Abstract:
:The purpose of this study was to assess the role of hepatic arterial embolization (HAE) and chemoembolization (HACE) in patients with large-volume liver metastases. Patients with metastatic neuroendocrine tumors, melanomas, or gastrointestinal stromal tumors (GISTs) with >75% liver involvement who underwent HAE or HACE were included in the study. Radiologic response, progression-free survival (PFS), overall survival (OS), and postprocedure complications were assessed. Sixty patients underwent 123 treatment sessions. Of the 48 patients for whom follow-up imaging was available, partial response was seen in 12 (25%) patients, minimal response in 6 (12%), stable disease in 22 (46%), and progressive disease in 8 (17%). Median OS and PFS were 9.3 and 4.9 months, respectively. Treatment resulted in radiologic response or disease stabilization in 82% and symptomatic response in 65% of patients with neuroendocrine tumors. Patients with neuroendocrine tumors had higher response rates (44% vs. 27% and 0%; p = 0.31) and longer PFS (9.2 vs. 2.0 and 2.3 months; p < 0.0001) and OS (17.9 vs. 2.4 and 2.3 months; p < 0.0001) compared to patients with melanomas and GISTs. Major complications occurred in 21 patients after 23 (19%) of the 123 sessions. Nine of the 12 patients who developed major complications resulting in death had additional risk factors--carcinoid heart disease, sepsis, rapidly worsening performance status, or anasarca. In conclusion, in patients with neuroendocrine tumors with >75% liver involvement, HAE/HACE resulted in symptom palliation and radiologic response or disease stabilization in the majority of patients. Patients with hepatic metastases from melanomas and GISTs, however, did not show any appreciable benefit from this procedure. Patients with massive liver tumor burden, who have additional risk factors, should not be subjected to HAE/HACE because of the high risk of procedure-related mortality.
journal_name
Cardiovasc Intervent Radioljournal_title
Cardiovascular and interventional radiologyauthors
Kamat PP,Gupta S,Ensor JE,Murthy R,Ahrar K,Madoff DC,Wallace MJ,Hicks MEdoi
10.1007/s00270-007-9186-3subject
Has Abstractpub_date
2008-03-01 00:00:00pages
299-307issue
2eissn
0174-1551issn
1432-086Xjournal_volume
31pub_type
杂志文章abstract::Cystic insulinomas are rare, with only three cases having been reported in the literature. It is not difficult to determine the site of such neoplasms, as cystic insulinomas are usually 4-10 cm in diameter. We report a patient with a histologically confirmed cystic insulinoma. This case is unique because of the small ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02743540
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:This study evaluated the survival benefit of a combination therapy with radiofrequency ablation (RFA) and intratumoral cisplatin (ITC) administration for lung tumors by using a rabbit VX2 tumor model. MATERIALS AND METHODS:Experiments were approved by the institutional animal care committee. VX2 tumor suspensi...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-020-02686-0
更新日期:2020-11-09 00:00:00
abstract::The aim of the present study was to determine whether there is a linear relation between the doses measured above and those measured under the lead apron of the radiologists performing interventional procedures. To monitor radiation exposure the International Commission of Radiological Protection (ICRP) recommends the...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-008-9307-7
更新日期:2008-05-01 00:00:00
abstract::The contrast left ventriculogram is the gold standard against which all other cardiac imaging techniques are measured. In the past decade, noninvasive methods such as radionuclide angiography, echocardiography, computed tomography (CT), and digital substraction imaging have become available. This review examines the r...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02552300
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Percutaneous vertebroplasty has been a good option to treat vertebral metastases. The pelvic bone is a common site of spread for many cancers. Using follow-up data for 126 patients, we evaluated the safety and efficacy of percutaneous osteoplasty (POP) to treat pelvic bone metastases. MATERIALS AND METHODS:...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-019-02320-8
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Comparison of the biocompatibility of self-expanding polyethylene terephthalate (PET) stents with self-expanding metallic stents (Wallstents). METHODS:Diameter- and length-matched PET stents and Wallstents were symmetrically implanted in the paired iliac arteries of 13 crossbred domestic swine. Stent deploymen...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577615
更新日期:1996-05-01 00:00:00
abstract::The authors report a case of Budd-Chiari syndrome treated by percutaneous transluminal angioplasty (PTA). In this case, the occlusion of three major hepatic veins with a big collateral to the inferior vena cava via the right inferior hepatic vein (RIHV) and stenosis of the ostium of RIHV were seen. We performed succes...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577938
更新日期:1986-01-01 00:00:00
