Abstract:
INTRODUCTION:Invasive fungal sinusitis (IFS) is a rare but deadly clinical entity that occurs in immunocompromised patients. Diagnosis in children typically requires operative biopsies under general anesthesia, which has associated risks. Findings on bedside nasal endoscopy (BNE) can be used with history, exam, and imaging to determine the need for surgery, however, the accuracy of this tool has not been established among pediatric patients. METHODS:Patients who underwent BNE for evaluation of IFS from 2008 to 2016 at the Children's Hospital of Philadelphia were identified using Current Procedural Terminology (CPT) codes. Retrospective chart analysis was performed and included underlying diagnoses, presenting signs and symptoms, imaging findings, endoscopic findings and outcomes. RESULTS:Nineteen patients were identified who underwent evaluation for IFS using BNE during the period studied. Eight patients had exam findings that were concerning for IFS, including debris or crusting, darkened or pale mucosa, or copious, thick and/or purulent secretions. Immediate operative biopsies and debridement revealed IFS in six of eight patients. Eleven patients had exam findings deemed not concerning for IFS including mucosal edema, mucous without purulence, or normal findings. Six of eleven patients underwent operative biopsy despite negative endoscopy, and five were observed clinically. None of the 11 patients with negative bedside endoscopy developed IFS. CONCLUSIONS:All patients with IFS had concerning exam findings on endoscopy and were treated with immediate biopsies and debridement. No patient with normal or non-concerning findings on BNE progressed to have invasive fungal sinusitis. While suspicion for IFS in immunocompromised children must remain high, BNE is feasible and useful in its assessment.
journal_name
Int J Pediatr Otorhinolaryngoljournal_title
International journal of pediatric otorhinolaryngologyauthors
Mulvey CL,Rizzi MD,Buzi Adoi
10.1016/j.ijporl.2018.09.019subject
Has Abstractpub_date
2018-12-01 00:00:00pages
82-88eissn
0165-5876issn
1872-8464pii
S0165-5876(18)30474-9journal_volume
115pub_type
杂志文章abstract:OBJECTIVES:To analyze the success rates of myringoplasty in children, to assess prognostic factors and to evaluate their interactions in the evolution of myringoplasty. METHODS:Charts of patients who had undergone a myringoplasty between 1997 and 2007 were reviewed for: patient age, sex, perforation side, etiology, si...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2011.03.015
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:There are no reports on the therapeutic effect of Ginkgo biloba extract (GBE) on otitis media-induced labyrinthitis. The present study examined whether GBE can protect against cochlear damage induced by intratympanic instillation of lipopolysaccharide (LPS)-induced labyrinthitis. MATERIALS AND METHODS:Experi...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2011.04.003
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of mandibular osteomyelitis (OM) in patients with congenital insensitivity to pain with anhidrosis (CIPA) and to relate its appearance to possible risk factors. METHODS:The records of 33 patients were reviewed for data concerning events of jaw OM, oral trauma, maxillofacial interve...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2011.01.011
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVES:Referential communication (RC) is a key element in achieving a successful communication. This case series aimed to evaluate RC in children with unilateral cochlear implants (CIs) with formal language skills within the normal range. METHODS AND MATERIALS:A total of 31 children with CIs, with language develop...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2015.02.003
更新日期:2015-04-01 00:00:00
abstract::Keratocystic odontogenic tumors (KCOT) are exceptional in children and adolescents as they usually occur in the third decade. The present study reports the case of a 15 years old girl who was diagnosed with a KCOT that underwent malignant transformation. KCOT diagnostic was based on clinical, radiological, histopathol...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2018.06.042
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To implement a surgeon led initiative for tracheostomy education for non-surgical pediatric first responders in the hospital setting and to assess its efficacy. METHODS:A prospective, observational study conducted from September 2018 to March 2019. All pediatric residents at a tertiary care children's hospit...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2020.109944
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES/HYPOTHESIS:Cochlear implantation is an established method of auditory rehabilitation for severely and profoundly hearing impaired individuals. Although numerous studies have examined communication outcomes in pediatric cochlear implant (CI) recipients, data concerning the benefits of cochlear implantation in...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2007.08.004
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:1. Determine the feasibility of measuring tracheal pH with a novel non-aqueous probe designed for oropharyngeal pH monitoring. 2. Correlate clinical and subclinical laryngopharyngeal reflux aspiration events with esophageal pH measurements. METHODS:Five children with chronic indwelling tracheostomies underg...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2009.04.002
更新日期:2009-07-01 00:00:00
abstract::Pseudohypacusis is the term used for a non-organic or functional hearing loss. The mainstay of diagnosis is a lack of consistency in audiological testing. It is usually easier to diagnose in children than in adults, as children are less able to reproduce consistently erroneous results on repeated testing. Nevertheless...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2005.03.039
更新日期:2005-09-01 00:00:00
abstract::We report two original cases of association of cleft palate and lateral cervico-facial teratoma. We discuss the embryological explanation. The first child presented a cleft palate associated with two cervico-facial localisations of teratoma. The other had Pierre Robin sequence associated with lateropharyngeal teratoma...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2012.05.011
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Comprehensive quantitative evaluation of the intercarotid artery distance (ICD) in the pediatric population has not been sufficiently explored. This study aims to measure the minimal ICDs at multiple levels of the skull base to assess changes in the ICD during development. METHODS:Measurement of the ICDs bet...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2020.110520
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:A controversy exists in the literature regarding better auditory performance of cochlear implanted children with mutations in the Gap-Junction-Protein Beta2 (GJB2) gene. This is partially due to insufficient numbers, lack of proper statistics, etc. As this represents a very important issue for the counsellin...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2010.04.002
更新日期:2010-07-01 00:00:00
abstract::The congenital absence of the epiglottis is a very rare anomaly. We present a patient who has a complete absence of the epiglottis, illustrated with an endoscopic photograph, review the literature and discuss the management of patients with this condition. ...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s0165-5876(98)00082-2
