Abstract：
OBJECTIVE:The main drug used against Hymenolepis nana is praziquantel (PZQ), which causes side effects and toxicity. In contrast, natural extracts have limited side effects and are safer. Past researches have proved that pumpkin seeds are effective as natural antimicrobial and antiparasitic treatment. The present study investigates a natural alternative and less expensive treatment against H. nana using pumpkin seeds. MATERIALS AND METHODS:Healthy female albino mice were divided into four groups: normal control, infected control with H. nana, infected and treated with PZQ, and lastly, the group infected and treated with pumpkin seeds' extract. RESULTS:Pumpkin seeds aqueous extract showed a significant reduction (P < 0.05) in the number and length of H. nana adult worms, number and viability of eggs in comparison to the infected control group and PZQ group. Pumpkin seed aqueous extract is proven to be an effective anthelmintic against H. nana. CONCLUSION:We recommend pumpkin seed extract as a natural alternative, less expensive and safe therapy for H. nana. This is the first study in Saudi Arabia to investigate the therapeutic effect of pumpkin seeds' extract on H. nana.
journal_name
Acta Parasitoljournal_title
Acta parasitologicaauthors
Alhawiti AO,Toulah FH,Wakid MHdoi
10.2478/s11686-019-00033-zsubject
Has Abstractpub_date
2019-06-01 00:00:00pages
276-281issue
2eissn
1230-2821issn
1896-1851pii
10.2478/s11686-019-00033-zjournal_volume
64pub_type
杂志文章abstract：:The effects of 5, 20, and 40 miracidia dose exposures of Echinostoma caproni on the amino acid contents of Biomphalaria glabrata were studied using high performance thin-layer chromatography-densitometry. Amino acids were identified and quantified in whole bodies of exposed snails and in the uninfected matched control...
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更新日期：2018-06-26 00:00:00
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pub_type： 杂志文章
doi：10.2478/s11686-019-00151-8
更新日期：2020-03-01 00:00:00
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journal_title：Acta parasitologica
pub_type： 杂志文章
doi：10.2478/s11686-020-00180-8
更新日期：2020-09-01 00:00:00
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journal_title：Acta parasitologica
pub_type： 杂志文章
doi：10.2478/s11686-012-0033-6
更新日期：2012-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-12-20 00:00:00
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doi：10.2478/s11686-013-0168-0
更新日期：2013-12-01 00:00:00
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更新日期：2014-09-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2018-03-26 00:00:00
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journal_title：Acta parasitologica
pub_type： 杂志文章
doi：10.2478/s11686-014-0209-3
更新日期：2014-03-01 00:00:00
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更新日期：2012-09-01 00:00:00
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更新日期：2020-12-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-07-20 00:00:00
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pub_type： 杂志文章
doi：10.2478/s11686-014-0279-2
更新日期：2014-10-01 00:00:00
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更新日期：2016-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2015-09-01 00:00:00
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更新日期：2013-06-01 00:00:00
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更新日期：2015-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2013-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
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journal_title：Acta parasitologica
pub_type： 杂志文章
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更新日期：2017-09-26 00:00:00
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pub_type： 杂志文章
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更新日期：2018-06-26 00:00:00
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journal_title：Acta parasitologica
pub_type： 杂志文章
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更新日期：2020-09-15 00:00:00
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journal_title：Acta parasitologica
pub_type： 杂志文章
doi：10.1007/s11686-020-00303-1
更新日期：2020-11-08 00:00:00
abstract：:PURPOSE : The present study aimed to investigate the amoebicidal and amoebistatic efects of Artemisia argyi leaf methanolic extract by testing the effects on trophozoites and on cysts. We also determined cytotoxic effect, enzymatic and non-enzymatic antioxidant activities, total phenolic, lavonoid and antioxidative co...
journal_title：Acta parasitologica
pub_type： 杂志文章
doi：10.2478/s11686-018-00009-5
更新日期：2019-03-01 00:00:00
abstract：INTRODUCTION:Trichinellosis is a severe zoonosis involving the activation of inflammatory cells, accompanied by the prominent expressions of proinflammatory cytokines in the host. Semen vaccariae, the seeds of Vaccaria segetalis (Neck.) Garcke. ex Asch. (Caryophyllaceae), is a famous traditional herb that is rich in va...
journal_title：Acta parasitologica
pub_type： 杂志文章
doi：10.2478/s11686-019-00064-6
更新日期：2019-09-01 00:00:00
