Abstract:
:A set of 69 concentration-response curves from 5 acute ecotoxicity assays was fitted with a 2-parameter logistic equation. High correlation between values of regression parameters suggested similar slopes of the curves. This enabled derivation of the empirical single-parameter logistic equation with the sole median effective concentration (EC50) parameter. Such an equation might be useful in the evaluation of lower-quality (preliminary) experimental data and for the reduction of the number of test organisms and of testing costs.
journal_name
Environ Toxicol Chemjournal_title
Environmental toxicology and chemistryauthors
Trögl J,Benediktová K,Pilařová V,Synek Vdoi
10.1002/etc.2328subject
Has Abstractpub_date
2013-10-01 00:00:00pages
2412-6issue
10eissn
0730-7268issn
1552-8618journal_volume
32pub_type
杂志文章abstract::Liver and kidneys from grey seals (Halichoerus grypus) in their natural habitats in Norwegian waters contain high levels of Cd and Hg as well as metallothionein (MT). The data show significant placental transfer of heavy metals in seals. The MT concentrations were higher in fetus liver and kidneys than in the liver an...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.5620181034
更新日期:1999-10-01 00:00:00
abstract::To determine whether the bioavailability of trace elements derived from coal ash leachates varies with the geochemical conditions associated with their formation, we quantified periphyton bioaccumulation and subsequent trophic transfer to the mayfly Neocloeon triangulifer. Oxic ash incubations favored periphyton uptak...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3864
更新日期:2017-11-01 00:00:00
abstract::The major toxaphene metabolites in sediment and soils (2-exo,3-endo,6-exo,8,9,10-hexachlorobornane [B6-923] and 2-endo,3-exo,5-endo,6-exo,8,9,10-heptachlorobornane [B7-1001]) were incubated with the isolated gram-negative bacterium Dehalospirillum multivorans. Within 14 d, biotransformation of B7-1001 was nearly quant...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/03-221
更新日期:2004-03-01 00:00:00
abstract::Significant amounts of soil contaminated with polychlorinated biphenyls (PCBs) were discovered at a military radar station in Saglek Bay, Labrador, Canada, in 1996. Subsequent work showed elevated PCB concentrations in local marine sediments, in the benthic-associated food web, and in some ringed seals (Pusa hispida)....
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2468
更新日期:2014-03-01 00:00:00
abstract::The bioavailable arsenic (As) content of contaminated soils was determined by joint analyses of acid-soluble, total water-soluble, and biovailable As by using a luminescent bacterial sensor, Escherichia coli MC1061(pTOO31). According to the results of this study, a significant positive correlation was found between th...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::The current study describes the effect of cypermethrin, fluoxetine, and thiabendazole, at environmentally relevant concentrations, on the expression of heat shock protein 70 (HSP70) and interleukin 1β (IL-1β), using Xenopus laevis larvae as animal model. Cytokines and interleukins are considered good predictors of the...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.313
更新日期:2010-11-01 00:00:00
abstract::Extensive season-by-season sampling was used to establish the normal range of whole-body Na+ and Cl- and Na+ uptake in healthy populations of two fish species, rainbow trout, Oncorhynchus mykiss, and fathead minnow, Pimephales promelas, of known differences in sensitivity to ionoregulatory toxicants (low pH, trace met...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::Silencing genes of a pest with double-stranded RNA (dsRNA) is a promising new pest management technology. As part of the environmental risk assessment for dsRNA-based products, the environmental fate and the potential for adverse effects to on-target organisms should be characterized. In the present study, a nonbioact...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3648
更新日期:2017-05-01 00:00:00
abstract::The risk associated with wood extractives, biocides, and other additives in pulp and paper mill effluents was evaluated by performing a characterization of process waters and effluents in terms of toxicity and chemical analysis. The individual toxicity of 10 resin acids, two unsaturated fatty acids, and three biocides...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/02-632
更新日期:2004-02-01 00:00:00
abstract::Traditional risk assessment guidelines employ acute or chronic toxicity tests for a maximum of one generation of organisms. These tests are usually performed in the laboratory at a constant standard temperature, although in the field organisms may experience different temperatures, which may be a source of additional ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.1969
更新日期:2012-10-01 00:00:00
abstract::The Strait of Georgia (British Columbia, Canada) is a hydrologically complex inland sea with a rich abundance and diversity of species of aquatic life. Marine sediments, as both a sink for hydrophobic contaminants and a potential source for aquatic food webs, were collected from 41 sites throughout the 6,900-km(2) Str...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.542
更新日期:2011-07-01 00:00:00
abstract::To gain new insight into the mechanism of selective cytotoxicity of benzoylureas as insecticides, the in vitro mode of action of chlorfluazuron was investigated on lepidopteran Tn5B1-4 and Sf-21 cells and human Hek293 and HepG2 cells. Chlorfluazuron inhibited the proliferation of Tn5B1-4 and Sf-21 cells with 50% inhib...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2969
更新日期:2015-07-01 00:00:00
abstract::We examined the effects of multigenerational exposure of mercury (Hg) on Hg toxicity and biokinetics in a population of Daphnia magna. After chronic Hg exposure at 3.8 microg Hg/L, the first generation (F0) adults had an elevated 24-h median lethal concentration (LC50) of Hg (76 microg/L) when compared to the control ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/05-085r.1
更新日期:2005-11-01 00:00:00
abstract::Global climate change (GCC) is likely to alter the degree of human exposure to pollutants and the response of human populations to these exposures, meaning that risks of pollutants could change in the future. The present study, therefore, explores how GCC might affect the different steps in the pathway from a chemical...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.2046
更新日期:2013-01-01 00:00:00
