Abstract：
OBJECTIVE:To investigate the association between cleft lip and/or palate and nongenetic factors in Greece. METHODS:We designed a case-control study including 35 patients with nonsyndromic cleft lip and/or palate, retrospectively selected, and 35 control patients matched for prefecture of residence, prospectively selected from pediatric population hospitalized for abdominal pain or injury. Parents were interviewed about drug uptake, diseases, habits, non-occupational exposure to pollutants, and occupation. Questions covered the period from one year before until three months after conception. RESULTS:High-risk paternal occupations (mostly farmers) were significantly more frequent in cleft lip and/or palate than in controls (p=0.039) and increased significantly the cleft lip and/or palate risk in offspring (OR: 3.00; 95% CI: 1.03-8.70). Maternal occupation did not correlate with cleft lip and/or palate. Parental disease, drugs uptake, hazardous habits, maternal folate supplementation and non-occupational exposure to pollutants did not correlate with cleft lip and/or palate. There was a suggestion of increased risk with maternal passive exposure to tobacco (OR: 1.81; 95% CI: 0.69-4.74) and with residential proximity to industries (OR: 1.70; 95% CI: 0.61-4.74). CONCLUSIONS:Paternal high-risk occupations probably exert a teratogenic effect on spermatogenesis or result in maternal contamination, and deserve specific preventive policies. The relation of smoking and residential proximity to industries with occurrence of cleft lip and/or palate deserves further study.
journal_name
Int J Pediatr Otorhinolaryngoljournal_title
International journal of pediatric otorhinolaryngologyauthors
Mirilas P,Mentessidou A,Kontis E,Asimakidou M,Moxham BJ,Petropoulos AS,Emmanouil-Nikolousi ENdoi
10.1016/j.ijporl.2011.02.018subject
Has Abstractpub_date
2011-05-01 00:00:00pages
695-9issue
5eissn
0165-5876issn
1872-8464pii
S0165-5876(11)00085-1journal_volume
75pub_type
杂志文章abstract：OBJECTIVES:To evaluate the results of a newly introduced technique to our Department of endoscopic assisted transcanal myringoplasty applied in tympanic membrane perforation in children of any age and compare them to that of the previously standard microscopic assisted myringoplasty technique. METHODS:A retrospective ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2015.08.025
更新日期：2015-11-01 00:00:00
abstract：:Otofaciocervical syndrome (OFCS) is a rare disorder characterized by facial, ear, branchial, and musculoskeletal anomalies, along with hearing loss and mild intellectual disability. Clinically, its distinction from branchiootorenal syndrome can be difficult. To date, the coexistence of OFCS and metachondromatosis has ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2016.03.021
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVES:To determine the role of laryngotracheal reconstruction for recurrent croup and evaluate surgical outcomes in this cohort of patients. METHODS:Retrospective chart review at a tertiary care pediatric hospital. RESULTS:Six patients who underwent laryngotracheal reconstruction (LTR) for recurrent croup with u...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2016.01.006
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVES:In many studies evaluating the effect of sequential bilateral cochlear implantation in congenitally deaf children, device use is not taken into account. In this study, however, device use was analyzed in relation to auditory brainstem maturation and speech recognition, which were measured in children with ea...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2016.05.003
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVES:The main objective was to examine the effect of central maturation on the auditory temporal resolution in a group of school-age children using Gaps-In-Noise test. METHODS:The study involved 180 children (6-16 years) with normal hearing, average intelligence and language skills, and adequate scholastic achie...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2019.04.010
更新日期：2019-07-01 00:00:00
abstract：:Humans are born 12 months too early. Gestation should be 21 months. Humans evolved to become the pre-eminent animal in the world, but our big brain, bipedalism, and small female pelvic outlet have caused us to pay the price of being born too soon with all of its disadvantages. Early birth has an impact on diseases and...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.ijporl.2004.07.021
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVES:To identify etiologies of congenital nasal obstruction and describe clinical practice patterns in the evaluation, diagnosis, and treatment of symptomatic infants. METHODS:An electronic chart review from 1/1/2006-10/1/2016 for all patients with a diagnosis of nasal obstruction within the first six months of ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.ijporl.2017.05.023
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to analyze HRCT and MRI findings in patients with X-linked non-syndromic deafness and a POU3f4 mutation. METHODS:HRCT and MRI data of four patients (males, 2-19 years old) with a POU3f4 mutation were collected and a retrospective review was performed. Cochlea, internal auditory cana...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2014.08.013
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:We report a rare, silent, potentially fatal operative complication of seven hour apnoea in a patient undergoing adenotonsillectomy secondary to deficiency of plasma cholinesterase. Awareness of this hereditary disorder is important to otolaryngologist as; it is difficult to diagnose, can be unexpectedly alarm...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.ijporl.2011.10.010
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To assess global trends in otolaryngologic and non-otolaryngologic education in response to COVID-19, specifically with regard to surgical simulation and personnel reallocation needs in case of patient demand. STUDY DESIGN:Online survey. METHODS:A multiple-choice survey regarding operative caseload and impa...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2020.110267
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVES:To characterize otologic management of two patient groups, those with the CHARGE association and those not strictly labeled as CHARGE but with several features of the disorder (CHARGE-like), in order to determine: (1) the clinical validity and utility of managing CHARGE-like children in a similar manner to p...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s0165-5876(98)00064-0
更新日期：1998-07-10 00:00:00
abstract：OBJECTIVE:This study aimed to evaluate any potential effects of phototherapy on cochlear function in newborns using transient evoked otoacoustic emissions (TEOAEs). METHODS AND MATERIALS:Fifty-seven newborns, undergoing phototherapy for hyperbilirubinemia without any other risk factors, and a control group of 53 healt...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2014.09.006
更新日期：2014-12-01 00:00:00
abstract：INTRODUCTION:There is increased risk of hearing loss in preterm neonates. This risk is further increased by environmental noise exposure especially from life support equipment such as ventilation. Nasal continuous positive airway pressure (NCPAP) used for respiratory support of preterm neonates is known to be associate...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2012.11.040
更新日期：2013-03-01 00:00:00
abstract：:A total of 163 children were entered into a case-control study to determine whether any causal relationship exists between otitis media with effusion (OME) requiring grommet insertion and parental smoking. One hundred children with persistent OME formed the case group and 63 children with normal ears formed the contro...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/0165-5876(92)90062-t
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVES:Obstructive sleep apnea (OSA) is a common problem in children and is associated with increased cardiovascular, neurobehavioral and somatic growth consequences. Cysteinyl leukotrienes (CysLTs) play a major role with local and systemic relations to the pathophysiology of OSA. The level of CysLTs in urine, bloo...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2017.01.021
更新日期：2017-03-01 00:00:00
abstract：INTRODUCTION:Tonsillectomy is the second most common surgery in children with sickle cell disease. These children are at an increased risk of perioperative complications due to vaso-occlusive events. Although controversial, preoperative blood transfusions are sometimes given in an effort to prevent such complications. ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2017.10.013
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:(s): Patient-reported outcome measures (PROMs) are tools that allow patients to directly share information about their health with their healthcare provider. Health literacy experts recommend that health information, such as PROMs, be written at a 6th grade level to ensure patients can read and comprehend it....
