Prognosis after "high urgent" kidney transplantation might be determined by control of preexisting septic condition.


INTRODUCTION:Dialysis is the standard bridging method for patients with end-stage renal disease. In rare cases, dialysis is impossible and immediate kidney transplantation (KT) is the only option for survival. Most allocation organizations offer an immediate allocation procedure (high urgency [HU]), which focuses on immediate allocation at the cost of immunologic matching. The impossibility of dialysis is mainly caused by multiple systemic thromboses and blood stream infections. This situation creates an ethical dilemma: Accepting the HU-KT allocation potentially saves the patient's life albeit with negatively effects on the expected patient and organ survivals. In times of organ shortage, more information is needed regarding this difficult decision; the published literature is limited to 4 papers. METHODS:We performed a retrospective analysis of patients who were transplanted by HU allocation in our center between January 1989 and October 2010. RESULTS:Of 1040 KT, 10 (0.96%) were performed in HU condition. Mean follow-up time was 37 months. The main reason for HU-KT was exhaustion of vascular access in combination with a bloodstream infection. All recipients showed severe preoperative comorbidities. Patient survival was 90% at 1, 80% at 3, and 60% at 5 years. There was 1 graft loss owing to chronic rejection. CONCLUSION:When kidney transplantation is performed as an HU procedure, it is associated with a greater morbidity and mortality compared with elective cases. Bloodstream infections that existed before transplantation contributed considerably to mortality.


Transplant Proc


Kleinert R,Wahba R,Heiermann N,Kisner T,Hos N,Stippel DL




Has Abstract


2013-01-01 00:00:00














  • Transitional Study of Patient-Controlled Analgesia Morphine With Ketorolac to Patient-Controlled Analgesia Morphine With Parecoxib Among Donors in Adult Living Donor Liver Transplantation: A Single-Center Experience.

    abstract:BACKGROUND:In this study, as our center transitions from using patient-controlled analgesia (PCA) morphine with intravenous (IV) ketorolac to PCA morphine with IV parecoxib, the two regimens are compared in terms of quality of pain control. METHODS:Post-operative pain management sheets were collected retrospectively a...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lim KI,Liu CK,Chen CL,Wang CH,Huang CJ,Cheng KW,Wu SC,Shih TH,Yang SC,Lee YE,Jawan B,Juang SE

    更新日期:2016-05-01 00:00:00

  • Oxygenated machine perfusion preservation of predamaged kidneys with HTK and Belzer machine perfusion solution: an experimental study in pigs.

    abstract::The objective of the present study was to evaluate the recently proposed aerobic machine preservation with the noncolloidal HTK solution by comparison with the colloidal Belzer machine perfusion solution (MPS) after procurement of marginal kidneys from non-heart-beating donors. Kidneys were harvested 40 minutes after ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Manekeller S,Leuvenink H,Sitzia M,Minor T

    更新日期:2005-10-01 00:00:00

  • Impact of HLA-DPB1 Matching on Outcome of Unrelated Transplant for Hematologic Malignant Diseases: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:Human leukocyte antigen match is the most important donor factor affecting transplant outcome. The HLA-DPB1 mismatch on the clinical outcome of hematopoietic stem cell transplant (HSCT) is less clear. This study is the first meta-analysis to investigate the impact of HLA-DPB1 loci mismatch on clinical outcome...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,meta分析


    authors: Wang Y,Xu S,Fang P

    更新日期:2019-01-01 00:00:00

  • Restricting cadaveric kidney transplantation based on age: the impact on efficiency and equity.

    abstract:BACKGROUND:Caring for patients with end-stage renal disease (ESRD) is resource intense, and health care costs for this small segment of the population continue to rise. When compared to long-term dialysis as a therapy for ESRD, kidney transplantation increases survival, improves quality of life, and is cost saving. ME...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Quinn RR,Manns BJ,McLaughlin KM

    更新日期:2007-06-01 00:00:00

  • Comparison of Incidence and Risk of Depression in Recipients of Renal Transplantation and Patients Undergoing Hemodialysis in China.

    abstract:AIM:To investigate depressive symptoms in recipients of renal transplantation (RTx) compared with patients undergoing hemodialysis (HD) in China. METHODS:Forty-two Chinese recipients of transplant and 42 Chinese patients on hemodialysis were randomly selected from 2011 to 2012. These 2 groups were assessed with the va...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Wang Y,Bu T,Yan P,Yao H

    更新日期:2018-12-01 00:00:00

  • C-terminal peptide of anaphylatoxin C3a enhances hepatic function after steatotic liver transplantation: a study in a rat model.

