Chemosensory Event-Related Potentials in Response to Nasal Propylene Glycol Stimulation.

Abstract:

:Propylene glycol, also denoted as 1.2 propanediol (C3H8O2), often serves as a solvent for dilution of olfactory stimuli. It is supposed to serve as a neutral substance and has been used in many behavioral and electrophysiological studies to dilute pure olfactory stimuli. However, the effect of propylene glycol on perception and on neuronal responses has hitherto never been studied. In this study we tested by means of a threshold test, whether a nasal propylene glycol stimulation is recognizable by humans. Participants were able to recognize propylene glycol at a threshold of 42% concentration and reported a slight cooling effect. In addition to the threshold test, we recorded electroencephalography (EEG) during nasal propylene glycol stimulation to study the neuronal processing of the stimulus. We used a flow olfactometer and stimulated 15 volunteers with three different concentrations of propylene glycol (40 trials each) and water as a control condition (40 trials). To evaluate the neuronal response, we analyzed the event-related potentials (ERPs) and power modulations. The task of the volunteers was to identify a change (olfactory, thermal, or tactile) in the continuous air flow generated by the flow olfactometer. The analysis of the ERPs showed that propylene glycol generates a clear P2 component, which was also visible in the frequency domain as an evoked power response in the theta-band. The source analysis of the P2 revealed a widespread involvement of brain regions, including the postcentral gyrus, the insula and adjacent operculum, the thalamus, and the cerebellum. Thus, it is possible that trigeminal stimulation can at least partly account for sensations and brain responses elicited by propylene glycol. Based on these results, we conclude that the use of high propylene glycol concentrations to dilute fragrances complicates the interpretation of presumed purely olfactory effects.

journal_name

Front Hum Neurosci

authors

Sirous M,Sinning N,Schneider TR,Friese U,Lorenz J,Engel AK

doi

10.3389/fnhum.2019.00099

subject

Has Abstract

pub_date

2019-03-20 00:00:00

pages

99

issn

1662-5161

journal_volume

13

pub_type

杂志文章
  • The Effect of Aging in Inhibitory Control of Major Depressive Disorder Revealed by Event-Related Potentials.

    abstract::Elderly depressed patients manifest pronounced executive dysfunction compared with younger subjects with depressive disorder. Aging-related brain changes may result in executive dysfunction in geriatric depression. We investigated the neural correlates of inhibitory control processing in depressed subjects at differen...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00116

    authors: Zhang BW,Xu J,Chang Y

    更新日期:2016-03-30 00:00:00

  • Secular Slowing of Auditory Simple Reaction Time in Sweden (1959-1985).

    abstract::There are indications that simple reaction time might have slowed in Western populations, based on both cohort- and multi-study comparisons. A possible limitation of the latter method in particular is measurement error stemming from methods variance, which results from the fact that instruments and experimental condit...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00407

    authors: Madison G,Woodley Of Menie MA,Sänger J

    更新日期:2016-08-18 00:00:00

  • Slow Is Also Fast: Feedback Delay Affects Anxiety and Outcome Evaluation.

    abstract::Performance-related feedback plays an important role in improving human being's adaptive behavior. Using event-related potentials (ERPs), previous studies have associated a particular component, i.e., reward positivity (RewP), with outcome evaluation processing and found that this component was affected by waiting tim...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00020

    authors: Zhang X,Lei Y,Yin H,Li P,Li H

    更新日期:2018-01-25 00:00:00

  • Brain-to-Brain Coupling in the Gamma-Band as a Marker of Shared Intentionality.

    abstract::Cooperation and competition are two ways of social interaction keys to life in society. Recent EEG-based hyperscanning studies reveal that cooperative and competitive interactions induce an increase in interbrain coupling. However, whether this interbrain coupling effect is just a reflection of inter-subject motor coo...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2020.00295

    authors: Barraza P,Pérez A,Rodríguez E

    更新日期:2020-07-30 00:00:00

  • Comparing Aging and Fitness Effects on Brain Anatomy.

    abstract::Recent studies suggest that cardiorespiratory fitness (CRF) mitigates the brain's atrophy typically associated with aging, via a variety of beneficial mechanisms. One could argue that if CRF is generally counteracting the negative effects of aging, the same regions that display the greatest age-related volumetric loss...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00286

    authors: Fletcher MA,Low KA,Boyd R,Zimmerman B,Gordon BA,Tan CH,Schneider-Garces N,Sutton BP,Gratton G,Fabiani M

