Abstract:
:Single-anastomosis duodenoileal bypass with sleeve gastrectomy (SADI-S) is a simplified biliopancreatic diversion. The objective of this study was to develop a reproducible animal model for SADI-S. We used three techniques for duodenal exclusion and duodenoileal anastomosis: (a) surgical clip and side-to-side anastomosis, (b) ligation and side-to-side anastomosis and (c) sectioning the duodenum, closing the duodenal stump and end-to-side anastomosis. We recorded the surgical technique and complications for each method. Twenty-five of 31 rats survived to the end of the study period. One death occurred from accidental anaesthesia overdose and the others from anastomosis leak. Four duodenal exclusions had repermeabilised at necropsy. Our murine model of SADI-S can be consistently reproduced. Sectioning the duodenum is preferable to avoid repermeabilisation of the duodenum.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Laura M,Mylene L,Christophe B,Boris H,Christophe M,Konstantinos Adoi
10.1007/s11695-018-3254-4subject
Has Abstractpub_date
2018-07-01 00:00:00pages
2122-2125issue
7eissn
0960-8923issn
1708-0428pii
10.1007/s11695-018-3254-4journal_volume
28pub_type
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