[Cognitive functions in type 1 and type 2 diabetes. Meta-analysis].

Abstract:

INTRODUCTION:Diabetes has been repeatedly associated with a wide variety of cognitive impairments. AIM:To clarify the differences in cognitive dysfunctions between the two types of diabetes. METHOD:Metaanalysis was performed using databases of Medline, PubMed and ScienceDirect (3 studies with type 1 and 6 with type 2 diabetes). RESULTS:Adults with type 1 diabetes showed lower performance than control subjects in all fields. The effect size had the highest value in psychomotor activity (D = -0.69). The effect size was small for delayed verbal memory (D = -0.48), attention (D = -0.47), language (D = -0.44), visual processing (D = -0.35), immediate verbal memory (D = -0.30), working memory (D = -0.27) and executive functions (D = -0.26). Adults with type 2 diabetes showed lower performance than control subjects in all cognitive domains, except for working memory (D = +0.03). The effect size had the highest value in immediate verbal memory (D = -1.12), psychomotor activity (D = -0.82) and delayed verbal memory (D = -0.81). The effect size was moderate for general intellectual abilities (D = -0.68) and small for general memory (D = -0.37), attention (D = -0.35), language (D = -0.35), visual processing (D = -0.33) and executive functions (D = -0.33). CONCLUSION:Both types of diabetes are associated with reduced performance in numerous cognitive domains. :Bevezetés: A cukorbetegséget különféle kognitív károsodásokkal társítják. Célkitűzés: A szerzők 1-es és 2-es típusú diabetesben a kognitív működés közötti különbségek pontosítását tűzték ki célul. Módszer: Metaanalízis a Medline, PubMed és ScienceDirect felhasználásával (három tanulmány az 1-es és hat tanulmány a 2-es típusú cukorbetegséggel kapcsolatban). Eredmények: Az 1-es típusú cukorbeteg felnőttek teljesítménye gyengébb volt a kontrollokhoz képest az összes mért területen. A hatásméret a pszichomotoros aktivitásnál volt a legmagasabb (D = –0,69). Kicsi volt a hatásméret a késleltetett verbális memória (D = –0,48), figyelem (D = –0,47), nyelv (D = –0,44), vizuális feldolgozás (D = –0,35), azonnali verbális memória (D = –0,30), munkamemória (D = –0,27) és a végrehajtó funkcióknál (D = –0,26). A felnőtt 2-es típusú cukorbetegek teljesítménye gyengébb volt, mint a kontrolloké a munkamemória kivételével (D = +0,03) az összes kognitív területen. Legmagasabb hatásméretet az azonnali verbális memória (D = –1,12), pszichomotoros aktivitás (D = –0,82) és a késleltetett verbális memória (D = –0,81) mutatott. Közepes volt a hatásméret az általános intellektuális képességek (D = –0,68) területén, míg kicsi volt a hatásméret az általános memória (D = –0,37), a figyelem (D = –0,35), nyelv (D = –0,35), vizuális feldolgozás (D = –0,33) és a végrehajtó funkciók (D = –0,33) terén. Következtetés: Mindkét típusú cukorbetegség csökkent teljesítménnyel társul számos kognitív területen. Orv. Hetil., 2013, 154, 694–699.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Kálcza-Jánosi K,Lukács A,Barkai L,Szamosközi I

doi

10.1556/OH.2013.29602

subject

Has Abstract

pub_date

2013-05-05 00:00:00

pages

694-9

issue

18

eissn

0030-6002

issn

1788-6120

pii

Q6R050VU8J792808

journal_volume

154

pub_type

杂志文章,meta分析
  • [Pharmacological reduction of bleeding during hip endoprosthetic replacement].

    abstract:INTRODUCTION:Endoprosthetic replacement of the large joints is accompanied by major bleeding. During the last few years several authors reported the perioperative administration of tranexamic acid and its beneficial effect on reducing the blood loss. OBJECTIVES:In the present study, the author studied the effect of in...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2012.29455

    authors: de Jonge T

    更新日期:2012-10-14 00:00:00

  • [Frequency of hyperhomocysteinemia in hemodialysis patients with folic acid supplementation].

    abstract:BACKGROUND:It is known that hyperhomocystinemia is an independent risk factor for development of atherosclerosis. In end stage renal disease the frequency of hyperhomocystinemia is much greater than in normal populations. AIM:In this study homocystein (Hcy), folic acid and vitamin B12 concentrations were determined in...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Kárpáti I,Balla J,Szóke G,Bereczky Z,Páll D,Ben T,Toma K,Katona E,Mohácsi A,Paragh G,Varga Z,Kakuk G,Muszbek L