    更新日期:2016-06-28 00:00:00

  • The Principle of Inverse Effectiveness in Audiovisual Speech Perception.

    abstract::We assessed how synchronous speech listening and lipreading affects speech recognition in acoustic noise. In simple audiovisual perceptual tasks, inverse effectiveness is often observed, which holds that the weaker the unimodal stimuli, or the poorer their signal-to-noise ratio, the stronger the audiovisual benefit. S...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00335

    authors: van de Rijt LPH,Roye A,Mylanus EAM,van Opstal AJ,van Wanrooij MM

    更新日期:2019-09-26 00:00:00

  • Individual visual working memory capacities and related brain oscillatory activities are modulated by color preferences.

    abstract::Subjective preferences affect many processes, including motivation, along with individual differences. Although incentive motivations are proposed to increase our limited visual working memory (VWM) capacity, much less is known about the effects of subjective preferences on VWM-related brain systems, such as the prefr...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2012.00318

    authors: Kawasaki M,Yamaguchi Y

    更新日期:2012-11-27 00:00:00

  • A Neurophysiological and Neuropsychological Consideration of Mindful Movement: Clinical and Research Implications.

    abstract::In this article, we present ideas related to three key aspects of mindfulness training: the regulation of attention via noradrenaline, the importance of working memory and its various components (particularly the central executive and episodic buffer), and the relationship of both of these to mind-wandering. These sam...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2015.00282

    authors: Russell TA,Arcuri SM

    更新日期:2015-05-26 00:00:00

  • The iconographic brain. A critical philosophical inquiry into (the resistance of) the image.

    abstract::The brain image plays a central role in contemporary image culture and, in turn, (co)constructs contemporary forms of subjectivity. The central aim of this paper is to probe the unmistakably potent interpellative power of brain images by delving into the power of imaging and the power of the image itself. This is not ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00300

    authors: De Vos J

    更新日期:2014-05-15 00:00:00

  • The cortical activation pattern by a rehabilitation robotic hand: a functional NIRS study.

    abstract:INTRODUCTION:Clarification of the relationship between external stimuli and brain response has been an important topic in neuroscience and brain rehabilitation. In the current study, using functional near infrared spectroscopy (fNIRS), we attempted to investigate cortical activation patterns generated during execution ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00049

    authors: Chang PH,Lee SH,Gu GM,Lee SH,Jin SH,Yeo SS,Seo JP,Jang SH

    更新日期:2014-02-06 00:00:00

  • A review of visual perspective taking in autism spectrum disorder.

    abstract::Impairments in social cognition are a key symptom of autism spectrum disorder (ASD). People with autism have great difficulty with understanding the beliefs and desires of other people. In recent years literature has begun to examine the link between impairments in social cognition and abilities which demand the use o...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2013.00652

    authors: Pearson A,Ropar D,de C Hamilton AF

    更新日期:2013-10-08 00:00:00

  • Repeating with the right hemisphere: reduced interactions between phonological and lexical-semantic systems in crossed aphasia?

    abstract::Knowledge on the patterns of repetition amongst individuals who develop language deficits in association with right hemisphere lesions (crossed aphasia) is very limited. Available data indicate that repetition in some crossed aphasics experiencing phonological processing deficits is not heavily influenced by lexical-s...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00675

    authors: De-Torres I,Dávila G,Berthier ML,Walsh SF,Moreno-Torres I,Ruiz-Cruces R

    更新日期:2013-10-18 00:00:00

  • Synaptic and cellular profile of neurons in the lateral habenula.

    abstract::The lateral habenula (LHb) is emerging as a crucial structure capable of conveying rewarding and aversive information. Recent evidence indicates that a rapid increase in the activity of LHb neurons drives negative states and avoidance. Furthermore, the hyperexcitability of neurons in the LHb, especially those projecti...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2013.00860

    authors: Meye FJ,Lecca S,Valentinova K,Mameli M

    更新日期:2013-12-16 00:00:00

  • Coupling brain-machine interfaces with cortical stimulation for brain-state dependent stimulation: enhancing motor cortex excitability for neurorehabilitation.

