Ascitic cholesterol is superior to serum-ascites albumin gradient in the detection of non-portal hypertensive ascites and the diagnosis of mixed ascites.

abstract：BACKGROUND:There is clear benefit from combination therapy with infliximab and immunosuppressive drugs (IS), but few data are available for adalimumab (ADA). AIM:To assess the efficacy of ADA monotherapy and ADA+IS for induction and maintenance therapy in Crohn's disease. METHODS:Retrospective study of patients with ...

journal_title：Alimentary pharmacology & therapeutics

authors： Reenaers C,Louis E,Belaiche J,Seidel L,Keshav S,Travis S

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Epidemiological data concerning hepatitis B are scarce in France. AIM:To describe epidemiological, clinical, virological and histological features of HBsAg-positive patients followed at non-academic hospitals in France. METHODS:Clinical, biological, virological and histological data of all HBsAg-positive c...

journal_title：Alimentary pharmacology & therapeutics

authors： Cadranel JF,Lahmek P,Causse X,Bellaiche G,Bettan L,Fontanges T,Medini A,Henrion J,Chousterman M,Condat B,Hervio P,Periac P,Eugène C,Moindrot H,Grasset D,Nouel O,Pilette C,Szostak-Talbodec N,Cayla JM,Si-Ahmed SN,Du

更新日期：2007-08-15 00:00:00

abstract：BACKGROUND:None of the proposed materials tested for the management of perianal fistulae has proven to be a definitive treatment. AIM:To assess a new repair scaffold and drug delivery device conceived to target perianal fistula repair. METHODS:Poly(D,L-lactide-co-glycolide) porous microspheres containing either antib...

journal_title：Alimentary pharmacology & therapeutics

authors： Blaker JJ,Pratten J,Ready D,Knowles JC,Forbes A,Day RM

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Patients with chronic hepatitis C virus and advanced fibrosis or cirrhosis are at risk for disease progression and hepatic decompensation. AIM:To determine the effects on hepatic histology of treatment with peginterferon alfa-2a (90 or 180 mug/week) or interferon alfa-2a (3 million units three times weekly)...

journal_title：Alimentary pharmacology & therapeutics

authors： Everson GT,Balart L,Lee SS,Reindollar RW,Shiffman ML,Minuk GY,Pockros PJ,Govindarajan S,Lentz E,Heathcote EJ

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:In cirrhosis, portal hypertension is associated with a spectrum of renal dysfunction that has significant implications for morbidity and mortality. AIM:To discuss recent progress in the patho-physiological mechanisms and therapeutic options for portal hypertension-related renal dysfunction. METHODS:A liter...

journal_title：Alimentary pharmacology & therapeutics

authors： Leithead JA,Hayes PC,Ferguson JW

更新日期：2014-04-01 00:00:00

abstract：AIM:To compare the efficacy of ranitidine bismuth citrate plus clarithromycin (RBC-C) vs. omeprazole plus amoxycillin (OME-AMO) in the cure of Helicobacter pylori infection. METHODS:In this double-blind, multicentre, parallel-group study 122 H. pylori-positive patients with active duodenal ulcer or gastritis, with con...

journal_title：Alimentary pharmacology & therapeutics

authors： Kolkman JJ,Tan TG,Oudkerk Pool M,Van Kleef WA,Geraedts AA,Timmerman RJ,Crobach LF,Nicolai JJ,Wolff AA,Van Der Laan J

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Interferon might induce mutation in regions of hepatitis B virus DNA that encode for immunologic target of cytotoxic T lymphocytes. AIM:To investigate the short-term effect of steroid priming and interferon therapy on hepatitis B virus, we followed the nucleotide changes in the precore and core region of he...

journal_title：Alimentary pharmacology & therapeutics

authors： How W,Ng WC,Tan MF,Seet BL,Guan R

更新日期：1996-04-01 00:00:00

abstract：:It is not known whether hypoxia, associated with upper gastrointestinal endoscopic procedures when midazolam sedation is used without narcotics, persists into the post-procedure recovery period. Thirty consecutive patients aged over 60 years, undergoing ERCP using midazolam sedation alone, were monitored clinically an...

journal_title：Alimentary pharmacology & therapeutics

authors： Haines DJ,Bibbey D,Green JR

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:There are limited data concerning infliximab drug monitoring during de-escalation of the treatment of inflammatory bowel disease (IBD). AIM:To define the rate and the predictors of relapse following infliximab de-escalation in IBD patients in remission. METHODS:All IBD patients at a single referral centre ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lucidarme C,Petitcollin A,Brochard C,Siproudhis L,Dewitte M,Landemaine A,Bellissant E,Bouguen G

更新日期：2019-01-01 00:00:00

abstract：:Renal function abnormalities and ascites in cirrhosis are the final consequence of a circulatory dysfunction characterized by marked splanchnic arterial vasodilation. This causes a reduction in effective arterial blood volume and the homoeostatic activation of vasoconstrictor and sodium-retaining systems. Albumin is v...

