LncRNA ZNF667-AS1 inhibits inflammatory response and promotes recovery of spinal cord injury via suppressing JAK-STAT pathway.

abstract：OBJECTIVE:The Nuss procedure is a minimally invasive approach used to treat the pectus excavatum. One to three curved metal bars are inserted behind the sternum in order to push it into a normal position. A bilateral thoracoscopy, with 3 or 4 incisions on each side, has been reported as a safe method to repair the ches...

journal_title：European review for medical and pharmacological sciences

authors： Cafarotti S,Memoli E,Patella M,Rugel G,Minerva EM,Mendoza CM,Tessitore A,Hamitaga F

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To investigate the correlations of serum vascular endothelial growth factor (VEGF) and matrix metalloproteinase-2 (MMP-2) levels with colorectal liver metastasis (CLM) in patients with colorectal cancer (CRC), and determine the effects of transhepatic arterial chemoembolization (TACE) on their expressions. P...

journal_title：European review for medical and pharmacological sciences

authors： Xu H,Ren YJ,Liu K,Min XL,Yang L,Zhou Y,Zheng J,Yang C

更新日期：2018-06-01 00:00:00

abstract：:Novel coronavirus disease-19 (COVID-19) has widely spread all over the world and seriously threatened people's health. This disease is currently diagnosed by clinical features, chest computed tomography (CT) scan, and nucleic acid test of severe acute respiratory syndrome coronavirus (SARS-CoV-2). Recently, some studi...

journal_title：European review for medical and pharmacological sciences

authors： Qian WJ,Li L,Sun LY,Shi HR,Liu H,Jing X

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:It is well documented that oxidative stress is a basic mechanism behind the development of diabetic state. The current study was undertaken to elucidate the hypoglycemic role of zinc, selenium and vitamin E and their mixture in comparison with the antidiabetic drug glibenclamide. MATERIALS AND METHODS:Male W...

journal_title：European review for medical and pharmacological sciences

authors： Aly HF,Mantawy MM

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To observe the effect of metformin on the tight junction of intestinal epithelial cells and its relevant mechanism. MATERIALS AND METHODS:Caco-2 cell monolayers were incubated with or without tumor necrosis factor-α (TNF-α) (10 ng/mL) in the absence or presence of indicated concentrations of metformin. Trans...

journal_title：European review for medical and pharmacological sciences

authors： Zhou HY,Zhu H,Yao XM,Qian JP,Yang J,Pan XD,Chen XD

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Most ulcers occur with slough and need debridement treatment. Surgical treatment is usually performed but many patients need an additional chemical therapy to promote healing process. This type of wound bed preparation is slower than surgical one, but it is essential in those patients who are not eligible fo...

journal_title：European review for medical and pharmacological sciences

authors： Onesti MG,Fioramonti P,Carella S,Fino P,Sorvillo V,Scuderi N

更新日期：2013-01-01 00:00:00

abstract：:The neurogenic dysfunctions of the detrusor and the sphincter are caused by either a known congenital defect of the nervous system or by acquired damage to the nervous system. In patients with idiopathic bladder dysfunctions neurological examinations fail to reveal any pathology in the nervous system. The treatment st...

journal_title：European review for medical and pharmacological sciences

authors： Kroll P,Zachwieja J

更新日期：2016-04-01 00:00:00

abstract：AIM OF STUDY:To evaluate the prevalence of latex allergy in a population of children with spina bifida (SB) and to assess the role of early exposure to latex products and others risk factors. INTRODUCTION:SB is related with an higher incidence of latex allergic reactions. These patients received repeated surgical proc...

journal_title：European review for medical and pharmacological sciences

authors： Ausili E,Tabacco F,Focarelli B,Nucera E,Patriarca G,Rendeli C

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Vaginal atrophy is a chronic, progressive medical condition that affects fifty percent of postmenopausal women, causing symptoms like dyspareunia, vaginal dryness, and vaginal irritation. Until recently, the only prescription options were systemic and vaginal estrogen therapies that might be limited by concer...

journal_title：European review for medical and pharmacological sciences

authors： Del Pup L

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:In this study, we investigated whether certain types of lipid profiles are major contributors of acute ischemic stroke (AIS). PATIENTS AND METHODS:We screened 13,285 hospitalized patients in two stroke medical centers treated with thrombolysis, thrombectomy, or conventional care for anterior cerebral artery-...

