Vitamin C influence on localized adjuvant arthritis.

Abstract:

:This work attempts to determine the influence of vitamin C on locally induced inflammation and arthritis in rat paws, as measured by rat paw swelling, polymorphonuclear leukocyte infiltration, pain, and surface skin temperature. Daily subcutaneous administration of 150 mg/kg of vitamin C over 20 days reduced arthritic swelling, increased pain tolerance, and decreased polymorphonuclear leukocyte infiltration, with no significant change in surface temperature. Vitamin C may provide podiatrists with a supplemental or alternative treatment for patients with rheumatoid arthritis.

journal_name

J Am Podiatr Med Assoc

authors

Davis RH,Rosenthal KY,Cesario LR,Rouw GR

doi

10.7547/87507315-80-8-414

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

414-8

issue

8

eissn

8750-7315

issn

1930-8264

journal_volume

80

pub_type

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