Lithium Toxicity with Severe Bradycardia Post Sleeve Gastrectomy: a Case Report and Review of the Literature.

Abstract:

:Lithium is one of the major treatment options in bipolar disorder. Bariatric surgery can significantly modify the oral bioavailability of drugs, and lithium is no exception; although in most cases drug absorption seems to decrease, in the case of lithium, toxicity is the risk. In this article, we describe a 61-year-old male patient presented with lithium toxicity, including newly diagnosed severe bradycardia requiring a permanent pacemaker, after undergoing sleeve gastrectomy. We discuss the mechanisms behind this case, provide potential solutions for clinicians treating bariatric patients with lithium, and review previous reports of lithium toxicity post bariatric surgery. Awareness of changes in drug absorption, particularly lithium, following bariatric surgery, is prudent and essential for optimal patient care. Close clinical and drug levels monitoring is strongly advised.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Dahan A,Porat D,Azran C,Mualem Y,Sakran N,Abu-Abeid S

doi

10.1007/s11695-018-3597-x

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

735-738

issue

2

eissn

0960-8923

issn

1708-0428

pii

10.1007/s11695-018-3597-x

journal_volume

29

pub_type

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