra.2015.29.4148

    authors: Lee S,Nolte H,Benninger MS

    更新日期:2015-03-01 00:00:00

  • High sensitization to house-dust mites in patients with allergic rhinitis in the eastern Black Sea region of Turkey: A retrospective study.

    abstract:OBJECTIVES:Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis (AR). We determined the distribution of aeroallergens, detected by skin-prick tests (SPT), in adult patients with AR in the Eastern Black Sea re...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2016.30.4353

    authors: Coskun ZO,Erdivanlı OC,Kazıkdas KÇ,Terzi S,Sahin U,Ozgur A,Demirci M,Dursun E,Cingi C

    更新日期:2016-09-01 00:00:00

  • Diagnostic and staging accuracy of magnetic resonance imaging for the assessment of sinonasal disease.

    abstract:BACKGROUND:Concerns over radiation exposure with paranasal sinus computed tomography (CT) have recently evolved. Magnetic resonance imaging (MRI) may be more advantageous in this regard, but the diagnostic assessment of MRI in chronic rhinosinusitis (CRS) has not been reported. The purpose of this study was to determin...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.2500/ajra.2009.23.3260

    authors: Lin HW,Bhattacharyya N

    更新日期:2009-01-01 00:00:00

  • Practice Patterns in Office-Based Rhinology: Survey of the American Rhinologic Society.

    abstract:BACKGROUND:Recent years have witnessed significant expansion in office-based rhinology. This study assesses practice patterns of the American Rhinologic Society (ARS) membership regarding office-based rhinologic procedures. METHODS:A 24-item survey was disseminated to the ARS membership from March 15 to May 31, 2016. ...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.1177/1945892418804904

    authors: Lee JT,DelGaudio J,Orlandi RR

    更新日期:2019-01-01 00:00:00

  • Monoclonal antibody therapy in sinonasal disease.

    abstract::Chronic rhinosinusitis (CRS) affects 12.5% of the U.S. POPULATION:CRS can be divided into CRS with nasal polyps (CRSwNP) and CRS without nasal polyps. Some individuals with CRSwNP do not respond to standard-of-care medical and surgical management. For these individuals, targeted biologic agents are emerging as an imp...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,评审

    doi:10.2500/ajra.2017.31.4412

    authors: Chiarella SE,Sy H,Peters AT

    更新日期:2017-03-01 00:00:00

  • Protein microarray analysis of nasal polyps from aspirin-sensitive and aspirin-tolerant patients with chronic rhinosinusitis.

    abstract:BACKGROUND:The purpose of this study was to apply protein microarray technology to the study of sinonasal tissue and to identify differential protein expression in nasal polyps from aspirin-sensitive (AS) versus aspirin-tolerant (AT) patients with chronic rhinosinusitis (CRS) and CRS with nasal polyps (CRSwNPs). METHO...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2009.23.3314

    authors: Zander KA,Saavedra MT,West J,Scapa V,Sanders L,Kingdom TT

    更新日期:2009-05-01 00:00:00

  • Immunohistochemical dissimilarity between allergic fungal and nonfungal chronic rhinosinusitis.

    abstract:BACKGROUNDS:Diagnosis of allergic fungal rhinosinusitis (AFRS) is complicated because of the presence of fungi on mucosal surfaces of sinonasal passages. The objectives of this study were to define, using immunohistochemistry, lymphocyte populations associated with noninvasive fungal-related chronic rhinosinusitis (CRS...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2013.27.3882

    authors: Ragab A,Samaka RM

    更新日期:2013-05-01 00:00:00

  • The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis.

    abstract:BACKGROUND:The management of allergic rhinitis (AR) encompasses education, pharmacotherapy, immunotherapy, and surgery. FK506 (tacrolimus) is an immunosuppressant that inhibits allergic reactions. The purpose of this study was to reveal whether FK506 treatment reduces allergic inflammation in an AR mouse model and to ...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2012.26.3743

    authors: Shin JH,Park HR,Kim SW,Park CS,Cho JH,Park YJ,Kim SW

    更新日期:2012-03-01 00:00:00

  • The feasibility of 18F-fluorodeoxyglucose-positron emission tomography uptake as a prognostic factor for paranasal sinus malignancy.

    abstract:BACKGROUND:There is a correlation between (18)F-fluorodeoxyglucose (FDG) uptake and the level of intracellular metabolic tumor activity, which in turn may be associated with active proliferation, invasion, and prognosis as well as distant metastases in head and neck cancer. This study was designed to assess whether tum...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2013.27.3848

    authors: Seol JH,Kim J,Lee JD,Lee JG,Yoon JH,Kim CH

    更新日期:2013-03-01 00:00:00

  • Olfactory cleft computed tomography analysis and olfaction in chronic rhinosinusitis.

    abstract:BACKGROUND:Volumetric analysis of the olfactory cleft by using computed tomography has been associated with olfaction in patients with chronic rhinosinusitis (CRS). However, existing studies have not comprehensively measured olfaction, and it thus remains unknown whether correlations differ across specific dimensions o...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2016.30.4365

    authors: Kohli P,Schlosser RJ,Storck K,Soler ZM

    更新日期:2016-11-01 00:00:00

  • State of the art treatment of nasal polyposis.

    abstract:BACKGROUND:Nasal polyposis represents the end point of multiple inflammatory pathways and controversy continues as to the exact roles of medical and surgical approaches in the management of nasal polyposis. METHODS:A combination of both is often required to manage polyps adequately with surgery and intranasal steroids...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,评审

    doi:10.2500/ajra.2011.25.3681

    authors: Aouad RK,Chiu AG

    更新日期:2011-09-01 00:00:00

  • A comparison of the psychometric properties of the Mini-Rhinitis Quality of Life Questionnaire and the Rhinitis Control Assessment Test.

