Crystalline corneal deposits in monoclonal gammopathy: in-vivo confocal microscopy.

Abstract:

PURPOSE:To describe the in-vivo confocal microscopy corneal findings in a patient with bilateral corneal deposits caused by an underlying monoclonal gammopathy. METHODS:A 68-year-old man came to our center for an ophthalmologic examination. Besides visual acuity, the examination included slit-lamp biomicroscopy, intraocular pressure, and fundoscopy. Confocal microscopy was performed using Confoscan 4 (Nidek Technologies Padova, Italy) with a 40× lens because of the presence of bilateral crystalline corneal deposits. Serological tests were also performed. RESULTS:Every layer of the cornea is interested by deposits with high reflectivity,especially the epithelium and anterior stroma. The emathological tests evidenced a monoclonal gammopathy of undetermined significance with high levels of Immunoglobulin M. CONCLUSION:Crystalline corneal deposits in monoclonal gammopathycan be usefully evaluated by confocal microscopy. These manifestations may be evaluated long before systemic signs of the pathology appear, so the early diagnosis is mandatory.

journal_name

Semin Ophthalmol

authors

Paladini I,Pieretti G,Giuntoli M,Abbruzzese G,Menchini U,Mencucci R

doi

10.3109/08820538.2012.730102

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

37-40

issue

1

eissn

0882-0538

issn

1744-5205

journal_volume

28

pub_type

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