Abstract：
BACKGROUND:Prevention programmes should only be recommended if they achieve what they promise to achieve. Therefore, we checked the variation and validity of recommendations for screening for colorectal cancer of nine organisations. METHODS:We analysed the information concerning recommended screening age, guaiac faecal occult blood test (gFOBT), faecal immunological test (FIT), faecal DNA test, sigmoidoscopy, colonoscopy, double-contrast examination/double-contrast barium enema, and virtual colonoscopy/CT colonography in the following three steps: 1) we gathered the references quoted by the nine organisations; 2) references were categorised according to mortality, incidence and sensitivity/specificity; 3) the validity of references that reported reduced mortality attributed to screening were evaluated. RESULTS:Evidence of occult faecal blood was the only screening method recommended by all nine organisations. Colonoscopy was recommended by seven organisations. Fifteen of the 33 references used endpoints other than mortality to justify screening. One publication was a meta-analysis. Eleven of 17 publications evaluated the gFOBT, three evaluated sigmoidoscopy, one FIT, one coloscopy, and one general diagnosis of the intestine. On average, two of nine validity criteria were completely fulfilled, five only partially, and two were not fulfilled. In two publications, none of the validity criteria were completely met. CONCLUSION:Analysis of screening for colorectal cancer revealed that nine organisations had different goals and different recommendations. Scrupulous and thorough evaluation of the scientific studies in relation to mortality, upon which these recommendations are based, revealed numerous shortcomings and therefore could not sufficiently substantiate the international recommendations for screening for colorectal cancer. It would be useful to establish a consensus about which data have to be collected to provide a reliable basis for health-care decisions.
journal_name
Zentralbl Chirjournal_title
Zentralblatt fur Chirurgieauthors
Porzsolt F,Ittner D,Henne-Bruns Ddoi
10.1055/s-0032-1328074subject
Has Abstractpub_date
2015-08-01 00:00:00pages
390-6issue
4eissn
0044-409Xissn
1438-9592journal_volume
140pub_type
杂志文章,评审abstract：:134 patients with necrotizing pancreatitis were operated. Preoperative organ insufficiency (pulmonary or renal), the presence of shock or sepsis and the intraoperative morbidity factors: parenchymal necroses greater than 30%, extrapancreatic necroses, ascites and in particular bacterial contamination were directly cor...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Therapeutic bronchoscopy is widely used in the treatment of airway stenosis, fistula, and pulmonary bleeding. Recanalisation of tracheobronchial stenoses can be treated by Nd: YAG-laser or stent implantation. While the use of laser irradiation is limited to intraluminal obstruction, stenting is also effective in steno...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：:Immediate operative reconstruction of ligament injuries of the knee joint is recommended for the performance age. The optimal operation time is within 24 hours after the accident, it should be done within 72 hours. The important advantage of this early operation in comparison to a non-operative treatment is the possib...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Stabilisation of pelvic ring fractures by means of external fixation has been found to provide certain advantages over internal fixation. Good results can be achieved, provided that optimum forms and techniques of assembly are used. The authors' indications are reported together with their assembly techniques and form...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:By checking the list of local anaesthetics produced in the GDR containing vasoconstrictor drugs it could be proved that there exist disproportions concerning maximum concentrations and maximum doses of the local anaesthetic on the one hand and epinephrine as well as norepinnephrine concentration on the other. This dan...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:Between 1964 to 1974 2940 patients underwent chest operations. 15 cases with abdominal complications among them are analyzed. 10 patients had bleeding gastric or duodenal ulcers with a high mortality rate. Postoperative gastric distention was one of the most important causes. A gastric tube should be introduced whenev...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Dogs which had received cyclosporine A for immunosuppression were investigated to elucidate functionality and morphological alterations in pancreas allografts, with enteral, vesical, peritoneal or occluded exocrine drainage. None of the animals with enteral drainage survived the first four postoperative weeks, with le...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:The authors report on their experience concerning myocardial protection during open heart surgery making use of hypothermic cardioplegia. From September 1977 to April 1980 they operated on 637 patients applying this method. 155 cases were evaluated. Hypothermic cardioplegia extends the tolerance of the myocardium to i...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:From 1948 to 1977 359 patients suffering from oesophageal reflux disorders or the hiatus-hernia-complex underwent surgery at the I. Surgical clinic of the Medical Faculty Palacky-Univ. in Olomouc. In the group of 50 patients with simple paraaesophageal hernias the operative mortality came up to 4.0%. The mortality rat...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：BACKGROUND:Application of a LapSim-training model in the Students' Skills Lab as well as the objective evaluation of stress in a virtual operating room scenario offer new perspectives in laparoscopic simulation. METHODS:In a Students' Skills Lab , assessment of learning curves of laparoscopic basic skills and complex ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2008-1004744
更新日期：2008-06-01 00:00:00
abstract：:We recommend explorative laparotomy with splenectomy in the field of Hodgkin's lymphoma even in childhood. Operation is an early therapeutic and diagnostic method enabling further treatment to be made in relation to the stages of the disease. A chance of better survival seems to exist in children with Hodgkin's diseas...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND:To be able to evaluate properly a vascular problem, basic concepts of vascular physiology need to be considered, as they have been taught in physiology for a long time. This article deals with selected definitions and laws of passive vascular mechanics, subdivided into parameters of vascular filling and para...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0032-1327967
更新日期：2014-10-01 00:00:00