    abstract:BACKGROUND:The relationships between validated quality of life tools and control tools have not been explored for rhinitis. This study was designed to determine relationships of the Mini-Rhinitis Quality of Life Questionnaire (MiniRQLQ) and the Rhinitis Control Assessment Test (RCAT) to each other regarding content an...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2012.26.3744

    authors: Schatz M,Zeiger RS,Chen W,Yang SJ,Stanford RH,Garris CP

    更新日期:2012-03-01 00:00:00

  • Grass pollen sublingual immunotherapy: a double-blind, placebo-controlled study in elderly patients with seasonal allergic rhinitis.

    abstract:BACKGROUND:This study evaluates the safety and efficacy of specific sublingual immunotherapy (SLIT) against grass pollen allergens in patients >60 years of age with seasonal allergic rhinitis (SAR) and/or asthma. This study sought to assess nasal symptoms during the grass pollen season, reduce medication use, and monit...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.2500/ajra.2014.28.4091

    authors: Bozek A,Kolodziejczyk K,Warkocka-Szoltysek B,Jarzab J

    更新日期:2014-09-01 00:00:00

  • Sinonasal T2R-mediated nitric oxide production in response to Bacillus cereus.

    abstract:BACKGROUND:Upper airway epithelial cells produce bactericidal nitric oxide (NO) in response to both gram-positive and gram-negative bacteria. Our previous work demonstrated that T2R38, a bitter taste receptor (T2R) expressed in airway epithelium, produces NO in response to quorum-sensing molecules secreted by Pseudomon...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2017.31.4453

    authors: Carey RM,Workman AD,Yan CH,Chen B,Adappa ND,Palmer JN,Kennedy DW,Lee RJ,Cohen NA

    更新日期:2017-07-01 00:00:00

  • Characterization of bacterial and fungal biofilms in chronic rhinosinusitis.

    abstract:BACKGROUND:Conclusive evidence exists that biofilms are present on the mucosa of chronic rhinosinusitis (CRS) patients. Less is known about the species constituting these biofilms. This study developed a fluorescence in situ hybridization (FISH) protocol for characterization of bacterial and fungal biofilms in CRS. ME...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2009.23.3413

    authors: Foreman A,Psaltis AJ,Tan LW,Wormald PJ

    更新日期:2009-11-01 00:00:00

  • Efficacy of lidocaine with or without epinephrine in rigid nasal endoscopy.

    abstract:BACKGROUND:This study evaluates if there is any benefit of adding epinephrine to lidocaine in patients undergoing diagnostic rigid nasal endoscopy. A prospective, randomized, double-blinded study was performed. METHODS:Seventy patients were randomized to receive either 2% lidocaine or 2% lidocaine with 0.2% epinephrin...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.2500/ajra.2014.28.4110

    authors: Al-Qudah M

    更新日期:2014-11-01 00:00:00

  • Association of pediatric allergic rhinitis with the ratings of attention-deficit/hyperactivity disorder.

    abstract:BACKGROUND:Allergic rhinitis (AR) is currently the most prevalent allergic disease in children and adolescents. OBJECTIVE:Surveys conducted by population-based studies of East Asia revealed an increased prevalence of behavioral disorders in patients with AR. Thus, in this study, we explored the prevalence of attention...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2017.31.4439

    authors: Feng B,Jin H,Xiang H,Li B,Zheng X,Chen R,Shi Y,Chen S,Chen B

    更新日期:2017-05-01 00:00:00

  • The seasonality of respiratory viruses in patients with chronic rhinosinusitis.

    abstract:BACKGROUND:Chronic rhinosinusitis (CRS) is a common illness, yet little is known about its pathogenesis, including the role played by respiratory viruses. METHODS:A transversal prospective study was conducted to analyze the seasonality of CRS using real-time polymerase chain reaction to detect respiratory virus genome...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章

    doi:10.2500/ajra.2015.29.4129

    authors: Lima JT,Paula FE,Proença-Modena JL,Demarco RC,Buzatto GP,Saturno TH,Delcaro LS,Tamashiro E,Valera FC,Arruda E,Anselmo-Lima WT

    更新日期:2015-01-01 00:00:00

  • Viral Infections of the Upper Airway in the Setting of COVID-19: A Primer for Rhinologists.

    abstract:BACKGROUND:Viral respiratory tract infections are associated with a significant burden of disease and represent one of the leading causes of mortality worldwide. The current Coronavirus Disease 2019 (COVID-19) pandemic highlights the devastating toll that respiratory viruses have on humanity and the desperate need to u...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,评审

    doi:10.1177/1945892420947929

    authors: Yuen E,Gudis DA,Rowan NR,Nguyen SA,Schlosser RJ

    更新日期:2021-01-01 00:00:00

  • The radiologic evaluation of osteitis type and formation in chronic rhinosinusitis with and without nasal polyposis.

    abstract:OBJECTIVE:To evaluate the amount and type of osteitis observed in chronic rhinosinusitis with nasal polyposis (CRSwNP) and compare it with that of chronic rhinosinusitis without nasal polyposis (CRSnNP). SETTING:Sisli Etfal Research and Education Hospital, Istanbul, Turkey. STUDY DESIGN:Prospective, single-blind, coh...

    journal_title:American journal of rhinology & allergy

    pub_type: 杂志文章,随机对照试验

    doi:10.2500/ajra.2015.29.4240

    authors: Emre IE,Celebi I,Ercan I

    更新日期:2015-11-01 00:00:00