Abstract:
:The relationship between blood oxygenation level dependent-functional magnetic resonance imaging (BOLD-fMRI) and magnetoencephalography (MEG) metrics were explored using low-level visual stimuli known to elicit a rich variety of neural responses. Stimuli were either perceptually isoluminant red/green or luminance-modulated black/yellow square-wave gratings with spatial frequencies of 0.5, 3, and 6 cycles per degree. Neural responses were measured with BOLD-fMRI (3-tesla) and whole head MEG. For all stimuli, the BOLD response showed bilateral activation of early visual cortex that was greater in the contralateral hemisphere. There was variation between individuals but weak, or no evidence, of amplitude dependence on either spatial frequency or the presence of luminance contrast. In contrast, beamformer analysis of MEG data showed activation in contralateral early visual cortex and revealed: (i) evoked responses with stimulus-dependent amplitude and latency; (ii) gamma and high-beta oscillations, with spatial frequency dependent peaks at approximately 30 and 50 Hz, but only for luminance-modulated gratings; (iii) The gamma and beta oscillations appeared to show different spatial frequency tuning profiles; (iv) much weaker gamma and beta responses, and at higher oscillation frequencies, for isoluminant compared to luminance-modulated gratings. The results provide further evidence that the relationship between the fMRI-BOLD response and cortical neural activity is complex, with BOLD-fMRI being insensitive to substantial changes in neural activity. All stimuli were clearly visible to participants and so the paucity of gamma oscillations to isoluminant stimuli is inconsistent with theories of their role in conscious visual perception.
journal_name
Front Hum Neuroscijournal_title
Frontiers in human neuroscienceauthors
Swettenham JB,Muthukumaraswamy SD,Singh KDdoi
10.3389/fnhum.2013.00076subject
Has Abstractpub_date
2013-03-11 00:00:00pages
76issn
1662-5161journal_volume
7pub_type
杂志文章abstract::Real-world memories involve the integration of multiple events across time, yet the mechanisms underlying this integration is unknown. Recent rodent studies show that distinct memories encoded within a few hours, but not several days, share a common neural ensemble, and a common fate whereby later fear conditioning ca...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2019.00315
更新日期:2019-09-13 00:00:00
abstract::Accurate estimates of the time-to-contact (TTC) of approaching objects are crucial for survival. We used an ecologically valid driving simulation to compare and contrast the neural substrates of egocentric (head-on approach) and allocentric (lateral approach) TTC tasks in a fully factorial, event-related fMRI design. ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/neuro.09.010.2008
更新日期:2008-09-13 00:00:00
abstract::Besides allowing us to perceive our surroundings, eye movements are also a window into our mind and a rich source of information on who we are, how we feel, and what we do. Here we show that eye movements during an everyday task predict aspects of our personality. We tracked eye movements of 42 participants while they...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2018.00105
更新日期:2018-04-13 00:00:00
abstract::Propylene glycol, also denoted as 1.2 propanediol (C3H8O2), often serves as a solvent for dilution of olfactory stimuli. It is supposed to serve as a neutral substance and has been used in many behavioral and electrophysiological studies to dilute pure olfactory stimuli. However, the effect of propylene glycol on perc...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2019.00099
更新日期:2019-03-20 00:00:00
abstract::Focusing on avoiding failure or negative outcomes (avoidance motivation) can undermine creativity, due to cognitive (e.g., threat appraisals), affective (e.g., anxiety), and volitional processes (e.g., low intrinsic motivation). This can be problematic for people who are avoidance motivated by nature and in situations...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章,评审
doi:10.3389/fnhum.2014.00105
更新日期:2014-02-28 00:00:00
abstract::Research supports an association between extraversion and dopamine (DA) functioning. DA facilitates incentive motivation and the conditioning and incentive encoding of contexts that predict reward. Therefore, we assessed whether extraversion is related to the efficacy of acquiring conditioned contextual facilitation o...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00288
更新日期:2013-06-13 00:00:00
abstract::Anecdotal literature suggests that creative people sometimes use bodily movement to help overcome mental blocks and lack of inspiration. Several studies have shown that physical exercise may sometimes enhance creative thinking, but the evidence is still inconclusive. In this study we investigated whether creativity in...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00824
更新日期:2013-12-02 00:00:00
abstract::Neuroimaging studies of major depressive disorder (MDD) have consistently observed functional and structural changes of the hippocampus (HP) and amygdale (AY). Thus, these brain regions appear to be critical elements of the pathophysiology of MDD. The HP and AY directly interact and show broad and overlapping intrinsi...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00639
更新日期:2013-10-01 00:00:00
abstract::The prevalence of childhood overweight and obesity is increasing in the last decades, also in children with Cerebral Palsy (CP). Even though it has been established that an increase in weight can have important negative effects on gait in healthy adults and children, it has not been investigated what the effect is of ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2016.00657
更新日期:2016-12-23 00:00:00
abstract::In the last decade, an increasing interest has arisen in investigating the relationship between the electrophysiological and hemodynamic measurements of brain activity, such as EEG and (BOLD) fMRI. In particular, changes in BOLD have been shown to be associated with changes in the spectral profile of neural activity, ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2014.00186
更新日期:2014-04-01 00:00:00
abstract::To investigate the neural systems that contribute to the formation of complex, self-relevant emotional memories, dedicated fans of rival college basketball teams watched a competitive game while undergoing functional magnetic resonance imaging (fMRI). During a subsequent recognition memory task, participants were show...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2010.00034
更新日期:2010-05-18 00:00:00
