当前位置： SCI文献检索 > CRITICAL CARE MEDICINE期刊下所有文献 > Use of therapeutic hypothermia after in-hospital cardiac arrest.

Use of therapeutic hypothermia after in-hospital cardiac arrest.

Abstract：

OBJECTIVES:Formal guidelines recommend that therapeutic hypothermia be considered after in-hospital cardiac arrest. The rate of therapeutic hypothermia use after in-hospital cardiac arrest and details about its implementation are unknown. We aimed to determine the use of therapeutic hypothermia for adult in-hospital cardiac arrest, whether use has increased over time, and to identify factors associated with its use. DESIGN:Multicenter, prospective cohort study. SETTING:A total of 538 hospitals participating in the Get With the Guidelines-Resuscitation database (2003-2009). PATIENTS:A total of 67,498 patients who had return of spontaneous circulation after in-hospital cardiac arrest. INTERVENTIONS:None. MEASUREMENTS AND MAIN RESULTS:The primary outcome was the initiation of therapeutic hypothermia. We measured the proportion of therapeutic hypothermia patients who achieved target temperature (32-34 °C) and were overcooled. Of 67,498 patients, therapeutic hypothermia was initiated in 1,367 patients (2.0%). The target temperature (32-34 °C) was not achieved in 44.3% of therapeutic hypothermia patients within 24 hours and 17.6% were overcooled. The use of therapeutic hypothermia increased from 0.7% in 2003 to 3.3% in 2009 (p < 0.001). We found that younger age (p < 0.001) and occurrence in a non-ICU location (p < 0.001), on a weekday (p = 0.005), and in a teaching hospital (p = 0.001) were associated with an increased likelihood of therapeutic hypothermia being initiated. CONCLUSIONS:After in-hospital cardiac arrest, therapeutic hypothermia was used rarely. Once initiated, the target temperature was commonly not achieved. The frequency of use increased over time but remained low. Factors associated with therapeutic hypothermia use included patient age, time and location of occurrence, and type of hospital.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

Mikkelsen ME,Christie JD,Abella BS,Kerlin MP,Fuchs BD,Schweickert WD,Berg RA,Mosesso VN,Shofer FS,Gaieski DF,American Heart Association’s Get With the Guidelines-Resuscitation Investigators.

doi

10.1097/CCM.0b013e318287f2c4

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

1385-95

issue

eissn

0090-3493

issn

1530-0293

journal_volume

pub_type

杂志文章,多中心研究

在线工具

Use of therapeutic hypothermia after in-hospital cardiac arrest.