journal_title：Alimentary pharmacology & therapeutics

authors： Ginès P,Guevara M,De Las Heras D,Arroyo V

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Transplacental transfer of tumour necrosis factor-alpha (TNF-α) inhibitors has been shown in mothers receiving therapy for inflammatory bowel disease (IBD). AIM:To examine reports of adverse events of these medications in pregnancy. METHODS:Individual Safety Reports of adverse events (Jan 2003-June 2012) w...

journal_title：Alimentary pharmacology & therapeutics

authors： Deepak P,Stobaugh DJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:With the global efforts to eradicate hepatitis C virus (HCV), treatment during pregnancy is becoming a priority for research as this, and maternal cure should reduce vertical transmission. However, as information on the efficacy and safety of direct-acting antivirals (DAAs) in pregnancy is generally lacking,...

journal_title：Alimentary pharmacology & therapeutics

authors： Freriksen JJM,van Seyen M,Judd A,Gibb DM,Collins IJ,Greupink R,Russel FGM,Drenth JPH,Colbers A,Burger DM

更新日期：2019-10-01 00:00:00

abstract：:Six asymptomatic, non-smoking men with endoscopically proven duodenal ulcer disease received single nocturnal doses of placebo, 40 mg famotidine and 300 mg ranitidine each for 1 week prior to serial measurement of pH, peptic activity and serum gastrin concentrations over 24 h and of acid output. The intragastric pH fl...

journal_title：Alimentary pharmacology & therapeutics

authors： Thomson AB,Pinchbeck BR,Kirdeikis J,Zuk L,Marriage B,Prat A

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:The efficacy of each probiotic should be evaluated separately. Previously, we have shown that Lactobacillus GG (LGG) is effective in treating acute gastroenteritis (AGE) in children. AIM:To update our 2007 meta-analysis on the effectiveness of LGG in treating AGE in children. METHODS:The Cochrane Library, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Szajewska H,Skórka A,Ruszczyński M,Gieruszczak-Białek D

更新日期：2013-09-01 00:00:00

abstract：AIM:To compare lansoprazole 30 mg daily with ranitidine 150 mg b.d. in the treatment of acid-related dyspepsia in general practice. METHODS:In a double-blind, parallel group, randomized, mutlicentre study conducted in 32 general practices in the UK, 213 patients were randomized to receive lansoprazole 30 mg daily, and...

journal_title：Alimentary pharmacology & therapeutics

authors： Jones RH,Baxter G

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The agreement between subtyping irritable bowel syndrome (IBS) patients based on Rome II criteria versus Rome III criteria is unknown. AIM:To compare IBS subtyping based on Rome II versus III criteria. METHODS:The Rome II Modular Questionnaire and the Bristol Stool Form Scale (one-week diary cards) were co...

journal_title：Alimentary pharmacology & therapeutics

authors： Ersryd A,Posserud I,Abrahamsson H,Simrén M

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND:The nonselective 5-HT(4) receptor agonists, cisapride and tegaserod have been associated with cardiovascular adverse events (AEs). AIM:To perform a systematic review of the safety profile, particularly cardiovascular, of 5-HT(4) agonists developed for gastrointestinal disorders, and a nonsystematic summary ...

journal_title：Alimentary pharmacology & therapeutics

authors： Tack J,Camilleri M,Chang L,Chey WD,Galligan JJ,Lacy BE,Müller-Lissner S,Quigley EM,Schuurkes J,De Maeyer JH,Stanghellini V

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:KC 11458, a motilin agonist without antibiotic properties, accelerates gastric emptying in animals and healthy humans. AIM:To evaluate the acute effects of KC 11458 on gastric emptying in diabetic gastroparesis. METHODS:Twenty-nine patients (6 type 1 and 23 type 2) with gastroparesis underwent assessments ...

journal_title：Alimentary pharmacology & therapeutics

authors： Russo A,Stevens JE,Giles N,Krause G,O'Donovan DG,Horowitz M,Jones KL

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Haemorrhage from ruptured oesophageal varices is a common cause of death in people with cirrhosis. Guidelines recommend screening for varices at time of cirrhosis diagnosis and throughout the course of the disease. Conventional gastroscopy is the criterion standard for variceal screening; however, is invasiv...

journal_title：Alimentary pharmacology & therapeutics

authors： Wickremeratne T,Turner S,O'Beirne J

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Activation of human and non-human colonic beta(beta)3-adrenoceptors causes smooth muscle relaxation. beta3-Adrenoceptor agonists protect against experimental indomethacin-induced jejunal ulceration. The mechanism of protection may involve spasmolytic/vasodilatory agonist activity. The precise localization of...

