Abstract:
INTRODUCTION:Diabetes has been repeatedly associated with a wide variety of cognitive impairments. AIM:To clarify the differences in cognitive dysfunctions between the two types of diabetes. METHOD:Metaanalysis was performed using databases of Medline, PubMed and ScienceDirect (3 studies with type 1 and 6 with type 2 diabetes). RESULTS:Adults with type 1 diabetes showed lower performance than control subjects in all fields. The effect size had the highest value in psychomotor activity (D = -0.69). The effect size was small for delayed verbal memory (D = -0.48), attention (D = -0.47), language (D = -0.44), visual processing (D = -0.35), immediate verbal memory (D = -0.30), working memory (D = -0.27) and executive functions (D = -0.26). Adults with type 2 diabetes showed lower performance than control subjects in all cognitive domains, except for working memory (D = +0.03). The effect size had the highest value in immediate verbal memory (D = -1.12), psychomotor activity (D = -0.82) and delayed verbal memory (D = -0.81). The effect size was moderate for general intellectual abilities (D = -0.68) and small for general memory (D = -0.37), attention (D = -0.35), language (D = -0.35), visual processing (D = -0.33) and executive functions (D = -0.33). CONCLUSION:Both types of diabetes are associated with reduced performance in numerous cognitive domains. :Bevezetés: A cukorbetegséget különféle kognitív károsodásokkal társítják. Célkitűzés: A szerzők 1-es és 2-es típusú diabetesben a kognitív működés közötti különbségek pontosítását tűzték ki célul. Módszer: Metaanalízis a Medline, PubMed és ScienceDirect felhasználásával (három tanulmány az 1-es és hat tanulmány a 2-es típusú cukorbetegséggel kapcsolatban). Eredmények: Az 1-es típusú cukorbeteg felnőttek teljesítménye gyengébb volt a kontrollokhoz képest az összes mért területen. A hatásméret a pszichomotoros aktivitásnál volt a legmagasabb (D = –0,69). Kicsi volt a hatásméret a késleltetett verbális memória (D = –0,48), figyelem (D = –0,47), nyelv (D = –0,44), vizuális feldolgozás (D = –0,35), azonnali verbális memória (D = –0,30), munkamemória (D = –0,27) és a végrehajtó funkcióknál (D = –0,26). A felnőtt 2-es típusú cukorbetegek teljesítménye gyengébb volt, mint a kontrolloké a munkamemória kivételével (D = +0,03) az összes kognitív területen. Legmagasabb hatásméretet az azonnali verbális memória (D = –1,12), pszichomotoros aktivitás (D = –0,82) és a késleltetett verbális memória (D = –0,81) mutatott. Közepes volt a hatásméret az általános intellektuális képességek (D = –0,68) területén, míg kicsi volt a hatásméret az általános memória (D = –0,37), a figyelem (D = –0,35), nyelv (D = –0,35), vizuális feldolgozás (D = –0,33) és a végrehajtó funkciók (D = –0,33) terén. Következtetés: Mindkét típusú cukorbetegség csökkent teljesítménnyel társul számos kognitív területen. Orv. Hetil., 2013, 154, 694–699.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Kálcza-Jánosi K,Lukács A,Barkai L,Szamosközi Idoi
10.1556/OH.2013.29602subject
Has Abstractpub_date
2013-05-05 00:00:00pages
694-9issue
18eissn
0030-6002issn
1788-6120pii
Q6R050VU8J792808journal_volume
154pub_type
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