[The pathology of hepatitis C].

Abstract:

:The hepatitis C virus is an RNA virus, which belongs to the genus Hepaciviruses of the family Flaviviridae. Chronic hepatitis, cirrhosis, and ultimately even liver cancer may develop in over 80% of infected cases. The histological features of hepatitis C and hepatitis caused by other hepatotropic viruses show many similarities, however, certain specific histological characteristics are observable. Accordingly, intense lymphocytic infiltration around the periportal areas, steatosis and biliary alterations are frequent findings. Further characteristics of hepatitis C include liver cell destruction (apoptosis, necrosis), periportal inflammation and fibrosis, the degrees of which can be determined by means of the histology activity index. Our knowledge on the hepatitis C virus genome and the mechanism of replication of the virus have established the use of modern, direct-acting antivirals in the treatment of chronic hepatitis C.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Schaff Z,Gógl A,Dóra R,Halász T

doi

10.1556/650.2015.30178

subject

Has Abstract

pub_date

2015-05-24 00:00:00

pages

836-9

issue

21

eissn

0030-6002

issn

1788-6120

journal_volume

156

pub_type

杂志文章,评审
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    doi:

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  • [Transgastric gastro-jejunal anastomosis with flexible endoscope on a biosynthetic model].

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  • [Eosinophilic gastroenteritis].

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  • ["Folie a deux hallucinatoire"--a new case of induced hallucinatory psychosis. A new entity?].

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  • [Is non alcoholic steatohepatitis (NASH) part of the metabolic syndrome?].

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  • [Health related costs of smoking from the viewpoint of the Health Insurance Fund in Hungary].

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