abstract::The present study characterized the chronic effect of binary-metal mixtures of cadmium (Cd) and zinc (Zn) on Daphnia magna. The titration design was chosen to characterize the 21-d chronic effects of the binary-metal mixtures on survival, growth, reproduction, and metal accumulation in D. magna. Using this design, inc...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3830
更新日期:2017-10-01 00:00:00
abstract::Currently, environmental studies describing levels of polychlorinated biphenyls (PCBs) in imported shrimp are limited, particularly studies of aquaculture shrimp. In the present study, we measured concentrations of the 209 PCB congeners in 84 uncooked, warm-water shrimp samples from the United States and 14 other coun...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.1803
更新日期:2012-05-01 00:00:00
abstract::Standard U.S. Environmental Protection Agency (U.S. EPA) statistical analyses of whole effluent toxicity tests involve the estimation of the concentration associated with a specified level of inhibition relative to control responses. Current U.S. EPA estimation methods (linear interpolation or probit-based methods) ar...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::Current regulation of metals in soils is based on total metal concentrations rather than on actual exposure concentrations. Considering the extreme variation in soil physicochemical properties, total concentrations are not reflective of the availability and resultant toxicity of metals in different soils. In this stud...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::The paucity of information on the occurrence of pharmaceuticals in the environment in African countries led the authors to investigate 8 acidic pharmaceuticals (4 antipyretics, 3 antibiotics, and 1 lipid regulator) in wastewater, surface water, and sediments from the Msunduzi River in the province of KwaZulu-Natal, So...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3144
更新日期:2016-01-01 00:00:00
abstract::Various statistical tests on concentration data serve to support decision-making regarding characterization and monitoring of contaminated media, assessing exposure to a chemical, and quantifying the associated risks. However, the routine statistical protocols cannot be directly applied because of challenges arising f...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章,评审
doi:10.1002/etc.4046
更新日期:2018-03-01 00:00:00
abstract::Equilibrium distribution models of hydrophobic neutral partitioning of the perfluorinated carboxylic and sulfonic acids were shown, without the need for any physical chemical properties, to successfully predict the sediment-water distribution (D(SW) ) directly from independently measured equilibrium tissue distributio...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.637
更新日期:2011-10-01 00:00:00
abstract::Freshwater mussels, one of the most imperiled groups of animals in the world, are generally underrepresented in toxicity databases used for the development of ambient water quality criteria and other environmental guidance values. Acute 96-h toxicity tests were conducted to evaluate the sensitivity of 5 species of juv...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3642
更新日期:2017-03-01 00:00:00
abstract::Ab initio gene prediction and evidence alignment were used to produce the first annotations for the fathead minnow (Pimephales promelas) genome. We also describe a genome browser, hosted by the Society of Environmental Toxicology and Chemistry, that provides simplified access to the annotation data in context with the...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3929
更新日期:2017-12-01 00:00:00
abstract::Extensive agricultural use of neonicotinoid insecticide products has resulted in the presence of neonicotinoid mixtures in surface waters worldwide. Although many aquatic insect species are known to be sensitive to neonicotinoids, the impact of neonicotinoid mixtures is poorly understood. In the present study, the cum...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.3878
更新日期:2017-11-01 00:00:00
abstract::The E,E-(4,4'-bis[2-sulfostyryl]biphenyl) (DSBP) is a fluorescent whitening agent widely used by the textile and detergent industries to whiten fabrics. Hypochlorite used to bleach fabrics oxidizes DSBP slowly at room temperature and in a higher rate at 60 degrees C. The ions of metals such as Fe, Cu, and Mn accelerat...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract::The relationship between the physiological state of fungi and the response of their functional system to metals is not known, limiting the use of fungal enzymes as tools for assessing metal ecotoxicity in terrestrial ecosystems. The present study attempts to establish how the development phases modulate the secretion ...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1002/etc.101
更新日期:2010-04-01 00:00:00
abstract::Hexanitrohexaazaisowurtzitane (CL-20), a new polycyclic polynitramine, has the same functional nitramine groups (N-NO2) as the widely used energetic chemicals hexahydro-1,3,5-trinitro-1,3,5-triazacyclohexane (royal demolition explosive [RDX]) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (high-melting explosive...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/054-188r.1
更新日期:2005-10-01 00:00:00
abstract::A method is presented for developing scientifically defensible, numeric guidelines for residual petroleum-related constituents, specifically monocyclic aromatic hydrocarbons (MAHs) and polycyclic aromatic hydrocarbons (PAHs), in the water column. The guidelines are equivalent to a HC5 (i.e., hazard concentration to 5%...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/08-271.1
更新日期:2009-06-01 00:00:00
abstract::DNA microarray technology enables genome-wide detection of cell response at the transcriptional level. We are planning to make bioassay systems that can detect environmental chemicals to screen for potential bioreactive agents. To develop a DNA microarray for our purposes, the changes in gene expression underlying the...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/1551-5028(2001)020<2353:bocuad>2.0.co;2
更新日期:2001-10-01 00:00:00
abstract::Aqueous suspensions of fullerene aggregates (aqua-nC60) were used to investigate the movement of carbon-based nanomaterials in a marine water column and to determine their effects on different life stages of a marine teleost. Fullerene aggregates formed precipitates as a result of mixing in natural seawater, and level...
journal_title:Environmental toxicology and chemistry
pub_type: 杂志文章
doi:10.1897/07-632.1
更新日期:2008-09-01 00:00:00