Urinary monoclonal free light chains in primary Sjögren's syndrome: an aid to the diagnosis of malignant lymphoma.

abstract：:The anti-inflammatory effect of single doses and combinations of aspirin and commonly used nonsteroidal anti-inflammatory drugs was investigated by the polyurethane sponge implantation model of acute inflammation. Dose response curves were performed to delineate a suppressive (high) and nonsuppressive (low) dose of ea...

journal_title：Annals of the rheumatic diseases

authors： Garrett R,Manthey B,Vernon-Roberts B,Brooks PM

更新日期：1983-08-01 00:00:00

abstract：:Premature death has been long recognised as a manifestation of rheumatoid arthritis (RA). Three lines of evidence can explain why patients with RA die prematurely and why the mortality gap between patients with RA and the general population appears to widening. First, patients with RA have a higher risk of several ser...

journal_title：Annals of the rheumatic diseases

authors： Gabriel SE

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:The relationship between radiographic evidence of osteoarthritis and knee pain has been weak. This may be because features that best discriminate knees with pain have not been included in analyses. We tested the correlation between knee pain and radiographic features taking into account both image analysis f...

journal_title：Annals of the rheumatic diseases

authors： Minciullo L,Parkes MJ,Felson DT,Cootes TF

更新日期：2018-11-01 00:00:00

abstract：:Serum C2 activity was measured in 135 individuals drawn from a panel of 418 tissue-typed blood donors. The study group included all donors with HLA antigens A10 and B18. Heterozygote C2 deficiency (C2Dhet) was defined by reference to the range of C2 activity in previously studied obligate heterozygotes. Five donors we...

journal_title：Annals of the rheumatic diseases

authors： Rynes RI,Britten AF,Pickering RJ

更新日期：1982-02-01 00:00:00

abstract：:Three patients are presented who sustained bilateral rupture of the Achilles tendon while on systemic steroid therapy for chest disease; a fourth patient with polymyalgia rheumatica on steroids is also presented. This is further evidence that tendon rupture can be a direct complication of steroid treatment. The Englis...

journal_title：Annals of the rheumatic diseases

authors： Haines JF

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:To determine whether two adults with stress fractures receiving low weekly doses of methotrexate had methotrexate osteopathy. CASE REPORTS:Two adult patients developed features consistent with methotrexate osteopathy while receiving low weekly doses of methotrexate. METHODS:Iliac crest biopsy samples were t...

journal_title：Annals of the rheumatic diseases

authors： Preston SJ,Diamond T,Scott A,Laurent MR

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Oxidative stress in RA synovial tissue can cause DNA damage and suppress the DNA mismatch repair (MMR) system in cultured synoviocytes. This mechanism includes two enzyme complexes, hMutSalpha (hMSH2/hMSH6) and hMutSbeta (hMSH2/hMSH3). OBJECTIVE:To examine the expression and distribution of MMR enzymes in s...

journal_title：Annals of the rheumatic diseases

authors： Simelyte E,Boyle DL,Firestein GS

更新日期：2004-12-01 00:00:00

abstract：:Evidence is presented that a single injection of bacterial antigen in oil into a footpad of rats of 5 strains induced different clinical forms of adjuvant disease in the individual rat strains. Rats were injected with 300 micrograms heat-killed Mycobacterium tuberculosis in 50 microliters paraffin. Inflammatory lesion...

journal_title：Annals of the rheumatic diseases

authors： Muir VY,Dumonde DC

更新日期：1982-10-01 00:00:00

abstract：OBJECTIVE:To define the role of ultrasound (US) for the assessment of patients with rheumatoid arthritis (RA) in clinical remission, including joint and tendon evaluation. METHODS:A multicentre longitudinal study has been promoted by the US Study Group of the Italian Society for Rheumatology. 25 Italian centres partic...

journal_title：Annals of the rheumatic diseases

authors： Filippou G,Sakellariou G,Scirè CA,Carrara G,Rumi F,Bellis E,Adinolfi A,Batticciotto A,Bortoluzzi A,Cagnotto G,Caprioli M,Canzoni M,Cavatorta FP,De Lucia O,Di Sabatino V,Draghessi A,Farina I,Focherini MC,Gabba A,Guti

更新日期：2018-09-01 00:00:00

abstract：AIM:to evaluate the effects of adalimumab, etanercept and infliximab on disease activity, functional ability and quality of life and the medication costs in a naturalistic design. METHODS:All patients from the Dutch Rheumatoid Arthritis Monitoring (DREAM) register starting on tumour necrosis factor (TNF)alpha-blocking...

journal_title：Annals of the rheumatic diseases

authors： Kievit W,Adang EM,Fransen J,Kuper HH,van de Laar MA,Jansen TL,De Gendt CM,De Rooij DJ,Brus HL,Van Oijen PC,Van Riel PC

