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General anxiety symptoms after acute lung injury: predictors and correlates.

Abstract：

OBJECTIVE:Acute lung injury (ALI) is common in the intensive care unit (ICU), typically requiring life support ventilation. Survivors often experience anxiety after hospital discharge. We evaluated general anxiety symptoms 3 months after ALI for: (1) associations with patient characteristics and ICU variables, and (2) cross-sectional associations with physical function and quality of life (QOL). METHODS:General anxiety was assessed as part of a prospective cohort study recruiting patients from 13 ICUs at four hospitals in Baltimore, MD using the Hospital Anxiety and Depression Scale--Anxiety Subscale (HAD-A), with associations evaluated using multivariable linear and logistic regression models. RESULTS:Of 152 patients, 38% had a positive screening test for general anxiety (HAD-A≥8). Pre-ICU body mass index and psychiatric comorbidity were associated with general anxiety (OR, 95% confidence interval (CI): 1.06 (1.00, 1.13) and 3.59 (1.25, 10.30), respectively). No ICU-related variables were associated with general anxiety. General anxiety was associated with the number of instrumental ADL dependencies (Spearman's rho=0.22; p=0.004) and worse overall QOL as measured by EQ-5D visual analog scale (VAS) (rho=-0.34; p<0.001) and utility score (rho=-0.30; p<0.001), and by the SF-36 mental health domain (rho=-0.70; p<0.001) and Mental Component Summary score (rho=-0.73; p<0.001). CONCLUSION:Many patients have substantial general anxiety symptoms 3 months after ALI. General anxiety was associated with patient characteristics and impaired physical function and quality of life. Early identification and treatment of general anxiety may enhance physical and emotional function in patients surviving critical illnesses.

journal_name

J Psychosom Res

journal_title

Journal of psychosomatic research

authors

Stevenson JE,Colantuoni E,Bienvenu OJ,Sricharoenchai T,Wozniak A,Shanholtz C,Mendez-Tellez PA,Needham DM

doi

10.1016/j.jpsychores.2013.06.002

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

287-93

issue

3

eissn

0022-3999

issn

1879-1360

pii

S0022-3999(13)00234-1

journal_volume

75

pub_type

杂志文章,多中心研究

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