Abstract:
PURPOSE:To describe the in-vivo confocal microscopy corneal findings in a patient with bilateral corneal deposits caused by an underlying monoclonal gammopathy. METHODS:A 68-year-old man came to our center for an ophthalmologic examination. Besides visual acuity, the examination included slit-lamp biomicroscopy, intraocular pressure, and fundoscopy. Confocal microscopy was performed using Confoscan 4 (Nidek Technologies Padova, Italy) with a 40× lens because of the presence of bilateral crystalline corneal deposits. Serological tests were also performed. RESULTS:Every layer of the cornea is interested by deposits with high reflectivity,especially the epithelium and anterior stroma. The emathological tests evidenced a monoclonal gammopathy of undetermined significance with high levels of Immunoglobulin M. CONCLUSION:Crystalline corneal deposits in monoclonal gammopathycan be usefully evaluated by confocal microscopy. These manifestations may be evaluated long before systemic signs of the pathology appear, so the early diagnosis is mandatory.
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Paladini I,Pieretti G,Giuntoli M,Abbruzzese G,Menchini U,Mencucci Rdoi
10.3109/08820538.2012.730102subject
Has Abstractpub_date
2013-01-01 00:00:00pages
37-40issue
1eissn
0882-0538issn
1744-5205journal_volume
28pub_type
杂志文章abstract::Purposes: To evaluate the accuracy of Ophtha Top and consistency between Ophtha Top and IOLMaster 500 in intraocular lens refractive power calculation among cataract patients with normal and long axial lengths. Methods: This study included cataract patients scheduled for phacoemulsification and IOL implantation surger...
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journal_title:Seminars in ophthalmology
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abstract:PURPOSE:To investigate thickness of the retinal nerve fiber layer (RNFL) and choroid thickness in patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliation glaucoma (PXG) compared to healthy volunteers. METHODS:This cross-sectional, prospective study included 43 patients with PXG, 45 patients with PEX syndr...
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
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abstract::Purpose: To evaluate detailed corneal parameters of inflammatory bowel disease (IBD) patients, including Crohn's disease (CD) and ulcerative colitis (UC) patients, and to assess associations between anterior segment values and other clinical variables.Methods: This prospective cross-sectional case-control study at a t...
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journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
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更新日期:1995-09-01 00:00:00
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更新日期:2001-06-01 00:00:00
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journal_title:Seminars in ophthalmology
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journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539909056057
更新日期:1999-03-01 00:00:00
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