abstract：:In computed tomography, the mediastinum is split into ventral prevascular, middle visceral and dorsal paravertebral compartments. Each compartment contains specific tumours which will be presented and discussed briefly. The focus is on image-based analysis of morphological signs to differentiate between entities using...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/a-1171-2766
更新日期：2020-07-06 00:00:00
abstract：:In our study, we retrospectively evaluated 203 patients with medial or lateral femoral neck fractures who received 210 bipolar prosthesis (7 bilateral implantations) at our institution. 204 patients underwent cemented bipolar hemiarthroplasty. These included 149 females and 54 males with a median age of 82 (46-97) yea...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-0028-1098711
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Since 1983 gastric banding has become a proven operative method, which reduces effectively excess weight in morbid obesity. Gastric banding has been popularized as a minimally invasive, completely reversible surgical treatment for morbid obesity. We report here our 4 year experiences of gastric banding with ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2000-10650
更新日期：2000-01-01 00:00:00
abstract：:In patients with the first manifestation of hyperthyroidism of Graves' disease, antithyroid drug treatment is the therapy of first choice. Treatment has to be carried out depending on iodine supply of the individual patient with the lowest possible drug dose. Controls of treatment have to be done in short intervals (e...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：:Acute alcohol intoxication causes a lot of diagnostic problems. Every doctor should be well informed about its differential diagnostic aspects. Carelessness concerning diagnosis can be detrimental to the patient and the physician as well. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:In patients with occlusive arterial disease of the lower extremity below knee amputation is successful in 75 to 85%. Below knee amputation enables a better and more rapid prosthetic rehabilitation than above knee amputation, even in very old patients. Indication, amputation technique, and postoperative stump managemen...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1981-01-01 00:00:00
abstract：INTRODUCTION:Intraarterial thrombolysis of acute arterial occlusions in the lower limbs is an established therapeutic procedure. However, its value as a primary treatment is discussed controversially and it is mostly seen as a competing procedure to primary vascular surgical interventions. METHODS:From January 2001 to...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：10.1055/s-2008-1076866
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:The prevalence of morbid obesity and its sequelae is increasing in Germany, Europe and worldwide. Bariatric surgery is thus gaining in importance for the treatment of patients with malignant obesity. Creation of a gastric bypass is one of the most frequently performed procedures for obesity. DISCUSSION:The ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0028-1098812
更新日期：2009-02-01 00:00:00
abstract：:In 1973 the observation was published that in patients who had received non specific blood transfusions before kidney transplantation graft survival was improved. An immunosuppressive effect of blood transfusion was suggested. Indeed, modulation on the cellular and humoral immunologic system has been demonstrated duri...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Lung cancer is one of the leading causes of death in Europe and the USA. A relatively good prognosis is limited to those patients in whom the tumor is detected at an early stage. As clinical symptoms of lung cancer are a late finding in the natural course of the disease, most of the patients are diagnosed at an advanc...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：10.1055/s-0033-1350855
更新日期：2013-10-01 00:00:00
abstract：:A statewide report card system for cholecystectomy as a surgical tracer has been established in Westfalia-Lippe as part of a program of external quality assurance. 74,400 data between 1993 and 1997 were analyzed. Pathologic findings in preoperative diagnostics (sonography, elevated bilirubin) do not lead to therapeuti...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:31 cases of malignant small intestine tumours were treated surgically in a 14 years period. There were no characteristic early signs of disease. The correct preoperative diagnosis was based on radiological examination only. Although radical surgical treatment could be performed in 14 patients only, 29% of the cases re...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Experience of two African and one German Surgical Units on abdominal operations in a two-years period are reported. Appendicitis, gall-stones, cancer of the colon and intestinal diverticulosis are rare in Africa, but frequent in Europe. Possible relations to dietry habits are discussed. ...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:In many patients with varicose veins the combination of surgery and sclerotherapy gives good results and reduces the operating time for each patient considerably. Especially in all patients with recurrent and side branch varicose veins this method seems to be advantageous. During the last ten years we treated 3328 pat...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Normal ranges, which were set up for quality control, serve to define an acceptable qualitative niveau of treatment. To establish such criteria, it is important to consider group-specific characteristics during investigations. Results of clinical trials are the basics to determine the normal range of parameters of qua...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：UNLABELLED:This randomized controlled trial aims to evaluate the influence of preoperative relaxation techniques on postoperative outcomes. From January 1997 to June 1998 208 patients were operated on for primary inguinal hernia or goiter. The patients were randomized into two groups: Group A (n = 103) underwent the su...
journal_title：Zentralblatt fur Chirurgie
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2000-01-01 00:00:00
abstract：:The treatment and outcome of the respiratory failure decisively depend on its pathophysiological background. Besides simple blood gas analysis the investigation of the respiratory mechanics, interstitial lung water and the monitoring of the pulmonary pressure are necessary for an exact diagnosis. As a scoring method o...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Duodenogastric reflux has often been discussed as a causative factor in the pathogenesis of gastric carcinoma. The author's clinical examinations of 135 patients with primary cancer of the stomach revealed slight increase in duodenogastric reflux. Yet, apart from these findings, no correlations were found to exist bet...
journal_title：Zentralblatt fur Chirurgie
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
