A single-parameter logistic equation for fitting concentration-response curves from standard acute ecotoxicity assays.

Abstract:

:A set of 69 concentration-response curves from 5 acute ecotoxicity assays was fitted with a 2-parameter logistic equation. High correlation between values of regression parameters suggested similar slopes of the curves. This enabled derivation of the empirical single-parameter logistic equation with the sole median effective concentration (EC50) parameter. Such an equation might be useful in the evaluation of lower-quality (preliminary) experimental data and for the reduction of the number of test organisms and of testing costs.

journal_name

Environ Toxicol Chem

authors

Trögl J,Benediktová K,Pilařová V,Synek V

doi

10.1002/etc.2328

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

2412-6

issue

10

eissn

0730-7268

issn

1552-8618

journal_volume

32

pub_type

杂志文章
  • Heavy metal content in liver and kidneys of grey seals (Halichoerus grypus) in various life stages correlated with metallothionein levels: Some metal-binding characteristics of this protein.

    abstract::Liver and kidneys from grey seals (Halichoerus grypus) in their natural habitats in Norwegian waters contain high levels of Cd and Hg as well as metallothionein (MT). The data show significant placental transfer of heavy metals in seals. The MT concentrations were higher in fetus liver and kidneys than in the liver an...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.5620181034

    authors: Teigen SW,Andersen RA,Daae HL,Skaare JU

    更新日期:1999-10-01 00:00:00

  • Periphyton uptake and trophic transfer of coal fly-ash-derived trace elements.

    abstract::To determine whether the bioavailability of trace elements derived from coal ash leachates varies with the geochemical conditions associated with their formation, we quantified periphyton bioaccumulation and subsequent trophic transfer to the mayfly Neocloeon triangulifer. Oxic ash incubations favored periphyton uptak...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3864

    authors: Scheibener SA,Rivera NA,Hesterberg D,Duckworth OW,Buchwalter DB

    更新日期:2017-11-01 00:00:00

  • Anaerobic transformation of compounds of technical toxaphene. 2. Fate of compounds lacking geminal chlorine atoms.

    abstract::The major toxaphene metabolites in sediment and soils (2-exo,3-endo,6-exo,8,9,10-hexachlorobornane [B6-923] and 2-endo,3-exo,5-endo,6-exo,8,9,10-heptachlorobornane [B7-1001]) were incubated with the isolated gram-negative bacterium Dehalospirillum multivorans. Within 14 d, biotransformation of B7-1001 was nearly quant...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/03-221

    authors: Ruppe S,Neumann A,Braekevelt E,Tomy GT,Stern GA,Maruya KA,Vetter W

    更新日期:2004-03-01 00:00:00

  • Polychlorinated biphenyl profiles in ringed seals (Pusa Hispida) reveal historical contamination by a military radar station in Labrador, Canada.

    abstract::Significant amounts of soil contaminated with polychlorinated biphenyls (PCBs) were discovered at a military radar station in Saglek Bay, Labrador, Canada, in 1996. Subsequent work showed elevated PCB concentrations in local marine sediments, in the benthic-associated food web, and in some ringed seals (Pusa hispida)....

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2468

    authors: Brown TM,Fisk AT,Helbing CC,Reimer KJ

    更新日期:2014-03-01 00:00:00

  • Analysis of arsenic bioavailability in contaminated soils.

    abstract::The bioavailable arsenic (As) content of contaminated soils was determined by joint analyses of acid-soluble, total water-soluble, and biovailable As by using a luminescent bacterial sensor, Escherichia coli MC1061(pTOO31). According to the results of this study, a significant positive correlation was found between th...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Turpeinen R,Virta M,Häggblom MM

    更新日期:2003-01-01 00:00:00

  • Assessment of potential immunotoxic effects caused by cypermethrin, fluoxetine, and thiabendazole using heat shock protein 70 and interleukin-1β mRNA expression in the anuran Xenopus laevis.

    abstract::The current study describes the effect of cypermethrin, fluoxetine, and thiabendazole, at environmentally relevant concentrations, on the expression of heat shock protein 70 (HSP70) and interleukin 1β (IL-1β), using Xenopus laevis larvae as animal model. Cytokines and interleukins are considered good predictors of the...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.313

    authors: Martini F,Fernández C,Segundo LS,Tarazona JV,Pablos MV

    更新日期:2010-11-01 00:00:00

  • The further development of ionoregulatory measures as biomarkers of sensitivity and effect in fish species.