abstract::The purpose of this investigation was to determine if addition of infragenicular steady-state (SS) magnetic resonance angiography (MRA) to first-pass imaging improves diagnostic performance compared with first-pass imaging alone in patients with peripheral arterial disease (PAD) undergoing whole-body (WB) MRA. Twenty ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-009-9759-4
更新日期:2010-06-01 00:00:00
abstract::Anatomic variations in the major arteries of the upper extremities have been reported in 11-24.4% of individuals. In a review of 100 upper extremity arteriograms, we found an overall incidence of 9%. High origin of the radial artery from the brachial artery was the most frequently encountered anomaly occurring in 7% o...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577379
更新日期:1989-05-01 00:00:00
abstract::The purpose of this paper is to describe a unique "eighth note" deformity of the autogenous radiocephalic fistula for hemodialysis and to retrospectively evaluate the efficacy and safety of its endovascular treatment. Over 3 years, a total of 808 patients and 558 autogenous radiocephalic fistulas were treated for vasc...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-009-9639-y
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION:The drop-off risk for patients awaiting liver transplantation for hepatocellular carcinoma (HCC) is 22%. Transplant liver availability is expected to worsen, resulting in longer waiting times and increased drop-off rates. Our aim was to determine whether chemoembolization can decrease this risk. PATIENTS ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-010-0077-7
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND/AIMS:Renal denervation (RDN) emerged as a treatment option for reducing blood pressure (BP) in patients with treatment-resistant hypertension (TRH). However, concerns have been raised regarding the incidence of late renal artery stenosis or thromboembolism after RDN. The goal of the current study was, theref...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-015-1192-2
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:Morton's neuroma (MN) is a leading cause of disability. The purpose of this study was to investigate the effectiveness of radiofrequency (RF) in patients with chronic pain refractory to conservative therapies. METHODS:Between September 2012 and December 2016, RF was performed on 52 patients. A sterile RF needl...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-017-1786-y
更新日期:2018-01-01 00:00:00
abstract::Magnetic resonance angiography (MRA) places high demands on instrumentation capabilities. Magnetic gradient strength capabilities, main magnetic field strength and homogeneity, and eddy current compensation all play a role in determining the quality of the flow studies. In addition, radiofrequency coil design and use ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02733895
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:The objective was to evaluate the local treatment efficacy of transarterial ethanol ablation (TEA) as compared to radiofrequency ablation (RFA) for small hepatocellular carcinoma (HCC). MATERIALS AND METHODS:This was a retrospective study between January 2005 and April 2017, in which the treatment outcomes of ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-020-02426-4
更新日期:2020-05-01 00:00:00
abstract::Radionuclide studies were sued in three patients to evaluate renal perfusion and function within 24 hours following transluminal dilatation. In one patient, technetium-99 m pertechnetate showed good renal perfusion one and 12 hours after a post-dilatation arteriogram had shown a renal artery intimal defect. Improved c...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02552420
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:To evaluate the effects of neoadjuvant intra-arterial chemotherapy (NAIC) for locally advanced uterine cervical cancer, and to analyze factors influencing the response to the chemotherapy. METHODS:Thirty-four patients with invasive cervical cancer more than 4 cm in diameter were enrolled in this study. NAIC wa...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-003-0506-y
更新日期:2003-05-01 00:00:00
abstract::Balloon-occluded retrograde transvenous obliteration (BRTO) of gastric varices is an image-guided transcatheter procedure used to treat gastric varices with sclerosants rather than decompression of the portal venous system. The history of its development, relevant portal venous, and systemic venous anatomic considerat...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章,评审
doi:10.1007/s00270-013-0715-y
更新日期:2014-04-01 00:00:00
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journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-001-0110-y
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:To determine the radiation dose associated with CT-guided percutaneous liver ablations and identify potential risk factors that result in higher radiation doses. MATERIALS AND METHODS:Between June 2011 and June 2015, 245 consecutive patients underwent 304 CT-guided liver ablation treatments. Patient demographi...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-018-2066-1
更新日期:2018-12-01 00:00:00
abstract::Modern advances in interventional radiology and nuclear medicine may now allow for safe and effective 90Y radioembolization to sites other than the liver. A general theory of predictive dosimetry based on the MIRD schema is proposed, adapted from the original partition model for liver 90Y radioembolization. ...