abstract::The relation between primary motor cortex (M1) activity and (muscular) force output has been studied extensively. Results from previous studies indicate that activity of a part of yet unidentified neurons in M1 are positively correlated with increased force levels. One considerable candidate causing this positive corr...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2019.00359
更新日期:2019-10-09 00:00:00
abstract::Musician's dystonia (MD) is a neurological motor disorder characterized by involuntary contractions of those muscles involved in the play of a musical instrument. It is task-specific and initially only impairs the voluntary control of highly practiced musical motor skills. MD can lead to a severe decrement in a musici...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00297
更新日期:2013-06-25 00:00:00
abstract::Background: Functional near-infrared spectroscopy (fNIRS) is a valuable neuroimaging approach for studying cortical contributions to walking function. Recruitment of prefrontal cortex during walking has been a particular area of focus in the literature. The present study investigated whether task-related change in pre...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2019.00194
更新日期:2019-06-18 00:00:00
abstract::Dopaminergic drugs frequently produce paradoxical effects depending on baseline performance levels, genotype, or personality traits. The present study for the first time aimed to specify the mechanisms underlying such opposite effects using the following recently reported scenario as an example: depending on the perso...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00117
更新日期:2013-04-08 00:00:00
abstract::Individuals with social anxiety disorder (SAD) are characterized by fear or anxiety about social situations, but also by important alterations in self-referential processing. Given advances in our understanding of the neurocircuitry and neurochemistry of SAD, the question arises of the relationship between this resear...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章,评审
doi:10.3389/fnhum.2015.00489
更新日期:2015-09-23 00:00:00
abstract::Reinforcement and use-dependent plasticity mechanisms have been proposed to be involved in both savings and anterograde interference in adaptation to a visuomotor rotation (cf. Huang et al., 2011). In Parkinson's disease (PD), dopamine dysfunction is known to impair reinforcement mechanisms, and could also affect use-...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00055
更新日期:2013-02-27 00:00:00
abstract::The frontal lobes are involved in many higher-order cognitive functions such as social cognition executive functions and language and speech. These functions are complex and follow a prolonged developmental course from childhood through to early adulthood. Magnetoencephalography (MEG) is ideal for the study of develop...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章,评审
doi:10.3389/fnhum.2014.00453
更新日期:2014-06-18 00:00:00
abstract::Sensitivity to regularities plays a crucial role in the acquisition of various linguistic features from spoken language input. Artificial grammar learning paradigms explore pattern recognition abilities in a set of structured sequences (i.e., of syllables or letters). In the present study, we investigated the function...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2016.00551
更新日期:2016-11-08 00:00:00
abstract::The present study was aimed at investigating different aspects of Executive Functions (EF) in children with Developmental Dyslexia (DD). A neuropsychological battery tapping verbal fluency, spoonerism, attention, verbal shifting, short-term and working memory was used to assess 60 children with DD and 65 with typical ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2014.00120
更新日期:2014-03-07 00:00:00
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journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00336
更新日期:2013-07-16 00:00:00
abstract::Optimizing rehabilitation strategies requires understanding the effects of contextual cues on adaptation learning. Prior studies have examined these effects on the specificity of split-belt walking adaptation, showing that contextual visual cues can be manipulated to modulate the magnitude, transfer, and washout of sp...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2017.00320
更新日期:2017-06-20 00:00:00
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journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2016.00572
更新日期:2016-11-23 00:00:00
abstract::The relationships between the anatomical representation of semantic knowledge in the human brain and the timing of neurophysiological mechanisms involved in manipulating such information remain unclear. This is the case for superordinate semantic categorization-the extraction of general features shared by broad classe...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00293
更新日期:2013-07-01 00:00:00
abstract::The human voice, which has a pivotal role in communication, is processed in specialized brain regions. Although a general consensus holds that the anterior insular cortex (AIC) plays a critical role in negative emotional experience, previous studies have not observed AIC activation in response to hearing disgust in vo...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2014.00743
更新日期:2014-09-22 00:00:00
abstract::Individuals differ substantially in their susceptibility to distraction by irrelevant visual information. Previous research has uncovered how individual variability in the goal-driven component of attentional control influences distraction, yet it remains unknown whether other sources of variability between individual...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2012.00012
更新日期:2012-02-15 00:00:00
abstract::[This corrects the article DOI: 10.3389/fnhum.2020.00095.]. ...
journal_title:Frontiers in human neuroscience
pub_type: 已发布勘误
doi:10.3389/fnhum.2020.00239
更新日期:2020-07-15 00:00:00
abstract::Behavioral and event-related potential (ERP) studies on aphasia patients showed that lexical information is not lost but rather its integration into the working context is hampered. Studies have been conducted on the processing of sentence-level information (meaningful versus meaningless) and of word-level information...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2016.00684
更新日期:2017-01-10 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a devastating disease with a lifetime risk of ∼1 in 2000. Presently, diagnosis of ALS relies on clinical assessments for upper motor neuron and lower motor neuron deficits in multiple body segments together with a history of progression of symptoms. In addition, it is common to e...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00251
更新日期:2013-06-10 00:00:00
abstract::[This corrects the article on p. 293 in vol. 8, PMID: 24860475.]. ...
journal_title:Frontiers in human neuroscience
pub_type: 已发布勘误
doi:10.3389/fnhum.2017.00097
更新日期:2017-02-28 00:00:00