    abstract::Extensive season-by-season sampling was used to establish the normal range of whole-body Na+ and Cl- and Na+ uptake in healthy populations of two fish species, rainbow trout, Oncorhynchus mykiss, and fathead minnow, Pimephales promelas, of known differences in sensitivity to ionoregulatory toxicants (low pH, trace met...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Croke SJ,McDonald DG

    更新日期:2002-08-01 00:00:00

  • Dissipation of double-stranded RNA in aquatic microcosms.

    abstract::Silencing genes of a pest with double-stranded RNA (dsRNA) is a promising new pest management technology. As part of the environmental risk assessment for dsRNA-based products, the environmental fate and the potential for adverse effects to on-target organisms should be characterized. In the present study, a nonbioact...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3648

    authors: Albright VC 3rd,Wong CR,Hellmich RL,Coats JR

    更新日期:2017-05-01 00:00:00

  • Bioluminescence inhibition assays for toxicity screening of wood extractives and biocides in paper mill process waters.

    abstract::The risk associated with wood extractives, biocides, and other additives in pulp and paper mill effluents was evaluated by performing a characterization of process waters and effluents in terms of toxicity and chemical analysis. The individual toxicity of 10 resin acids, two unsaturated fatty acids, and three biocides...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/02-632

    authors: Rigol A,Latorre A,Lacorte S,Barceló D

    更新日期:2004-02-01 00:00:00

  • Combined effects of temperature and pyriproxyfen stress in a full life-cycle test with Chironomus riparius (Insecta).

    abstract::Traditional risk assessment guidelines employ acute or chronic toxicity tests for a maximum of one generation of organisms. These tests are usually performed in the laboratory at a constant standard temperature, although in the field organisms may experience different temperatures, which may be a source of additional ...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.1969

    authors: Tassou KT,Schulz R

    更新日期:2012-10-01 00:00:00

  • Environmental fractionation of PCBs and PBDEs during particle transport as recorded by sediments in coastal waters.

    abstract::The Strait of Georgia (British Columbia, Canada) is a hydrologically complex inland sea with a rich abundance and diversity of species of aquatic life. Marine sediments, as both a sink for hydrophobic contaminants and a potential source for aquatic food webs, were collected from 41 sites throughout the 6,900-km(2) Str...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.542

    authors: Grant PB,Johannessen SC,Macdonald RW,Yunker MB,Sanborn M,Dangerfield N,Wright C,Ross PS

    更新日期:2011-07-01 00:00:00

  • Comparison of the cytotoxic impact of chlorfluazuron on selected insect and human cell lines.

    abstract::To gain new insight into the mechanism of selective cytotoxicity of benzoylureas as insecticides, the in vitro mode of action of chlorfluazuron was investigated on lepidopteran Tn5B1-4 and Sf-21 cells and human Hek293 and HepG2 cells. Chlorfluazuron inhibited the proliferation of Tn5B1-4 and Sf-21 cells with 50% inhib...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2969

    authors: Huang Q,Wu X,Yu X,Zhang L,Lu M,Tao L

    更新日期:2015-07-01 00:00:00

  • Multigenerational acclimation of Daphnia magna to mercury: relationships between biokinetics and toxicity.

    abstract::We examined the effects of multigenerational exposure of mercury (Hg) on Hg toxicity and biokinetics in a population of Daphnia magna. After chronic Hg exposure at 3.8 microg Hg/L, the first generation (F0) adults had an elevated 24-h median lethal concentration (LC50) of Hg (76 microg/L) when compared to the control ...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/05-085r.1

    authors: Tsui MT,Wang WX

    更新日期:2005-11-01 00:00:00

  • Implications of global climate change for the assessment and management of human health risks of chemicals in the natural environment.

    abstract::Global climate change (GCC) is likely to alter the degree of human exposure to pollutants and the response of human populations to these exposures, meaning that risks of pollutants could change in the future. The present study, therefore, explores how GCC might affect the different steps in the pathway from a chemical...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2046

    authors: Balbus JM,Boxall AB,Fenske RA,McKone TE,Zeise L

    更新日期:2013-01-01 00:00:00

  • Chronic toxicity of binary-metal mixtures of cadmium and zinc to Daphnia magna.