journal_title:Cardiovascular and interventional radiology
pub_type: 评论,信件
doi:10.1007/s00270-013-0783-z
更新日期:2014-08-01 00:00:00
abstract::In 19 out of 28 cases of single ventricle with inverted infundibulum and 1-transposition of the great arteries the right coronary artery arose from the posterior aortic sinus, the right anterior aortic sinus being the noncoronary one. This coronary arterial pattern was described before only in association with d-trans...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02552415
更新日期:1981-01-01 00:00:00
abstract::The results of the first 100 patients to receive Gianturco-Rösch "Z" stents is presented along with recommendations for their use. The patient population was comprised of 57 men and 43 women, age range 17-85 years (mean 65 years). Fifty-four of the patients had benign obstruction and 46 had malignant obstruction. Of t...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02734120
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:This study was designed to evaluate preliminarily the feasibility and safety of magnetic resonance-guided focused ultrasound (MRgFUS) for treatment of solid tumors in the upper abdomen. METHODS:We enrolled one patient with hepatocellular carcinoma and two patients with pancreatic adenocarcinoma for MRgFUS abla...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-014-0861-x
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:The purpose of our study was to evaluate the diagnostic accuracy of MRI-guided percutaneous transthoracic needle biopsy (PTNB) of solitary pulmonary nodules (SPNs). METHODS:Retrospective review of 69 patients who underwent MR-guided PTNB of SPNs was performed. Each case was reviewed for complications. The fi...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-014-0915-0
更新日期:2015-04-01 00:00:00
abstract::A technique is described that allowed percutaneous retrieval of an endoscopically placed, obstructed biliary stent using loop snare capture of an angled hydrophilic wire which was wrapped around the stent initially. ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577656
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:Transradial access (TRA) has shown lower morbidity and decreased bleeding complications compared to transfemoral access. This study evaluates the safety and feasibility of TRA in thrombocytopenic patients undergoing visceral interventions. METHODS AND MATERIALS:Patients who underwent visceral interventions via...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-015-1264-3
更新日期:2016-05-01 00:00:00
abstract::Rectal injuries caused by foreign bodies or iatrogenic insertions may lead to severe complications whose therapeutic management remains controversial. At times, both the rapid identification and treatment of subsequent active rectal bleeding may be challenging, especially when endoscopy fails to locate and control the...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-004-0168-4
更新日期:2005-07-01 00:00:00
abstract::We report on a 72-year-old female with an unusual intracranial bleeding complication after an extracranial carotid artery stenting procedure performed for a tight left ICA stenosis associated with contralateral carotid occlusion. Two hours after the procedure, the initial signs of intracranial bleeding appeared that l...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-004-0155-9
更新日期:2005-07-01 00:00:00
abstract::Iatrogenic cardiac perforation is a recognized complication of central venous catheterization. We report a fatal complication by a 10F introducer sheath which was left in place and resulted in perforation of the right atrial wall 8 h later. This case is reported to emphasize the increased risk of cardiac perforation f...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02602990
更新日期:1993-03-01 00:00:00