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2020.110550
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVES:To describe clinical findings from a multidisciplinary program for children with permanent hearing loss (PHL). METHODS:Retrospective chart review at a tertiary care children's hospital. PATIENTS:Two hundred patients charts were selected from the population of 260 children with permanent hearing loss presen...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2011.05.019
更新日期：2011-08-01 00:00:00
abstract：:In our clinical series, 40-50% O2 and 50-60% N2O (regulated by a blender and delivered by manual jet ventilation (MJV] and residual halothane from induction provided satisfactory supralaryngeal anesthesia. Fentanyl, N2O, atracurium, and lidocaine administered i.v. effectively blunted laryngeal stimulation, allowed con...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/0165-5876(87)90051-6
更新日期：1987-11-01 00:00:00
abstract：OBJECTIVES:To establish a hearing screening program with high coverage, low referral rate, high follow-up rate, and early intervention in Taipei City. METHODS:From September 2009 to December 2010, 85% delivery units in Taipei City, which includes 20 hospitals and 14 obstetrics clinics, were recruited into the screenin...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijporl.2013.08.004
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVES:Bimodal fitting (BF) allows children with cochlear implant to benefit from binaural hearing advantages. Three major binaural hearing advantages, which enhance hearing function of people with normal hearing, are head shadow effect (HSE), binaural squelch effect (BSQ) and binaural summation effect (BSU). This ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2019.02.043
更新日期：2019-06-01 00:00:00
abstract：INTRODUCTION:Sleep Disordered Breathing (SDB) is a highly prevalent condition associated with orofacial and dentofacial characteristics. OBJECTIVE:The aim of this study was to verify the association of dental malocclusion, molar relationship, crossbite, open bite, overjet, overbite, and crowding with SDB in children a...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2014.08.040
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To investigate whether the effects of sex (male/female) that have been demonstrated in the pathology literature using 0.1 mm histopathologic slices are measurable and statistically significant using high-resolution (0.625 mm slice) computed tomography (CT). METHODS:IRB-approved retrospective analysis of high...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2013.04.013
更新日期：2013-07-01 00:00:00
abstract：:Squamous cell carcinoma of the hypopharynx is extremely rare in children. We present a 13-year-old girl with squamous cell carcinoma of the hypopharynx whose father was a coal-miner and a heavy smoker. ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2005.01.026
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:This study assessed the development of balance function in children using platform stabilometry. METHODS:A total of 251 healthy children aged from 3 to 12 years were enrolled in this study. Each subject underwent stabilometry under four various conditions (A: firm surface with eyes open; B: firm surface with...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2009.01.016
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVES:Otogenic lateral sinus thrombosis is a rare complication of acute otitis media whose clinical presentation has changed with the early use of antibiotics. The aim of this study was to analyze the changing clinical signs, vaccination status, therapeutic management and outcome of these patients. METHODS:Retros...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2014.05.001
更新日期：2014-08-01 00:00:00
abstract：:Four cases of laryngeal dysfunction are presented. The substantial advantages derived from the use of flexible fiberoptic instruments in children is described, together with a description of 3 scopes developed by the author. ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s0165-5876(83)80045-7
更新日期：1983-07-01 00:00:00
abstract：:Upper respiratory infections (URI) during the first years of life are mostly viral in origin. However, a number of observations suggest the influence of both predisposing and triggering factors. Atopy in particular seems to play an important role as do environmental factors. Many children with early symptoms such as b...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/0165-5876(92)90137-e
更新日期：1992-09-01 00:00:00
abstract：:The Stevens-Johnson syndrome (SJS) is a severe variant of erythema multiforme (EM) that occasionally can rise to systemic upset and possibly compromise life. In this report, we described important oral and dermatologic aspects of a case of SJS triggered by Mycoplasma pneumoniae infection. ...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.ijporl.2012.10.019
更新日期：2013-02-01 00:00:00
abstract：:This study analyzed the occurrence of negative middle ear pressure in various groups of children by comparing them with control groups. A screening procedure recording middle ear pressure and screening audiogram was performed several times throughout the year in an unselected group of 352 seven-year-old children. From...
journal_title：International journal of pediatric otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/0165-5876(79)90015-6
更新日期：1979-12-01 00:00:00