    更新日期:2002-07-07 00:00:00

  • [Role of ultrasonography in the urgent differential diagnosis of acute scrotum].

    abstract:UNLABELLED:Acute scrotum, when testicular torsion is suspected, needs emergency exploration. However, acute scrotum caused by torsion of the Morgagni hydatid and epididymitis can be managed conservatively. Real time colour Doppler ultrasound is becoming a more and more popular tool in the differential diagnosis, howeve...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2011.29129

    authors: Sándor L,Gajda T,Aranyi V,Csízy I,Cserni T

    更新日期:2011-06-05 00:00:00

  • [The pathology of hepatitis C].

    abstract::The hepatitis C virus is an RNA virus, which belongs to the genus Hepaciviruses of the family Flaviviridae. Chronic hepatitis, cirrhosis, and ultimately even liver cancer may develop in over 80% of infected cases. The histological features of hepatitis C and hepatitis caused by other hepatotropic viruses show many sim...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/650.2015.30178

    authors: Schaff Z,Gógl A,Dóra R,Halász T

    更新日期:2015-05-24 00:00:00

  • [Treatment of pregnancy associated breast cancer].

    abstract::Pregnancy-associated breast cancer (PABC) is defined as cancer of the breast diagnosed during pregnancy and up to 1 year postpartum. The crude incidence is 1/3000 pregnant women. As women delay childbearing the incidence of PABC increases with age. Young patients with PABC do not have worse prognosis compared with tho...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2010.28886

    authors: Székely B,Langmár Z,Somlai K,Szentmártoni G,Szalay K,Korompay A,Szász AM,Kulka J,Bánhidy F,Dank M

    更新日期:2010-08-08 00:00:00

  • [Cardiac resynchronization therapy for patients with atrial fibrillation].

    abstract::Atrial fibrillation and chronic heart failure are two major and even growing cardiovascular conditions that often coexist. Cardiac resynchronization therapy is an important, device-based, non-pharmacological approach in a selected group of chronic heart failure patients that has been shown to improve left ventricular ...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2011.29204

    authors: Mihálcz A,Abrahám P,Kardos A,Földesi C,Szili-Török T

    更新日期:2011-10-30 00:00:00

  • [Principles of the EOS™ X-ray machine and its use in daily orthopedic practice].

    abstract::The EOS™ X-ray machine, based on a Nobel prize-winning invention in Physics in the field of particle detection, is capable of simultaneously capturing biplanar X-ray images by slot scanning of the whole body in an upright, physiological load-bearing position, using ultra low radiation doses. The simultaneous capture o...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2012.29312

    authors: Illés T,Somoskeöy S

    更新日期:2012-02-26 00:00:00

  • [Vitamin D metabolism and osteoporosis in systemic sclerosis].

    abstract::In the past few years more and more data have become available on the important role of vitamin D in immunological processes and inflammation. The role of vitamin D deficiency in the pathogenesis as well as in disease progression of different autoimmune and inflammatory conditions is suspected. Vitamin D deficiency is...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/650.2017.30816

    authors: Szamosi S,Horváth Á,Szekanecz Z,Szűcs G

    更新日期:2017-08-01 00:00:00

  • [Role of blood glucose in prediction of cardiovascular risk].

    abstract::Increased cardiovascular risk in diabetes mellitus has been well-documented. In contrast, it is not widely known, that the relation between degree of hyperglycemia and mortality of diabetics or nondiabetics with acute coronary syndromes (ACS) shows a positive correlation. Insulin treatment significantly improves survi...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Simon K,Szépvölgyi A,Dobó E,Szabó A

    更新日期:2006-01-22 00:00:00

  • [Percutaneous transluminal valvuloplasty in severe neonatal pulmonary stenosis].

    abstract::The authors made diagnosis of valvar pulmonary stenosis in a 1-day old neonate. The severe stenosis was treated by means of pulmonary balloon valvuloplasty at the age of 4 days. The initial suprasystemic pressure in the right ventricle decreased to normal after the procedure. Transluminal balloon valvuloplasty is an e...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Masszi G,Szatmári A

    更新日期:1996-04-07 00:00:00

  • Coarctatio aortae: management from infancy to adulthood.

    abstract::The surgical management of congenital heart defects is changing continuously due to technical development. Aortic coarctation is one of the most frequent congenital heart diseases often with serious symptoms. The authors review the different surgical techniques (end-to-end anastomosis, pathplasty, interposition) and p...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/650.2020.31730

    authors: Hartyánszky I,Varga S,Hartyánszky I,Bogáts G

    更新日期:2020-05-01 00:00:00

  • [Primary, definitive treatment of the nasoethmoidorbital-midface-frontobasal injuries in the maxillofacial practice].

