Abstract:
BACKGROUND:Incision and drainage of perianal sepsis has appreciable success in the immunocompetent population, but outcomes after incision and drainage in the immunosuppressed population are unknown. METHODS:13,666 patients (n = 930 immunosuppressed) undergoing incision and drainage of perianal sepsis between 2011 and 2015 in the American College of Surgeons National Surgical Quality Improvement Program were identified. The main outcomes were major morbidity, return to the operating room, and mortality. Multivariable analysis was performed for each outcome. RESULTS:Sepsis was the most common postoperative complication. Preoperative immunosuppression was an independent risk factor for major morbidity (odds ratio [OR]: 1.6, p < 0.01), return to the operating room (OR: 1.9, p < 0.01), and mortality (OR: 2.6, p < 0.01). CONCLUSIONS:Immunosuppression is an independent risk factor for major morbidity, return to the operating room, and mortality. With post-operative sepsis the most common complication, inpatient admission and extended duration antibiotic therapy is warranted in immunosuppressed patients.
journal_name
Am J Surgjournal_title
American journal of surgeryauthors
McKenna NP,Bews KA,Shariq OA,Habermann EB,Cima RR,Lightner ALdoi
10.1016/j.amjsurg.2019.01.036subject
Has Abstractpub_date
2019-09-01 00:00:00pages
507-513issue
3eissn
0002-9610issn
1879-1883pii
S0002-9610(18)31520-4journal_volume
218pub_type
杂志文章abstract::A prospective clinical trial was designed to evaluate the efficacy of postoperative jejunostomy feedings using high (44 percent) and low (15 percent) branched-chain amino acid elemental diet formulations compared with no jejunostomy feedings in a homogeneous surgical population. Twenty-eight patients undergoing radica...
journal_title:American journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American journal of surgery
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pub_type: 杂志文章
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