journal_title：European review for medical and pharmacological sciences

authors： Niu L,Jiang SW,Wang Y,Peng Y,Fei AH,Wang HR,Li Y,Zhang JC,Meaney C,Gao CJ,Pan SM

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:GSK-3β negatively regulates Wnt/β-catenin signaling pathway. The abnormal miR-155 expression is associated with bladder cancer. Bioinformatics analysis revealed a complementary binding site between miR-155 and GSK-3β mRNA. This study investigated the role of miR-155 in the proliferation and apoptosis of bladd...

journal_title：European review for medical and pharmacological sciences

authors： Dong ZC,Zhang D,Zhang XX,Yao ZQ,Wu H,Chen CH,Tian JQ

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:We investigated whether DHEA supplementation had an impact on ovarian reserve parameters and pregnancy rates in patients with poor ovarian response (POR) and primary ovarian insufficiency (POI). PATIENTS AND METHODS:A total of 34 people, 6 patients with POI and 28 patients with POR, were included in the stud...

journal_title：European review for medical and pharmacological sciences

authors： Ozcil MD

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the level of circ-0003998 in osteosarcoma tissues and cell lines, and to analyze its relation with prognosis of patients, as well as its effect on biological behaviors of osteosarcoma cells. In addition, the potential mechanism of circ-0003998 in promoting osteosarcoma...

journal_title：European review for medical and pharmacological sciences

authors： Wang L,Du ZG,Huang H,Li FS,Li GS,Xu SN

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:In this study, we investigated the regulation of resveratrol (RV) on miR-34a alteration due to ARI and further studied the involvement of miR-34a/Sirt1 signaling pathway in ROS generation and cell survival after ARI. MATERIALS AND METHODS:In-vitro anoxia and reoxygenation injury (ARI) model based on rat hear...

journal_title：European review for medical and pharmacological sciences

authors： Yang B,Ma S,Wang YB,Xu B,Zhao H,He YY,Li CW,Zhang J,Cao YK,Feng QZ

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:p38 mitogen-activated protein kinase (p38MAPK) is a critical negative regulator for nucleus pulposus (NP) cell metabolism contributing to intervertebral disc degeneration (IDD). Histone deacetylase 4 (HDAC4) has the ability to mediate cell proliferation and is affected by p38MAPK. It is unclear whether the p3...

journal_title：European review for medical and pharmacological sciences

authors： Wu YD,Guo ZG,Deng WJ,Wang JG

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Currently, detection of SARS-CoV-2 RNA is standard in the diagnosis of COVID-19 (2019-nCoV). However, reliable and rapid serological diagnostic methods to screen SARS-CoV-2 infected patients, including those who do not have overt symptoms, are urgently needed. Most studies have described serological tests bas...

journal_title：European review for medical and pharmacological sciences

authors： Guo CC,Mi JQ,Nie H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Turner syndrome is the most common genetic disorder in females. In most subjects, with a normal physical appearance at birth, the diagnosis is suspected long after birth because of short stature, delayed puberty, primary or secondary amenorrhea or infertility. Abnormalities of liver function tests are report...

journal_title：European review for medical and pharmacological sciences

authors： Valentini P,Angelone DF,Rossodivita A,Francalanci P,Buonsenso D,Ceccarelli M,Callea F

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To determine the expression of neutrophil gelatinase-associated lipocalin (NGAL) and vascular endothelial growth factor (VEGF) in endometrial carcinoma. PATIENTS AND METHODS:The clinical features (FIGO staging, pathological type, differentiation level, myometrial invasion depth and tumor size) and immunostai...

journal_title：European review for medical and pharmacological sciences

authors： Xu H,Sun X,Sun WJ

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Frontal recess is the anatomical region most difficult to manage in endoscopic frontal sinus surgery due to the extreme variability of the cell patterns that may be observed in this area. CT has always been the gold standard in preoperative evaluation, but especially in the assessment of the causes of fronta...

journal_title：European review for medical and pharmacological sciences

authors： Minni A,Messineo D,Attanasio G,Pianura E,D'Ambrosio F

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To observe the effect of micro ribonucleic acid (miR)-9 on the myocardial fibrosis (MF) in rats and explore its mechanism of action. MATERIALS AND METHODS:A total of 30 rats were selected to prepare the models of MF and randomly divided into Sham group, Model group and MiR-9 group. The rat heart weight (HW)/...