    abstract::Nasoethmoid-orbital (NEO) fractures are typically resulted by a drastic, forceful blow to the central aspect of the head and nose, associated injuries to adjacent structures occur and involve the midface, anterior cranial fossa and the eye. Dislocated bony parts of the nose may be impacted into the intraorbital region...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2009.28644

    authors: Nemes I,Pácz M,Rothy A,Erményi I,Kocsis C

    更新日期:2009-10-25 00:00:00

  • [Postischemic inverted T waves: does gradual regression indicate improved prognosis?].

    abstract::This study has followed up the natural history of postischemic inverted T waves and assessed the prognosis. 40 consecutive patients with unstable angina with postischemic precordial inverted T waves in the noninfarcted, previously ischemic area were followed during the persistence (negative T wave period) and after re...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Simon K,Turi T,Szabó P,Szelier A,Szépvölgyi A,Sereg M,Szatmáry L

    更新日期:1993-12-05 00:00:00

  • [Possibilities of non-hormonal drug treatment of osteoporosis].

    abstract::In many countries osteoporosis is the most common metabolic bone diseases. A great deal is known about the pathophysiology and the treatment of the disease. There is a lot of treatment possibilities and many new treatments are being tested. Therapeutic agents for osteoporosis are correspondingly classified as substanc...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Szathmári M,Châtel R

    更新日期:1999-09-19 00:00:00

  • [Restricted antibody diversity after bone marrow transplantation--homogeneous immunoglobulins].

    abstract::After bone marrow transplantation, a prolonged dysregulation of humoral immunity, including restricted electrophoretic heterogeneity of serum immunoglobulins and the appearance of homogeneous immunoglobulin components, can be observed. The current study was undertaken to characterize further and define the posttranspl...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Puskás E,Hajdu M,Barta A,Sipos A,Uher F,Pálóczi K

    更新日期:2001-02-11 00:00:00

  • [Neonatal hypoxic myocardial lesion].

    abstract::Five patients suffering from transient myocardial ischemia of the newborn are discussed. The role of two-dimensional doppler-echocardiography is emphasized in establishing the diagnosis. Tricuspid insufficiency due to perinatal asphyxia can be detected easier by ultrasound than by any other cardiac examination. Cardia...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Katona M

    更新日期:1991-02-03 00:00:00

  • [Long-term follow-up after tympanostomy tube insertion in children with serous otitis media].

    abstract:INTRODUCTION:The authors report about the efficacy of inserted tympanostomy tube in children with serous otitis media. AIM:The aim of the authors was to assess the status of eardrum, the function of Eustachian tube and hearing level 10 years after the use of tympanostomy tube. METHOD:Patients filled out a questionnai...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2015.30291

    authors: Fekete-Szabó G,Kiss F,Rovó L

    更新日期:2015-11-15 00:00:00

  • [Inclusion body myositis pathomechanism and therapy].

    abstract::Inclusion body myositis is an acquired inflammatory muscle disease belonging to the family of idiopathic inflammatory myopathy with vacuole formation. Approximately 15-28% of idiopathic inflammatory myopathy patients suffer from inclusion body myositis. Early diagnosis is very important due to the slowly progressive d...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:10.1556/OH.2008.28070

    authors: Váncsa A,Dankó K

    更新日期:2008-07-27 00:00:00

  • [Disorders of hemostatic system in patients with malignant disease, especially in view of venous thromboembolism].

    abstract:INTRODUCTION:An increased susceptibility to thrombosis demonstrated in laboratory analysis of solid malignant diseases develops as a result of the activating effect of malignant cells on the hemostatic system. The development of this activating effect is a consequence of interactions between malignant cells and the var...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2007.28130

    authors: Bozóky G,Ruby E,Góhér I,Mohos A,Bálint C,Bozóky I

    更新日期:2007-09-09 00:00:00

  • [Presence of antibodies to human herpesvirus type 6 and 7 in Hungarian children].

    abstract::Prevalence of antibodies to variants HHV-6A and B as well as HHV-7, the time of primary infections are not know in Hungarian children. Therefore, antibodies to these viruses were studied in 21 healthy children aged between 6 and 18 months. Lymphoid cultures were infected with standard virus strains for indirect immuno...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Ongrádi J,Csiszár A,Maródi CL,Sólyom J,Horváth A,Menezes J

    更新日期:1999-04-25 00:00:00

  • [Effectiveness of generic rosuvastatin in patients with ischaemic cerebrovascular disease].

    abstract:UNLABELLED:Statin therapy is the cornerstone of anti-atherosclerotic treatment, and it considered obligatory in the secondary prevention of atherosclerotic diseases. Rosuvastatin is well-known and efficacious lipid-lowering agent. Generic drugs are more frequently used instead of its ancestors. Generic rosuvastatin for...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2012.29390

    authors: Szapáry L,Fehér G

    更新日期:2012-06-03 00:00:00

  • [2-year results of leg amputation in Hungary based on a nationwide data base].