    abstract::Motor recovery after stroke is an unsolved challenge despite intensive rehabilitation training programs. Brain stimulation techniques have been explored in addition to traditional rehabilitation training to increase the excitability of the stimulated motor cortex. This modulation of cortical excitability augments the ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2014.00122

    authors: Gharabaghi A,Kraus D,Leão MT,Spüler M,Walter A,Bogdan M,Rosenstiel W,Naros G,Ziemann U

    更新日期:2014-03-05 00:00:00

  • Distinguishing Social From Private Intentions Through the Passive Observation of Gaze Cues.

    abstract::Observing others' gaze is most informative during social encounters between humans: We can learn about potentially salient objects in the shared environment, infer others' mental states and detect their communicative intentions. We almost automatically follow the gaze of others in order to check the relevance of the t...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00442

    authors: Jording M,Engemann D,Eckert H,Bente G,Vogeley K

    更新日期:2019-12-17 00:00:00

  • Dynamic Office Environments Improve Brain Activity and Attentional Performance Mediated by Increased Motor Activity.

    abstract::Current research demonstrates beneficial effects of physical activity on brain functions and cognitive performance. To date, less is known on the effects of gross motor movements that do not fall into the category of sports-related aerobic or anaerobic exercise. In previous studies, we found beneficial effects of dyna...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00121

    authors: Henz D,Schöllhorn WI

    更新日期:2019-04-12 00:00:00

  • Region-Specific Slowing of Alpha Oscillations is Associated with Visual-Perceptual Abilities in Children Born Very Preterm.

    abstract::Children born very preterm (≤32 weeks gestational age) without major intellectual or neurological impairments often express selective deficits in visual-perceptual abilities. The alterations in neurophysiological development underlying these problems, however, remain poorly understood. Recent research has indicated th...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00791

    authors: Doesburg SM,Moiseev A,Herdman AT,Ribary U,Grunau RE

    更新日期:2013-11-15 00:00:00

  • Cortical microcircuit dynamics mediating binocular rivalry: the role of adaptation in inhibition.

    abstract::Perceptual bistability arises when two conflicting interpretations of an ambiguous stimulus or images in binocular rivalry (BR) compete for perceptual dominance. From a computational point of view, competition models based on cross-inhibition and adaptation have shown that noise is a crucial force for rivalry, and ope...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00145

    authors: Theodoni P,Panagiotaropoulos TI,Kapoor V,Logothetis NK,Deco G

    更新日期:2011-11-28 00:00:00

  • Strong Relation Between an EEG Functional Connectivity Measure and Postmenstrual Age: A New Potential Tool for Measuring Neonatal Brain Maturation.

    abstract::Fetal and neonatal brain connectivity development is highly complex. Studies have shown that functional networks change dramatically during development. The purpose of the current study was to determine how the mean phase lag index (mPLI), a measure of functional connectivity (FC), assessed with electroencephalography...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00286

    authors: van de Pol LA,van 't Westende C,Zonnenberg I,Koedam E,van Rossum I,de Haan W,Steenweg M,van Straaten EC,Stam CJ

    更新日期:2018-07-17 00:00:00

  • The Dancing Brain: Structural and Functional Signatures of Expert Dance Training.

    abstract::Dance - as a ritual, therapy, and leisure activity - has been known for thousands of years. Today, dance is increasingly used as therapy for cognitive and neurological disorders such as dementia and Parkinson's disease. Surprisingly, the effects of dance training on the healthy young brain are not well understood desp...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00566

    authors: Burzynska AZ,Finc K,Taylor BK,Knecht AM,Kramer AF

    更新日期:2017-11-27 00:00:00

  • The Effects of Transcranial Direct Current Stimulation (tDCS) on Working Memory Training in Healthy Young Adults.

    abstract::Working memory (WM) is a fundamental cognitive ability to support complex thought, but it is limited in capacity. WM training has shown the potential benefit for those in need of a higher WM ability. Many studies have shown the potential of transcranial direct current stimulation (tDCS) to transiently enhance WM perfo...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00019

    authors: Ke Y,Wang N,Du J,Kong L,Liu S,Xu M,An X,Ming D

    更新日期:2019-02-01 00:00:00

  • Comparing the neural distance effect derived from the non-symbolic comparison and the same-different task.