journal_title：European review for medical and pharmacological sciences

authors： Jin X,Yu LL,Yu CX

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Determination of the active fraction and compounds of the dichloromethanol extract of Schinus molle seeds and evaluation of their biological effects. MATERIALS AND METHODS:Dried seeds of Schinus molle were sequentially extracted in hexane, acetyl acetate and dichloromethane. The dichloromethane extract was s...

journal_title：European review for medical and pharmacological sciences

authors： Taylor A,Oyedeji OO,Aremu O,Oyemitan I,Gwebu ET,Oyedeji AO,Nkeh-Chungag BN

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of miR-519d on the 5-fluorouracil resistance in colorectal cancer cells and to explore the mechanism. MATERIALS AND METHODS:Colorectal cancer cells HCT116 and SW480 were transfected with miR519d-mimic or siCCND1 by transient transfection. The sensitivity of cells to 5-Fu was assaye...

journal_title：European review for medical and pharmacological sciences

authors： Huang R,Lin JY,Chi YJ

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Perlecan, which is also called heparan sulfate proteoglycan 2 (HSPG2), is a protein encoded by the HSPG2 gene that maps to 1p36.12 in the human genome. In this study, we assessed the independent prognostic value of HSPG2 in terms of overall survival (OS) and recurrence-free survival (RFS) in patients with LGG...

journal_title：European review for medical and pharmacological sciences

authors： Ma XL,Shang F,Ni W,Zhu J,Luo B,Zhang YQ

更新日期：2018-10-01 00:00:00

abstract：UNLABELLED:BACKGROUND, OBJECTIVES: Pancreatic cancer ranks fourth for cancer mortality for men and women in the United States. This is a particularly devastating cancer since the case-fatality proportion approaches 90% within 12 months following diagnosis. Therefore, understanding the etiology and identifying the risk ...

journal_title：European review for medical and pharmacological sciences

authors： Cappellani A,Cavallaro A,Di Vita M,Zanghi A,Piccolo G,Lo Menzo E,Cavallaro V,Malaguarnera M,Giaquinta A,Veroux M,Cimino L,Berretta M

更新日期：2012-02-01 00:00:00

abstract：:Cryptorchidism is the most frequent defect of the male urogenital tract at birth. It represents a risk factor for primitive testiculopathy associated with long-term complications (infertility, testicular neoplasia, and hormonal changes). An only consensus exists: "children with bilateral cryptorchidism who are not tre...

journal_title：European review for medical and pharmacological sciences

authors： La Vignera S,Calogero AE,Condorelli R,Marziani A,Cannizzaro MA,Lanzafame F,Vicari E

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the expression profile and the underlying mechanism of the long intergenic non-protein coding RNA AL161431.1 in EC (endometrial carcinoma). MATERIALS AND METHODS:In this study, the expression data for the lncRNA AL161431.1 in EC was downloaded from The Cancer Genome Atl...

journal_title：European review for medical and pharmacological sciences

authors： Gu ZR,Liu W

更新日期：2020-03-01 00:00:00

abstract：:This short review describes the conceptual development in the search for the enteric neural circuits with the initial identifications of the classes of enteric neurons on the bases of their morphology, neurochemistry, biophysical properties, projections and connectivity. The discovery of the presence of multiple neuro...

journal_title：European review for medical and pharmacological sciences

authors： Costa M,Brookes SH

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the influence of long non-coding ribonucleic acid (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) on neuronal apoptosis in rats with cerebral infarction (CI), and to further explore the underlying mechanism of lncRNA ANRIL in the occurrence and development of ...

journal_title：European review for medical and pharmacological sciences

authors： Zhao JH,Wang B,Wang XH,Wang JR,Xu CW

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Familial hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease. While sarcomeric gene mutations explain many HCM cases, the genetic basis of about half of HCM cases remains elusive. Here we aimed to identify the gene causing HCM in a non-consanguineous Saudi Arabian family with affected...

journal_title：European review for medical and pharmacological sciences

authors： Carlus SJ,Almuzaini IS,Karthikeyan M,Loganathan L,Al-Harbi GS,Carlus FH,Al-Mazroea AH,Morsy MM,Abo-Haded HM,Abdallah AM,Al-Harbi KM

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To investigate the relationships between blood uric acid (BUA) level and the incidence, progression and deterioration of diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS:A total of fifty patients with T2DM alone whose glycosylated hemoglobin (HbA1c) were under ...

journal_title：European review for medical and pharmacological sciences

authors： Li GX,Jiao XH,Cheng XB

更新日期：2018-01-01 00:00:00