更新日期:1998-10-15 00:00:00
abstract:OBJECTIVE:This study compared the prevalence of sudden deafness (SD) in children to investigate the evolution of pediatric SD during the past two decades. METHODS:From 1996 to 2005, totaling 358 SD patients were experienced. Of them, 25 patients (7%) aged <15 years were assigned to Group A. In contrast, 5 patients (2%...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2019.01.029
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:Two potent mediators of acute inflammation, histamine and leukotriene B4 (LTB4), have been shown to play important roles in the pathogenesis and clinical course of acute otitis media (AOM) in children. The purpose of this study was to evaluate the ability of adjuvant drugs, antihistamine and corticosteroid, i...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-5876(02)00372-5
更新日期:2003-03-01 00:00:00
abstract::The aim of this paper was to verify if the growth of the nasomaxillary complex can be influenced by a purely functional alteration such as nasal obstruction, which was induced experimentally in a genetically controlled animal model. Sixty albino rats were employed. Twenty of them had the right nostril occluded by a sy...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s0165-5876(98)00049-4
更新日期:1998-10-02 00:00:00
abstract:INTRODUCTION:Desmoid-type fibromatosis (DF) is a rare benign lesion known for its local aggressiveness. The tumor management still remains under debate. Primary head and neck (HN), represents the second most prevalently affected sitein children with DF. This study aims to analyze the specificity of HN-DF in children, f...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijporl.2019.04.037
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To compare acoustic, aerodynamic and perceptual voice and speech parameters in thermal welding system tonsillectomy and cold knife tonsillectomy patients in order to determine the impact of operation technique on voice and speech. METHODS:Thirty tonsillectomy patients (22 children, 8 adults) participated in ...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2010.10.020
更新日期:2011-01-01 00:00:00
abstract::Physical illness in children is affected by a variety of factors unique to pediatrics. They include a child's developmental level, family environment and the presence of premorbid behavior patterns. Therefore, pediatric care requires special considerations pertaining to the patient-physician relationship and the poten...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/0165-5876(94)01113-c
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVE:Because of the recent data supporting an immunoregulatory role for vitamin D, we evaluated levels of vitamin D in children undergoing adenotonsillectomies (T&A) and controls. METHODS:We prospectively collected data from 47 children undergoing T&As and 15 undergoing unrelated elective procedures at a tertiary...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2010.06.009
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:To describe clinical findings from a multidisciplinary program for children with permanent hearing loss (PHL). METHODS:Retrospective chart review at a tertiary care children's hospital. PATIENTS:Two hundred patients charts were selected from the population of 260 children with permanent hearing loss presen...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2011.05.019
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVES:To review the outcomes of paediatric patients with laryngotracheal stenosis treated at our institution by laryngotracheal reconstruction (LTR). METHODS:A single surgeon personal series retrospective review of case notes over a 10-year period from a single site tertiary referral paediatric otolaryngology dep...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2007.01.005
更新日期:2007-05-01 00:00:00
abstract::We report a case of worsening respiratory distress associated with opisthotonus secondary to tracheomalacia, a rather unique pathophysiological phenomenon. A 2-month-old male baby was referred to our hospital for respiratory distress syndrome with a noticeable opisthotonus. Examination and investigation confirmed the ...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2013.05.024
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To investigate the association between cleft lip and/or palate and nongenetic factors in Greece. METHODS:We designed a case-control study including 35 patients with nonsyndromic cleft lip and/or palate, retrospectively selected, and 35 control patients matched for prefecture of residence, prospectively selec...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2011.02.018
更新日期:2011-05-01 00:00:00
abstract::The main aim of this study was to describe the changes in acoustic analysis in diagnosing voice disorders in children. The secondary goal was the attempt at differentiation of organic and functional disorders by means of acoustic analysis. The study included 112 children in treated due to laryngeal papilloma, gastro-e...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s0165-5876(00)00411-0
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the results of a newly introduced technique to our Department of endoscopic assisted transcanal myringoplasty applied in tympanic membrane perforation in children of any age and compare them to that of the previously standard microscopic assisted myringoplasty technique. METHODS:A retrospective ...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2015.08.025
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:Children with tracheostomies are medically complex and may be discharged with limited and variably trained home nursing support. When faced with emergencies at home, caregivers must often take the lead role in management, and many lack experience with troubleshooting these emergencies prior to initial disc...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2019.01.020
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:The current study aims to examine the effects of human resource (measured with the perception of health workers' perception towards UNHS), screening equipment, program layout and screening techniques on healthcare practitioners' awareness (measured with knowledge) of universal newborn hearing screening (UNHS)...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2018.03.030
更新日期:2018-06-01 00:00:00
abstract::The Stevens-Johnson syndrome (SJS) is a severe variant of erythema multiforme (EM) that occasionally can rise to systemic upset and possibly compromise life. In this report, we described important oral and dermatologic aspects of a case of SJS triggered by Mycoplasma pneumoniae infection. ...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.ijporl.2012.10.019
更新日期:2013-02-01 00:00:00
abstract::A retrospective analysis was performed on 103 pediatric patients, less than 5 years of age, undergoing tracheotomy at New York Hospital between 1980 and 1990. Charts were reviewed with respect to primary diagnosis, indication for tracheotomy, duration of the tracheotomy, complication rate and mortality rate. Approxima...
journal_title:International journal of pediatric otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/0165-5876(95)01175-b
更新日期:1995-07-01 00:00:00