    abstract:BACKGROUND:C3a, a complement component stimulates hepatocyte proliferation. In this study, we investigated whether a functional peptide from its C terminal, YAAALGLAR (C3aP), enhanced liver function after steatotic liver transplantation in a rat model. METHODS:Livers of Sprague-Dawley (SD) rats fed a high-fat diet for...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Xu XH,Peng HS,Sun MQ,Hu M,Zhang R,Wang WH,He XY,Xiao XR

    更新日期:2010-04-01 00:00:00

  • Experience with cyclosporine: from revolution to evolution of immunosuppressive protocols in thoracic organ transplantation.

    abstract::The introduction of cyclosporine into clinical practice of thoracic organ transplantation had a dramatic and positive effect on both short- and long-term survival. Today, the majority of patients are still treated with this drug, and different immunosuppressive combination therapies have further resulted in improved l...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Haverich A,Gorler H

    更新日期:2004-03-01 00:00:00

  • Diagnostic value of antibodies against Pseudomonas aeruginosa in bronchoalveolar lavage fluid after lung transplantation.

    abstract:BACKGROUND:Pseudomonal airway colonization is a risk factor for chronic allograft dysfunction after lung transplantation (LTx). Pseudomonas aeruginosa exoproteases are involved in initiating colonization, and immune complexes directed against these proteases may activate innate immune responses. OBJECTIVE:To investiga...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Vos R,Vanaudenaerde BM,Verleden SE,De Vleeschauwer SI,Willems-Widyastuti A,Van Raemdonck DE,Dupont LJ,Verleden GM

    更新日期:2010-12-01 00:00:00

  • No harmful effect of mycophenolate mofetil on liver regeneration: an experimental study.

    abstract:AIM:The aim of this experimental study was to examine the effects of mycophenolate mofetil (MMF) on liver regeneration in a partial hepatectomy model. METHODS:Rats were divided into 3 groups immediately following partial liver resection: saline, controls intraperitoneally (MMF; Group 1); MMF (15 mg/kg/d; Group II), an...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Demiray M,Kucuk HF,Yildirim M,Barisik NO

    更新日期:2012-07-01 00:00:00

  • Identifying Predictors of Outcomes in Combined Heart and Liver Transplantation.

    abstract:BACKGROUND:Combined heart and liver transplant (CHLT) is a complex procedure that is being increasingly performed. Because of the relative rarity of this procedure, graft and patient outcomes are still being assessed and risk factors for graft and patient survival are unknown. MATERIALS AND METHODS:This is a retrospec...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lee S,Matsuoka L,Cao S,Groshen S,Alexopoulos SP

    更新日期:2019-01-01 00:00:00

  • Fasting long-acting natriuretic peptide correlates inversely with metabolic syndrome in kidney transplant patients.

    abstract::The metabolic syndrome (MetS) is a risk factor for posttransplant diabetes mellitus, chronic graft dysfunction, graft loss, occurrence of atherosclerotic events, and patient death among kidney transplantation patients. Long-acting natriuretic peptide (LANP) is among the peptide hormones in atrial natriuretic peptide p...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Hsu BG,Shih MH,Yang YC,Ho GJ,Lee MC

    更新日期:2012-04-01 00:00:00

  • Prospective study of infection and nephropathy due to BK and JC polyomavirus in 76 kidney transplant recipients.

    abstract:INTRODUCTION:Nephropathy due to polyomavirus is usually diagnosed by renal biopsy after worsening of renal function. This is normally at an advanced stage of the disease. AIM:To study the early detection of the presence of BK and JC polyomavirus in urine by monthly real-time quantitative polymerase chain reaction (PCR...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: López V,Gutiérrez C,Burgos D,González Molina M,Cabello M,Sola E,Garcia I,Siles J,Florez P

    更新日期:2008-11-01 00:00:00

  • Optimized technique in needle biopsy protocol shown to be of greater sensitivity and accuracy compared to wedge biopsy.

    abstract:BACKGROUND:Kidney biopsy is an important tool in determining allograft suitability for transplantation. Most deceased-donor renal biopsies performed today in the United States are wedge biopsies (WBs), with core needle biopsies being performed only by a minority of organ procurement organizations (OPOs). The lack of a ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yushkov Y,Dikman S,Alvarez-Casas J,Giudice A,Hoffman A,Goldstein MJ

    更新日期:2010-09-01 00:00:00

  • Treatment with cinacalcet in 29 kidney transplant patients with persistent hyperparathyroidism.

    abstract:OBJECTIVE:Persistent hyperparathyroidism (HPT) with hypercalcemia and hypophosphatemia is common after renal transplantation, resulting in the need for parathyroidectomy. Cinacalcet may be a therapeutic option for these patients. We sought to analyze the efficacy of treatment with cinacalcet for patients with hypercalc...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: López V,Toledo R,Sola E,Gutiérrez C,Sujan S,Rodríguez MA,Cabello M,Burgos D,González Molina M,Hernández D