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:There are no agreed criteria for osteoarthritis (OA) of the knee in population studies. The radiographic scoring system of Kellgren and Lawrence has been the system most used in the past and although other methods have been developed, comparisons have not been performed. Therefore these grading systems were ...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Hart DJ,Byrne J,Harris PA,Dacre JE,Doyle DV

更新日期：1993-11-01 00:00:00

abstract：:The cartilage-pannus junction has been studied in multiple sections from 23 rheumatoid joints. Changes suggesting a metaplastic reaction of the articular cartilage, termed transitional fibroblastic zone, were commonly found in hips and knees, but were rarely present in metatarsophalangeal joints, in which an invasive ...

journal_title：Annals of the rheumatic diseases

authors： Allard SA,Muirden KD,Maini RN

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:Spondyloarthritis is a group of articular disorders sharing a genetic background. Polymorphisms in the IL-1 gene cluster have previously been associated with ankylosing spondylitis (AS), a subset of spondyloarthritis. This study examined the association between several of these polymorphisms and the whole spo...

journal_title：Annals of the rheumatic diseases

authors： Monnet D,Kadi A,Izac B,Lebrun N,Letourneur F,Zinovieva E,Said-Nahal R,Chiocchia G,Breban M

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:The aorta inhibits paravertebral ossification in diffuse idiopathic skeletal hyperostosis. We investigated if syndesmophytes in ankylosing spondylitis (AS) occurred less often at the vertebral rim near the aorta. METHODS:We performed thoracolumbar CT scans in 60 subjects in this cross-sectional study. The m...

journal_title：Annals of the rheumatic diseases

authors： Tan S,Dasgupta A,Flynn JA,Ward MM

更新日期：2019-07-01 00:00:00

abstract：:A case of pachydermoperiostosis characterised by the presence of finger clubbing, periostosis, sweating of hands and feet is described. Modifications of capillaroscopic pattern and of arteriovenous anastomoses are reported. The periungual border and finger tip tissue showed diffuse endothelial hyperplasia, hyalinosis,...

journal_title：Annals of the rheumatic diseases

authors： Matucci-Cerinic M,Cinti S,Morroni M,Lotti T,Nuzzaci G,Lucente E,di Lollo S,Ceruso M,Cagnoni M

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:Advanced imaging studies have demonstrated that urate deposition in periarticular structures, such as tendons, is common in gout. The aim of this study was to investigate the effects of monosodium urate monohydrate (MSU) crystals on tenocyte viability and function. METHODS:The histological appearance of ten...

journal_title：Annals of the rheumatic diseases

authors： Chhana A,Callon KE,Dray M,Pool B,Naot D,Gamble GD,Coleman B,McCarthy G,McQueen FM,Cornish J,Dalbeth N

更新日期：2014-09-01 00:00:00

abstract：:Two British secondary schools (one a specialist music school) were surveyed to assess the prevalence of upper limb pain among specialist music students compared with students in a regular school setting. Female students tended to report pain more often than male students, but for both significantly higher prevalence w...

journal_title：Annals of the rheumatic diseases

authors： Fry HJ,Rowley GL

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVES:To investigate the incidence of cancer in arthritis patients treated with or without TNFα inhibitors (TNF-I). METHODS:Arthritis patients from the DANBIO database were followed-up for cancer in the Danish Cancer Registry during 2000-2008. RESULTS:Hazard ratio for cancer overall was 1.02 (95% confidence inte...

journal_title：Annals of the rheumatic diseases

authors： Dreyer L,Mellemkjær L,Andersen AR,Bennett P,Poulsen UE,Juulsgaard Ellingsen T,Hansen TH,Jensen DV,Linde L,Lindegaard HM,Loft AG,Nordin H,Omerovic E,Rasmussen C,Schlemmer A,Tarp U,Hetland ML

更新日期：2013-01-01 00:00:00

abstract：:Arthro-osteitis at the anterior chest wall was found in 12 (9.4%) out of 128 consecutive patients with pustulosis palmaris et plantaris. This finding indicates that the concomitance of arthro-osteitis with PPP is not incidental but is based on some common aetiological factor. We propose a term ;pustulotic arthro-ostei...

journal_title：Annals of the rheumatic diseases

authors： Sonozaki H,Kawashima M,Hongo O,Yaoita H,Ikeno M,Matsuura M,Okai K,Azuma A

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVE:Hand osteoarthritis is a prevalent disease with limited treatment options. Since joint inflammation is often present, we investigated tumour necrosis factor (TNF) as treatment target in patients with proven joint inflammation in a proof-of-concept study. METHODS:This 1-year, double-blind, randomised, multice...

journal_title：Annals of the rheumatic diseases

authors： Kloppenburg M,Ramonda R,Bobacz K,Kwok WY,Elewaut D,Huizinga TWJ,Kroon FPB,Punzi L,Smolen JS,Vander Cruyssen B,Wolterbeek R,Verbruggen G,Wittoek R

