Incision & drainage of perianal sepsis in the immunocompromised: A need for heightened postoperative awareness.

Abstract:

BACKGROUND:Incision and drainage of perianal sepsis has appreciable success in the immunocompetent population, but outcomes after incision and drainage in the immunosuppressed population are unknown. METHODS:13,666 patients (n = 930 immunosuppressed) undergoing incision and drainage of perianal sepsis between 2011 and 2015 in the American College of Surgeons National Surgical Quality Improvement Program were identified. The main outcomes were major morbidity, return to the operating room, and mortality. Multivariable analysis was performed for each outcome. RESULTS:Sepsis was the most common postoperative complication. Preoperative immunosuppression was an independent risk factor for major morbidity (odds ratio [OR]: 1.6, p < 0.01), return to the operating room (OR: 1.9, p < 0.01), and mortality (OR: 2.6, p < 0.01). CONCLUSIONS:Immunosuppression is an independent risk factor for major morbidity, return to the operating room, and mortality. With post-operative sepsis the most common complication, inpatient admission and extended duration antibiotic therapy is warranted in immunosuppressed patients.

journal_name

Am J Surg

authors

McKenna NP,Bews KA,Shariq OA,Habermann EB,Cima RR,Lightner AL

doi

10.1016/j.amjsurg.2019.01.036

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

507-513

issue

3

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(18)31520-4

journal_volume

218

pub_type

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