Abstract:
:Laser photocoagulation of the entire area of the neovascular lesion is the only proven treatment for subfoveal choroidal neovascularization secondary to age-related macular degeneration with a poor natural history. However, there are some limiting factors such as patient eligibility, a significant decline in visual acuity after treatment, and a very low possibility of a final vision of 20/100 or better. Although no large benefit of other treatment modalities, such as indocyanine green videoangiography-guided laser photocoagulation, surgical removal of neovascular membranes, and radiation therapy, has yet been proven, carefully selected patients may be suitable candidates for such treatments. This article reviews the status of treatment modalities for subfoveal choroidal neovascularization secondary to age-related macular degeneration, including laser photocoagulation of the entire area of the neovascular lesion, and discusses factors prognostic of visual outcome in these treatment options.
journal_name
Semin Ophthalmoljournal_title
Seminars in ophthalmologyauthors
Shiraga F,Takasu I,Shiragami Cdoi
10.3109/08820539809066080subject
Has Abstractpub_date
1998-03-01 00:00:00pages
31-9issue
1eissn
0882-0538issn
1744-5205journal_volume
13pub_type
杂志文章,评审abstract:INTRODUCTION:Vernal keratoconjunctivitis (VKC) is a bilateral multi-factorial disease. The pathogenesis of this disease is not obviously determined, but the role of various inflammatory cytokines has been specified. This study has provided a comparison between the level of interleukin-17 (IL17) in the serum and tears o...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2016.1170162
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To describe utilization trends of an ophthalmology-specific emergency department (ED). METHODS:Prospective cohort study of new patients presenting in the ophthalmology ED for at least a 30-day period in the spring of each year for five consecutive years (2010-14) at a university referral center. A data form,...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2016.1188129
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To characterize the prevalence of refractive error and amblyopia among three- to six-year-old children during the period from 2002 to 2011. METHODS:About 31,400 children annually (from 16,592 to 40,816) during the period from 2002 to 2011 were enrolled. The preschool vision screening was performed by the Korea...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2014.912335
更新日期:2015-01-01 00:00:00
abstract::Primary intraocular lymphoma (PIOL) is a type of primary central nervous system lymphoma (PCNSL). It is the most common neoplastic masquerade syndrome involving the eye. Its protean ocular manifestations, plus in many cases the initial positive response to corticosteroid therapy for presumed uveitis, delay accurate di...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530500350498
更新日期:2006-07-01 00:00:00
abstract::Macular hole formation is a rare complication of cataract extraction. Although the exact etiology is unclear, macular holes can be classified into pre-existing holes that may not have been visible prior to cataract surgery, early stage macular holes that progressed to a more advanced stage, symptomatic holes following...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1076/soph.17.3.196.14775
更新日期:2002-09-01 00:00:00
abstract::The onset of post-operative corneal melting and necrotizing scleritis in patients with rheumatoid arthritis and collagen vascular disease who undergo cataract surgery can have devastating ocular and systemic consequences. Even though ocular surface factors such as sicca and surgical trauma are among the important vari...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1076/soph.17.3.124.14786
更新日期:2002-09-01 00:00:00
abstract::The purpose was to investigate the effect of decentered ablation in myopic corneal refractive surgery by simulation. Wavefront aberrations in a small pupil area (radius: 2 mm) for photopic vision and in a large pupil area (radius: 3 mm) for mesopic vision with simulated refractive surgery were analyzed using Zernike p...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1076/soph.18.1.41.14071
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To demonstrate the ability of ultra wide-field fundus imaging to document the response to treatment of a choroidal metastatic lesion from primary breast carcinoma. DESIGN:Observational case report. METHODS:A 45 year old female with a history of metastatic breast cancer and progressive vision loss in the right...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530802520194
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To describe the use of photoscreening for preschool vision screening in several diverse locations throughout the world. METHODS:The MTI photo screener was used to screen pre-verbal children; photographs were interpreted using standard criteria. RESULTS:The Tennessee vision screening program remains successful...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530802506078
更新日期:2008-09-01 00:00:00
abstract::Although the cause of IIH remains obscure, it has become clear that loss of visual function is common and patients may progress to blindness. Diagnosis should adhere to the modified Dandy criteria. Recent case-control studies cast doubt on the validity of many frequently cited conditions associated with IIH. Valid ass...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539509060979
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:To assess the effect of posterior capsular opacification (PCO) and Neodymium-doped:Yttrium Aluminium Garnet (Nd:YAG) laser capsulotomy on tilt and decentration of intraocular lens (IOL) at vertical and horizontal meridians. METHODS:The study included 64 eyes of 64 patients. IOL decentration and tilt were measu...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2018.1443146
更新日期:2018-01-01 00:00:00
abstract::Subfoveal choroidal neovascularization presents one of the most difficult challenges to vision. No treatment option has yet solved the problem of subretinal hemorrhage and fibrovascular scarring causing permanent photoreceptor degeneration and loss. Limited macular translocation provides a surgical approach to this ch...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820530009039997
更新日期:2000-06-01 00:00:00
abstract::The lacrimal drainage system consists of the lacrimal puncta, inferior and superior canaliculi, common canaliculus, lacrimal sac, and nasolacrimal duct. It is classically divided into upper and lower portions. Obstruction of the drainage system can be congenital or acquired, and may result in persistent epiphora and m...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2010.488577
更新日期:2010-05-01 00:00:00
abstract::Current ultra-wide field (UWF) retinal imaging systems utilize scanning laser ophthalmoscope technology combined with an ellipsoidal mirror to capture up to 200 degrees of the retina in a single image. When compared with mydriatic ETDRS-protocol, 7 standard field photographs and clinical examination, nonmydriatic UWF ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2012.708812