    abstract::The present study characterized the chronic effect of binary-metal mixtures of cadmium (Cd) and zinc (Zn) on Daphnia magna. The titration design was chosen to characterize the 21-d chronic effects of the binary-metal mixtures on survival, growth, reproduction, and metal accumulation in D. magna. Using this design, inc...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3830

    authors: Pérez E,Hoang TC

    更新日期:2017-10-01 00:00:00

  • PCB concentrations in shrimp from major import markets and the United States.

    abstract::Currently, environmental studies describing levels of polychlorinated biphenyls (PCBs) in imported shrimp are limited, particularly studies of aquaculture shrimp. In the present study, we measured concentrations of the 209 PCB congeners in 84 uncooked, warm-water shrimp samples from the United States and 14 other coun...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.1803

    authors: Fillos D,Scott LL,De Sylor MA,Grespin M,Luksemburg WJ,Finley B

    更新日期:2012-05-01 00:00:00

  • Toxicant- and response-specific comparisons of statistical methods for estimating effective concentrations.

    abstract::Standard U.S. Environmental Protection Agency (U.S. EPA) statistical analyses of whole effluent toxicity tests involve the estimation of the concentration associated with a specified level of inhibition relative to control responses. Current U.S. EPA estimation methods (linear interpolation or probit-based methods) ar...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Hughes MR,Bailer AJ,Denton DL

    更新日期:2001-06-01 00:00:00

  • Availability of metals to the nematode Caenorhabditis elegans: toxicity based on total concentrations in soil and extracted fractions.

    abstract::Current regulation of metals in soils is based on total metal concentrations rather than on actual exposure concentrations. Considering the extreme variation in soil physicochemical properties, total concentrations are not reflective of the availability and resultant toxicity of metals in different soils. In this stud...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Boyd WA,Williams PL

    更新日期:2003-05-01 00:00:00

  • Occurrence and distribution pattern of acidic pharmaceuticals in surface water, wastewater, and sediment of the Msunduzi River, Kwazulu-Natal, South Africa.

    abstract::The paucity of information on the occurrence of pharmaceuticals in the environment in African countries led the authors to investigate 8 acidic pharmaceuticals (4 antipyretics, 3 antibiotics, and 1 lipid regulator) in wastewater, surface water, and sediments from the Msunduzi River in the province of KwaZulu-Natal, So...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3144

    authors: Agunbiade FO,Moodley B

    更新日期:2016-01-01 00:00:00

  • Toward improved analysis of concentration data: Embracing nondetects.

    abstract::Various statistical tests on concentration data serve to support decision-making regarding characterization and monitoring of contaminated media, assessing exposure to a chemical, and quantifying the associated risks. However, the routine statistical protocols cannot be directly applied because of challenges arising f...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章,评审

    doi:10.1002/etc.4046

    authors: Shoari N,Dubé JS

    更新日期:2018-03-01 00:00:00

  • Equilibrium modeling: a pathway to understanding observed perfluorocarboxylic and perfluorosulfonic acid behavior.

    abstract::Equilibrium distribution models of hydrophobic neutral partitioning of the perfluorinated carboxylic and sulfonic acids were shown, without the need for any physical chemical properties, to successfully predict the sediment-water distribution (D(SW) ) directly from independently measured equilibrium tissue distributio...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.637

    authors: Webster EM,Ellis DA

    更新日期:2011-10-01 00:00:00

  • Acute sensitivity of a broad range of freshwater mussels to chemicals with different modes of toxic action.

    abstract::Freshwater mussels, one of the most imperiled groups of animals in the world, are generally underrepresented in toxicity databases used for the development of ambient water quality criteria and other environmental guidance values. Acute 96-h toxicity tests were conducted to evaluate the sensitivity of 5 species of juv...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3642

    authors: Wang N,Ivey CD,Ingersoll CG,Brumbaugh WG,Alvarez D,Hammer EJ,Bauer CR,Augspurger T,Raimondo S,Barnhart MC

    更新日期:2017-03-01 00:00:00

  • First-generation annotations for the fathead minnow (Pimephales promelas) genome.

