Toward improved analysis of concentration data: Embracing nondetects.

abstract：:Most toxicity tests investigate constant concentrations of a chemical. Concentrations of many compounds in the environment are dynamic, however, and individuals may be more sensitive to pulses of a chemical initiated at specific points during development. Realistic toxicity tests are important to accurately assess the...

journal_title：Environmental toxicology and chemistry

authors： Earl JE,Whiteman HH

更新日期：2009-06-01 00:00:00

abstract：:A method is presented for developing scientifically defensible, numeric guidelines for residual petroleum-related constituents, specifically monocyclic aromatic hydrocarbons (MAHs) and polycyclic aromatic hydrocarbons (PAHs), in the water column. The guidelines are equivalent to a HC5 (i.e., hazard concentration to 5%...

journal_title：Environmental toxicology and chemistry

authors： McGrath JA,Di Toro DM

更新日期：2009-06-01 00:00:00

abstract：:This article reports the results of various biodegradation experiments on polychlorinated biphenyl (PCB)-contaminated sandy soil employing a mixed culture of acclimatized bacteria. Following the optimization of different variables without chemical pretreatment, the elimination rate achieved of Aroclor 1242 in slurry-p...

journal_title：Environmental toxicology and chemistry

authors： Manzano MA,Perales JA,Sales D,Quiroga JM

更新日期：2003-04-01 00:00:00

abstract：:Exposure of Daphnia pulex to the insecticide and juvenile hormone-mimic methoprene resulted in a decrease in the incidence of all-male broods and an increase in the incidence of all-female broods compared with controls. These effects were observed at nominal concentrations of 10 and 100 microg/L, within the upper rang...

journal_title：Environmental toxicology and chemistry

authors： Peterson JK,Kashian DR,Dodson SI

更新日期：2001-03-01 00:00:00

abstract：:We quantified the uncertainty due to biota-related parameters in estimated bioaccumulation factors (BAFs) of persistent organic pollutants for fish through Monte Carlo simulations. For this purpose, the bioaccumulation model OMEGA (Optimal Modeling for EcotoxicoloGical Applications) was parameterized based on data fro...

journal_title：Environmental toxicology and chemistry

authors： Hauck M,Hendriks HW,Huijbregts MA,Ragas AM,van de Meent D,Hendriks AJ

更新日期：2011-02-01 00:00:00

abstract：:Pesticides are frequently detected in urban streams, with concentrations often exceeding those reported in surface waters within agricultural areas. The authors studied growth, survival, and return rates of coho salmon (Oncorhynchus kisutch) smolts exposed to a pesticide mixture ("cocktail") representative of the pest...

journal_title：Environmental toxicology and chemistry

authors： King KA,Grue CE,Grassley JM,Fisk RJ,Conquest LL

更新日期：2014-07-01 00:00:00

abstract：:To investigate possible relationships between polychlorinated biphenyl (PCB) exposure and infectious disease mortality in harbor porpoises (Phocoena phocoena) in United Kingdom waters, summed blubber concentrations of 25 chlorobiphenyl congeners (sigma25CB) in healthy harbor porpoises that died of acute physical traum...

journal_title：Environmental toxicology and chemistry

authors： Jepson PD,Bennett PM,Deaville R,Allchin CR,Baker JR,Law RJ

更新日期：2005-01-01 00:00:00

abstract：:A major problem with risk assessment of chemicals is the extrapolation of laboratory single-species toxicity tests, which oversimplify the actual field situation by ignoring species interactions, to natural communities. The authors tested if the bioavailability-normalized 5% hazardous concentration (HC5) estimated fro...

journal_title：Environmental toxicology and chemistry

authors： Van de Perre D,Roessink I,Janssen CR,Smolders E,Van Regenmortel T,Van Wichelen J,Vyverman W,Van den Brink PJ,De Schamphelaere KA

更新日期：2016-11-01 00:00:00

abstract：:3-Methyl-4-nitrophenol (PNMC) is a component of diesel exhaust particles and one of the major breakdown products of the insecticide fenitrothion. This chemical has a high potential for reproductive toxicity in Japanese quail (Coturnix japonica) and rats. Because PNMC inhaled by the body is metabolized by uridine dipho...

journal_title：Environmental toxicology and chemistry

authors： Lee CH,Kamijima M,Li C,Taneda S,Suzuki AK,Nakajima T

更新日期：2007-09-01 00:00:00

abstract：:Environmental contaminants can interfere with hormonal regulation in both vertebrates and invertebrates, and these contaminants may disrupt the endocrine system of human and other organisms. Evidence is growing that contaminants may be partly responsible for the observed increase of disease in marine organisms by adve...

