Abstract:
BACKGROUND:In patients with colorectal cancer liver metastases (CRLM), right portal vein embolisation (RPVE) is used to increase the volume of the future remnant liver (FRL) before major hepatic resection. It is not established whether embolisation of segment 4 in addition RPVE (RPVE + 4) induces greater hypertrophy of the FRL. Limitations of prior studies include heterogenous populations and use of hypertrophy metrics sensitive to baseline variables. METHODS:From 2010 to 2015, consecutive patients undergoing RPVE or RPVE + 4 for CRLM, who had not undergone prior major hepatic resection and in whom imaging was available, were included in a retrospective study. Data were extracted from hospital electronic records. Volumetric assessments of segments 2-3 were made on cross-sectional imaging before and after embolisation and corrected for standardised liver volume. RESULTS:Ninety-nine patients underwent PVE, and 60 met the inclusion criteria. Thirty-eight patients underwent RPVE, and 22 underwent RPVE + 4. Forty-five patients had undergone median 6 cycles of prior chemotherapy. Eighteen patients had FRL metastases at PVE, and 16 had undergone subsegmental metastasectomy in the FRL. Assessments of the degree of hypertrophy (DH) of segments 2/3 were made at median 35 (interquartile range 30-49) days after PVE. RPVE + 4 resulted in a significantly greater increase in DH than RPVE (7.7 ± 1.8% vs 11.3 ± 2.6%, p = 0.011). No confounding association between baseline variables and the decision to undertake RPVE or RPVE + 4 was identified. Median survival was 2.4 years and was not influenced by segment 4 embolisation. CONCLUSION:RPVE + 4 results in greater DH of segments 2/3 than RPVE in people with CLRM.
journal_name
Cardiovasc Intervent Radioljournal_title
Cardiovascular and interventional radiologyauthors
Hammond CJ,Ali S,Haq H,Luo L,Wyatt JI,Toogood GJ,Lodge JPA,Patel JVdoi
10.1007/s00270-018-02159-5subject
Has Abstractpub_date
2019-04-01 00:00:00pages
552-559issue
4eissn
0174-1551issn
1432-086Xpii
10.1007/s00270-018-02159-5journal_volume
42pub_type
杂志文章abstract:PURPOSE:To assess the diagnostic accuracy of contrast-enhanced computed tomography (CT) for central pulmonary artery pathology in patients with cyanotic congenital heart disease (CCHD) and right ventricular outflow obstruction. METHODS:We compared contrast-enhanced CT and cine pulmonary arteriography in 24 patients in...
journal_title:Cardiovascular and interventional radiology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02563901
更新日期:1996-03-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02807353
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journal_title:Cardiovascular and interventional radiology
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更新日期:2002-09-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02552673
更新日期:1984-01-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s002700010110
更新日期:2000-11-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
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更新日期:1995-05-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
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更新日期:2000-11-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
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更新日期:2011-12-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章,评审
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更新日期:2015-06-01 00:00:00
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更新日期:2016-11-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
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更新日期:2020-11-01 00:00:00
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更新日期:2015-04-01 00:00:00
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更新日期:2009-09-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
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更新日期:2001-01-01 00:00:00
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更新日期:2001-05-01 00:00:00
abstract:PURPOSE:To evaluate the protective effect of using thermo-sensitive basement membrane extract (Matrigel) for hydrodissection to minimize thermal injury to nearby structures and to evaluate its heat sink effect on the ablation zone in radiofrequency ablation (RFA) of the liver. MATERIALS AND METHODS:First, the viscosit...
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更新日期:2017-07-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
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更新日期:1997-05-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
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更新日期:2004-09-01 00:00:00
abstract:PURPOSE:To retrospectively compare the postprocedure pain of hepatocellular carcinoma treated with irreversible electroporation (IRE) with radiofrequency ablation (RFA). METHODS:This Health Insurance Portability and Accountability Act-compliant, institutional review board-approved study compared postprocedure pain in ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-005-0080-6
更新日期:2006-03-01 00:00:00