    abstract::Ab initio gene prediction and evidence alignment were used to produce the first annotations for the fathead minnow (Pimephales promelas) genome. We also describe a genome browser, hosted by the Society of Environmental Toxicology and Chemistry, that provides simplified access to the annotation data in context with the...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3929

    authors: Saari TW,Schroeder AL,Ankley GT,Villeneuve DL

    更新日期:2017-12-01 00:00:00

  • Cumulative toxicity of neonicotinoid insecticide mixtures to Chironomus dilutus under acute exposure scenarios.

    abstract::Extensive agricultural use of neonicotinoid insecticide products has resulted in the presence of neonicotinoid mixtures in surface waters worldwide. Although many aquatic insect species are known to be sensitive to neonicotinoids, the impact of neonicotinoid mixtures is poorly understood. In the present study, the cum...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3878

    authors: Maloney EM,Morrissey CA,Headley JV,Peru KM,Liber K

    更新日期:2017-11-01 00:00:00

  • Degradation of a stilbene-type fluorescent whitening agent with hypochlorite: identification of the degradation products by capillary electrophoresis.

    abstract::The E,E-(4,4'-bis[2-sulfostyryl]biphenyl) (DSBP) is a fluorescent whitening agent widely used by the textile and detergent industries to whiten fabrics. Hypochlorite used to bleach fabrics oxidizes DSBP slowly at room temperature and in a higher rate at 60 degrees C. The ions of metals such as Fe, Cu, and Mn accelerat...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Blanco M,Jiménez L,Valverde I

    更新日期:2001-10-01 00:00:00

  • Insights into the development of fungal biomarkers for metal ecotoxicity assessment: case of Trametes versicolor exposed to copper.

    abstract::The relationship between the physiological state of fungi and the response of their functional system to metals is not known, limiting the use of fungal enzymes as tools for assessing metal ecotoxicity in terrestrial ecosystems. The present study attempts to establish how the development phases modulate the secretion ...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.101

    authors: Lebrun JD,Trinsoutrot-Gattin I,Laval K,Mougin C

    更新日期:2010-04-01 00:00:00

  • Survival and reproduction of enchytraeid worms, Oligochaeta, in different soil types amended with energetic cyclic nitramines.

    abstract::Hexanitrohexaazaisowurtzitane (CL-20), a new polycyclic polynitramine, has the same functional nitramine groups (N-NO2) as the widely used energetic chemicals hexahydro-1,3,5-trinitro-1,3,5-triazacyclohexane (royal demolition explosive [RDX]) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (high-melting explosive...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/054-188r.1

    authors: Dodard SG,Sunahara GI,Kuperman RG,Sarrazin M,Gong P,Ampleman G,Thiboutot S,Hawari J

    更新日期:2005-10-01 00:00:00

  • Validation of the target lipid model for toxicity assessment of residual petroleum constituents: monocyclic and polycyclic aromatic hydrocarbons.

    abstract::A method is presented for developing scientifically defensible, numeric guidelines for residual petroleum-related constituents, specifically monocyclic aromatic hydrocarbons (MAHs) and polycyclic aromatic hydrocarbons (PAHs), in the water column. The guidelines are equivalent to a HC5 (i.e., hazard concentration to 5%...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/08-271.1

    authors: McGrath JA,Di Toro DM

    更新日期:2009-06-01 00:00:00

  • Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium.

    abstract::DNA microarray technology enables genome-wide detection of cell response at the transcriptional level. We are planning to make bioassay systems that can detect environmental chemicals to screen for potential bioreactive agents. To develop a DNA microarray for our purposes, the changes in gene expression underlying the...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/1551-5028(2001)020<2353:bocuad>2.0.co;2

    authors: Momose Y,Iwahashi H

    更新日期:2001-10-01 00:00:00

  • Toxicity of aqueous fullerene in adult and larval Fundulus heteroclitus.

    abstract::Aqueous suspensions of fullerene aggregates (aqua-nC60) were used to investigate the movement of carbon-based nanomaterials in a marine water column and to determine their effects on different life stages of a marine teleost. Fullerene aggregates formed precipitates as a result of mixing in natural seawater, and level...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/07-632.1

    authors: Blickley TM,McClellan-Green P

    更新日期:2008-09-01 00:00:00