journal_title：Environmental toxicology and chemistry

authors： Thilagam H,Gopalakrishnan S,Bo J,Wang KJ

更新日期：2009-08-01 00:00:00

abstract：:Daphnia magna is a widely used model organism for aquatic toxicity testing. In the present study, the authors investigated the hydrolytic enzyme activity of D. magna after exposure to toxicant stress. In vivo enzyme activity was quantified using 15 fluorogenic enzyme probes based on 4-methylumbelliferyl or 7-amino-4-m...

journal_title：Environmental toxicology and chemistry

authors： Ørsted M,Roslev P

更新日期：2015-08-01 00:00:00

abstract：:Given the urgent need for ecologically relevant toxicity tools specific to estuarine systems, the main goal of the present study was to develop and evaluate the potential of an in situ algal assay for estuarine sediment-overlying water toxicity evaluations using the microalga Phaeodactylum tricornutum immobilized in a...

journal_title：Environmental toxicology and chemistry

authors： Moreira SM,Guilhermino L,Ribeiro R

更新日期：2006-09-01 00:00:00

abstract：:The present study assessed and compared the oxidative and reductive biotransformation of brominated flame retardants, including established polybrominated diphenyl ethers (PBDEs) and emerging decabromodiphenyl ethane (DBDPE) using an in vitro system based on liver microsomes from various arctic marine-feeding mammals:...

journal_title：Environmental toxicology and chemistry

authors： McKinney MA,Dietz R,Sonne C,De Guise S,Skirnisson K,Karlsson K,Steingrímsson E,Letcher RJ

更新日期：2011-07-01 00:00:00

abstract：:The present study characterized the chronic effect of binary-metal mixtures of cadmium (Cd) and zinc (Zn) on Daphnia magna. The titration design was chosen to characterize the 21-d chronic effects of the binary-metal mixtures on survival, growth, reproduction, and metal accumulation in D. magna. Using this design, inc...

journal_title：Environmental toxicology and chemistry

authors： Pérez E,Hoang TC

更新日期：2017-10-01 00:00:00

abstract：:Many habitats may be exposed to multiple chemical contaminants, particularly in agricultural areas where fertilizer and pesticide use are common; however, the singular and interactive effects of contaminants are not well understood. The objective of our study was to examine how realistic, sublethal environmental level...

journal_title：Environmental toxicology and chemistry

authors： Boone MD,Bridges CM,Fairchild JF,Little EE

更新日期：2005-05-01 00:00:00

abstract：:Scientific reviews and studies continue to describe omics technologies as the next generation of tools for environmental monitoring, while cautioning that there are limitations and obstacles to overcome. However, omics has not yet transitioned into national environmental monitoring programs designed to assess ecosyste...

journal_title：Environmental toxicology and chemistry

authors： Bahamonde PA,Feswick A,Isaacs MA,Munkittrick KR,Martyniuk CJ

更新日期：2016-01-01 00:00:00

abstract：:The fate and effects of cytostatic (anticancer or antineoplastic) pharmaceuticals in the environment are largely unknown, but they can contaminate wastewater treatment effluents and consequently aquatic ecosystems. In this paper, we have focused on five cytostatic compounds used in high amounts (cyclophosphamide, cisp...

journal_title：Environmental toxicology and chemistry

authors： Zounková R,Odráska P,Dolezalová L,Hilscherová K,Marsálek B,Bláha L

更新日期：2007-10-01 00:00:00

abstract：:Perfluorooctanesulfonic acid (PFOS) is a perfluorinated compound used in many industrial and consumer products. It has been linked to a broad range of adverse effects in several species, including zebrafish (Danio rerio). The zebrafish embryo is a widely used vertebrate model to elucidate potential adverse effects of ...

journal_title：Environmental toxicology and chemistry

authors： Mylroie JE,Wilbanks MS,Kimble AN,To KT,Cox CS,McLeod SJ,Gust KA,Moore DW,Perkins EJ,Garcia-Reyero N

更新日期：2020-10-12 00:00:00

abstract：:During the past two decades, the phenomenon of hormesis has gained increased recognition. To promote research in hormesis, a sound statistical quantification of important parameters, such as the level and significance of the increase in response and the range of concentration where it occurs, is strongly needed. Here,...

journal_title：Environmental toxicology and chemistry

authors： Cedergreen N,Ritz C,Streibig JC

更新日期：2005-12-01 00:00:00

abstract：:Methods for the assessment of ecological risks associated with exposure to defined mixtures of toxicants are reviewed and formalized for single-species toxicity. Depending on the modes of action of toxicants in a mixture, these methods apply either the model for concentration additivity (CA) or the model for response ...

