The effect of topical FK506 (tacrolimus) in a mouse model of allergic rhinitis.

abstract：BACKGROUND:Biofilm formation has been implicated as an etiologic factor in the development of chronic rhinosinusitis (CRS). Nasal irrigation with surfactants including dilute baby shampoo have been proposed as an antibiofilm treatment for CRS patients. The effect of dilute baby shampoo on normal sinonasal mucosal funct...

journal_title：American journal of rhinology & allergy

authors： Isaacs S,Fakhri S,Luong A,Whited C,Citardi MJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:This study evaluates the safety and efficacy of specific sublingual immunotherapy (SLIT) against grass pollen allergens in patients >60 years of age with seasonal allergic rhinitis (SAR) and/or asthma. This study sought to assess nasal symptoms during the grass pollen season, reduce medication use, and monit...

journal_title：American journal of rhinology & allergy

authors： Bozek A,Kolodziejczyk K,Warkocka-Szoltysek B,Jarzab J

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) of the paranasal sinuses is the diagnostic reference standard for chronic rhinosinusitis and related inflammatory sinus pathology. Nasal nitric oxide (nNO) levels have been investigated as a diagnostic tool in sinus disease because it decreases with sinus obstruction. OBJECTIVE:The ...

journal_title：American journal of rhinology & allergy

authors： Oliver JD,Lim KG,O'Brien EK

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a common illness, yet little is known about its pathogenesis, including the role played by respiratory viruses. METHODS:A transversal prospective study was conducted to analyze the seasonality of CRS using real-time polymerase chain reaction to detect respiratory virus genome...

journal_title：American journal of rhinology & allergy

authors： Lima JT,Paula FE,Proença-Modena JL,Demarco RC,Buzatto GP,Saturno TH,Delcaro LS,Tamashiro E,Valera FC,Arruda E,Anselmo-Lima WT

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Local allergic rhinitis (LAR) has been observed in patients without atopy. However, LAR is still underdiagnosed in patients with perennial or seasonal nasal symptoms. OBJECTIVE:The aim of this study was to determine the prevalence of LAR in young patients with a previous diagnosis of nonallergic rhinitis or...

journal_title：American journal of rhinology & allergy

authors： Krajewska-Wojtys A,Jarzab J,Gawlik R,Bozek A

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Patients report nasal congestion as the most bothersome seasonal allergic rhinitis (SAR) symptom. Measurement of this symptom in previous research has largely been based on subjective patient ratings. This study was designed to measure efficacy, onset, and duration of action of the corticosteroid mometasone ...

journal_title：American journal of rhinology & allergy

authors： Salapatek AM,Patel P,Gopalan G,Varghese ST

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The effect of crenotherapy on major mucosal markers of inflammation, TNF alpha, human beta-defensins 2 (hBD-2), and calprotectin, are largely unexplored in pediatric chronic rhinosinusitis (CRS). The aim of this study was to investigate the effects of crenotherapy with sulfate-sodium-chloride water on mucos...

journal_title：American journal of rhinology & allergy

authors： Passariello A,Di Costanzo M,Terrin G,Iannotti A,Buono P,Balestrieri U,Balestrieri G,Ascione E,Pedata M,Canani FB,Canani RB

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Smoking status has been established as a known irritant of the upper and lower respiratory tracts, leading to inflammation throughout the respiratory system. Tobacco smoking is one comorbidity encountered among chronic rhinosinusitis (CRS) patients. The histopathologic features of CRS and comorbid smoking st...

journal_title：American journal of rhinology & allergy

authors： Kuhar HN,Ganti A,Brown HJ,Gattuso P,Ghai R,Mahdavinia M,Batra PS,Tajudeen BA

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Gelsolin is an actin-binding protein with multiple cellular functions including apoptosis and is reported to be down-regulated in various cancers and premalignant lesions. The objective of this study was to identify gelsolin and caspase-3 expression in inverted papilloma (IP) and investigate the role of gels...

journal_title：American journal of rhinology & allergy

authors： Cho JE,Park Wi,Kim DC,Kim HJ,Kim SW,Kang JM,Cho JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Spontaneous cerebrospinal fluid (CSF) leaks are largely attributed to idiopathic intracranial hypertension and typically present as skull base defects with or without prolapse of intracranial contents. However, in our practice, we have encountered a distinct type of spontaneous CSF leak that presents in a di...