    更新日期:2009-07-01 00:00:00

  • Portopulmonary hypertension: imatinib as a novel treatment and the Emory experience with this condition.

    abstract::Portopulmonary hypertension (PoPH) is a common and feared complication of end-stage liver disease, and imposes increased risk of perioperative morbidity in the liver transplant patient. Herein, we present the first successful use of Imatinib in the perioperative management of a patient who was not responding to conven...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Tapper EB,Knowles D,Heffron T,Lawrence EC,Csete M

    更新日期:2009-06-01 00:00:00

  • A Case Report of the Resolution of Multiple Recalcitrant Verrucae in a Renal Transplant Recipient After a Mycophenolate Mofetil Dose Reduction.

    abstract::Renal transplant recipients are at an increased risk of developing verrucae due to chronic immunosuppression, and certain therapies may confer a greater risk. Herein, we describe a 51-year-old woman with a 10-year-old unrelated kidney transplant who developed numerous therapy-resistant verrucae while on mycophenolate ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Ash MM,Jolly PS

    更新日期:2017-01-01 00:00:00

  • Effects of Granulocyte and Monocyte Adsorptive Apheresis in Renal Transplantation Recipients With Concomitant Cytomegalovirus Infection.

    abstract:BACKGROUND:Granulocyte and monocyte adsorptive apheresis (GMAA) is widely used as a treatment for active ulcerative colitis (UC) in Japan. Much attention has been paid to the possibility of GMAA for the treatment and control of cytomegalovirus (CMV) reactivation in patients with refractory UC and concomitant CMV infect...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Naganuma T,Takemoto Y,Iwai T,Kuwabara N,Uchida J,Nakatani T,Kitamura K,Masuda A,Ohmori K,Matsuura M,Nakase H

    更新日期:2016-04-01 00:00:00

  • Critical progressive small-graft injury caused by intrasinusoidal pressure elevation following living donor liver transplantation.

    abstract::In adult-to-adult living liver transplantation, small-for-size graft syndrome sometimes occurs. The relationship between the hemodynamic changes and histologic findings has not been studied in patients with failure of small-for-size grafts. We analyzed the relationship between the postoperative hemodynamic changes and...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Sugimoto H,Kaneko T,Hirota M,Nagasaka T,Kobayashi T,Inoue S,Takeda S,Kiuchi T,Nakao A

    更新日期:2004-11-01 00:00:00

  • Information channels and the dynamics of uptake of living kidney donors: a retrospective study in a reference area.

    abstract:INTRODUCTION:Activity in renal transplantation at our center continues to grow due to the gradual increase in living donor kidney transplantations (LDKT). Our objective was to describe the generation process of living donation in our area of influence including two provinces and 18 chronic kidney disease (CKD) treatmen...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Vidal Blandino M,Gentil Govantes MA,Cabello Chaves V,Pereira Palomo P,Bernal Blanco G,Gonzalez Roncero FM,Fijo Viota J,Medina López R

    更新日期:2011-07-01 00:00:00

  • The potential organ donor pool: international figures.

    abstract::By understanding the size and characteristics of the potential donor pool, the concentration and location of the potential donors and factors influencing low rates of donation, it is possible to identify opportunities to improve the organ donation system. The exact donor gap needs to be established for each hospital/a...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Miranda B,Fernández Lucas M,Matesanz R

    更新日期:1997-02-01 00:00:00

  • A Noninvasive and Donor-independent Method Simultaneously Monitors Rejection and Infection in Patients With Organ Transplant.

    abstract:BACKGROUND:Rejection and infection are 2 major complications affecting the health and survival of patients receiving an allograft organ transplantation. We describe a diagnostic assay that simultaneously monitors for rejection and infection in recipients of kidney transplant by sequencing of cell-free DNA (cfDNA) in pl...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Zhou Y,Yang G,Liu H,Chen Y,Li X,Ge J,Wang X,Niu H,Dong W,Jiang T,Shi H,Peng L,Liu L

    更新日期:2019-01-01 00:00:00

  • FK778 controls acute rejection after rat liver allotransplantation showing positive interaction with FK506.

    abstract::This study including prevention and rescue experiments was performed to examine the efficacy of FK778 and its interactions with FK506. In the prevention experiment, Brown-Norway rats transplanted with a 7 Lewis livers received day-course of FK778 or a combination of FK778 and FK506 treatment. For the rescue experiment...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yamamoto S,Okuda T,Yamasaki K,Tanaka H,Takemura S,Minamiyama Y,Ikeda K,Hirohashi K,Suehiro S

    更新日期:2005-01-01 00:00:00

  • Prognostic Value of Pre-transplantation Serum Alpha-Fetoprotein Levels in Hepatocellular Carcinoma Recurrence.