journal_title：Alimentary pharmacology & therapeutics

authors： Anthony A,Schepelmann S,Guillaume JL,Strosberg AD,Dhillon AP,Pounder RE,Wakefield AJ

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:No prognostic tools are established for alcohol-related liver disease (ALD). Collagen proportionate area (CPA) measurement is a technique that quantifies fibrous tissue in liver biopsies using digital image analysis. AIM:To assess the predictive value of CPA on hepatic decompensation and liver-related morta...

journal_title：Alimentary pharmacology & therapeutics

authors： Israelsen M,Guerrero Misas M,Koutsoumourakis A,Huang Y,Thiele M,Hall A,Rasmussen D,Covelli C,Buzzetti E,Prat LI,Roccarina D,Detlefsen S,Luong TV,Quaglia A,Krag A,Jeffrey G,Pinzani M,Tsochatzis EA

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The long-term outcome of percutaneous acetic acid injection (PAI) and percutaneous ethanol injection (PEI) for treating small hepatocellular carcinoma (HCC) remains unclear. AIM:To compare the long-term outcome of PAI vs. PEI for treating small HCC. METHODS:From July 1998 to July 2004, 125 patients with sm...

journal_title：Alimentary pharmacology & therapeutics

authors： Tsai WL,Cheng JS,Lai KH,Lin CP,Lo GH,Hsu PI,Yu HC,Lin CK,Chan HH,Chen WC,Chen TA,Li WL,Liang HL

更新日期：2008-08-01 00:00:00

abstract：AIM:To evaluate (i) the diagnostic usefulness of a delayed test in initially negative patients; and (ii) the reliability of the rapid urease test, histology or a combination of the two to diagnose Helicobacter pylori during emergency endoscopy in a large clinical practice series. PATIENTS AND METHODS:Records of patien...

journal_title：Alimentary pharmacology & therapeutics

authors： Güell M,Artigau E,Esteve V,Sánchez-Delgado J,Junquera F,Calvet X

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) provide the most effective pharmacotherapy for treating acid-related disorders. However, PPIs do not completely control acid over 24 h with once-daily dosing. AIMS:To discuss limitations inherent in the pharmacokinetics (PK) and pharmacodynamics of conventional PPI formulations...

journal_title：Alimentary pharmacology & therapeutics

authors： Metz DC,Vakily M,Dixit T,Mulford D

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Coeliac disease is associated with an increased risk of lymphoma and small bowel malignancy, but most studies have found no increased risk of colorectal cancer. AIM:To compare the prevalence of colorectal adenomas in coeliac disease patients with that in non-coeliac disease controls. METHODS:We identified ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lebwohl B,Stavsky E,Neugut AI,Green PH

更新日期：2010-10-01 00:00:00

abstract：AIM:To systematically review the literature evaluating hypnotherapy in the management of irritable bowel syndrome (IBS). METHODS:Electronic databases were searched (Cochrane Library, Medline, CINAHL, AMED, Embase, PsycINFO, CISCOM, TRIP and the Social Science Citation index), bibliographic references scanned and main ...

journal_title：Alimentary pharmacology & therapeutics

authors： Wilson S,Maddison T,Roberts L,Greenfield S,Singh S,Birmingham IBS Research Group.

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Conventional interferon monotherapy fails to achieve virological clearance in most hepatitis C-infected patients. The use of high-dose induction regimens may improve the initial clearance of virus, while the addition of ribavirin appears to improve the rates of sustained response once clearance is achieved. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Malik AH,Kumar KS,Malet PF,Ostapowicz G,Adams G,Wood M,Yarbrough K,Jones A,Lee WM

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:We systematically reviewed all available data in the literature to determine the overall eradication rates of currently advised Helicobacter pylori eradication regimens and to resolve conflicting evidence on the impact of antimicrobial resistance on the eradication rates. METHODS:A comprehensive search of a...

journal_title：Alimentary pharmacology & therapeutics

authors： Houben MH,van de Beek D,Hensen EF,de Craen AJ,Rauws EA,Tytgat GN

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The incidence of 'true' re-infection with Helicobacter pylori after successful eradication remains uncertain. AIM:To determine the worldwide rates, risk factors and clinical implications of 'true' re-infection of Helicobacter pylori. 'True' re-infection of H. pylori is defined as the situation where tests f...

journal_title：Alimentary pharmacology & therapeutics

authors： Zhang YY,Xia HH,Zhuang ZH,Zhong J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Although little mortality is associated with irritable bowel syndrome, curative therapy does not exist and thus the economic impact of this disorder may be considerable. METHODS:A systematic review of the literature was performed. Studies were included if their focus was irritable bowel syndrome, and direct...

journal_title：Alimentary pharmacology & therapeutics

authors： Inadomi JM,Fennerty MB,Bjorkman D

更新日期：2003-10-01 00:00:00