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Treatment with tumour necrosis factor inhibitors (TNF-i) plus methotrexate (MTX), but not MTX monotherapy alone, inhibits joint damage progression even at higher levels of disease activity. Such disassociation of disease activity and structural damage has not been shown for biological agents other than TNF-i...

journal_title：Annals of the rheumatic diseases

authors： Smolen JS,Avila JC,Aletaha D

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Reduced caveolin-1 levels in lung fibroblasts from patients with scleroderma and the lungs of bleomycin-treated mice promote collagen overexpression and lung fibrosis. This study was undertaken to determine whether caveolin-1 is deficient in leucocytes from bleomycin-treated mice and patients with scleroderm...

journal_title：Annals of the rheumatic diseases

authors： Tourkina E,Richard M,Oates J,Hofbauer A,Bonner M,Gööz P,Visconti R,Zhang J,Znoyko S,Hatfield CM,Silver RM,Hoffman S

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:High resolution ultrasound (HRUS) was used to investigate the effects of tumour necrosis factor alpha (TNFalpha) blockade on pannus formation and vascularisation of small finger joints in patients with active rheumatoid arthritis (RA). METHODS:Five patients with active RA were treated with etanercept, a solu...

journal_title：Annals of the rheumatic diseases

authors： Hau M,Kneitz C,Tony HP,Keberle M,Jahns R,Jenett M

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Over 50% of patients with rheumatoid arthritis (RA) harbour a variety of anti-modified protein antibodies (AMPA) against different post-translationally modified (PTM) proteins, including anti-carbamylated protein (anti-CarP) antibodies. At present, it is unknown how AMPA are generated and how autoreactive B ...

journal_title：Annals of the rheumatic diseases

authors： Dekkers JS,Verheul MK,Stoop JN,Liu B,Ioan-Facsinay A,van Veelen PA,de Ru AH,Janssen GMC,Hegen M,Rapecki S,Huizinga TWJ,Trouw LA,Toes REM

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To elaborate a clinical practice decision tree for the choice of the first disease modifying antirheumatic drug (DMARD) for untreated rheumatoid arthritis of less than six months' duration. METHODS:Four steps were employed: (1) review of published reports on DMARD efficacy against rheumatoid arthritis; (2) i...

journal_title：Annals of the rheumatic diseases

authors： Le Loët X,Berthelot JM,Cantagrel A,Combe B,De Bandt M,Fautrel B,Flipo RM,Lioté F,Maillefert JF,Meyer O,Saraux A,Wendling D,Guillemin F

更新日期：2006-01-01 00:00:00

abstract：:Osteotomies on 101 knees in 79 patients were assessed either prospectively or retrospectively. High tibial osteotomy was performed in 54 knees (27 with rheumatoid arthritis (RA) and 27 with osteoarthrosis (OA)) and double (tibiofemoral) osteotomy in 47 knees (25 RA and 22 OA), and were assessed prospectively in 46 and...

journal_title：Annals of the rheumatic diseases

authors： Iveson JM,Longton EB,Wright V

更新日期：1977-08-01 00:00:00

abstract：:A 17-year-old female patient with systemic lupus erythematosus (SLE) developed chronic tophaceous gout, chondrocalcinosis and articular capsule calcification in several joints. Analysis of synovial fluid and tophi revealed the coexistence of monosodium urate, calcium pyrophosphate, hydroxyapatite, and cholesterol crys...

journal_title：Annals of the rheumatic diseases

authors： Rodríguez MA,Paul H,Abadí I,Bravo JR,Armas P

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:We aimed to evaluate the dynamics of treatment response with different composite measures in the TIght COntrol of inflammation in early Psoriatic Arthritis (TICOPA) trial. METHODS:Participants with early disease-modifying antirheumatic drug-naïve psoriatic arthritis (PsA) were randomised 1:1 to either tight...

journal_title：Annals of the rheumatic diseases

authors： Coates LC,Mahmood F,Emery P,Conaghan PG,Helliwell PS

更新日期：2017-10-01 00:00:00

abstract：:The regression of small rheumatoid nodules was noted in four patients after starting sulphasalazine therapy. This coincided with an improvement in synovitis and also falls in erythrocyte sedimentation rate (ESR) and C reactive protein (CRP). The relation between the nodule regression and the sulphasalazine therapy is ...

journal_title：Annals of the rheumatic diseases

authors： Englert HJ,Hughes GR,Walport MJ

更新日期：1987-03-01 00:00:00

abstract：:Three patients presented with septal fasciitis and panniculitis, associated with clinical and laboratory features which precluded straight-forward classification into eosinophilic fasciitis, localised scleroderma, or lupus erythematosus profundus. Treatment with cimetidine caused the remission of cutaneous manifestati...

journal_title：Annals of the rheumatic diseases

authors： Naschitz JE,Yeshurun D,Rosner I,Abrahamson JE,Misselevitch I,Boss JH

更新日期：1990-10-01 00:00:00