    abstract::Serum alpha-fetoprotein (AFP) value is still not included in the consensus guidelines to make decisions referring to liver transplantation (LT) for hepatocellular carcinoma (HCC). Many studies demonstrated the influence of high AFP level in poor prognosis after LT for HCC. We studied 301 consecutive recipients transpl...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Montalvá EM,Cantos M,Boscà A,Rubín A,Vinaixa C,Granero P,Maupoey J,López-Andújar R

    更新日期:2016-11-01 00:00:00

  • Liver transplantation for Wilson's disease in pediatric patients: decision making and timing.

    abstract::Transplantation for Wilson's disease occupies 1/3 of the cases for metabolic diseases in Japan. At the end of 2009, 109 transplantations had been performed including three deceased donor cases in the Japanese registry. We herein discuss problems of transplantation for Wilson's disease as well as its indication, timing...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Narumi S,Umehara M,Toyoki Y,Ishido K,Kudo D,Kimura N,Kobayashi T,Sugai M,Hakamada K

    更新日期:2012-03-01 00:00:00

  • Tacrolimus-related neurologic and renal complications in liver transplantation: A single-center experience.

    abstract::Among 71 patients, 19 (26.7%) experienced tacrolimus-related complications including 15 neurologic reactions and four problems with nephrotoxicity. Seven of these patients received grafts from cadaveric donors and 12 from living donors. Nine patients were children. The cohort included 5 female and 14 male subjects of ...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Emiroglu R,Ayvaz I,Moray G,Karakayali H,Haberal M

    更新日期:2006-03-01 00:00:00

  • Renal event outcomes in intestinal transplantation: results from a single-center experience.

    abstract:BACKGROUND:Poor patient outcomes have been closely linked with perioperative renal function after most solid organ transplants, except intestinal transplantation (ITx). This study examined the effect of peri-ITx renal function on outcome. PATIENTS AND METHODS:A retrospective review of all patients undergoing ITx since...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Kaldas F,Farmer D,Gordon SA,McDiarmid SV,Venick R,Colangelo J,Busuttil RW

    更新日期:2007-12-01 00:00:00

  • Recipient Age for Liver Transplantation: Should It Be Limited? A Propensity Score Matching Analysis of a Large European Series.

    abstract:BACKGROUND AND AIMS:The demand for older patients not to be denied access to liver transplantation (LT) has intensified as the European population continues to live longer and maintains better health. AIM:This study aims to ascertain the impact of recipient age on the post-LT survival in 2 well-balanced populations at...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Gómez-Gavara C,Charco R,Tapiolas I,Ridaura N,Campos-Varela I,Dopazo C,Pando E,Caralt M,Hidalgo E,Castells L,Bilbao I

    更新日期:2020-06-01 00:00:00

  • Thromboelastography-guided transfusion decreases intraoperative blood transfusion during orthotopic liver transplantation: randomized clinical trial.

    abstract:OBJECTIVE:To test in a prospective randomized study the hypothesis that use of thromboelastography (TEG) decreases blood transfusion during major surgery. MATERIAL AND METHODS:Twenty-eight patients undergoing orthotopic liver transplantation were recruited over 2 years. Patients were randomized into 2 groups: those mo...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章,随机对照试验


    authors: Wang SC,Shieh JF,Chang KY,Chu YC,Liu CS,Loong CC,Chan KH,Mandell S,Tsou MY

    更新日期:2010-09-01 00:00:00

  • Factors affecting graft survival after living donor liver transplantation.

    abstract::Living donor liver transplantation (LDLT) has been considered as an alternative option to resolve the shortage of cadaveric donor organs, despite the ethical aspects of the donor procedure. The objective of this study was to analyze the risk factors affecting graft survival in LDLT. From June 1996 to December 2002, 14...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Lee DS,Gil WH,Lee HH,Lee KW,Lee SK,Kim SJ,Choi SH,Heo JS,Hyon WS,Kim GS,Paik SW,Koh KC,Joh JW

    更新日期:2004-10-01 00:00:00

  • Monitoring of CD3(+) T-cell count in patients receiving antithymocyte globulin induction after cadaveric renal transplantation.

    abstract:AIM:Although antithymocyte globulin (ATG) has been used for years, its ideal dose and administration period is obscure. Herein, we sought to use the CD3(+) cell count to detect the optimal ATG dosage. MATERIAL AND METHODS:Twenty-one patients who underwent cadaveric donor renal transplantation from January 2009 to Janu...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Ata P,Kara M,Özdemir E,Canbakan M,Gökçe AM,Bayraktar FA,Şahin G,Özel L,Titiz MI

    更新日期:2013-04-01 00:00:00