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between lens density using the Scheimpflug system and phacodynamics in nuclear cataracts as related to patient age. METHODS:In 262 eyes with nuclear cataracts, the objective lens density was determined by Pentacam Nucleus Staging (PNS) software while subjective grading was achieved...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2015.1120756
更新日期:2017-01-01 00:00:00
abstract::Glaucoma is one of the leading causes of visual impairment worldwide. Classically, clinicians have evaluated patients through a full ophthalmological examination including gonioscopy, measurement of intraocular pressure (IOP), and assessment of the optic nerve. New imaging modalities have further enhanced our ability ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2015.1114858
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To compare the effect of 10% phenylephrine (PE) instillation and manual elevation (ME) on the upper eyelid position of the tested eye and the contralateral eye in patients with involutional blepharoptosis (IB). METHODS:IB patients were submitted to two tests followed by observation of the effect on the contr...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2015.1045152
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To describe the in-vivo confocal microscopy corneal findings in a patient with bilateral corneal deposits caused by an underlying monoclonal gammopathy. METHODS:A 68-year-old man came to our center for an ophthalmologic examination. Besides visual acuity, the examination included slit-lamp biomicroscopy, intra...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2012.730102
更新日期:2013-01-01 00:00:00
abstract::Diabetic retinopathy is one of the most serious complications of chronic diabetes mellitus and is the leading cause of blindness in working-age populations. Large, randomized studies have demonstrated the benefits of systemic and ocular therapy in the prevention and treatment of diabetic retinopathy. The process of an...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.859280
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the quality of life in patients with age-related macular degeneration (AMD) and compare it with that of healthy controls. Additionally, our study aims to investigate the possible risk factors for poor quality of life in AMD patients. METHODS:Participants in the study w...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2016.1181192
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The primary objective of this article is to present a summary of different types of image processing methods employed for the detection of glaucoma, a serious eye disease. INTRODUCTION:Glaucoma affects the optic nerve in which retinal ganglion cells become dead, and this leads to loss of vision. The principa...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820538.2016.1229801
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:Endothelial keratoplasty (EKP) has become increasingly popular in the treatment of corneal disease. However, the global shortage of human donor corneas limits clinical corneal transplantation. Genetically engineered (GE) pigs may provide an alternative source of corneas for EKP. The aim of this study was to eva...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2013.787104
更新日期:2014-05-01 00:00:00
abstract::In the herpetic stromal keratitis (HSK), HSV DNA fragments and HSV-IgG immune complexes (HSV-IC) are present in most of the corneas long after infective virus has disappeared. These viral components are highly immunogenic and potentiate production of proinflammatory cytokines and chemokines via Toll-like receptors (TL...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.1080/08820530802111408
更新日期:2008-07-01 00:00:00
abstract::The optical coherence tomograph is a new, noninvasive technical device that can obtain cross-sectional, high-resolution images-optical coherence tomographs (OCT)-of the retina. This instrument permits an accurate evaluation of various macular and chorioretinal pathologies and the early detection of glaucomatous damage...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539809056053
更新日期:1998-12-01 00:00:00
abstract::Several new aqueous inflow inhibitors have been introduced over the past few years. These new agents include two alpha agonists, two topical carbonic anhydrase inhibitors, and a novel combination agent. All of these agent compare favorably with timolol in terms of aqueous suppression, though each has its own relative ...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820539909061469
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Glaucoma is one of the leading causes of blindness worldwide. Treatment is still largely targeted at lowering intraocular pressure. Intraocular pressures can be lowered through a variety of topical medications, lasers and incisional surgeries. There are currently several classes of topical medications availa...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820538.2020.1818796
更新日期:2020-08-17 00:00:00
abstract::Normal tension glaucoma (NTG) is a common form of open-angle glaucoma that can lead to significant visual morbidity. There has been considerable debate as to whether NTG fits within the spectrum of primary open-angle glaucoma (POAG). The relative roles of intraocular pressure and pressure-independent factors in this d...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章,评审
doi:10.3109/08820538.2013.771202
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:We would like to describe a case report of posterior ischemic optic neuropathy (PION) misdiagnosed as arteritic PION with presumed GCA which leads to missing the correct diagnosis with fatal outcome. METHODS:The clinical course of a single patient will be described including presentation, testing,diagnosis a...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820530903392902
更新日期:2009-11-01 00:00:00
abstract::A 61-year-old female presented with a moderate decrease in vision in the left eye. The patient denied any other ocular or systemic symptoms related to giant cell arteritis. Visual acuity was 20/50 in the left eye with a 2+ relative afferent pupillary defect and markedly abnormal color vision. Dilated fundus examinatio...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.1080/08820530490882715
更新日期:2004-09-01 00:00:00
abstract::Retrospective analysis of epidemiological and clinical characteristics of patients diagnosed with benign essential blepharospasm and hemifacial spasm who reported to the oculoplasty clinic of a tertiary eye care center in north India between January 2010 and April 2015 was carried out. Dry eye, as well as all the loca...
journal_title:Seminars in ophthalmology
pub_type: 杂志文章
doi:10.3109/08820538.2015.1096401
更新日期:2017-01-01 00:00:00