    abstract::As a result of the representation of numerosities, more accurate and faster discrimination between two numerosities is observed when the distance between them increases. In previous studies, the comparison and same-different task were most frequently used to investigate this distance effect. Recently, it was questione...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00028

    authors: Smets K,Gebuis T,Reynvoet B

    更新日期:2013-02-14 00:00:00

  • Hyperactivation of the habenula as a link between depression and sleep disturbance.

    abstract::Depression occurs frequently with sleep disturbance such as insomnia. Sleep in depression is associated with disinhibition of the rapid eye movement (REM) sleep. Despite the coincidence of the depression and sleep disturbance, neural substrate for depressive behaviors and sleep regulation remains unknown. Habenula is ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章,评审

    doi:10.3389/fnhum.2013.00826

    authors: Aizawa H,Cui W,Tanaka K,Okamoto H

    更新日期:2013-12-10 00:00:00

  • Neural Correlates of Mirror Visual Feedback-Induced Performance Improvements: A Resting-State fMRI Study.

    abstract::Mirror visual feedback (MVF) is a promising approach to enhance motor performance without training in healthy adults as well as in patients with focal brain lesions. There is preliminary evidence that a functional modulation within and between primary motor cortices as assessed with transcranial magnetic stimulation (...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2017.00054

    authors: Rjosk V,Lepsien J,Kaminski E,Hoff M,Sehm B,Steele CJ,Villringer A,Ragert P

    更新日期:2017-02-06 00:00:00

  • Fronto-Temporal Circuits in Musical Hallucinations: A PET-MR Case Study.

    abstract::The aim of the study is to investigate morphofunctional circuits underlying musical hallucinations (MH) in a 72-years old female that underwent a simultaneous 18fluoredeoxyglucose positron emission tomography (PET) and advanced magnetic resonance (MR) exam. This represents a particular case of MH occurred in an health...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2018.00385

    authors: Cavaliere C,Longarzo M,Orsini M,Aiello M,Grossi D

    更新日期:2018-09-27 00:00:00

  • Contributions of Sensory Coding and Attentional Control to Individual Differences in Performance in Spatial Auditory Selective Attention Tasks.

    abstract::Listeners with normal hearing thresholds (NHTs) differ in their ability to steer attention to whatever sound source is important. This ability depends on top-down executive control, which modulates the sensory representation of sound in the cortex. Yet, this sensory representation also depends on the coding fidelity o...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00530

    authors: Dai L,Shinn-Cunningham BG

    更新日期:2016-10-20 00:00:00

  • Informational connectivity: identifying synchronized discriminability of multi-voxel patterns across the brain.

    abstract::The fluctuations in a brain region's activation levels over a functional magnetic resonance imaging (fMRI) time-course are used in functional connectivity (FC) to identify networks with synchronous responses. It is increasingly recognized that multi-voxel activity patterns contain information that cannot be extracted ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2013.00015

    authors: Coutanche MN,Thompson-Schill SL

    更新日期:2013-02-07 00:00:00

  • The insular taste cortex contributes to odor quality coding.

    abstract::Despite distinct peripheral and central pathways, stimulation of both the olfactory and the gustatory systems may give rise to the sensation of sweetness. Whether there is a common central mechanism producing sweet quality sensations or two discrete mechanisms associated independently with gustatory and olfactory stim...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00058

    authors: Veldhuizen MG,Nachtigal D,Teulings L,Gitelman DR,Small DM

    更新日期:2010-07-21 00:00:00

  • The Relationship Between Heart Rate Variability and Electroencephalography Functional Connectivity Variability Is Associated With Cognitive Flexibility.

    abstract::The neurovisceral integration model proposes a neuronal network that is related to heart rate activity and cognitive performance. The aim of this study was to determine whether heart rate variability (HRV) and variability in electroencephalographic (EEG) functional connectivity in the resting state are related to cogn...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2019.00064

    authors: Alba G,Vila J,Rey B,Montoya P,Muñoz MÁ

    更新日期:2019-02-25 00:00:00

  • Comparing the Neural Correlates of Conscious and Unconscious Conflict Control in a Masked Stroop Priming Task.

    abstract::Although previous studies have suggested that conflict control can occur in the absence of consciousness, the brain mechanisms underlying unconscious and conscious conflict control remain unclear. The current study used a rapid event-related functional magnetic resonance imaging design to collect data from 24 particip...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2016.00297

    authors: Jiang J,Bailey K,Xiang L,Zhang L,Zhang Q

    更新日期:2016-06-20 00:00:00