journal_title：Environmental toxicology and chemistry

authors： De Zwart D,Posthuma L

更新日期：2005-10-01 00:00:00

abstract：:The present study assessed the effects of maternal copper or cadmium exposure in a live-bearing fish. After a 10-d exposure to background levels (control) or 0.15 μM copper or cadmium, gravid females were transferred to clean water. Once a female gave birth, the authors analyzed her newborn offspring for lipid peroxid...

journal_title：Environmental toxicology and chemistry

authors： Cazan AM,Klerks PL

更新日期：2015-06-01 00:00:00

abstract：:Biofilms can make good bioindicators and biomarkers, offering a convenient tool to monitor metal contamination in streams that results from mine tailing sites. Biofilm metal content (Cu, Zn, Cd, Pb) as well as diatom diversity and the presence of teratologies (diatom abnormalities) were determined for biofilms from ri...

journal_title：Environmental toxicology and chemistry

authors： Leguay S,Lavoie I,Levy JL,Fortin C

更新日期：2016-06-01 00:00:00

abstract：:A comprehensive gas chromatographic-high-resolution mass spectrometric (GC-HRMS)-based method was developed that permitted the simultaneous determination of 30 estrogenic endocrine-disrupting chemicals (EDCs) and related compounds, including surfactants, biogenic and synthetic steroids, fecal sterols, phytoestrogens, ...

journal_title：Environmental toxicology and chemistry

authors： Ikonomou MG,Cai SS,Fernandez MP,Blair JD,Fischer M

更新日期：2008-02-01 00:00:00

abstract：:Heavy metals can cause a decrease in the taxonomic diversity of soil communities. Because of functional redundancy, it remains unclear to what extent different functions performed by the soil microbial communities may be affected by pollution. We studied the impact of metal contamination on soil bacterial and fungal f...

journal_title：Environmental toxicology and chemistry

authors： Stefanowicz AM,Niklińska M,Laskowski R

更新日期：2008-03-01 00:00:00

abstract：:Multispecies stream microcosms were used to test the toxicity of the pyrethroid fenvalerate (FV) associated with suspended particles in order to simulate a typical runoff exposure scenario. Stream microcosms were exposed for 1 h in triplicate to 0.0, 13.6, 136, or 1,365 microg/kg FV and effects were monitored for 93 d...

journal_title：Environmental toxicology and chemistry

authors： Schulz R,Liess M

更新日期：2001-04-01 00:00:00

abstract：:We evaluated the utility of gene-transcriptional responses in the liver of mosquitofish (Gambusia affinis), a species introduced to many countries and therefore widely available, for detecting endocrine-disrupting activity in water. Exposure to β-naphthoflavone, an aryl hydrocarbon receptor (AhR) agonist, significantl...

journal_title：Environmental toxicology and chemistry

authors： Kamata R,Itoh K,Nakajima D,Kageyama S,Sawabe A,Terasaki M,Shiraishi F

更新日期：2011-12-01 00:00:00

abstract：:The current study describes the effect of cypermethrin, fluoxetine, and thiabendazole, at environmentally relevant concentrations, on the expression of heat shock protein 70 (HSP70) and interleukin 1β (IL-1β), using Xenopus laevis larvae as animal model. Cytokines and interleukins are considered good predictors of the...

journal_title：Environmental toxicology and chemistry

authors： Martini F,Fernández C,Segundo LS,Tarazona JV,Pablos MV

更新日期：2010-11-01 00:00:00

abstract：:Military activities associated with training have resulted in soil residues of munition compounds and their breakdown products. Often, these areas are valuable habitats used by birds. To evaluate the possibility of adverse effects in birds, the effects from oral exposures of 2,6-dinitrotoluene (2,6-DNT) and 1,3,5-trin...

journal_title：Environmental toxicology and chemistry

authors： Johnson MS,Quinn MJ,Bazar MA,Gust KA,Escalon BL,Perkins EJ

更新日期：2007-07-01 00:00:00

abstract：:The ecotoxicological effects of octachlorostyrene (OCS) on the aquatic larvae of the nonbiting midges Chironomus riparius (Diptera, Chironomidae) were investigated by evaluating their responses in various biological organizations, from the molecular and biochemical to the ecophysiological levels. The results of the 24...

journal_title：Environmental toxicology and chemistry

authors： Lee SW,Park K,Hong J,Choi J

更新日期：2008-05-01 00:00:00

abstract：:Many chiral pesticides are introduced into the environment as racemates, although their pesticidal activity is usually the result of preferential reactivity of only one enantiomer, while the other enantiomer may have toxic effects against nontarget organisms. Methamidophos (O,S-dimethyl phosphoramidothioate), a chiral...

journal_title：Environmental toxicology and chemistry

authors： Emerick GL,Oliveira RV,Belaz KR,Gonçalves M,DeOliveira GH

更新日期：2012-02-01 00:00:00