journal_title：American journal of rhinology & allergy

authors： Loftus PA,Wise SK,Daraei P,Baugnon K,DelGaudio JM

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Surgery for chronic rhinosinusitis with nasal polyps (CRSwNPs) often fails because of recurrence of disease. So far, we do not know if specific cytokine profiles are linked to recurrence after functional endoscopic sinus surgery (FESS) or can predict recurrence. In this study we investigate the cytokine prof...

journal_title：American journal of rhinology & allergy

authors： Van Zele T,Holtappels G,Gevaert P,Bachert C

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Silastic splints have been used as effective tools for septal support, avoiding adhesion, and mucosal healing after septal surgery. Furthermore, although many surgeons insert septal splints, no well-designed trials exist to support their use. A randomized double-blinded controlled trial was performed. METHO...

journal_title：American journal of rhinology & allergy

authors： Jung YG,Hong JW,Eun YG,Kim MG

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Although nasal peak flow measurements have been proposed as a simple alternative method to assess nasal patency, which of nasal peak expiratory flow or nasal peak inspiratory flow (NPEF/NPIF) or the peak expiratory flow index or peak inspiratory flow index (PEFI/PIFI; the ratios between nasal and oral PEF or...

journal_title：American journal of rhinology & allergy

authors： Kirtsreesakul V,Leelapong J,Ruttanaphol S

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis (AR). We determined the distribution of aeroallergens, detected by skin-prick tests (SPT), in adult patients with AR in the Eastern Black Sea re...

journal_title：American journal of rhinology & allergy

authors： Coskun ZO,Erdivanlı OC,Kazıkdas KÇ,Terzi S,Sahin U,Ozgur A,Demirci M,Dursun E,Cingi C

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Assessing surgical competency in otolaryngology is challenging, and residency programs are now responsible for ensuring the surgical competency of their graduates. Therefore, more objective assessment tools are being incorporated into the evaluation process. Objective structured assessment of technical skill...

journal_title：American journal of rhinology & allergy

authors： Obeid AA,Al-Qahtani KH,Ashraf M,Alghamdi FR,Marglani O,Alherabi A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:This study reports the combined experience of the University of Miami and University of Pittsburgh with endoscopic endonasal resection of esthesioneuroblastoma (ENB). A retrospective case series review was performed in a tertiary care university hospital. METHODS:Twenty-three patients, 16 men and 7 women, w...

journal_title：American journal of rhinology & allergy

authors： Folbe A,Herzallah I,Duvvuri U,Bublik M,Sargi Z,Snyderman CH,Carrau R,Casiano R,Kassam AB,Morcos JJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Respiratory epithelial adenomatoid hamartomas (REAH) are benign nose neoplasms found in the nasal cavity and sinuses. Symptoms include anosmia, nasal obstruction, facial pressure, and rhinorrhea. Although previously thought to be rare, these tumors are being increasingly recognized on pathology in patients u...

journal_title：American journal of rhinology & allergy

authors： Davison WL,Pearlman AN,Donatelli LA,Conley LM

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:To assess the efficacy and safety of bupivacaine compared with lidocaine in local anesthesia of nasopharynx through meta-analysis. METHODS:A number of medical literature data bases were searched electronically. Relevant journals and references of included studies were manually searched. Two reviewers independe...

journal_title：American journal of rhinology & allergy

authors： Yu X,Wang J,Huang L,Yu X,He Z

更新日期：2016-09-30 00:00:00

abstract：BACKGROUND:MUC5AC, a major secreted mucin, is increased in chronic inflammatory airway disease. Spleen tyrosine kinase (SYK) is a mediator, which acts as an important regulator of intracellular signal transduction in the inflammatory response. SYK was originally identified in hematopoietic cells, and its expression in ...

journal_title：American journal of rhinology & allergy

authors： Na HG,Bae CH,Choi YS,Song SY,Kim YD

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:Criterion standard treatment of allergic fungal sinusitis (AFS) is primary surgery followed by adjuvant therapy. Even after good surgery, recurrence rates vary from 10 to 79%. Antifungals, e.g., itraconazole, and steroids have shown varying success rates in delaying recurrences given after surgery. Itracon...