    abstract::Authors review nation-wide hospital data of amputees over two years in order to make comparison with similar data gathered about 20 years ago. Data were provided by the National Medical Records Centre and processed by own developed programmes. The quality level of data validity is slightly criticised. The cause of amp...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Kullmann L,Belicza E,László G

    更新日期:1997-09-14 00:00:00

  • [Surgical implications of chronic liver diseases].

    abstract::Complications of chronic liver diseases requiring surgical interventions are the following: esophageal varices and bleeding, ascites hypersplenism, some forms of liver insufficiency. The most widely accepted method for treatment of esophageal varices is endoscopic sclerotherapy. Portal systemic shunts are indicated in...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章,评审

    doi:

    authors: Kupcsulik P

    更新日期:1992-08-09 00:00:00

  • [Endemic hepatitis E infections in South-East Hungary].

    abstract:INTRODUCTION:Hepatitis E virus (HEV) one of the most important infectious agent in acute hepatitis in tropical and subtropical areas. Recently, it has been demonstrated that HEV infection also occur in developed countries without travel history. In these regions, transmission thought to be zoonotic. In this work hepati...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Fodor D,Kátai A,Reuter G,Maszárovics Z,Menyhárth E

    更新日期:2005-11-06 00:00:00

  • [Health related costs of smoking from the viewpoint of the Health Insurance Fund in Hungary].

    abstract:UNLABELLED:In recent times, the topic of smoking has been extensively debated in Hungary. A new Act has been issued for the protection of non-smokers and for the regulation of tobacco product distribution. AIMS:The aim of the authors was to examine the economic burden of smoking on the society. METHODS:According to w...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2012.29280

    authors: Gresz M,Nagy J,Freyler P

    更新日期:2012-03-04 00:00:00

  • [Effect of fructose-1,6-diphosphate on myocardial purin and pyrimidin metabolism during coronary artery bypass grafting surgery].

    abstract::During ischaemia, the glycolytic pathway (Embden-Meyerhof) is up regulated in an attempt to produce ATP anaerobically. However, this is short-lived due to negative feedback on the key glycolytic enzyme phosphofructokinase by accumulating lactate. Fructose-1,6-diphosphate (FDP), a high energy intermediary metabolite of...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Gál J,Riedel BJ,Róth E,Bogár L,Tekeres M,Royston D

    更新日期:2000-09-10 00:00:00

  • [Intraoperative sonography to exclude thoracic injury].

    abstract::The authors present the case of a 29-year-old female with stab wound to the abdomen. After the initial fluid resuscitation and preliminary radiographic examinations immediate laparotomy was indicated due to hypovolaemic circulatory collapse. Splenectomy and gastric suture were necessary. Following the urgent intervent...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/OH.2007.28044

    authors: Baranyai Z,Jósa V,Jakab F,Szabó GJ

    更新日期:2007-08-12 00:00:00

  • [Examination of attitudes towards transplantation among patients with chronic renal failure].

    abstract::The patients' attitudes towards kidney transplantation are significantly affected by the acceptance of the treatment to have a better quality of life. Exploration of the cognitive-emotional relation in patients with chronic renal failure. Our study included 285 kidney patients. We investigated three groups of patients...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:10.1556/650.2018.31283

    authors: Illés A,Nemes B,Kovács S,Bugán A

    更新日期:2018-11-01 00:00:00

  • [The role of transesophageal echocardiography in the detection of coronary anomalies and anatomical variations].

    abstract:OBJECTIVES:The aim of the study is to examine the role of transesophageal echocardiography (TEE) in the diagnosis of anomalies and anatomic variations of the coronary arteries. BACKGROUND:In the past, coronary angiography was the only method for diagnostic confirmation in all cases with coronary anomalies, but even du...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Apró D,Lupkovics G,Mezey B

    更新日期:1998-09-13 00:00:00

  • [The effect of thrombocyte-derived growth factor on experimental inflammatory bowel disease].

    abstract::The role of Platelet-Derived Growth Factor (PDGF) was investigated in treatment of experimental inflammatory bowel disease (IBD) in animal models. A new model of IBD induced by the sulfhydryl (SH) alkylator iodoacetamide revealed that the most appropriate concentration of iodoacetamide is 6% given intracolonically onc...

    journal_title:Orvosi hetilap

    pub_type: 杂志文章

    doi:

    authors: Sándor Z,Kusstatscher S,Szeli D,Szabó S

    更新日期:1995-05-14 00:00:00