journal_title：American journal of rhinology & allergy

authors： Patro SK,Verma RK,Panda NK,Chakrabarti A,Singh P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Concerns over radiation exposure with paranasal sinus computed tomography (CT) have recently evolved. Magnetic resonance imaging (MRI) may be more advantageous in this regard, but the diagnostic assessment of MRI in chronic rhinosinusitis (CRS) has not been reported. The purpose of this study was to determin...

journal_title：American journal of rhinology & allergy

authors： Lin HW,Bhattacharyya N

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is recognized as a common disease that imposes a big burden on the health system worldwide. There is ongoing evidence of the anti-inflammatory effect of long-term macrolide in the management of patients with CRS. OBJECTIVE:The aim of this randomized clinical trial was to evaluat...

journal_title：American journal of rhinology & allergy

authors： Amali A,Saedi B,Rahavi-Ezabadi S,Ghazavi H,Hassanpoor N

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The clinical importance of serum squamous cell carcinoma antigen (SCCA) and SCCA subclasses has not been established for treating inverted papilloma (IP). The aim of this study was to clarify the clinical importance of serum SCCA and its subclasses in IP, compared with maxillary squamous cell carcinoma and ...

journal_title：American journal of rhinology & allergy

authors： Suzuki M,Deng Z,Hasegawa M,Uehara T,Kiyuna A,Maeda H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The greater palatine canal (GPC) local injection is used to limit posterior bleeding during sinus surgery in adults. Given the potential for causing iatrogenic damage to the intraorbital contents, this procedure is not commonly used in the pediatric population. No studies have described the anatomic developm...

journal_title：American journal of rhinology & allergy

authors： McKinney KA,Stadler ME,Wong YT,Shah RN,Rose AS,Zdanski CJ,Ebert CS Jr,Wheless SA,Senior BA,Drake AF,Zanation AM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis is commonly treated with antihistamines. Monitoring improvement of airway inflammation noninvasively using nasal nitric oxide (nNO) would be clinically useful. To determine the anti-inflammatory effect of oral levocetirizine dihydrochloride (LC), we measured nNO and nasal eosinophils (nEos...

journal_title：American journal of rhinology & allergy

authors： Bautista AP,Eisenlohr CP,Lanz MJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:B-cell responses may play a role in the pathogenesis of nasal polyposis via local IgA and IgE production and activation of eosinophils and mast cells. B-cell attracting chemokines may therefore have relevance in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNPs) Methods: Polyp and inferio...

journal_title：American journal of rhinology & allergy

authors： Patadia M,Dixon J,Conley D,Chandra R,Peters A,Suh LA,Kato A,Carter R,Harris K,Grammer L,Kern R,Schleimer R

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The ciliary epithelial cells in the paranasal sinuses produce nasal nitric oxide (NO) continuously and plays a variety of roles in the paranasal sinuses. The purpose of this study was to assess whether we can use the levels of nasal NO (nNO) and exhaled NO (eNO) as a tool for evaluation in chronic rhinosinus...

journal_title：American journal of rhinology & allergy

authors： Jeong JH,Yoo HS,Lee SH,Kim KR,Yoon HJ,Kim SH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUNDS:Diagnosis of allergic fungal rhinosinusitis (AFRS) is complicated because of the presence of fungi on mucosal surfaces of sinonasal passages. The objectives of this study were to define, using immunohistochemistry, lymphocyte populations associated with noninvasive fungal-related chronic rhinosinusitis (CRS...

journal_title：American journal of rhinology & allergy

authors： Ragab A,Samaka RM

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Visual Analog Scale (VAS) as determined by the patient is recommended by the European Position Paper on Rhinosinusitis and Nasal Polyps 2012 in evaluation of the total severity of the chronic rhinosinusitis (CRS) patients' symptoms. OBJECTIVE:To evaluate the correlation between evaluations performed by otor...

journal_title：American journal of rhinology & allergy

authors： Zhao L,Yu KN,Tan JL,Zhang HL,Jin P,Zi XX,Tu YY,Li T,Zhou XM,Shi L,Wang Y

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to describe and correlate radiographically the anterior ethmoidal artery (AEA) to useful endoscopic surgical landmarks, such as the nasal beak (NB), nasal crest (NC), and axilla of the middle turbinate, because these are commonly encountered during endoscopic sinus surgery and skull...

journal_title：American journal of rhinology & allergy

authors： Pernas FG,Coughlin AM,Hughes SE,Riascos R,Maeso PA

更新日期：2011-01-01 00:00:00